Frontiers in Cardiovascular Medicine

JANUARY 3, 2024

Background Microcirculatory dysfunction is an independent risk factor for a poor prognosis after percutaneous coronary intervention (PCI) in patients with acute myocardial infarction (AMI). Cardiac function was measured by echocardiography during hospitalization and follow-up.

Myocardial Infarction 59

Myocardial Infarction Outcomes Cardiac Function Thrombolysis 59

Stroke Journal

FEBRUARY 1, 2024

Introduction:Although prior antiplatelet therapy (APT) could potentially contribute to bleeding risk, the influence of prior APT on intravenous thrombolysis outcomes remains controversial. Patients with prior APT were older (72 vs. 66 years), and had a higher prevalence of vascular risk factors than those without APT.

Stroke 40

Stroke Strokes Thrombolysis Hemorrhage 40

Stroke Journal

FEBRUARY 1, 2024

Background:Despite advances in intravenous thrombolysis and endovascular thrombectomy, numerous acute ischemic stroke survivors continue to experience various disability levels. Subgroup analyses revealed a noteworthy benefit of GTN in the 90-day NIHSS score for non-thrombolysis patients (1 vs 2, p=0.016).

Stroke 40

Stroke Strokes Thrombolysis Risk Factors 40

Frontiers in Cardiovascular Medicine

OCTOBER 10, 2024

Genetic protein S (PS) deficiency caused by PROS1 gene mutation is an important risk factor for hereditary thrombophilia.Case introductionIn this case, we report a 28-year-old male patient who developed a severe pulmonary embolism during his visit. The patient had experienced one month of chest pains, coughing and hemoptysis symptoms.

Embolism 40

Embolism Pulmonary Chest Pain Thrombosis 40

Stroke Journal

FEBRUARY 1, 2024

Outcomes included first pass effect (FPE, extended Thrombolysis in Cerebral Infarction [eTICI] 2c/3 after first pass) and favorable outcome (3-month modified Rankin Scale score of 0 to 2 or equal to premorbid mRS score).Results:Of Components of thrombi were quantified using immunostaining.

Atrial Fibrillation 40

Atrial Fibrillation Stroke Strokes Risk Factors 40

Stroke Journal

FEBRUARY 1, 2024

Hence, we aimed to study the pro-inflammatory and procoagulant responses post-thrombolysis and their contributory role in clinical outcome.Methods:This is a single-center retrospective study of ALT or TNK treated AIS patients admitted to a comprehensive stroke center over a 3-year period. A p-value of <0.05

Stroke 40

Stroke Strokes Thrombolysis Biomarkers 40

Stroke Journal

FEBRUARY 1, 2024

Background:Diabetes mellitus (DM) is one of the risk factors for acute ischemic stroke, usually leading to poor prognosis. While DM can reduce the effect of intravenous thrombolysis, metformin can have a positive outcome on AIS patients. Stroke, Volume 55, Issue Suppl_1 , Page AWP5-AWP5, February 1, 2024.

Diabetes 40

Diabetes Stroke Strokes Outcomes 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

There was no difference between the ALT and TNK cohorts in their baseline demographic characteristics or premorbid vascular risk factors. Of the 165 patients undergoing thrombolysis, 75 also underwent EVT, with 55 patients treated with ALT compared to 20 patients treated with TNK.

Thrombolysis 40

Thrombolysis Pharmacology Stroke Strokes 40

Stroke: Vascular and Interventional Neurology

AUGUST 16, 2023

Intravenous thrombolysis is a compelling therapeutic approach, with current limited data suggesting early intervention (4.5 This article provides a narrative review of pathophysiological features, risk factors, and current and emerging management techniques of CRAO. hours of symptom onset) results in better patient outcomes.

Article 40

Article Thrombolysis Ischemia Risk Factors 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 28, 2023

BACKGROUNDIn patients with acute ischemic stroke secondary to large vessel occlusion, achieving modified Thrombolysis in Cerebral Infarction (mTICI) 2c/3 (excellent recanalization) over mTICI 2b is associated with improved functional outcomes. Stroke: Vascular and Interventional Neurology, Ahead of Print.

Stroke 40

Stroke Strokes Thrombolysis Diabetes 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

IntroductionA high level of low‐density lipoprotein ‐ cholesterol (LDL‐C) is a known risk factor for ischemic stroke1. We collected data on baseline characteristics and demographics, functional outcomes at discharge and 90 days, and procedural information including final thrombolysis in cerebral infarction (TICI) grade.

Thrombolysis 40

Thrombolysis Outcomes Cholesterol Risk Factors 40

Dr. Smith's ECG Blog

DECEMBER 19, 2023

The commonest causes of MINOCA include: atherosclerotic causes such as plaque rupture or erosion with spontaneous thrombolysis, and non-atherosclerotic causes such as coronary vasospasm (sometimes called variant angina or Prinzmetal's angina), coronary embolism or thrombosis, possibly microvascular dysfunction.

Plaque 126

Plaque Angina Blog Stents 126

Stroke Journal

JANUARY 30, 2025

Introduction:Because of the risk of infarcted tissue leading to symptomatic intracerebral hemorrhage (sICH) after intravenous thrombolysis for acute ischemic stroke, patients are monitored for at least 24 hours in a critical care setting.

Thrombolysis 40

Thrombolysis Hemorrhage Stroke Strokes 40

DAIC

MAY 14, 2024

The new analysis of the trial results, led by UVA Health’s Andrew Southerland , MD, found that high blood sugar shortly after thrombolysis – opening blocked arteries in the brain with a clot-busting drug – was associated with greater risk for potentially deadly brain bleeds, particularly in older patients with more severe strokes.

Stroke 105

Stroke Strokes Thrombolysis Hemorrhage 105

Stroke Journal

JANUARY 30, 2025

There was no difference in the rate of administration of IV thrombolysis (5.0% Patients with CADASIL, in general, carried a lower burden of vascular risk factors. They received IV thrombolysis at an equal rate but EVT at a lower rate, likely due to the small vessel pathology of CADASIL. vs 49.8%, p=0.31), obesity (15.0%

Hospital 40

Hospital Stroke Strokes Thrombolysis 40

Open Heart

AUGUST 3, 2024

Methods In a prospective cohort study, patients with intermediate high-sensitivity cardiac troponin I concentrations (5 ng/L to sex-specific 99th percentile) in whom myocardial infarction was ruled out were enrolled and underwent coronary CT angiography (CCTA) after hospital discharge.

Coronary Artery Disease 52

Coronary Artery Disease Myocardial Infarction Chest Pain Thrombolysis 52

ADN Center of Excellence

OCTOBER 28, 2024

Some of the latest strategies include: Innovations in Thrombolysis and Clot Retrieval : Techniques such as tissue plasminogen activator (tPA) injections and mechanical thrombectomy are significantly improving recovery rates for ischemic stroke patients.

Stroke 59

Stroke Strokes Education Innovation 59

Stroke Journal

FEBRUARY 1, 2024

We fit logistic regression models adjusted for age, race/ethnicity, Charlson index, household income by ZIP code, administration of IV thrombolysis or thrombectomy (EVT), hospital teaching status, census region, and bedsize.Results:We included 434,463 IS discharges, of which 1,407 had APLS.

Inpatient 40

Inpatient Stroke Strokes Thrombolysis 40

Stroke Journal

NOVEMBER 9, 2023

Other risk factors remained unchanged. Intravenous thrombolysis and mechanical thrombectomy rates increased over time from 2008 to 2010 to 2017 to 2019 (9.5%–13.8% Secular trends for patient characteristics, treatments, and outcomes were analyzed.RESULTS:A total of 7050 eligible patients (mean age, 43.1; years (Ptrend=0.01).

Stroke 40

Stroke Strokes Outcomes Atrial Fibrillation 40

DAIC

FEBRUARY 7, 2024

Meschia is a pioneer in the study of inherited risk factors for ischemic stroke and has had a longstanding commitment to providing the latest evidence for carotid revascularization as a means for stroke prevention. Meschia is certified by the American Board of Psychiatry and Neurology (ABPN) in neurology and vascular neurology.

Stroke 105

Stroke Strokes Research Health Disparities 105

Dr. S. Venkatesan MD

MARCH 17, 2025

Why systemic hypertension is a weak coronary risk factor ? Unlike the brain, where stroke risk is directly related to systolic BP, fortunately sudden systolic spikes never get a chance to attack the coronary endothelium as much of the coronary lumen is closed during most periods of systole. of course at the cost of failure).

Angina 59

Angina Physiology Cardiomyopathy Aortic 59