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Background Cardiogenic shock (CS) induced by severe aortic stenosis (AS) is a life-threatening condition with high mortality. Despite advancements in emergency interventions, the optimal treatment approach remains uncertain. The primary endpoint was mortality at 30 days. Results Seventeen studies were included, totalling 2811 patients.
The Neuroguard Integrated Embolic Protection (IEP) system is an experimental treatment for carotid artery stenosis, also known as carotid artery disease, a condition in which fatty-waxy deposits known as plaque builds up and blocks the normal flow of blood in the large arteries on either side of the neck.
About a fifth of all ischemic strokes are attributed to embolization of ruptured atherosclerotic plaque from carotid arterial stenosis. But it has been difficult to predict which person with asymptomatic carotid artery stenosis is likely to progress to symptomatic carotid disease and stroke. J Am Coll Cardiol.
Among patients with asymptomatic severe aortic stenosis, early TAVR was superior to clinical surveillance in reducing the incidence of death, stroke, or unplanned hospitalization for cardiovascular causes.
Objective The occurrence of ischemic stroke (IS) is closely related to the characteristics of carotid plaque (CP). Materials and methods This retrospective study evaluated 705 patients with low and intermediate carotid stenosis who underwent B-mode and CEUS from November 2021 to April 2023.
BackgroundThe utility of screening for the degree of common carotid artery (CCA) stenosis as a predictor of cardiovascular disease (CVD) in a general population remains unclear.Methods and ResultsWe studied 4775 Japanese men and women whose CCA was measured using bilateral carotid ultrasonography at baseline (April 1994–August 2001).
Background A quarter of patients with severe aortic stenosis (AS) were asymptomatic, and only a third of them survived at the end of 4 years. We noticed no difference in MI, stroke and major bleeding. We intended to study the effect of early AVR (eAVR) in this subset of asymptomatic patients with preserved left ventricle function.
The EARLY TAVR trial results demonstrate that early transcatheter aortic valve implantation in patients with asymptomatic severe aortic stenosis is superior to clinical surveillance in significantly reducing the composite primary outcome of death, stroke, or unplanned hospitalization for cardiovascular causes.
Stroke, Volume 55, Issue 2 , Page 355-365, February 1, 2024. This comprehensive literature review focuses on acute stroke related to intracranial atherosclerotic stenosis (ICAS), with an emphasis on ICAS-large vessel occlusion.
A review in The Lancet finds that 20% of the world population carries a genetic risk factor for cardiovascular diseases such as heart attacks, strokes, and aortic valve stenosis: Increased levels of a lipid particle called lipoprotein(a). It is the most common genetic cause of cardiovascular diseases.
Stroke, Volume 56, Issue Suppl_1 , Page ATMP57-ATMP57, February 1, 2025. Introduction:Literature demonstrates that nearly one-third of acute ischemic stroke (AIS) patients with large vessel occlusion (LVO) or severe stenosis arrive at the emergency room with mild symptoms, attributed to favourable collateral status.
Stroke, Volume 56, Issue 4 , Page e114-e118, April 1, 2025. Intracranial atherosclerotic stenosis is a leading cause of stroke with a significant risk of recurrent ischemic events despite aggressive medical management. However, 3 percutaneous angioplasty and stenting randomized trials showed negative or neutral results.
Stroke, Volume 56, Issue Suppl_1 , Page AWP286-AWP286, February 1, 2025. Background:Hemodynamic evaluation is crucial in assessing stroke risk in patients with symptomatic intracranial atherosclerotic stenosis (sICAS). Twenty patients (9.6%) experienced ischemic stroke or TIA during the one-year follow-up. before PTAS.
The goal of the PROTECTED TAVR trial was to evaluate the efficacy of intraprocedural cerebral embolic protection (CEP) in reducing strokes among patients undergoing transfemoral TAVR for aortic stenosis.
Stroke, Volume 55, Issue 2 , Page 311-323, February 1, 2024. Intracranial atherosclerotic disease (ICAD) is one of the most common causes of stroke worldwide. In addition to stroke, ICAD increases the risk of dementia and cognitive decline, magnifying ICAD societal burden.
Stroke, Volume 56, Issue Suppl_1 , Page A39-A39, February 1, 2025. Aggressive Medical Management for Preventing Recurrent Stroke in Intracranial Stenosis (SAMMPRIS) trial. Balloon expandable stent (BES) and self-expanding stent (SES) were used in 54 and 224 patients, respectively.
Transcatheter aortic valve implantation (TAVI) was superior to surgical aortic valve replacement for reducing death, stroke or rehospitalization in women with severe aortic stenosis, according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.
Stroke, Volume 56, Issue Suppl_1 , Page AWP16-AWP16, February 1, 2025. Introduction:Currently, no level A evidence exists for the optimal rescue strategy for cases at high risk for re-occlusion following endovascular thrombectomy (EVT) in acute ischemic stroke. Mean National Institute of Health Stroke Scale (NIHSS) on admission was 16.6;
Stroke, Ahead of Print. Asymptomatic high-grade carotid stenosis is an important therapeutic target for stroke prevention. Advances in treatments against atherosclerosis have driven down the rates of stroke in patients managed without revascularization.
In the meta-analysis of seven randomized trials, published in JSCAI and presented at the 2024 EuroPCR conference in Paris, France, researchers compared the outcomes of 7,785 patients undergoing TAVR (a procedure that delivers a new aortic valve into the heart through a catheter) to those undergoing SAVR for severe aortic stenosis.
However, its postoperative complications can have a significant effect on long-term patient outcomes. 33 preoperative clinical features and 4 postoperative complications were collected in each group.
Stroke, Volume 56, Issue Suppl_1 , Page ATP215-ATP215, February 1, 2025. Background:Carotid stenosis has been associated with stroke and cognitive impairment. It remains unclear if hypometablism, a marker for neurodegeneration, may be in the mechanistic pathway in the association between carotid stenosis and cognitive decline.
Stroke, Volume 56, Issue Suppl_1 , Page A41-A41, February 1, 2025. This is largely due to the Stenting and Aggressive Medical Management Therapy for Preventing Recurrent Stroke in Intracranial Arterial Stenosis (SAMMPRIS) trial results which featured a high periprocedural stroke rate.
Objectives To investigate the reliability and agreement of hand-held ultrasound devices (HUDs) compared with conventional duplex ultrasound (HIGH) in examination for carotid stenosis in patients with suspected transitory ischaemic attack (TIA) or ischaemic stroke.
Stroke, Volume 55, Issue Suppl_1 , Page AWP222-AWP222, February 1, 2024. Introduction:Moyamoya is a progressive cerebrovascular disease characterized by stenosis of the cerebral arteries in the anterior circulation and less often the posterior circulation. At time of diagnosis 16 children (67%) had basilar artery stenosis.
Stroke, Volume 56, Issue Suppl_1 , Page ATP219-ATP219, February 1, 2025. However, few reports have discussed CNs in the context of carotid artery stenosis. However, few reports have discussed CNs in the context of carotid artery stenosis. of patients with moderate to severe carotid artery stenosis who underwent CEA.
Stroke, Volume 55, Issue 2 , Page 324-334, February 1, 2024. Intracranial atherosclerotic stenosis is a prevalent cause of ischemic stroke worldwide. This review focuses on randomized secondary prevention trials involving antithrombotic therapy, endovascular treatment, open surgical therapy, and remote ischemic conditioning.
Stroke, Volume 56, Issue Suppl_1 , Page ATP226-ATP226, February 1, 2025. Patients with extracranial vertebral artery (V1-2) 70% to 99% stenosis and transient ischemic attack or ischemic stroke within the past 3 months will be recruited (first patient enrollment: Sep 15, 2023).Results:A
Stroke, Volume 56, Issue Suppl_1 , Page ATP318-ATP318, February 1, 2025. For this study, acute symptomatic was defined as hemispheric ischemic stroke or retinal ischemia ipsilateral to the carotid stenosis, with symptom onset within 24 hours of admission. Lipid-lowering therapies mitigate the risk of atherothrombotic events.
Stroke, Volume 55, Issue 2 , Page 344-354, February 1, 2024. Intracranial atherosclerotic disease and resultant intracranial stenosis is a global leading cause of stroke, and poses an ongoing treatment challenge.
Stroke, Volume 55, Issue 2 , Page 335-343, February 1, 2024. Reducing the high risk of recurrent stroke in patients with symptomatic intracranial atherosclerotic stenosis (sICAS) has proven to be challenging, but aggressive medical management, with intensive risk factor control and antithrombotic therapy, has been shown to be beneficial.
Stroke, Volume 55, Issue Suppl_1 , Page ATP299-ATP299, February 1, 2024. PR was calculated as the ratio of proximal to distal pressure at the stenosis site, indicating post-stenosis blood flow. Arterial stenosis severity was categorized using the WASIDMethod:50%-69% for moderate and 70%-99% for severe. PR > 0.76
Stroke, Volume 56, Issue Suppl_1 , Page ATP296-ATP296, February 1, 2025. Introduction:Nonstenotic carotid plaque is found in some patients with otherwise cryptogenic stroke (CS) but also in normal individuals and patients with stroke of known cause (KS). Methods of vessel imaging were carotid duplex ultrasound, CTA, and MRA.
Stroke, Volume 56, Issue Suppl_1 , Page ATP222-ATP222, February 1, 2025. Background:Symptomatic intracranial atherosclerotic disease carries a high stroke recurrence rate. Accurate prediction of stroke recurrence is critical for improving patient outcomes through timely and targeted interventions. Variables with p<0.05
Stroke, Volume 56, Issue Suppl_1 , Page AWP252-AWP252, February 1, 2025. Baseline angiograms were reviewed to assess the presence or absence of intracranial stenosis lesions (IS+ Vs IS-) different than the target occlusion. Bailout strategies were required more often in the IS+ group (34.6% minutes; p=0.018). Vs 3; p=0.036).Conclusions:Our
Stroke, Volume 56, Issue Suppl_1 , Page A71-A71, February 1, 2025. Background:The ideal timing of carotid artery stenting (CAS) in symptomatic internal carotid artery (ICA) stenosis is partly determined by the risk of stroke and/or death associated with timing of the procedure. for Days 31-180).
Stroke, Volume 56, Issue Suppl_1 , Page AWP347-AWP347, February 1, 2025. Ischemic stroke, a heterogeneous disease with various etiological subtypes and risk factors, places stress on the BBB. To model stenosis, a microactuator was mounted on a 3D printed platform and connected to a capillary tube (~1 mm diameter).
Stroke, Volume 56, Issue Suppl_1 , Page ATP293-ATP293, February 1, 2025. The study was designed to investigate whether aortic arch types (AAT) was associated with the lateralization of subclavian artery stenosis (SAS).Methods:In vs 2.4%, p < 0.001) and (any degree stenosis: 8.4% vs 2.9%, p < 0.001).
Interestingly, while rates of all-cause mortality did not differ significantly between PCI and CABG groups, PCI was associated with lower early stroke rates. Patients were stratified based on diabetes status, and various outcome measures were assessed using Kaplan-Meier event rates and Cox model hazard ratios.
Stroke, Volume 55, Issue Suppl_1 , Page AWP116-AWP116, February 1, 2024. Compared with contralateral carotid artery plaque, plaque burden at the ipsilateral carotid artery was much heavy, presented with a higher degree of stenosis, smaller lumen area (0.22±0.15 of them were male. 0.15), larger wall area (0.50±0.19
Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. IntroductionIntracranial atherosclerotic disease (ICAD) is associated with up to 32% of posterior circulation strokes.1 1 ICAD‐related strokes are at high risk for re‐occlusion following MT.
BACKGROUND:Current guidelines recommend surgical aortic valve replacement (SAVR) for patients with severe aortic stenosis and unfavorable iliofemoral access. The primary outcome was a composite of death from any cause, stroke/transient ischemic attack, and procedure-related or valve-related hospitalization at 30 days and at 1 year.
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