DAIC

JUNE 4, 2024

The Neuroguard Integrated Embolic Protection (IEP) system is an experimental treatment for carotid artery stenosis, also known as carotid artery disease, a condition in which fatty-waxy deposits known as plaque builds up and blocks the normal flow of blood in the large arteries on either side of the neck.

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Stents Stent Research Stroke 111

Stroke Journal

JANUARY 21, 2024

Stroke, Volume 55, Issue 2 , Page 355-365, February 1, 2024. This comprehensive literature review focuses on acute stroke related to intracranial atherosclerotic stenosis (ICAS), with an emphasis on ICAS-large vessel occlusion.

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Stenosis Stents Stent Risk Factors 66

Stroke Journal

MARCH 23, 2025

Stroke, Volume 56, Issue 4 , Page e114-e118, April 1, 2025. Intracranial atherosclerotic stenosis is a leading cause of stroke with a significant risk of recurrent ischemic events despite aggressive medical management. However, 3 percutaneous angioplasty and stenting randomized trials showed negative or neutral results.

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Angioplasty Stenosis Coronary Artery Disease Stents 40

Medical Xpress - Cardiology

SEPTEMBER 13, 2024

A review in The Lancet finds that 20% of the world population carries a genetic risk factor for cardiovascular diseases such as heart attacks, strokes, and aortic valve stenosis: Increased levels of a lipid particle called lipoprotein(a). It is the most common genetic cause of cardiovascular diseases.

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Aortic valve Heart Disease Heart Attack Heart attacks 90

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP16-AWP16, February 1, 2025. Introduction:Currently, no level A evidence exists for the optimal rescue strategy for cases at high risk for re-occlusion following endovascular thrombectomy (EVT) in acute ischemic stroke. Mean National Institute of Health Stroke Scale (NIHSS) on admission was 16.6;

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Stenosis Thrombolysis Stroke Strokes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATMP57-ATMP57, February 1, 2025. Introduction:Literature demonstrates that nearly one-third of acute ischemic stroke (AIS) patients with large vessel occlusion (LVO) or severe stenosis arrive at the emergency room with mild symptoms, attributed to favourable collateral status.

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Stenosis Stroke Strokes Circulation 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP215-ATP215, February 1, 2025. Background:Carotid stenosis has been associated with stroke and cognitive impairment. It remains unclear if hypometablism, a marker for neurodegeneration, may be in the mechanistic pathway in the association between carotid stenosis and cognitive decline.

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Stenosis Dementia Ultrasound Stroke 40

Stroke Journal

JUNE 26, 2024

Stroke, Ahead of Print. Asymptomatic high-grade carotid stenosis is an important therapeutic target for stroke prevention. Advances in treatments against atherosclerosis have driven down the rates of stroke in patients managed without revascularization.

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Stenosis Stents Stent Atherosclerosis 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP222-AWP222, February 1, 2024. Introduction:Moyamoya is a progressive cerebrovascular disease characterized by stenosis of the cerebral arteries in the anterior circulation and less often the posterior circulation. At time of diagnosis 16 children (67%) had basilar artery stenosis.

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Stenosis Sickle Cell Disease Cerebrovascular Disease Pediatrics 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP286-AWP286, February 1, 2025. Background:Hemodynamic evaluation is crucial in assessing stroke risk in patients with symptomatic intracranial atherosclerotic stenosis (sICAS). Twenty patients (9.6%) experienced ischemic stroke or TIA during the one-year follow-up. before PTAS.

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Stenosis Stroke Strokes Angioplasty 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP219-ATP219, February 1, 2025. However, few reports have discussed CNs in the context of carotid artery stenosis. However, few reports have discussed CNs in the context of carotid artery stenosis. of patients with moderate to severe carotid artery stenosis who underwent CEA.

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Stenosis Plaque Stroke Strokes 40

Stroke Journal

JANUARY 21, 2024

Stroke, Volume 55, Issue 2 , Page 311-323, February 1, 2024. Intracranial atherosclerotic disease (ICAD) is one of the most common causes of stroke worldwide. In addition to stroke, ICAD increases the risk of dementia and cognitive decline, magnifying ICAD societal burden.

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Stenosis Thrombosis Dementia Embolism 74

Medical Xpress - Cardiology

SEPTEMBER 3, 2024

Transcatheter aortic valve implantation (TAVI) was superior to surgical aortic valve replacement for reducing death, stroke or rehospitalization in women with severe aortic stenosis, according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

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Aortic valve Aortic Stenosis Research 75

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page A39-A39, February 1, 2025. Aggressive Medical Management for Preventing Recurrent Stroke in Intracranial Stenosis (SAMMPRIS) trial. Balloon expandable stent (BES) and self-expanding stent (SES) were used in 54 and 224 patients, respectively.

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Stents Stent Stenosis Stroke 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP299-ATP299, February 1, 2024. PR was calculated as the ratio of proximal to distal pressure at the stenosis site, indicating post-stenosis blood flow. Arterial stenosis severity was categorized using the WASIDMethod:50%-69% for moderate and 70%-99% for severe. PR > 0.76

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Stenosis Stent Stents Stroke 40

Stroke Journal

JANUARY 21, 2024

Stroke, Volume 55, Issue 2 , Page 324-334, February 1, 2024. Intracranial atherosclerotic stenosis is a prevalent cause of ischemic stroke worldwide. This review focuses on randomized secondary prevention trials involving antithrombotic therapy, endovascular treatment, open surgical therapy, and remote ischemic conditioning.

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Stenosis Dementia Research Stroke 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP252-AWP252, February 1, 2025. Baseline angiograms were reviewed to assess the presence or absence of intracranial stenosis lesions (IS+ Vs IS-) different than the target occlusion. Bailout strategies were required more often in the IS+ group (34.6% minutes; p=0.018). Vs 3; p=0.036).Conclusions:Our

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Stenosis Outcomes Angioplasty Stent 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP318-ATP318, February 1, 2025. For this study, acute symptomatic was defined as hemispheric ischemic stroke or retinal ischemia ipsilateral to the carotid stenosis, with symptom onset within 24 hours of admission. Lipid-lowering therapies mitigate the risk of atherothrombotic events.

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Stenosis Atherosclerosis Cholesterol Ischemia 40

Stroke Journal

JANUARY 21, 2024

Stroke, Volume 55, Issue 2 , Page 335-343, February 1, 2024. Reducing the high risk of recurrent stroke in patients with symptomatic intracranial atherosclerotic stenosis (sICAS) has proven to be challenging, but aggressive medical management, with intensive risk factor control and antithrombotic therapy, has been shown to be beneficial.

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Stroke Journal

JANUARY 21, 2024

Stroke, Volume 55, Issue 2 , Page 344-354, February 1, 2024. Intracranial atherosclerotic disease and resultant intracranial stenosis is a global leading cause of stroke, and poses an ongoing treatment challenge.

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Stenosis Risk Factors Technology Stroke 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP293-ATP293, February 1, 2025. The study was designed to investigate whether aortic arch types (AAT) was associated with the lateralization of subclavian artery stenosis (SAS).Methods:In vs 2.4%, p < 0.001) and (any degree stenosis: 8.4% vs 2.9%, p < 0.001).

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Stenosis Aortic Atherosclerosis Risk Factors 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP226-ATP226, February 1, 2025. Patients with extracranial vertebral artery (V1-2) 70% to 99% stenosis and transient ischemic attack or ischemic stroke within the past 3 months will be recruited (first patient enrollment: Sep 15, 2023).Results:A

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Stents Stent Stenosis Stroke 40

American College of Cardiology

OCTOBER 29, 2024

The goal of the PROTECTED TAVR trial was to evaluate the efficacy of intraprocedural cerebral embolic protection (CEP) in reducing strokes among patients undergoing transfemoral TAVR for aortic stenosis.

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Aortic valve Aortic TAVR Stroke 45

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP347-AWP347, February 1, 2025. Ischemic stroke, a heterogeneous disease with various etiological subtypes and risk factors, places stress on the BBB. To model stenosis, a microactuator was mounted on a 3D printed platform and connected to a capillary tube (~1 mm diameter).

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Stenosis Physiology Risk Factors Stroke 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP205-AWP205, February 1, 2025. CTAs were reviewed to assess the carotid stenosis and the anatomy of the aortic arch. Additionally, the severity of carotid stenosis in CEA-treated side was higher in patients with bovine arch compared to normal controls (82.5% [76.2-88.7] vs. 70.0% [50.0-95.0];

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Anatomy Stenosis Aortic Plaque 40

Journal of the American Heart Association

MARCH 13, 2025

BackgroundLp(a) (lipoprotein(a)) is an independent risk factor for calcific aortic valve stenosis (CAVS). Journal of the American Heart Association, Ahead of Print. Whether patients with CAVS and high Lp(a) levels are at higher risk of valvular or cardiovascular events is unknown. The maximal followup time was set to 5 years.

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Aortic valve Coronary Artery Bypass Graft Stenosis Aortic 45

Circulation: Cardiovascular Interventions

MARCH 26, 2025

BACKGROUND:Current guidelines recommend surgical aortic valve replacement (SAVR) for patients with severe aortic stenosis and unfavorable iliofemoral access. The primary outcome was a composite of death from any cause, stroke/transient ischemic attack, and procedure-related or valve-related hospitalization at 30 days and at 1 year.

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Aortic valve Aortic Stenosis TAVR 40

DAIC

MAY 15, 2024

In the meta-analysis of seven randomized trials, published in JSCAI and presented at the 2024 EuroPCR conference in Paris, France, researchers compared the outcomes of 7,785 patients undergoing TAVR (a procedure that delivers a new aortic valve into the heart through a catheter) to those undergoing SAVR for severe aortic stenosis.

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Aortic valve TAVR Outcomes Aortic 105

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP142-AWP142, February 1, 2024. Background:Intracranial atherosclerotic disease (ICAD) is associated with high recurrence rates of stroke despite aggressive medical management. Arterial segments extending from the stenosis to the MCA bifurcation were captured and quantified. mm2p=0.298).Conclusion:Area

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Stenosis Stroke Strokes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ADP36-ADP36, February 1, 2025. All patients had headache, and funduscopic examination demonstrated papilledema for all patients. All patients had headache, and funduscopic examination demonstrated papilledema for all patients.

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Stents Stent Stenosis Angioplasty 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP220-ATP220, February 1, 2024. The Tenzing was slowly inserted across the ICAD stenosis in each case under roadmap fluoroscopic guidance. Stenosis location was: 1 ICA, 7 M1, 4 M2, 2 vertebral. All patients were treated using the Tenzing 7 delivery catheter in an off-label fashion.

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Angioplasty Stenosis Stents Stent 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. IntroductionIntracranial atherosclerotic disease (ICAD) induces the luminal narrowing of an intracranial vessel and represents one of the major causes of ischemic strokes [1, 2, 3, 4].

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Stenosis Angioplasty Anatomy Plaque 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP276-AWP276, February 1, 2025. We aimed to investigate the association between VAH and atherosclerotic stenosis of subclavian artery (SA), vertebral artery (VA) and basilar artery (BA) based on digital subtraction angiography (DSA).Methods:In VAH and stenosis degree of the artery (i.e.,

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Stenosis Atherosclerosis Risk Factors Stroke 40

Open Heart

FEBRUARY 1, 2022

Objectives To investigate the reliability and agreement of hand-held ultrasound devices (HUDs) compared with conventional duplex ultrasound (HIGH) in examination for carotid stenosis in patients with suspected transitory ischaemic attack (TIA) or ischaemic stroke.

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Ultrasound Stenosis Stroke Strokes 52

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP116-AWMP116, February 1, 2024. Introduction:Medical treatment of internal carotid artery stenosis consists of treatment of underlying conditions such as hypertension, dyslipidemia, and diabetes mellitus, as well as antiplatelet therapy.

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Stenosis Aneurysm Diet Cholesterol 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page A38-A38, February 1, 2025. Background and Purpose:We aimed to investigate the effects of evolocumab, a proprotein convertase subtilisin/kexin type-9 inhibitor for intensive lipid-lowering, on intracranial atherosclerotic stenosis (ICAS).Methods:From 0.11] vs. evolocumab-: 0.02 [0.04-0.07]),

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Stenosis Plaque Outcomes Stroke 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP174-ATP174, February 1, 2024. The standardized mean difference (SMD) for post-procedure stenosis (%) was significantly lower (SMD: -0.52, 95% confidence interval [CI]: -0.79 The odds for post-procedure 30-day stroke and/or death were significantly lower (OR 0.68, 95% CI: 0.50-0.94,

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Stents Stent Stenosis Stroke 40