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Stenosis Related Topics 
Open Heart
MARCH 3, 2025
Background In congenital aortic stenosis (CAS), commissurotomy is an option in patients not suitable to receive a valve prosthesis. However, there is often a need for future additional interventions on the aortic valve. The fate of the aortic valve is, however, essentially unknown.
52 
Heart BMJ
FEBRUARY 26, 2025
A significant proportion of patients with severe aortic stenosis (AS) undergoing transcatheter aortic valve implantation (TAVI) have concomitant coronary artery disease (CAD). The best way to treat these patients is contentious.
JAMA Cardiology
OCTOBER 15, 2024
This narrative review analyzes associations among heart failure, aortic stenosis, and aortic valve replacement.
110 
JAMA Cardiology
FEBRUARY 11, 2025
This Viewpoint advocates for prompt aortic valve replacement (rather than clinical surveillance) as the default strategy for patients with asymptomatic severe aortic stenosis.
111 
JAMA Cardiology
APRIL 5, 2024
This cohort study explores whether a novel artificial intelligence (AI) video-based biomarker for aortic stenosis is associated with development and progression of aortic stenosis.
105 
Heart BMJ
FEBRUARY 26, 2025
The sociodemographic characteristics of patients undergoing intervention for aortic stenosis (AS) in England, and the impact of COVID-19, is unknown. Background Health inequalities in cardiovascular care have been identified in the UK.
52 
Open Heart
JANUARY 19, 2025
Background Cardiogenic shock (CS) induced by severe aortic stenosis (AS) is a life-threatening condition with high mortality. Despite advancements in emergency interventions, the optimal treatment approach remains uncertain.
Frontiers in Cardiovascular Medicine
JANUARY 22, 2025
Receiver operator characteristic curve (ROC) analysis indicated that CTFFR were effective in diagnosing impaired myocardial strain, particularly LS.ConclusionThere is a strong correlation between CTFFR, which is a functional measure for assessing coronary artery stenosis, and myocardial strain.
52 
Frontiers in Cardiovascular Medicine
MARCH 12, 2025
IntroductionPercutaneous balloon valvuloplasty is the treatment of choice for critical pulmonary valve stenosis (CPS) and pulmonary valve atresia with intact ventricular septum (PA/IVS) if the ventricle has a suitable size. The Z-scores of pulmonary valve diameter, balloon/annulus ratio, number of cusps, and persisting stenosis were analyzed.
52 
JAMA Cardiology
JULY 16, 2024
This meta-analysis evaluates lipoprotein(a) concentrations and hemodynamic progression in patients with aortic stenosis.
101 
DAIC
MARCH 25, 2024
The global, randomized trial ( envisiontrial.com ) will evaluate the safety and effectiveness of Abbott’s minimally invasive Navitor transcatheter aortic valve implantation (TAVI) system in approximately 1,500 patients at intermediate or low surgical risk with severe aortic stenosis (narrowing of the aortic valve). fall into this category.
115 
DAIC
APRIL 25, 2024
Aortic stenosis is a narrowing of the aortic valve which prevents the aortic leaflets from opening and closing properly. Patients with aortic stenosis often have heart murmurs and experience debilitating symptoms including chest pain, dizziness, fatigue, shortness of breath and an irregular heartbeat.
105 
Frontiers in Cardiovascular Medicine
JANUARY 23, 2025
The increased use of radiofrequency ablation (RFA) for atrial fibrillation (AF) has led to a rise in cases of pulmonary vein stenosis or occlusion (PVS/O) as a complication. While this occurrence was once rare, the growing number of patients undergoing this procedure has made it more prevalent.
DAIC
MARCH 28, 2024
milla1cf Thu, 03/28/2024 - 07:30 March 28, 2024 — Medtronic plc, a global leader in healthcare technology, announced that the United States Food and Drug Administration ( FDA ) has approved the Evolut FX+ transcatheter aortic valve replacement (TAVR) system for the treatment of symptomatic severe aortic stenosis. Aortic stenosis.
111 
HCPLive
OCTOBER 11, 2024
be overtreating aortic stenosis. Linda Gillam, MD, MPH, discusses the idea that the cardiology community may.
98 
Frontiers in Cardiovascular Medicine
JANUARY 20, 2025
BackgroundPatients who underwent surgical repair of supravalvular aortic stenosis (SVAS) are at high risk for postoperative major adverse cardiovascular events (MACE).
52 
DAIC
JANUARY 11, 2024
82-year-old man with calcified stenosis in left main artery who underwent coronary CTA by PCD CT. Curved multiplanar reformatted images at varying virtual monoenergetic imaging (VMI) levels (40-140 keV) show stenosis at each level. Percent diameter stenosis (PDS) decreased from 92.5% at 40 keV to 53.1% at 140 keV. at 140 keV.
105 
Cardiovascular Diabetology
MARCH 13, 2024
The association of the triglyceride-glucose (TyG) index with intracranial atherosclerotic stenosis (ICAS) and extracranial atherosclerotic stenosis (ECAS) is unclear. This study aimed to investigate the relati.
105 
Frontiers in Cardiovascular Medicine
FEBRUARY 17, 2025
IntroductionSince TAVR was approved for lower-risk aortic stenosis (AS) patients, managing post-implantation conduction disturbances has become crucial, especially with self-expanding heart valves (SEV).
52 
Journal of the American Heart Association
MARCH 13, 2025
BackgroundOur previous preclinical study demonstrated thatAPOE4targeted replacement mice exhibit more severe cerebral hypoperfusion and cognitive impairment thanAPOE3targeted replacement mice with carotid artery stenosis due to neurovascular dysfunction.
75 
The New England Journal of Medicine
JANUARY 15, 2025
Among patients with asymptomatic severe aortic stenosis, early TAVR was superior to clinical surveillance in reducing the incidence of death, stroke, or unplanned hospitalization for cardiovascular causes.
74 
American College of Cardiology
MAY 24, 2024
What is the relationship between aortic valve calcification (AVC) and aortic stenosis (AS) severity in patients with suspected low-flow low-gradient AS?
72 
Frontiers in Cardiovascular Medicine
MARCH 9, 2025
This study aimed to investigate the predictive value of RC and lipid ratios alone or in combination for the severity of coronary artery stenosis in patients with coronary heart disease (CHD).MethodsThe CHD patients were categorized into mild stenosis and moderate-to-severe stenosis groups.
52 
Medical Xpress - Cardiology
OCTOBER 29, 2024
Until now, patients with aortic stenosis—a narrowing of one of the heart's main valves—have had to wait until symptoms become severe before undergoing valve replacement.
80 
Journal of the American Heart Association
JANUARY 17, 2025
BackgroundPulmonary vein stenosis in children is associated with a poor prognosis. However, the cause and risk factors for mortality remain uncertain.MethodsThis retrospective, singlecenter study identified children with primary and secondary pulmonary vein stenosis through a cardiac catheterization database. 95% CI, 1.610.4];P=0.004),
76 
American College of Cardiology
FEBRUARY 21, 2024
Echocardiography remains the principal imaging modality for detection and diagnosis of aortic stenosis (AS), as well as for grading of severity.
75 Journal of the American Heart Association
DECEMBER 20, 2023
BackgroundThe utility of screening for the degree of common carotid artery (CCA) stenosis as a predictor of cardiovascular disease (CVD) in a general population remains unclear.Methods and ResultsWe studied 4775 Japanese men and women whose CCA was measured using bilateral carotid ultrasonography at baseline (April 1994–August 2001).
78 
Journal of the American Heart Association
JANUARY 19, 2024
BackgroundAortic valve calcium score is associated with hemodynamic severity of aortic stenosis. There was no correlation between MAC calcium score and mitral valve area (r=0.07;P=0.6) or mitral valve gradient (r=−0.03;P=0.8).ConclusionsMAC
American College of Cardiology
SEPTEMBER 27, 2024
How does diffuse interstitial myocardial fibrosis, as observed on cardiac magnetic resonance (CMR), correlate with clinical outcomes in moderate and asymptomatic severe aortic stenosis (AS)?
60 
Med Page Today
OCTOBER 28, 2024
(MedPage Today) -- Transcatheter aortic valve replacement (TAVR) yielded clinical benefit when given early in the disease process while patients still had no symptoms or other indication for aortic valve replacement, according to the EARLY TAVR.
105 American College of Cardiology
OCTOBER 28, 2024
The goal of the EARLY TAVR trial was to evaluate transcatheter aortic valve replacement (TAVR) compared with clinical surveillance among patients with asymptomatic severe aortic stenosis (stage C aortic stenosis).
63 
JAMA Cardiology
NOVEMBER 5, 2024
Aortic stenosis (AS) due to fibrosis and calcification of the aortic valve is a hazardous component of cardiovascular disease burden—after developing symptomatic AS, patients survive for an average of less than 2 years without treatment.
American College of Cardiology
SEPTEMBER 18, 2024
The goal of the AVATAR trial was to evaluate aortic valve replacement (AVR) compared with conservative therapy among patients with asymptomatic severe aortic stenosis.
64 
American College of Cardiology
FEBRUARY 26, 2025
In this weeks View, Dr. Eagle looks at the potential exposure-dependent protective effect of SGLT2 inhibitors on aortic valve stenosis progression.
63 
Frontiers in Cardiovascular Medicine
MARCH 20, 2025
ObjectivesRegistered, prospective, multicenter study of the short-term clinical outcomes of a novel transcatheter aortic valve system (Xcor system, Saint Medical Technology, Inc., Nanjing) to evaluate its safety and efficacy.Methods130 high risk patients with symptomatic severe AS from 11 institutions were treated with the novel Xcor system.
52 
Frontiers in Cardiovascular Medicine
FEBRUARY 23, 2024
This concept should be applied when managing older patients with severe aortic stenosis. Although left ventricular wall hypertrophy is expected in patients with aortic stenosis, it should not be assumed that this is caused only by aortic stenosis.
69 
The British Journal of Cardiology
MARCH 4, 2025
Coronary angiography identified moderate stenosis of the right coronary artery (RCA), without significant flow restriction by invasive pressure wire interrogation. The patient presented with recurrent palpitations and pre-syncope, with no chest pain.
73 
Med Page Today
JANUARY 16, 2025
(MedPage Today) -- People with transthyretin cardiac amyloidosis (ATTR-CA) on top of aortic stenosis (AS) fared particularly poorly in a large cohort study, which researchers said calls for awareness and timely treatment. Compared with AS alone.
59 
American College of Cardiology
FEBRUARY 18, 2025
The EARLY TAVR trial results demonstrate that early transcatheter aortic valve implantation in patients with asymptomatic severe aortic stenosis is superior to clinical surveillance in significantly reducing the composite primary outcome of death, stroke, or unplanned hospitalization for cardiovascular causes.
61 
Circulation
NOVEMBER 11, 2024
However, the most recurrent cardiac complication in RASopathies is pulmonary valve stenosis (PVS). This has motivated compassionate use of MEK inhibition (MEKi) for rare, but potentially lethal complications such as hypertrophic cardiomyopathy and lymphatic disease.
75 
Cassling
JANUARY 9, 2025
EchoSolv, the groundbreaking AI platform developed by Echo IQ, is revolutionizing the detection of aortic stenosis. With its unparalleled access to extensive echocardiographic data and AI-driven analysis, EchoSolv empowers clinicians to identify aortic stenosis earlier and with greater accuracy.
Heart BMJ
FEBRUARY 26, 2025
In the 22 years since Professor Alain Cribier performed the first transcatheter aortic valve implantation (TAVI) in Rouen in France, treatment pathways for patients with aortic valve stenosis have evolved rapidly.
59 
Frontiers in Cardiovascular Medicine
FEBRUARY 26, 2025
LVEF in patients of MIC-CHD was negatively correlated with the systolic stenosis degree of mural coronary artery (MCA) (r=0.6474, p=0.0123) and MIC length (r=0.5712, p=0.0414).ConclusionsThe
Open Heart
JANUARY 8, 2024
Background A quarter of patients with severe aortic stenosis (AS) were asymptomatic, and only a third of them survived at the end of 4 years. Only a select subset of these patients was recommended for aortic valve replacement (AVR) by the current American College of Cardiology/American Heart Association guidelines.
98
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