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ECG Cases 40 – Approach to Spontaneous Coronary Artery Dissection (SCAD)

ECG Cases

Jesse McLaren on when to consider Spontaneous Coronary Artery Dissection (SCAD), which patients are at risk for reocclusion, and the challenges of diagnosing SCAD in patients who have nonischemic ECGs despite silent occlusion, occlusions perfused by collaterals, or from non-occlusive MI on this ECG Cases.

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Polygenic Risk in Families With Spontaneous SCAD

American College of Cardiology

What is the contribution of rare and common genetic variants to spontaneous coronary artery dissection (SCAD)?

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Genetics architecture of spontaneous coronary artery dissection in an Italian cohort

Frontiers in Cardiovascular Medicine

Spontaneous coronary artery dissection (SCAD) is a relevant non-atherosclerotic cause of acute coronary syndrome with a complex genetic architecture. Recent discoveries have highlighted the potential role of miRNAs and protein-coding genes involved in the processing of small RNAs in the pathogenesis of SCAD.

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Spontaneous Coronary Artery Dissection: A Focus on Post-Dissection Care for the Vascular Medicine Clinician

Frontiers in Cardiovascular Medicine

Spontaneous coronary artery dissection (SCAD) is an uncommon condition which is increasingly recognized as a cause of significant morbidity. SCAD can cause acute coronary syndrome and myocardial infarction (MI), as well as sudden cardiac death. The standard of care for patients with SCAD is rapidly evolving.

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Spontaneous coronary artery dissection in women in the generative period: clinical characteristics, treatment, and outcome—a systematic review and meta-analysis

Frontiers in Cardiovascular Medicine

Introduction Spontaneous coronary artery dissection (SCAD) is a non-traumatic and non-iatrogenic separation of the coronary arterial wall. Results 14 studies with 2,145 females in the generative period with ACS caused by SCAD were analyzed. P-SCAD compared to NP-SCAD patients more frequently had STEMI (OR = 3.16; 95% CI: 2.30–4.34;

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Management and outcomes of spontaneous coronary artery dissection: a systematic review of the literature

Frontiers in Cardiovascular Medicine

Background Contemporary management of spontaneous coronary artery dissection (SCAD) is still controversial. Results The systematic review included 13 observational studies evaluating 1,801 patients with SCAD. Results The systematic review included 13 observational studies evaluating 1,801 patients with SCAD. Approximately 48.5%

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Spontaneous coronary artery dissection and fibromuscular dysplasia: insights into recent developments

Frontiers in Cardiovascular Medicine

Spontaneous coronary artery dissection (SCAD), an uncommon cause of acute coronary syndrome, continues to be a poorly understood disease predominantly affecting females. It is a concomitant disease found among SCAD patients. It is characterized by an abrupt separation in the coronary arterial wall due to intramural bleeding.

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