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About a fifth of all ischemic strokes are attributed to embolization of ruptured atherosclerotic plaque from carotid arterial stenosis. But it has been difficult to predict which person with asymptomatic carotid artery stenosis is likely to progress to symptomatic carotid disease and stroke. J Am Coll Cardiol.
BackgroundThe utility of screening for the degree of common carotid artery (CCA) stenosis as a predictor of cardiovascular disease (CVD) in a general population remains unclear.Methods and ResultsWe studied 4775 Japanese men and women whose CCA was measured using bilateral carotid ultrasonography at baseline (April 1994–August 2001).
A review in The Lancet finds that 20% of the world population carries a genetic riskfactor for cardiovascular diseases such as heart attacks, strokes, and aortic valve stenosis: Increased levels of a lipid particle called lipoprotein(a). It is the most common genetic cause of cardiovascular diseases.
Stroke, Volume 55, Issue 2 , Page 355-365, February 1, 2024. This comprehensive literature review focuses on acute stroke related to intracranial atherosclerotic stenosis (ICAS), with an emphasis on ICAS-large vessel occlusion.
Stroke, Ahead of Print. Asymptomatic high-grade carotid stenosis is an important therapeutic target for stroke prevention. Advances in treatments against atherosclerosis have driven down the rates of stroke in patients managed without revascularization.
Stroke, Volume 55, Issue 2 , Page 344-354, February 1, 2024. Intracranial atherosclerotic disease and resultant intracranial stenosis is a global leading cause of stroke, and poses an ongoing treatment challenge.
Stroke, Volume 55, Issue 2 , Page 335-343, February 1, 2024. Reducing the high risk of recurrent stroke in patients with symptomatic intracranial atherosclerotic stenosis (sICAS) has proven to be challenging, but aggressive medical management, with intensive riskfactor control and antithrombotic therapy, has been shown to be beneficial.
Stroke, Volume 56, Issue Suppl_1 , Page ATP318-ATP318, February 1, 2025. Introduction:Elevated Low-Density-Lipoprotein Cholesterol (LDL-C) blood levels are a riskfactor for atherosclerosis. Lipid-lowering therapies mitigate the risk of atherothrombotic events. were asymptomatic and 40.2% acute symptomatic.
Stroke, Volume 56, Issue Suppl_1 , Page ATP293-ATP293, February 1, 2025. The study was designed to investigate whether aortic arch types (AAT) was associated with the lateralization of subclavian artery stenosis (SAS).Methods:In vs 2.4%, p < 0.001) and (any degree stenosis: 8.4% vs 2.9%, p < 0.001).
Stroke, Volume 56, Issue Suppl_1 , Page AWP347-AWP347, February 1, 2025. Ischemic stroke, a heterogeneous disease with various etiological subtypes and riskfactors, places stress on the BBB. Ischemic stroke, a heterogeneous disease with various etiological subtypes and riskfactors, places stress on the BBB.
BackgroundLp(a) (lipoprotein(a)) is an independent riskfactor for calcific aortic valve stenosis (CAVS). Whether patients with CAVS and high Lp(a) levels are at higher risk of valvular or cardiovascular events is unknown. Journal of the American Heart Association, Ahead of Print.
Stroke, Volume 56, Issue Suppl_1 , Page AWP276-AWP276, February 1, 2025. We aimed to investigate the association between VAH and atherosclerotic stenosis of subclavian artery (SA), vertebral artery (VA) and basilar artery (BA) based on digital subtraction angiography (DSA).Methods:In VAH and stenosis degree of the artery (i.e.,
Stroke, Volume 56, Issue Suppl_1 , Page ATP220-ATP220, February 1, 2025. Background:The uneven distribution of intracranial atherosclerotic stenosis (ICAS) along the internal carotid artery (ICA) had been described in early clinicopathological studies, yet related, large-scale data is lack despite the widespread utilization of angiography.
Stroke, Volume 56, Issue Suppl_1 , Page AWP56-AWP56, February 1, 2025. In this study, we evaluated the relationship between flossing and ICAS, defined as 50% stenosis. These results emphasize the importance of dental flossing in reducing the rates of CSVD and moderately severe ICAS, both known riskfactors for ischemic stroke.
Stroke, Volume 56, Issue Suppl_1 , Page ATP222-ATP222, February 1, 2025. Background:Symptomatic intracranial atherosclerotic disease carries a high stroke recurrence rate. Accurate prediction of stroke recurrence is critical for improving patient outcomes through timely and targeted interventions. Variables with p<0.05
Stroke, Volume 56, Issue Suppl_1 , Page AWP203-AWP203, February 1, 2025. Introduction:The middle cerebral artery (MCA) is the most common site for inrtacranial atherosclerotic stenosis. Demographic data, riskfactors and the history of ischemic stroke of all patients were recorded. 21.35), p<0.001).Conclusions:Both
Examples of cardio embolic stroke etiology include: 1. Atrial Fibrillation 2. Cardiomyopathy with mural thrombus 3. Patent Foramen Ovale 4. Severe calcific Aortic (valve) Stenosis 5. Mechanical prosthetic valve Severe carotid artery stenosis is also implicated in embolic stroke. But the ECG is Sinus!
These are true innovators who propose novel approaches to major research challenges in the areas of heart disease, stroke and brain health. Blood lipids such as cholesterol and triglycerides are causal riskfactors for coronary heart disease as well as several other types of cardiovascular disease , such as aortic stenosis).
Background:The optimal treatment in patients with severe aortic stenosis (AS) and small aortic annulus (SAA) remains to be determined. There were no differences between groups regarding mortality (TAVR: 1 [1.3%], SAVR: 1 [1.4%], p=1.00) and stroke (TAVR:0, SAVR: 2 [2.7%], p=0.24) at 30 days. Circulation, Ahead of Print.
Stroke, Volume 56, Issue Suppl_1 , Page A98-A98, February 1, 2025. Although MCAD can progress to MMD, the extent to which patients actually progress and the riskfactors for this progression have not been fully elucidated.Methods:We retrospectively reviewed patients with MCAD who underwentRNF213genotyping.
Stroke, Volume 55, Issue Suppl_1 , Page ATMP69-ATMP69, February 1, 2024. In a multivariable linear regression analysis,APOE4was an independent riskfactor for a worse ADAS-Cog delayed word recall score, indicating short-term memory impairment (β = 0.21, 95% confidence interval (CI) 0.026–2.30,p=
Stroke, Volume 56, Issue Suppl_1 , Page ATMP12-ATMP12, February 1, 2025. Background:Atherosclerotic carotid artery disease is associated with a high risk of major adverse cardiac events (MACE) even with optimal riskfactor management and surgical interventions such as carotid endarterectomy (CEA).
Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. It can occasionally present primarily with neurological conditions such as ischemic strokes, encephalopathy, or sensory neuropathy. His initial National Institutes of Health Stroke Scale was 3 for bilateral leg weakness.
Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. There is subsequent hypoperfusion of brain tissue, but thromboembolism and ischemic stroke is rare. There is subsequent hypoperfusion of brain tissue, but thromboembolism and ischemic stroke is rare.
Stroke-volume:50 ml. Even in patients whose moderate stenosis undergoes thrombosis, most angiograms show greater than 50% stenosis after the event. However, one can certainly imagine that many thromboses of non-obstructive lesions completely lyse and do not leave a stenosis on same day or next day angiogram.
At 3 and 6 months after ablation in patients with paroxysmal and non-paroxysmal AF, researchers did not observe any reported deaths or certain serious complications, including coronary spasm, persistent phrenic nerve palsy, atrio-esophageal fistula, or pulmonary vein stenosis. Lucas Boersma , electrophysiologist, St. doi:10.1001/jama.285.18.2370
Stroke, Volume 56, Issue Suppl_1 , Page ATMP98-ATMP98, February 1, 2025. Background:The secondary prevention of symptomatic intracranial atherosclerotic stenosis (sICAS) remains a significant challenge. These findings are preliminary and warrant further investigation through randomized controlled trials.
1 These included one pseudoaneurysm, one PV stenosis and one hematoma.1 Int J Stroke. Lifetime risk of atrial fibrillation according to optimal, borderline, or elevated levels of riskfactors: cohort study based on longitudinal data from the Framingham Heart Study. 2021 Feb;16(2):217-221. Circulation Research.
Stroke, Volume 56, Issue Suppl_1 , Page AWP351-AWP351, February 1, 2025. Collateral development plays an important role in maintaining cerebral blood flow (CBF) in the presence of critical stenosis or occlusion of large cerebral arteries. Age is a non-modifiable riskfactor for ischemic stroke associated with collateral rarefaction.
Stroke, Ahead of Print. CONCLUSIONS:Higher sdLDL-C was associated with an increased risk of incident carotid plaques, especially carotid plaques with vulnerable morphology, even in participants with normal LDL-C. Incident carotid plaques and their vulnerability were detected by carotid ultrasound at follow-up (2021). years (SD=0.14).
Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. IntroductionCarotid webs (CaW) have been increasingly recognized as a unique cause of recurrent ischemic strokes.1 The patient was admitted to the neurovascular intensive care unit and started on aspirin and high‐risk heparin drip.
Stroke: Vascular and Interventional Neurology, Ahead of Print. BACKGROUNDHypertension is often codiagnosed in patients with moyamoya disease (MMD), a progressive intracranial steno‐occlusive vasculopathy; this has principally been attributed to renal artery stenosis (up to 10%).
Stroke, Ahead of Print. The presence of stenosis/occlusion was graded radiographically to assess for disease progression and the prevalence of riskfactors related to reduced progression-free survival.RESULTS:In all, 686 patients met the inclusion criteria, with PCA disease identified in 282 (41.1%) patients.
24 will focus on the following three current guideline updates: American College of Cardiology (ACC)/American Heart Association (AHA) Guidelines 2023 Atrial Fibrillation Guideline - Pharmacology II: Strokes vs. Bleeds, What Do the Guidelines Tell Us About Practical Management in A-fib? The Guidelines Sessions at ACC.24
Here are the images from the cardiac cath: Mid to distal-LAD in-stent stenosis with 100% occlusion and TIMI flow 0 LAD post-DES placement with TIMI 3 flow The amount of territory supplied by this vessel becomes obvious here (and goes on for a few more frames below this still). Teaching points: 1.
Stroke, Volume 55, Issue Suppl_1 , Page AWP226-AWP226, February 1, 2024. Riskfactors and severity of disease progression in children with moyamoya and posterior cerebral artery (PCA) stenosis have not been well described in the literature. Children with moyamoya and PCA stenosis had a 3.5
Stroke, Volume 55, Issue Suppl_1 , Page AWP255-AWP255, February 1, 2024. Asymptomatic intracranial large artery stenosis (ILAS) has been associated with higher risk of stroke and dementia. Asymptomatic intracranial large artery stenosis (ILAS) has been associated with higher risk of stroke and dementia.
Stroke, Volume 55, Issue Suppl_1 , Page ATP221-ATP221, February 1, 2024. Background:Both intracranial artery stenosis (ICAS) and cerebral small vessel disease (CSVD) can cause heavy socioeconomic burdens. Incident ICAS was defined as new stenosis occurring in at least one artery or increased severity of the original artery stenosis.
Stroke, Volume 55, Issue Suppl_1 , Page AWP239-AWP239, February 1, 2024. Introduction:Apolipoprotein E4 (ApoE4) allele is linked to increased LDL-Cholesterol, one of the main riskfactors for intracranial large artery stenosis (ICAS). ApoE4 carrier status was associated with higher ICAS score among hypertensive men (B=0.52±0.11,
Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. IntroductionIntracranial atherosclerotic disease (ICAD) is one of the leading causes of ischemic stroke. Patients with ICAD more frequently presented with vascular riskfactors. CTA collaterals scores were comparable between groups.
Stroke, Volume 55, Issue Suppl_1 , Page AWP276-AWP276, February 1, 2024. Introduction:It is known that past the age of 35, the prevalence of large artery atherosclerosis (LAA) related strokes increases with a cardiovascular riskfactor (CVRF) profile beginning to resemble that of elderly patients. vs. 38.2 ± 8.0
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