Medical Xpress - Cardiology

SEPTEMBER 13, 2024

A review in The Lancet finds that 20% of the world population carries a genetic risk factor for cardiovascular diseases such as heart attacks, strokes, and aortic valve stenosis: Increased levels of a lipid particle called lipoprotein(a). It is the most common genetic cause of cardiovascular diseases.

Aortic valve 86

Aortic valve Heart Disease Heart Attack Heart attacks 86

Frontiers in Cardiovascular Medicine

APRIL 24, 2024

With this longer lifespan, calcific aortic stenosis (AS) was identified as an emerging critical risk factor for cardiac death in older patients. Three were successful and 1 patient died perioperatively due to cardiovascular disease severity, highlighting the importance of intervention timing and comparative risk stratification.

Stenosis 52

Stenosis Aortic Peripheral Arterial Disease TAVR 52

Stroke Journal

JUNE 26, 2024

Asymptomatic high-grade carotid stenosis is an important therapeutic target for stroke prevention. Transcarotid artery revascularization has a favorable periprocedural risk profile, but randomized trials comparing it to intensive medical management are lacking.

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Stenosis Stents Stent Atherosclerosis 40

Frontiers in Cardiovascular Medicine

AUGUST 7, 2024

Aortic Stenosis (AS) is a common condition with an estimated pooled prevalence of all AS in the elderly population at around 12.4%, with that of severe AS estimated to be around 3.4%. In the past, surgical aortic valve replacement was the primary treatment option for severe AS for decades.

Aortic valve 98

Aortic valve Aortic TAVR Peripheral Arterial Disease 98

Stroke Journal

JANUARY 21, 2024

Intracranial atherosclerotic disease and resultant intracranial stenosis is a global leading cause of stroke, and poses an ongoing treatment challenge. Among patients with intracranial stenosis, those with hemodynamic compromise are at high risk for recurrent stroke despite medical therapy and risk factor modification.

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Stenosis Risk Factors Technology Stroke 40

Frontiers in Cardiovascular Medicine

AUGUST 2, 2024

Percutaneous coronary intervention (PCI), as a relatively rapid and effective minimally invasive treatment for coronary heart disease (CHD), can effectively relieve coronary artery stenosis and restore myocardial perfusion. However, the occurrence of major adverse cardiovascular events (MACE) is a significant challenge for post PCI care.

Biomarkers 96

Biomarkers Risk Factors Stenosis Heart Disease 96

Stroke Journal

JANUARY 21, 2024

Reducing the high risk of recurrent stroke in patients with symptomatic intracranial atherosclerotic stenosis (sICAS) has proven to be challenging, but aggressive medical management, with intensive risk factor control and antithrombotic therapy, has been shown to be beneficial.

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Stenosis Blood Pressure Diet Risk Factors 40

Circulation

NOVEMBER 11, 2024

However, the long-term outcomes in patient with an intermediate stenosis received FFR have not yet been investigated comprehensively.Methods:We retrospective included 558 patients underwent both coronary artery angiography (CAG) and FFR.

Coronary Artery Disease 40

Coronary Artery Disease Stenosis Risk Factors Outcomes 40

JAMA Cardiology

NOVEMBER 5, 2024

Aortic stenosis (AS) due to fibrosis and calcification of the aortic valve is a hazardous component of cardiovascular disease burden—after developing symptomatic AS, patients survive for an average of less than 2 years without treatment.

Atherosclerosis 40

Atherosclerosis Aortic Stenosis Aortic valve 40

DAIC

MARCH 6, 2024

The CAD Staging System is a noninvasive imaging-based investigational software device that analyzes important and actionable features of coronary atherosclerosis, stenosis and ischemia. Food and Drug Administration ( FDA ) for its Coronary Artery Disease ( CAD ) Staging System.

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Heart Disease Heart Attack Heart attacks Technology 105

Ken Grauer, MD

FEBRUARY 3, 2024

BUT — Cardiac catheterization done a little later did not reveal any significant stenosis. Despite the absence of significant coronary stenosis on her post-arrest cath — the ECG in Figure-1 is clearly diagnostic of an extensive anterolateral STEMI ( presumably from acute LAD [ L eft A nterior D escending ] coronary artery occlusion).

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Blog Cardiac Arrest STEMI Plaque 164

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Nontraditional lipid variables including triglycerides/high‐density lipoprotein cholesterol (HDL‐C) ratio and total cholesterol/HDL‐C ratio are linked to a vascular risk as a residual risk factor. ICAS was defined as >/=50% stenosis and quantified by presence, >/=2, and >/=3.

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Stenosis Cholesterol Stroke Strokes 40

Frontiers in Cardiovascular Medicine

DECEMBER 14, 2023

This study aimed to investigate the association between various complex indexes of blood cell types and lipid levels with the severity of coronary artery stenosis and their predictive value in coronary heart disease (CHD). Results It revealed a positive correlation between all complex indexes and the severity of coronary artery stenosis.

Heart Disease 64

Heart Disease Cholesterol Stenosis Atherosclerosis 64

Frontiers in Cardiovascular Medicine

APRIL 7, 2024

Transcatheter aortic valve replacement (TAVR) has increasingly become a safe, feasible, and widely accepted alternative surgical treatment for patients with severe symptomatic aortic stenosis.

Aortic valve 52

Aortic valve Aortic TAVR Risk Factors 52

The British Journal of Cardiology

AUGUST 1, 2024

Genome-wide association and Mendelian randomisation studies have identified lipoprotein(a) (Lp[a]) as an emerging risk factor for calcific aortic stenosis and a causal risk factor for atherosclerotic cardiovascular disease (ASCVD) in different ethnicities.

Risk Factors 40

Risk Factors Atherosclerosis Laboratory Stenosis 40

Frontiers in Cardiovascular Medicine

DECEMBER 13, 2023

Transcatheter aortic valve replacement (TAVR) is a relatively new treatment method for aortic stenosis (AS) and has been demonstrated to be suitable for patients with varying risk levels.

Aortic valve 64

Aortic valve Cardiac Rehabilitation Aortic TAVR 64

Stroke Journal

FEBRUARY 1, 2024

In a multivariable linear regression analysis,APOE4was an independent risk factor for a worse ADAS-Cog delayed word recall score, indicating short-term memory impairment (β = 0.21, 95% confidence interval (CI) 0.026–2.30,p=

Stenosis 40

Stenosis Risk Factors Circulation Stroke 40

Dr. Smith's ECG Blog

MAY 20, 2024

Or is it a very tight stenosis that does not allow enough flow to perfuse myocardium that has a high oxygen demand from severely elevated BP? However, in light of risk factors for atherosclerotic disease and dynamic EKG changes today, we will pursue a CTCA tomorrow for further evaluation of coronaries.

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Chest Pain Blood Pressure Ischemia STEMI 129

DAIC

JANUARY 22, 2024

Blood lipids such as cholesterol and triglycerides are causal risk factors for coronary heart disease as well as several other types of cardiovascular disease , such as aortic stenosis). While some genes have been associated with the risk of developing AAA disease, none is thought to cause an AAA by itself.

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Heart Disease Research Aneurysm Cardiovascular Disease 105

Cardiometabolic Health Congress

NOVEMBER 14, 2024

42% of adults are considered obese , increasing their risk of diabetes, hypertension, and cardiovascular issues. Additionally, 10% of the global population suffers from chronic kidney disease , with diabetes and hypertension as significant risk factors. In the U.S.,

CME 103

CME Obesity Heart Failure Biomarkers 103

Circulation

OCTOBER 25, 2023

Background:The optimal treatment in patients with severe aortic stenosis (AS) and small aortic annulus (SAA) remains to be determined. Circulation, Ahead of Print.

Aortic valve 40

Aortic valve Aortic TAVR Stenosis 40

The British Journal of Cardiology

AUGUST 1, 2024

Lipoprotein(a) (Lp[a]) can improve the accuracy of assessment of atherosclerotic cardiovascular disease and the risk of aortic valve stenosis. Management of high levels encourages rigorous attention to correction of other risk factors, such as blood pressure, smoking and low-density lipoprotein (LDL).

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Aortic valve Heart Disease Blood Pressure Risk Factors 40

Circulation

NOVEMBER 11, 2024

Conclusion:Patients with 22q11 deletion syndrome are more likely to have reduced LPA to RPA ratio and need intervention on the LPA at the initial surgery, despite Tetralogy of Fallot (the only of the three lesions known to be associated with LPA stenosis) being over represented in the control group.

Pulmonary 40

Pulmonary Risk Factors Heart Disease Echocardiogram 40

DAIC

MARCH 28, 2024

The primary safety endpoint was incidence of early onset (within seven days) primary adverse events; atrio-esophageal fistula (within 90 days); cardiac tamponade or perforation (within 30 days); and PV stenosis (within 12 months). Circulation Research. 2020 June;127(1):4-20. doi: 10.1161/CIRCRESAHA.120.316340 120.316340 4 Staerk, et al.

Atrial Fibrillation 110

Atrial Fibrillation AFIB Ablation Pulmonary 110

All About Cardiovascular System and Disorders

NOVEMBER 11, 2023

SCAPE is an acronym for sympathetic crash acute pulmonary edema, which can typcially occur in Pickering syndrome with renal artery stenosis [1]. Another term for transient acute pulmonary edema which occurs in renal artery stenosis is flash pulmonary edema.

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Pulmonary Stenosis Blood Pressure Risk Factors 52

DAIC

JANUARY 25, 2024

Coronary computed tomography angiography (CCTA) is routinely used to diagnose CAD caused by the narrowing (stenosis) or blockage of the coronary arteries that supply the heart with blood. More than 8 million Americans visit hospital emergency departments experiencing chest pain every year.

Heart Attack 110

Heart Attack Heart attacks Technology Cardiovascular Disease 110

Frontiers in Cardiovascular Medicine

FEBRUARY 7, 2024

FAI was still associated with global CFR after adjusting for traditional risk factors (age, hypertension, diabetes, hyperlipidemia, and smoking). Altogether, FAI can help reveal microcirculatory damage in patients who do not exhibit epicardial artery stenosis.

Coronary Artery Disease 64

Coronary Artery Disease Atherosclerosis Plaque Risk Factors 64

Open Heart

SEPTEMBER 14, 2022

VHD incidence was determined using International Classification of Disease-10 codes for aortic stenosis (AS), aortic regurgitation (AR), mitral stenosis, mitral regurgitation (MR) and mitral valve prolapse. In our adjusted model, aortic and mitral VHD had an increased risk of all-cause death compared with no VHD (HR 1.62, 95% CI 1.44

Coronary Artery Disease 52

Coronary Artery Disease Bicuspid/Mitral Atrial Fibrillation Aortic 52

Frontiers in Cardiovascular Medicine

MAY 21, 2024

Doppler ultrasonography performed a day after the operation showed an increase in systolic blood velocity, with no observed urine output and raising a suspicion of arterial anastomotic stenosis. The transplant renal artery lesion was intervened with a stent.

Transplant 52

Transplant Ultrasound Atherosclerosis Plaque 52

EMS 12-Lead

AUGUST 25, 2024

Examples of cardio embolic stroke etiology include: 1. Atrial Fibrillation 2. Cardiomyopathy with mural thrombus 3. Patent Foramen Ovale 4. Severe calcific Aortic (valve) Stenosis 5. Mechanical prosthetic valve Severe carotid artery stenosis is also implicated in embolic stroke.

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AFIB Embolism Atrial Fibrillation RN 59

Open Heart

FEBRUARY 1, 2022

years; 1261 (66.6%) women) who presented with chest pain and non-obstructive CAD (angiographic stenosis <50%); coronary vasoreactivity was assessed in the mid-left anterior descending artery. Furthermore, among patients with low aortic PP, CMEID was an independent risk factor for all-cause mortality (HR 2.04, 95% CI 1.01

Coronary Artery Disease 52

Coronary Artery Disease Aortic Chest Pain Risk Factors 52

Dr. Smith's ECG Blog

NOVEMBER 15, 2023

Even in patients whose moderate stenosis undergoes thrombosis, most angiograms show greater than 50% stenosis after the event. However, one can certainly imagine that many thromboses of non-obstructive lesions completely lyse and do not leave a stenosis on same day or next day angiogram.

Coronary Angiogram 108

Coronary Angiogram Plaque Thrombosis STEMI 108

Circulation

JANUARY 15, 2024

Limited spatial resolution and blooming artifacts may hinder estimation of degree of coronary artery stenosis. Nevertheless, the relationship between CAC and the susceptibility of a plaque to provoke a thrombotic event remains incompletely understood. However, contemporary computed tomography cannot assess early microcalcification.

Coronary Artery Disease 45

Coronary Artery Disease Atherosclerosis Laboratory Plaque 45

Journal of the American Heart Association

FEBRUARY 23, 2024

BackgroundChronic inflammatory disease (CID) accelerates atherosclerosis and the development of aortic stenosis. The presence of CID was associated with a higher rate of postinterventional infection (5% versus 1%,P=0.007) and further emerged as a risk factor for rehospitalization for bleeding or infection (hazard ratio, 1.93

Aortic valve 49

Aortic valve Aortic Outcomes Atrial Fibrillation 49

Heart BMJ

JANUARY 29, 2024

Objectives Lipoprotein(a) (Lp(a)) is associated with an increased incidence of native aortic stenosis, which shares similar pathological mechanisms with bioprosthetic aortic valve (bAV) degeneration. p=0.001) and multivariable analysis adjusted by other risk factors for bioprostheses degeneration (HR 4.4, 95% CI 1.7 95% CI 1.9

Aortic valve 52

Aortic valve Aortic Risk Factors Stenosis 52

DAIC

MAY 18, 2024

At 3 and 6 months after ablation in patients with paroxysmal and non-paroxysmal AF, researchers did not observe any reported deaths or certain serious complications, including coronary spasm, persistent phrenic nerve palsy, atrio-esophageal fistula, or pulmonary vein stenosis. Lucas Boersma , electrophysiologist, St. doi:10.1001/jama.285.18.2370

Atrial Fibrillation 105

Atrial Fibrillation Heart Rhythm Ablation Quality of Life 105

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

However, CTA head and neck 4 days later demonstrated 90 percent stenosis of the mid left V2 at the C3‐4 level and a 75‐90 percent stenosis of the left mid V2 segment at the C5‐6 level (hard and soft plaque in these areas). He also had moderate stenosis of the right V4 segment.

Stenosis 40

Stenosis Peripheral Arterial Disease Pacemaker Atherosclerosis 40