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Case Report: Leaflet thrombosis after transcatheter valve-in-valve aortic valve replacement in prosthetic valve endocarditis

Frontiers in Cardiovascular Medicine

A computed tomography revealed subclinical leaflet thrombosis. The patient was deemed unsuitable for surgery by the heart team, following which she underwent transcatheter aortic valve-in-valve replacement. This resulted in early death due to myocardial infarction and acute heart failure.

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New wearable cardiac acoustic monitoring technology for evaluation of subclinical leaflet thrombosis after transcatheter aortic valve replacement

Heart BMJ

Background Subclinical leaflet thrombosis (SLT) is a common complication after transcatheter aortic valve replacement (TAVR). Multidimensional CT (MDCT) is the main imaging mortality for the diagnosis of SLT but it enhances the risk of contrast-induced nephropathy.

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Study shows how high blood sugar increases risk of thrombosis

Medical Xpress - Cardiology

A study conducted at the Center for Research on Redox Processes in Biomedicine (Redoxoma) helps understand how high blood sugar (hyperglycemia), one of the manifestations of diabetes, can cause thrombosis.

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The gut microbiota in thrombosis

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 17 September 2024; doi:10.1038/s41569-024-01070-6 The gut microbiota has emerged as a risk factor that affects thrombotic phenotypes in several cardiovascular diseases.

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Optimal antithrombotic therapy after transcatheter aortic valve replacement: a comprehensive review

Frontiers in Cardiovascular Medicine

Subclinical leaflet thrombosis is observed in 10%20% of patients, though its clinical significance remains uncertain. Clinical valve thrombosis is rare. Ongoing trials aim to clarify optimal antithrombotic regimens and strategies for preventing subclinical leaflet thrombosis.

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JACC Topic of the Week Review Details Pharmacotherapy Algorithm For TAV Thrombosis

American College of Cardiology

For the treatment of transcatheter aortic valve (TAV) thrombosis, both in its more common form of subclinical leaflet thrombosis (SLT) and the rarer clinical valve thrombosis (CVT), pharmacotherapy with vitamin K antagonists (VKA), non-vitamin K oral anticoagulants (NOAC) and an ultraslow, low-dose infusion of thrombolytics should be considered as (..)

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Diagnosis and Management of Cerebral Venous Thrombosis: A Scientific Statement From the American Heart Association

Stroke Journal

Cerebral venous thrombosis accounts for 0.5% The clinical presentation of cerebral venous thrombosis is diverse (eg, headaches, seizures), requiring a high level of clinical suspicion. The clinical course of cerebral venous thrombosis may be difficult to predict. Stroke, Ahead of Print. to 3% of all strokes.