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Shortly after isoprenalin infusion was initiated, there were short runs of ventricular tachycardia. The granulomatous inflammation affects the heart, causing an infiltrative cardiomyopathy The most common manifestations of cardiac sarcoidosis are atrioventricular (AV) block and ventricular tachyarrhythmias (VT).
IMPRESSION: Given the presence of a wide tachycardia — with 2 distinct QRS morphologies, and no sign of P waves — a presumed diagnosis of B i D irectional Ventricular Tachycardia has to be made. And , the patient is older (ie, prone to reduced renal function ) — and he is taking Digoxin.
Inflammation within the stellate ganglia has been observed in patients with suddencardiacdeath after MI,4,5 long QT syndrome and catecholaminergic polymorphic ventricular tachycardia,6 and electrical storm,7 suggesting a link between inflammation within these ganglia and ventricular arrhythmogenesis.
The effects of SGLT2i on atrial fibrillation(AF), atrial flutter(AFL), composite AF/AFL, ventricular fibrillation(VF), ventricular tachycardia(VT), ventricular extrasystoles(VES), suddencardiacdeath(SCD) and composite VF/VT/SCD were evaluated. RCTs comparing SGLT2i with placebo were included.
Implantable cardioverter defibrillator (ICD) prevents suddencardiacdeath (SCD) in patients with ischemic cardiomyopathy (ICM). Catheter ablation has been shown to effectively reduce ventricular tachycardia (VT) recurrence, yet its efficacy in patients without an ICD implantation remains uncertain.
Possible arrhythmic recurrences and the risk of suddencardiacdeath (SCD) in this setting are reasons for concern, and limited data have been published to guide clinical management of these patients. Background Ventricular arrhythmias (VAs) frequently occur in the acute phase of myocarditis. to 0.53, p=0.13).
Patients with repaired tetralogy of Fallot are at risk of ventricular tachycardia (VT) and suddencardiacdeath. Most VTs arise from 5 slowly conducting anatomic isthmuses (SCAIs; conduction velocity ≤0.5 m/s) bound by the right ventriculotomy, ventricular septal defect patch, and tricuspid and pulmonic valves.
Subcutaneous implantable cardioverter-defibrillators (S-ICDs) alleviate many issues associated with a transvenous system, while having similar efficacy to transvenous ICDs at preventing suddencardiacdeath. However, S-ICDs have higher rates of shocks due to a lack of anti-tachycardia pacing (ATP).
Brugada syndrome (BrS) is a primary arrhythmia syndrome associated with suddencardiacdeath.1 2 However, no studies have evaluated the role of genetics separately for ventricular fibrillation (VF) and monomorphic ventricular tachycardia (MVT).
Recent advancements in catheter ablation for structural ventricular tachycardia (VT), such as high-density mapping and cardiac imaging-based detection of target areas, have significantly improved the efficacy of ablation procedures.
He is afebrile on arrival, with mild sinus tachycardia. He is afebrile on arrival, with mild sinus tachycardia. HPI: A 55-year-old man with no significant PMHx (on no medications) presents to the emergency department with right lower quadrant pain. He is found to have perforated appendicitis and is admitted for operative intervention.
Heart failure and suddencardiacdeath (SCD) are two major causes of cardiacdeath in patients with light-chain cardiac amyloidosis (AL-CA). The role of premature ventricular contractions (PVC) and non-sustained ventricular tachycardia (NSVT) in predicting SCD or cardiacdeath in AL-CA is not well-defined
Ventricular tachycardia (VT) is a common consequence of both ischemic and non-ischemic heart diseases, often leading to suddencardiacdeath. Enhanced sympathetic nerve activity has been implicated in the initiation of VT.
Catecholaminergic polymorphic ventricular tachycardia (CPVT) has been identified as a notable cause of suddencardiacdeath in children and young adults.1 1 Mutation of ryanodine receptor 2 (RYR2) is observed in the majority of CPVT patients and is inherited through an autosomal dominant pattern.2
Background Brugada syndrome (BrS) is a channelopathy that can lead to suddencardiacdeath in the absence of structural heart disease. Patients with BrS can be asymptomatic or present with symptoms secondary to polymorphic ventricular tachycardia or ventricular fibrillation. The patient did not have underlying diseases.
Since its identification in 1981 its diagnosis has increased due to the advancements in cardiac imaging. It’s association with ventricular arrythmia (VA) and suddencardiacdeath (SCD) underscores the importance of its identification. Electrocardiogram (ECG) showed sustained monomorphic VT at a rate of 160 bpm.
BACKGROUND:In severely affected patients with catecholaminergic polymorphic ventricular tachycardia, beta-blockers are often insufficiently protective. The primary end point was AEs, defined as suddencardiacdeath, suddencardiac arrest, appropriate implantable cardioverter defibrillator shock, and arrhythmic syncope.
Implantable cardiac defibrillator (ICD) implantation can protect against suddencardiacdeath (SCD) after a myocardial infarction. However, improved risk stratification for device requirement is still needed.
The SCVT is a polymorphic ventricular tachycardia that commonly affects younger patients without structural heart disease that is associated with suddencardiacdeath (SCD).
In patients with DM suddencardiacdeath (SCD) typically from ventricular tachycardia (VT) accounts for as much as 40% of mortality. Mechanisms underlying the genesis of VT in the DM heart remain poorly understood
For the past four decades, implantable cardioverter defibrillator (ICD) therapy has become the standard of care for preventing suddencardiacdeath in high-risk individuals. The rate of ICD implantation has risen due to the increasing population age and the growing prevalence of cardiac arrhythmias.
Suddencardiacdeath often results from monomorphic VT (MVT), polymorphic VT or VF (PVT/VF). Insertable cardiac monitors (ICMs) record single vector ECGs for tachycardias (TACHY). Even with expert clinician review, discriminating VT/VF from SVTs or false detections from oversensing (OS) is challenging.
There is a run of polymorphic ventricular tachycardia — which given the QT prolongation, qualifies as Torsades de Points ( TdP ). This patient was having recurrent episodes of polymorphic ventricular tachycardia with an underlying long QT interval ( = Torsades des Pointes ). ECG #2 Interpretation of ECG #2: Underlying sinus rhythm.
Suddencardiacdeath remains the main killer of adults in industrialized countries and reentrant ventricular arrhythmia (VA) is its main underlying mechanism1.
Tetralogy of Fallot (TOF) represents the poster child for monomorphic ventricular tachycardia (MVT) in congenital heart disease. Sustained MVT affects approximately 10% of such patients at 30 years after cardiac repair and is inextricably related to the burden of suddencardiacdeath (SCD).(1)
The EV ICD Pivotal Trial is a prospective, multicenter, single-arm, non-randomized, pre-market clinical study that assessed the safety and effectiveness of the Medtronic EV-ICD system for patients at risk of suddencardiacdeath. It works by briefly delivering pacing pulses to the heart at a rate faster than the tachycardia.
Significant right ventricular involvement was an exclusion criterion. Results Fifty-two patients (63% males, age 45 years (31–53)) composed the study cohort.
Background Consensus guidelines support the use of implanted cardioverter-defibrillators (ICD) for primary prevention of suddencardiacdeath in patients with either non-ischaemic or ischaemic cardiomyopathy with left ventricular ejection fraction (LVEF) ≤35%. vs 65.4%, p<0.0001), more often white (87.5%
A few decades ago all suddencardiac arrests with documented ventricular fibrillation (VF) and structurally normal hearts were diagnosed as idiopathic ventricular fibrillation (IVF).
Patients with Brugada syndrome who are asymptomatic and have no ventricular tachycardia/ventricular fibrillation inducibility by programmed electrical stimulation are at extremely low risk of experiencing late life-threatening arrhythmias. and 100%, respectively.
An external monitor revealed one episode of non-sustained supraventricular tachycardia, otherwise was unremarkable. He experienced worsening symptoms for which emergency department evaluation revealed anterior lead T-wave inversions on EKG.
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a disease characterised by fibrofatty replacement of the ventricular myocardium due to specific mutations, leading to ventricular arrhythmias and suddencardiacdeath. Emerging evidence suggests that combining flecainide and bisoprolol may be efficacious.
Brugada syndrome is thought to account for about one fourth of suddencardiacdeaths in individuals with structurally normal heart. Even though mutations in other channels have been described in Brugada syndrome, only those in SCN5A gene are considered to be definitely disease causing. mV or R/q ≥ 0.75.
Cardiovascular mortality, driven by suddencardiacdeath, is the main reason for dying while waiting for heart transplantation (HTx). Aims Timely referrals for transplantation and left ventricular assist device (LVAD) play a key role in favourable outcomes in patients with advanced heart failure (HF).
Then, why is it mentioned that, implanting a defibrillator soon after an acute myocardial infarction, in those with left ventricular dysfunction and prone for ventricular arrhythmias and suddencardiacdeath, is not useful? Mostly for protection against suddencardiacdeath. So, this is how an ICD works.
The prediction of suddencardiacdeath remains the ‘holy grail’ of cardiology to enable optimal targeting of preventative therapies in at-risk groups. 1 Although ICDs have proven to be highly efficacious, less than 1 in 10 of the implanted devices are actually needed.
Chagas disease (ChD) was associated with increased rates of ventricular tachycardia and ventricular fibrillation in ICD patients only in the initial two periods, but there was no statistical difference in the last period. Methods This retrospective observational study included patients who received ICDs between October 2007 and December 2018.
See this even more interesting and more dramatic and fascinating case: History of Hypertrophic Cardiomyopathy (HOCM), with Tachycardia and High Lactate = My Comment by K EN G RAUER, MD ( 10/28 /2023 ): = QUESTION: For clarity in Figure-1 — I've reproduced today's ECG without the long lead rhythm strip. If so — WHO to screen?
Otherwise vitals after intubation were only notable for tachycardia. An initial EKG was obtained: Computer read: sinus tachycardia, early acute anterior infarct. 2017 AHA/ACC/HRS guideline for management of patients with ventricular arrhythmias and the prevention of suddencardiacdeath.
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