Journal of the American Heart Association

DECEMBER 12, 2023

BackgroundClinical practice guidelines for the management and convalescence of patients with spontaneous coronary artery dissection (SCAD) have yet to be developed. The awareness and detection of SCAD as a cardiac event was low among patients (35%) and perceived to be moderate among health care providers (55%). women; mean age, 53.2 years)

SCAD 81

SCAD Cardiac Rehabilitation Research Hospital 81

Frontiers in Cardiovascular Medicine

FEBRUARY 7, 2024

Introduction Spontaneous coronary artery dissection (SCAD) is a non-traumatic and non-iatrogenic separation of the coronary arterial wall. Results 14 studies with 2,145 females in the generative period with ACS caused by SCAD were analyzed. P-SCAD compared to NP-SCAD patients more frequently had STEMI (OR = 3.16; 95% CI: 2.30–4.34;

SCAD 64

SCAD STEMI Outcomes Risk Factors 64

Dr. Smith's ECG Blog

DECEMBER 7, 2023

The final diagnosis was spontaneous coronary artery dissection (SCAD) starting in the mid LAD and continuing distally where it wraps around the apex. SCAD wasn't on my differential per se , but in retrospect it should have been. Most patients presenting with SCAD report a preceding emotional or physical stressor. Buller, C.

SCAD 125

SCAD Ischemia Coronary Artery Disease Cardiomyopathy 125

Frontiers in Cardiovascular Medicine

FEBRUARY 11, 2025

BackgroundSpontaneous coronary artery dissection (SCAD) significantly contributes to myocardial infarction among young individuals. After excluding single nucleotide polymorphisms (SNPs) confounded by extrinsic variables, the association of neuroticism scores with SCAD susceptibility persisted.

SCAD 52

SCAD Myocardial Infarction Research 52

Frontiers in Cardiovascular Medicine

JUNE 3, 2024

Spontaneous coronary artery dissection (SCAD), an uncommon cause of acute coronary syndrome, continues to be a poorly understood disease predominantly affecting females. It is a concomitant disease found among SCAD patients. It is characterized by an abrupt separation in the coronary arterial wall due to intramural bleeding.

SCAD 52

SCAD Exercise Risk Factors Research 52

Frontiers in Cardiovascular Medicine

JANUARY 7, 2024

Introduction Differences in pathophysiology, clinical presentation, and natural course of ST-elevation myocardial infarction in female patients due to either spontaneous dissection (SCAD-STEMI) or atherothrombotic occlusion (type 1 STEMI) have been discussed. vs. 1.8 ± 5.1%, p  = 0.002). vs. 1.8 ± 5.1%, p  = 0.002).

Myocardial Infarction 59

Myocardial Infarction SCAD STEMI Thrombolysis 59

Coronary Artery Disease Journal

NOVEMBER 1, 2023

Background Spontaneous coronary artery dissection (SCAD) and Takotsubo syndrome (TTS) constitute two common causes of nonatherosclerotic acute cardiac syndrome particularly frequent in women. Results A total of 289 SCAD and 150 TTS patients were included; 89% were women. In-hospital events (43.3% vs. 7.1%, HR 5.3, vs. 9.6%, HR 4.5,

SCAD 52

SCAD Outcomes Risk Factors Atrial Fibrillation 52

Dr. Smith's ECG Blog

SEPTEMBER 25, 2024

Here is the post shock ECG: Cardiology was called stat for ischemic VT, query SCAD vs thrombotic occlusion vs coronary vasospasm. Cath lab was activated: There was no coronary artery disease, but there was spontaneous coronary artery dissection (SCAD) of the distal LAD, which was narrowed by 95%, and treated medically.

Chest Pain 67

Chest Pain Pericarditis SCAD STEMI 67

Dr. Smith's ECG Blog

OCTOBER 24, 2019

In the absence of these factors it is termed spontaneous coronary artery dissection ( SCAD ). At that time the literature suggested: SCAD was rare , Mostly related to pregnancy , Seen on angiography as a dissection flap , and Managed similarly to MI caused by CAD (ASA, BB, lytics/PCI ). The SCAD cases in Lobo et al. Lobo et al.

Chest Pain 52

Chest Pain SCAD STEMI Cardiogenic Shock 52

Dr. S. Venkatesan MD

DECEMBER 2, 2023

Spontaneous coronary dissection vs Iatrogenic dissection SCAD is a rare , different entity , enjoys a popular space in the patho-physiology of CAD. An important therapeutic caution is PCI is contraindicated in SCAD except in critical locations such as left main. Is plaque fissure painful ?

SCAD 52

SCAD Plaque Angina STEMI 52

Frontiers in Cardiovascular Medicine

DECEMBER 13, 2023

Methods 701 patients were divided into stable coronary artery disease (SCAD), ACS, and control groups. Results The lg (circSCMH1/miR-874) values of ACS, SCAD, and the control group decreased successively ( P  < 0.05). Then lg(circSCMH1/miR-874) was calculated and statistical analysis was performed.

Plaque 59

Plaque SCAD Coronary Artery Disease Myocardial Infarction 59

Journal of Cardiovascular Pharmacology

FEBRUARY 1, 2024

Short-chain acyl-CoA dehydrogenase (SCAD) negatively regulates pathological cardiac hypertrophy. The purpose of this study was to investigate the possible role of SCAD in cardiac fibrosis. Short-chain acyl-CoA dehydrogenase (SCAD) negatively regulates pathological cardiac hypertrophy.

SCAD 40

SCAD Heart Failure Hypertension Outcomes 40

Dr. Smith's ECG Blog

APRIL 8, 2022

Currently, SCAD is a diagnosis that can only be established emergently in the cath lab with angiography. Type 1 ACS OMI should be ruled out as it is the most common and most treatable cause, and only with angiography will type 1 ACS be ruled out and SCAD be diagnosed instead. And is there new left bundle branch block (LBBB)?

Chest Pain 52

Chest Pain SCAD STEMI Blog 52

Dr. Smith's ECG Blog

JULY 31, 2018

What is Spontaneous Coronary Artery Dissection (SCAD)? I asked Angie Lobo ( [link] ), a third year intermal medicine resident at Abbott Northwestern Hospital (and Minneapolis Heart Institute) and an aspiring cardiologist, to write a couple paragraphs on SCAD. There are no randomized controlled trials for treatment strategies in SCAD.

SCAD 52

SCAD Chest Pain Myocardial Infarction Ischemia 52

Dr. Smith's ECG Blog

SEPTEMBER 29, 2024

Relevance to Today's CASE: As per Dr. Smith — Trying to predict the "culprit" artery in today's case was confusing.

Cardiac Arrest 110

Cardiac Arrest STEMI Ischemia SCAD 110

Heart Sisters

AUGUST 4, 2024

"People often believe that their 'silent' heart attack is something else - like the flu or a pulled muscle. Much later, when they end up getting diagnosed with a heart attack that they didn't know they were having, they might recall an episode of feeling vaguely unwell." - Dr. Leslie Cho

Heart attacks 119

Heart attacks Heart Attack SCAD 119

Heart Sisters

SEPTEMBER 8, 2024

How many more cardiac studies do we need before we believe what decades of published cardiac research have already told us?

Research 129

Research SCAD 129

Dr. Anish Koka

MAY 16, 2023

MINOCA now encompasses Spontaneous Coronary Artery Dissection (SCAD), a rare condition that is known to manifest primarily in women and affects the epicardial coronary artery. Despite padding the MINOCA numbers with SCAD, MINOCA is much rarer than conventional epicardial coronary disease. Which is exactly what the numbers show.

Chest Pain 52

Chest Pain Coronary Artery Disease Cancer Heart attacks 52

ECG Cases

SEPTEMBER 10, 2024

On this month's EM Quick Hits podcast: Ian Chernoff on the often elusive diagnosis of traumatic coronary artery dissection, Anand Swaminathan on proper use of insulin in DKA and in hyperkalemia, Brit Long and Hans Rosenberg on mesenteric ischemia pearls and pitfalls in diagnosis and management, Dave Jerome on recognition and management exercise-associated (..)

Ischemia 107

Ischemia Exercise SCAD 107

Dr. Smith's ECG Blog

MAY 19, 2020

Spontaneous coronary artery dissection (SCAD) should be considered as a cause of MINOCA. Coronary microvascular dysfunction may contribute to MINOCA and requires further investigation. Coronary thrombosis or embolism can result in MINOCA, either with or without a hypercoagulable state.

Defibrillator 52

Defibrillator Circulation Plaque Cardiac Arrest 52

Frontiers in Cardiovascular Medicine

DECEMBER 18, 2023

Introduction Spontaneous coronary artery dissection (SCAD) accounts for 1%–4% of cases of acute coronary syndrome (ACS). SCAD is caused by separation occurring within or between any of the three tunics of the coronary artery wall. The incidence of SCAD is higher in women than in men, with a ratio of approximately 9:1.

SCAD 88

SCAD Genetic predisposition Risk Factors Chest Pain 88

Heart Sisters

SEPTEMBER 3, 2023

Two-thirds of clinical research on heart disease is still done on white middle-aged men. Will this new grant fund a solution to an alarming gender gap?

Heart Disease 52

Heart Disease Research Heart Attack Heart attacks 52

American College of Cardiology

JANUARY 31, 2024

In this week’s View, Dr. Eagle discusses the use of non–Vitamin-K antagonist oral anticoagulants versus warfarin across the spectrum of body mass index and weight.

SCAD 56

SCAD AFIB Article 56

Stroke Journal

FEBRUARY 1, 2024

Introduction:A recent regional study suggested an upward trend in the incidence rates of spontaneous cervical artery dissection (sCAD).

SCAD 40

SCAD Inpatient Stroke Strokes 40

Frontiers in Cardiovascular Medicine

FEBRUARY 5, 2024

Additional entities including spontaneous coronary artery dissection (SCAD), coronary microvascular disease (CMD), systemic autoimmune disorders, and mental and behavioral health will also be discussed in terms of their prevalence among women and their association with CVD.

Risk Factors 80

Risk Factors Cardiovascular Disease SCAD Diabetes 80

Frontiers in Cardiovascular Medicine

NOVEMBER 24, 2024

Spontaneous coronary artery dissection (SCAD) is a relevant non-atherosclerotic cause of acute coronary syndrome with a complex genetic architecture. Recent discoveries have highlighted the potential role of miRNAs and protein-coding genes involved in the processing of small RNAs in the pathogenesis of SCAD.

SCAD 59

SCAD 59

Dr. Smith's ECG Blog

DECEMBER 16, 2024

It was not SCAD (coronary dissection) Highest troponin I was 37,000 ng/L, but it was not measured to peak. Angiogram Door to balloon time was 120 minutes (much too long) because of time taken for a CT. Coronary angiogram showed 100% mid LAD occlusion for which she received a DES with excellent angiographic result.

Chest Pain 105

Chest Pain Aortic STEMI Ultrasound 105