Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP16-AWP16, February 1, 2024. Introduction:Trials using advanced imaging have shown a benefit from intravenous thrombolysis in patients with wake-up stroke, but real-world data is limited. in those able to receive perfusion imaging). in those able to receive perfusion imaging).

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DAIC

MAY 14, 2024

UVA Health's Karen Johnston, MD, the SHINE trial leader, was pleased to see the new insights into best practices for stroke care. These data from the SHINE trial continue to inform the national stroke community about potential approaches to treating hyperglycemic stroke patients to assure better outcomes,” she said.

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Stroke Strokes Thrombolysis Hemorrhage 105

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP100-AWP100, February 1, 2024. Introduction:IV thrombolysis is a proven treatment for acute ischemic stroke (AIS), but it is still underutilized in real-world clinical practice. Urgent interventions to increase IV thrombolysis rates are needed to improve acute stroke care.

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Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A43-A43, February 1, 2024. hours of ischemic stroke onset from 2003 to 2021. hours of ischemic stroke onset from 2003 to 2021. Thrombolysis rates and speed of treatment during TS phase I (2010-2013), II (2014-2018), and III (2019-2021) were compared with the pre-TS period (2003-2009).Results:Among

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Stroke: Vascular and Interventional Neurology

MARCH 8, 2024

Stroke: Vascular and Interventional Neurology, Ahead of Print. Among 51% of countries surveyed, no acute thrombolytic treatment was provided for acute stroke in the 2021 calendar year. Most respondents (88%) agreed there were barriers to acute stroke thrombolysis in the region.

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Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP107-ATP107, February 1, 2024. Introduction:Emergency-department-based implementation strategies to increase thrombolysis are promising. The study population was limited to ischemic stroke patients admitted to the hospital. Among 1608 hospitals, 1131 (70%) had tPA rates below 10%.

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Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP115-ATP115, February 1, 2024. Background:The SouthEast Texas Regional Advisory Council (SETRAC) has actively engaged representatives from regional healthcare systems who collectively work towards advancing stroke care delivery. The rates of thrombolysis increased from 7.10% in 2014 to 11.8%

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Medical Xpress - Cardiology

FEBRUARY 12, 2024

nationwide quality initiative Target: Stroke (TS) is associated with improvement in thrombolysis frequency, timeliness, and outcome, according to a study published online Feb. 7 in JAMA Network Open.

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Thrombolysis Stroke Strokes Outcomes 40

Journal of the American Heart Association

DECEMBER 18, 2023

BackgroundIntravenous thrombolysis (IVT) is an effective stroke therapy that remains underused. Finally, sensitivity analysis for idarucizumab, National Institutes of Health Stroke Scale, and timing of DOAC administration was completed. Journal of the American Heart Association, Ahead of Print. versus 3.5%; OR, 0.95 [95% CI, 0.67–1.36]),

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Thrombolysis Strokes Stroke Hemorrhage 75

Journal of the American Heart Association

MARCH 8, 2024

Journal of the American Heart Association, Ahead of Print. We performed sensitivity analysis using propensity score matching. 0.75];P=0.001).

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Thrombolysis Outcomes Stroke Strokes 45

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. IntroductionOver the past decade, stroke management has significantly improved with the widespread use of intravenous thrombolysis (IVT) and the establishment of endovascular thrombectomy (EVT) as the standard of care for increasing patients.

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Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP117-ATP117, February 1, 2024. Introduction:Reducing door-to-needle (DTN) times lead to improved patient outcomes in acute ischemic stroke. 2) Creation of a multidisciplinary Thrombolysis Focus Group to analyze data and improve processes. in 2020, to 31.9% in 2021, to 59.6%

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Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A26-A26, February 1, 2024. The access to acute stroke treatments, especially intravenour thrombolysis and mechanical thrombectomy, is limited. The average stroke centres per million (SCPM) population was 0.41 for IVT-C and EVT-C, respectively. hours, respectively.

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Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP270-ATP270, February 1, 2024. Objective:A proportion of acute ischemic stroke (AIS) patients suffer from early neurological deterioration (END) within 24 hours following intravenous thrombolysis (IVT), which greatly increases the risk of poor prognosis of these patients.

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Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP213-ATP213, February 1, 2024. Background and Purpose:Although intra-arterial thrombolysis (IAT) is widely used as adjunct with mechanical thrombectomy in acute ischemic stroke patients, the patients who are likely to benefit are not known. in group A and 3.25±2.01 in group B (p=0.002).

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Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP20-AWP20, February 1, 2024. Importance:Tenecteplase use is more prevalent as the thrombolytic drug of choice for acute ischemic stroke, with results demonstrating its non-inferiority compared to alteplase.

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Hemorrhage Thrombolysis Strokes Stroke 40

Stroke Journal

MARCH 11, 2024

Stroke, Ahead of Print. NETs are proposed as a mechanism of resistance to thrombolysis. Thrombolysis was remarkably associated with higher NE positivity (average marginal effect, 6.461 [95% CI, 0.7901–12.13];P=0.02555), regardless of the origin of thrombi. The therapy that is currently administered does not modify NET content.

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Thrombolysis Pharmacology Strokes Stroke 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A22-A22, February 1, 2024. Introduction:The benefit of intravenous thrombolysis for acute ischemic stroke declines with longer time from symptom onset. Intravenous thrombolysis showed clinical benefit if it was administered within 2h 20min after symptom onset.

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Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATMP13-ATMP13, February 1, 2024. Introduction:Recent studies report similar outcomes with antiplatelet drugs and intravenous thrombolysis (IVT) in patients with minor nondisabling ischemic stroke.

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Medical Xpress - Cardiology

DECEMBER 13, 2023

Renal dysfunction, especially chronic kidney disease, is the biggest risk factor of mortality among thrombolysed stroke patients, according to a retrospective cohort observational study published in Medicine.

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DAIC

FEBRUARY 26, 2024

Kulcsar, University Hospital Zurich milla1cf Mon, 02/26/2024 - 12:13 February 26, 2024 — Ischemic strokes are a major health burden. Many stroke patients recover poorly despite timely treatment To treat these symptoms and restore blood flow to the brain, the obstructed vessel needs to be “declogged”, or recanalized.

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DAIC

FEBRUARY 7, 2024

Findings from the highly-anticipated MOST (Multi-Arm Optimization of Stroke Thrombolysis) trial were presented on the first day of the American Stroke Association’s International Stroke Conference, ISC 2024, being held through Feb. A lot of our approaches in stroke treatment were learned from how we treat heart attacks.

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Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP5-AWMP5, February 1, 2024.

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ADN Center of Excellence

OCTOBER 28, 2024

On October 29th, the global community observes World Stroke Day , an occasion dedicated to raising awareness about one of the most formidable threats to global health: stroke. Often called the "silent killer," stroke is a leading cause of death and disability worldwide.

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Stroke Journal

JANUARY 4, 2024

Stroke, Ahead of Print. BACKGROUND:The effectiveness of intravenous thrombolysis (IVT) before endovascular treatment (EVT) has been investigated in randomized trials and meta-analyses. These studies mainly concerned anterior circulation occlusions. All patients with a posterior circulation occlusion were included.

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ECG Cases

JULY 4, 2017

In this two part EM Cases Journal Jam podcast Justin Morgenstern, Rory Spiegel and Anton Helman do a deep dive into the world's literature on systemic thrombolysis for ischemic stroke followed by an analysis of endovascular therapy for stroke.

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Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP93-AWMP93, February 1, 2024. Introduction:Comprehensive Stroke Centers are skilled, highly trained facilities that provide advanced care to an array of stroke patients. minutes), compared to the Comprehensive Stroke Centers (Median: 39.50) (Mann Whitney U-Test: p <0.0001).

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Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A25-A25, February 1, 2024. Introduction:Intravenous thrombolysis (IVT) is efficacious treatment of acute ischemic stroke (AIS). However, certain circumstances associated with increased bleeding risk, such as recent direct oral anticoagulation (DOAC) intake limits its use.

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Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A59-A59, February 1, 2024. Introduction:Many patients are taking antiplatelet medications when an acute stroke occurs. The exposure of interest was pre-stroke antiplatelet use categorized as none, single (SAPT), and dual antiplatelet therapy (DAPT). no antiplatelet, 36.7% SAPT, and 6.4%

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Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. IntroductionEfficacy and safety of intravenous thrombolysis (IVT) in patients undergoing mechanical thrombectomy (MT) is still debatable. ResultsWe included four randomized controlled trials with 1176 patients.

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Thrombolysis Outcomes Embolism Stent 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP42-AWMP42, February 1, 2024. Background:Prior studies have shown that individuals who have an in-hospital stroke are less likely to receive thrombolysis. Out of hospital strokes were patients who were not admitted to the hospital when their stroke symptoms.

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Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP202-AWP202, February 1, 2024. Background:Mechanical thrombectomy (MT) has demonstrated superiority over medical therapy for acute ischemic stroke (AIS) with large vessel occlusion (LVO).

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Thrombolysis Academic Hemorrhage Outcomes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A106-A106, February 1, 2024. Background:Circulating interleukin-6 (IL-6) concentrations are elevated in acute stroke but the timing of the IL-6 response in humans is unknown. We used a mobile stroke unit (MSU) to identify IL-6 levels within minutes of symptom onset. pg/mL, respectively.

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Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP199-AWP199, February 1, 2024. Background:The benefits of endovascular thrombectomy (EVT) for posterior cerebral artery (PCA) occlusion remain controversial, but intravenous thrombolysis (IVT) has proven benefit across nearly all ischemic stroke types.

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Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP179-AWP179, February 1, 2024. Background:Stent-retriever thrombectomy is the first-line therapy for acute stroke with intracranial large vessel occlusion. In cases of stent-retriever thrombectomy failure, rescue stent angioplasty might be the sole option for achieving permanent recanalization.

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Stroke: Vascular and Interventional Neurology

APRIL 17, 2024

Stroke: Vascular and Interventional Neurology, Ahead of Print.

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Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. IntroductionImportance:Tenecteplase (TNK) use is more prevalent as the thrombolytic drug of choice for acute ischemic stroke (AIS), given its ease of use with results from randomized trials showing non‐ inferiority and comparable safety to Alteplase (tPA).

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