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Case Report: First attempt by off-label use of tenecteplase to treat acute extensive portal venous system thrombosis

Frontiers in Cardiovascular Medicine

Acute extensive portal venous system thrombosis (PVST) can cause lethal complications. Herein, we have for the first time reported the use of anticoagulation combined with systemic thrombolysis by tenecteplase in a male patient with a diagnosis of acute extensive PVST but without liver cirrhosis.

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Prospective Multicenter International Registry of Ultrasound-Facilitated Catheter-Directed Thrombolysis in Intermediate-High and High-Risk Pulmonary Embolism (KNOCOUT PE)

Circulation: Cardiovascular Interventions

BACKGROUND:Prior clinical trials have demonstrated the efficacy of ultrasound-facilitated catheter-directed thrombolysis (USCDT) for the treatment of acute intermediate-risk pulmonary embolism (PE) using reduced thrombolytic doses and shorter infusion durations. Circulation: Cardiovascular Interventions, Ahead of Print.

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Which one is the best in treating deep venous thrombosis —— percutaneous mechanical thrombectomy, catheter-directed thrombolysis or combination of them?

Journal of Cardiothoracic Surgery

To compare the treatment outcomes among percutaneous mechanical thrombectomy (PMT) with AngioJet, Catheter-directed thrombolysis (CDT), and a combination of both.

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Early Reperfusion

EMS 12-Lead

Coronary thrombosis is a dynamic process of platelet aggregation and subsequent coagulation. During spontaneous reperfusion -- whether via thrombolysis, or recruitment of collateral circulation -- there exists characteristic ST/T changes on the ECG. Case Review: [link]

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Abstract TP278: Identifying High-Risk Patients With Poor Prognosis in Acute Phase of Ischemic Stroke: Treatment-Specific Risk Scales Developed From the National Neurological Medical Center of China

Stroke Journal

Subjects were divided into "intravenous thrombolysis group" and "non-intravenous thrombolysis group". Result:A total of 1971 patients (437 thrombolysis) were included. In the external validation set, the AUC-ROC values of "PAIST Scale" were 0.855 in the non-thrombolysis group and 0.778 in the thrombolysis group.

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Case Report: PROS1 (c.76+2_76+3del) pathogenic mutation causes pulmonary embolism

Frontiers in Cardiovascular Medicine

Ultrasound showed no thrombosis in the veins of both lower limbs. The patient's father and grandfather have a history of lower limb venous thrombosis. The patient was treated with heparin anticoagulant therapy, catheter thrombus aspiration, and catheter thrombolysis. 76+2_76+3del) gene is extremely rare.

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Abstract WP154: Factors Associated With Prolonged Length of Intensive Unit Stay Following Mechanical Thrombectomy for Acute Ischemic Stroke

Stroke Journal

vs. 6.1%, p = 0.0002), deep vein thrombosis (7.3 Patients receiving thrombolysis prior to thrombectomy were less likely to have a prolonged LOS (27.8% p = 0.0002), not receiving IV thrombolysis (OR 2.3, vs. 5.7%, p = 0.0200), intubation for the procedure (86.7% vs. 69.3%, p = 0.0001), complications including pneumonia (18.5%

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