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Prospective Multicenter International Registry of Ultrasound-Facilitated Catheter-Directed Thrombolysis in Intermediate-High and High-Risk Pulmonary Embolism (KNOCOUT PE)

Circulation: Cardiovascular Interventions

BACKGROUND:Prior clinical trials have demonstrated the efficacy of ultrasound-facilitated catheter-directed thrombolysis (USCDT) for the treatment of acute intermediate-risk pulmonary embolism (PE) using reduced thrombolytic doses and shorter infusion durations. Circulation: Cardiovascular Interventions, Ahead of Print. mg, with 31.0%

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Abstract TP190: Intracerebral Hemorrhage Laterality and Associations with Mood and Quality of Life Outcomes: A MISTIE III Substudy

Stroke Journal

Prespecified outcomes included modified Rankin scale (mRS) scores, EuroQol Visual Analogue Scale (EQ-VAS), and EQ-5D 3 level version (EQ-5D-3L, composite and individual components) at 30, 180, and 365 days post-ICH.

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Abstract TP115: Differences in the Medical Management of Post-Stroke Sequelae Among Patients Treated with Mechanical Thrombectomy vs Intravenous Thrombolysis

Stroke Journal

Background:Mechanical thrombectomy (MT) as treatment for acute ischemic stroke (AIS) has demonstrated superior functional outcomes compared to intravenous thrombolysis (IVT). Healthcare providers should screen for these post-stroke sequelae, which substantially affect quality of life for AIS survivors.

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Abstract WP13: Derivation and Validation of Utility Weights for the Modified Rankin Scale From the AcT Thrombolysis Trial

Stroke Journal

Quality of life at 90 days post-randomization was assessed using EQ-5D-5L. This study aims to derive utility weights for UW-mRS by directly mapping 5-item EuroQoL (EQ-5D-5L) responses to mRS scores.Methods:Data were collected from all patients included in Alteplase compared to Tenecteplase (AcT) trial.

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Abstract HUP15: Combined Measures of Socioeconomic Status Associated with Cognitive Symptoms Following Acute Ischemic Stroke

Stroke Journal

Introduction:Late complications after stroke (LCAS), including cognitive symptoms, impact quality of life and recovery. Stroke, Volume 56, Issue Suppl_1 , Page AHUP15-AHUP15, February 1, 2025. It is not known if neighborhood-level measures of socioeconomic status (SES) influence LCAS.

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Abstract HUP1: Drivers of Disparities in Stroke Outcomes by Neighborhood Socioeconomic Status: A Causal Mediation Analysis

Stroke Journal

90-day outcomes were functional status via the average of the 22-item ADL/IADL Scale, post-stroke depression symptoms via the PHQ-8, and quality-of-life via the average of the Stroke Specific QoL Scale (SS-QOL). The census-derived nSES index was our exposure.

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Abstract DP53: Drivers of Disparities in Stroke Outcomes by Neighborhood Socioeconomic Status: A Causal Mediation Analysis

Stroke Journal

90-day outcomes were functional status via the average of the 22-item ADL/IADL Scale, post-stroke depression symptoms via the PHQ-8, and quality-of-life via the average of the Stroke Specific QoL Scale (SS-QOL). The census-derived nSES index was our exposure.

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