Medical Xpress - Cardiology

SEPTEMBER 13, 2024

A review in The Lancet finds that 20% of the world population carries a genetic risk factor for cardiovascular diseases such as heart attacks, strokes, and aortic valve stenosis: Increased levels of a lipid particle called lipoprotein(a). It is the most common genetic cause of cardiovascular diseases.

Aortic valve 86

Aortic valve Heart Disease Heart attacks Heart Attack 86

Stroke Journal

JANUARY 21, 2024

Stroke, Volume 55, Issue 2 , Page 311-323, February 1, 2024. Intracranial atherosclerotic disease (ICAD) is one of the most common causes of stroke worldwide. In addition to stroke, ICAD increases the risk of dementia and cognitive decline, magnifying ICAD societal burden.

Stenosis 74

Stenosis Thrombosis Dementia Stroke 74

Stroke Journal

JUNE 26, 2024

Stroke, Ahead of Print. Asymptomatic high-grade carotid stenosis is an important therapeutic target for stroke prevention. Advances in treatments against atherosclerosis have driven down the rates of stroke in patients managed without revascularization.

Stenosis 40

Stenosis Stents Stent Atherosclerosis 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP299-ATP299, February 1, 2024. PR was calculated as the ratio of proximal to distal pressure at the stenosis site, indicating post-stenosis blood flow. Arterial stenosis severity was categorized using the WASIDMethod:50%-69% for moderate and 70%-99% for severe. PR > 0.76

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Stenosis Stents Stent Stroke 40

Stroke Journal

JANUARY 21, 2024

Stroke, Volume 55, Issue 2 , Page 324-334, February 1, 2024. Intracranial atherosclerotic stenosis is a prevalent cause of ischemic stroke worldwide. This review focuses on randomized secondary prevention trials involving antithrombotic therapy, endovascular treatment, open surgical therapy, and remote ischemic conditioning.

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Stenosis Dementia Stroke Strokes 40

Stroke Journal

JANUARY 21, 2024

Stroke, Volume 55, Issue 2 , Page 335-343, February 1, 2024. Reducing the high risk of recurrent stroke in patients with symptomatic intracranial atherosclerotic stenosis (sICAS) has proven to be challenging, but aggressive medical management, with intensive risk factor control and antithrombotic therapy, has been shown to be beneficial.

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Stenosis Blood Pressure Diet Risk Factors 40

Stroke Journal

JANUARY 21, 2024

Stroke, Volume 55, Issue 2 , Page 344-354, February 1, 2024. Intracranial atherosclerotic disease and resultant intracranial stenosis is a global leading cause of stroke, and poses an ongoing treatment challenge.

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Stenosis Risk Factors Technology Stroke 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP142-AWP142, February 1, 2024. Background:Intracranial atherosclerotic disease (ICAD) is associated with high recurrence rates of stroke despite aggressive medical management. Arterial segments extending from the stenosis to the MCA bifurcation were captured and quantified. mm2p=0.298).Conclusion:Area

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Stenosis Stroke Strokes 40

Medical Xpress - Cardiology

SEPTEMBER 3, 2024

Transcatheter aortic valve implantation (TAVI) was superior to surgical aortic valve replacement for reducing death, stroke or rehospitalization in women with severe aortic stenosis, according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

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Aortic valve Aortic Stenosis Research 75

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP220-ATP220, February 1, 2024. The Tenzing was slowly inserted across the ICAD stenosis in each case under roadmap fluoroscopic guidance. Stenosis location was: 1 ICA, 7 M1, 4 M2, 2 vertebral. All patients were treated using the Tenzing 7 delivery catheter in an off-label fashion.

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Angioplasty Stenosis Stents Stent 40

Frontiers in Cardiovascular Medicine

DECEMBER 12, 2024

However, its postoperative complications can have a significant effect on long-term patient outcomes. 33 preoperative clinical features and 4 postoperative complications were collected in each group.

Coronary Artery Bypass Graft 52

Coronary Artery Bypass Graft Stroke Strokes Aortic 52

American College of Cardiology

OCTOBER 29, 2024

The goal of the PROTECTED TAVR trial was to evaluate the efficacy of intraprocedural cerebral embolic protection (CEP) in reducing strokes among patients undergoing transfemoral TAVR for aortic stenosis.

Aortic valve 45

Aortic valve Aortic TAVR Stroke 45

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP174-ATP174, February 1, 2024. The standardized mean difference (SMD) for post-procedure stenosis (%) was significantly lower (SMD: -0.52, 95% confidence interval [CI]: -0.79 The odds for post-procedure 30-day stroke and/or death were significantly lower (OR 0.68, 95% CI: 0.50-0.94,

Stents 40

Stents Stent Stenosis Stroke 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP116-AWMP116, February 1, 2024. Introduction:Medical treatment of internal carotid artery stenosis consists of treatment of underlying conditions such as hypertension, dyslipidemia, and diabetes mellitus, as well as antiplatelet therapy.

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Stenosis Aneurysm Diet Cholesterol 40

DAIC

MAY 15, 2024

In the meta-analysis of seven randomized trials, published in JSCAI and presented at the 2024 EuroPCR conference in Paris, France, researchers compared the outcomes of 7,785 patients undergoing TAVR (a procedure that delivers a new aortic valve into the heart through a catheter) to those undergoing SAVR for severe aortic stenosis.

Aortic valve 105

Aortic valve TAVR Outcomes Aortic 105

Cardiology Update

FEBRUARY 11, 2024

The NOTION trial, a pioneering study, sought to compare the long-term clinical and bioprosthesis outcomes of Transcatheter Aortic Valve Implantation (TAVI) versus Surgical Aortic Valve Replacement (SAVR) in patients with severe aortic valve stenosis (AS) at lower surgical risk.

Aortic valve 124

Aortic valve Aortic Outcomes Thrombosis 124

Frontiers in Cardiovascular Medicine

NOVEMBER 19, 2024

In addition, severe ACAS was related to an increased rate of 30-day postoperative major adverse cardiovascular and cerebral events (MACCEs), including a 30-day postoperative stroke. Also, severe ACAS may be independently associated with 30-day postoperative stroke (OR, 2.83, 95% CI 1.03–7.75, 14.30, p < 0.0001) after OPCAB.

Coronary Artery Bypass Graft 52

Coronary Artery Bypass Graft Stenosis Coronary Artery Disease Ultrasound 52

Open Heart

FEBRUARY 1, 2022

Objectives To investigate the reliability and agreement of hand-held ultrasound devices (HUDs) compared with conventional duplex ultrasound (HIGH) in examination for carotid stenosis in patients with suspected transitory ischaemic attack (TIA) or ischaemic stroke.

Ultrasound 52

Ultrasound Stenosis Stroke Strokes 52

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. IntroductionIntracranial atherosclerotic disease (ICAD) induces the luminal narrowing of an intracranial vessel and represents one of the major causes of ischemic strokes [1, 2, 3, 4].

Stenosis 40

Stenosis Angioplasty Anatomy Plaque 40

American College of Cardiology

OCTOBER 28, 2024

Findings from the TAVR UNLOAD trial found preemptive TAVR was not superior to clinical aortic stenosis surveillance (CASS) for the hierarchical occurrence of all-cause death, disabling stroke, disease-related hospitalizations and heart failure equivalents, and change in quality of life among patients with moderate aortic stenosis (AS) and heart failure (..)

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TAVR Quality of Life Heart Failure Stenosis 65

Heart BMJ

JANUARY 10, 2024

Objective The optimal medical therapy after surgical aortic valve replacement (SAVR) for aortic stenosis remains unknown. Methods All patients undergoing SAVR due to aortic stenosis in Sweden 2006–2020 and surviving 6 months after surgery were included.

Aortic valve 40

Aortic valve Aortic ACE Inhibitor Stenosis 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. IntroductionExpert consensus guidelines recommend low‐density lipoprotein cholesterol (LDL‐C) as the primary serum lipid target for recurrent stroke risk reduction.

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Stenosis Cholesterol Stroke Strokes 40

Cardiology Update

MARCH 25, 2024

Interestingly, while rates of all-cause mortality did not differ significantly between PCI and CABG groups, PCI was associated with lower early stroke rates. Patients were stratified based on diabetes status, and various outcome measures were assessed using Kaplan-Meier event rates and Cox model hazard ratios.

Diabetes 122

Diabetes Coronary Artery Bypass Graft Outcomes Coronary Artery Disease 122

Open Heart

MAY 12, 2023

Objective To evaluate whether transcatheter or surgical aortic valve replacement (TAVR or SAVR) affects clinical and haemodynamic outcomes in symptomatic patients with moderately-severe aortic stenosis (AS). At 24 months, the rates of death or disabling stroke were similar (TAVR 7.7% <aortic valve area (AVA)<1.5 cm 2 , 3.0<peak

Aortic valve 52

Aortic valve Aortic Stenosis TAVR 52

Stroke Journal

SEPTEMBER 25, 2024

Stroke, Ahead of Print.

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Stroke Strokes Stenosis 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. Duplex US revealed 80‐99% stenosis of both right and left proximal internal carotid arteries. The constellation of findings was most suggestive of bilateral limb‐shaking TIA secondary to bilateral carotid stenosis.

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Stenosis Cerebrovascular Disease Diabetes Stroke 40

Stroke Journal

NOVEMBER 1, 2023

Stroke, Volume 54, Issue 12 , Page 3030-3037, December 1, 2023. BACKGROUND:Inflammation contributes to atherosclerosis but is incompletely characterized in intracranial large artery stenosis (ICAS). We dichotomized ICAS as either ≥50% stenosis or not (including no ICAS).

Stenosis 40

Stenosis Atherosclerosis Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP116-AWP116, February 1, 2024. Compared with contralateral carotid artery plaque, plaque burden at the ipsilateral carotid artery was much heavy, presented with a higher degree of stenosis, smaller lumen area (0.22±0.15 of them were male. 0.15), larger wall area (0.50±0.19

Plaque 40

Plaque Atherosclerosis Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A48-A48, February 1, 2024. Objective:To compare the 1-month stroke, myocardial infarction (MI), and/or death rates among symptomatic patients undergoing either CAS or CEA according to the timing of the procedure in Carotid Revascularization Endarterectomy versus Stenting Trial (CREST).Methods:We

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Stents Stent Stenosis Myocardial Infarction 40

DAIC

JANUARY 29, 2024

Getty Images milla1cf Mon, 01/29/2024 - 14:24 January 29, 2024 — Despite national guidelines recommending surgical aortic valve replacement (SAVR) for patients under age 65 with severe aortic stenosis , many hospitals are still opting for a nonsurgical approach in patients under 60—possibly with poorer survival rates.

Aortic valve 111

Aortic valve TAVR Aortic Outcomes 111

Stroke Journal

JANUARY 8, 2024

Stroke, Ahead of Print.

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Stenosis Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP185-ATP185, February 1, 2024. Primary outcomes included stroke, intracerebral hemorrhage (ICH), and mortality rates at 1-, 6-, 12-, and 18-month follow-ups, and in-stent restenosis. Multivariable logistic regression identified predictors of stroke and mortality.

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Stents Stent Stenosis Stroke 40

Coronary Artery Disease Journal

MAY 13, 2024

Objective To investigate the impact of prior coronary artery bypass grafting (CABG) and coronary lesion complexity on transcatheter aortic valve replacement (TAVR) outcomes for aortic stenosis. Conclusion Prior CABG may positively affect mid-term TAVR outcomes for aortic stenosis compared with no CAD when adjusted for other comorbidities.

Coronary Artery Bypass Graft 40

Coronary Artery Bypass Graft Aortic valve Aortic Stenosis 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A36-A36, February 1, 2024. Background and Objectives:This study aimed to investigate the association between high-resolution magnetic resonance imaging (HR-MRI) characteristics and recurrent ipsilateral stroke in patients with symptomatic intracranial atherosclerotic steno-occlusive disease (ICAS).Methods:This

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Stroke Strokes Plaque Stenosis 40

DAIC

APRIL 11, 2024

All patients enrolled in the trial were eligible for either TAVR or SAVR and had similar characteristics in terms of the severity of aortic stenosis (narrowing of the valve which makes it harder for blood to flow efficiently) and a similar balance of risks and benefits expected with either type of procedure.

TAVR 111

TAVR Aortic valve Aortic COVID-19 111

DAIC

MARCH 28, 2024

The primary safety endpoint was incidence of early onset (within seven days) primary adverse events; atrio-esophageal fistula (within 90 days); cardiac tamponade or perforation (within 30 days); and PV stenosis (within 12 months). Int J Stroke. Erratum in: Int J Stroke. February 2-4; Boston. 2021 Feb;16(2):217-221.

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Atrial Fibrillation AFIB Ablation Pulmonary 110

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. IntroductionIntracranial atherosclerotic disease (ICAD) is associated with up to 32% of posterior circulation strokes.1 1 ICAD‐related strokes are at high risk for re‐occlusion following MT.

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Stents Stent Circulation Stroke 40