Med Page Today

MARCH 27, 2024

(MedPage Today) -- The FDA approved sotatercept (Winrevair) for treating pulmonary arterial hypertension (PAH) in adults, Merck announced on Tuesday. A novel activin signaling inhibitor, sotatercept is indicated to increase exercise capacity.

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Pulmonary Hypertension Exercise 140

Science Daily - Heart Disease

AUGUST 21, 2024

A new study has found that asporin, a protein encoded by the ASPN gene, plays a protective role in pulmonary arterial hypertension (PAH).

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Pulmonary Hypertension 103

Society of Thoracic Surgeons - Surgeon

OCTOBER 16, 2024

Resource Pulmonary Resection for Lung Cancer Risk Calculator gmckinney Wed, 10/16/2024 - 07:59 The new pulmonary resection for lung cancer risk calculator is engineered using contemporary data from the STS General Thoracic Surgery Database.

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Cancer Pulmonary Hospital Outcomes 52

DAIC

MAY 8, 2024

Bioelectronic medicine scientists at The Feinstein Institutes for Medical Research used noninvasive, splenic focused ultrasound stimulation (sFUS) and found they can reduce inflammation and improve symptoms of pulmonary arterial hypertension (PAH). The research team delivered sFUS to cohorts of preclinical models with the disease.

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Ultrasound Pulmonary Research Hypertension 115

Journal of Clinical Investigation - Cardiology

FEBRUARY 1, 2024

Pulmonary arterial hypertension (PAH) is a devastating and progressive disease with limited treatment options. Endothelial haploinsufficiency of RAB7 caused spontaneous pulmonary hypertension (PH) in mice. Here, we explored the role of RAB7 in endothelial cell (EC) function and lung vascular homeostasis.

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Pulmonary Hypertension 98

Medical Xpress - Cardiology

MAY 19, 2024

The use of hormone replacement therapy (HRT) may be associated with improved pulmonary hypertension in women, according to research presented at the ATS 2024 International Conference held May 17–22 in San Diego.

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Pulmonary Hypertension Research 85

Frontiers in Cardiovascular Medicine

NOVEMBER 17, 2024

BackgroundAllergy to iodine contrast agents has long been a contraindication for balloon pulmonary angioplasty (BPA). The second BPA procedure was successfully performed using the fusion of previous pulmonary artery CTA images and real-time fluoroscopy images.

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Angioplasty Pulmonary Technology Hypertension 52

Heart BMJ

AUGUST 26, 2024

Background Decreased diffusing capacity of the lungs for carbon monoxide (DLco) is associated with microvascular damage in chronic thromboembolic pulmonary hypertension (CTEPH). The LD group had a shorter 6-minute walking distance (324±91 vs 427±114 m) than the ND group but the mean pulmonary artery pressure (mPAP) was similar (38.9±7.3

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Angioplasty Pulmonary Exercise Hypertension 52

HeartRhythm

NOVEMBER 4, 2024

Infants with severe valvar pulmonary stenosis (PS) are palliated by transcatheter balloon pulmonary valvuloplasty or surgical pulmonary valvotomy. Either strategy effectively relieves the obstruction, but one long-term sequela is pulmonary regurgitation (PR) necessitating pulmonary valve replacement.

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Pulmonary Stenosis Electrophysiology 40

DAIC

FEBRUARY 27, 2024

milla1cf Tue, 02/27/2024 - 17:29 February 27, 2024 — Aria CV, Inc , a developer of medical devices treating pulmonary hypertension, today announced the first patient was implanted with the Gen 2 Aria CV Pulmonary Hypertension System as part of the ASPIRE PH clinical trial at Ascension St. Ashwin Ravichandran and Scott Hittinger.

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Pulmonary Hypertension Heart Failure Blood Pressure 110

Heart BMJ

AUGUST 26, 2024

LEARNING OBJECTIVES Review the diagnostic pathway for pulmonary arterial hypertension (PAH) in congenital heart disease (CHD). Understand and interpret right heart catheterisation data in pulmonary hypertension related to CHD. Recognise the typical presentation of PAH in patients with CHD. Explore the treatment options for PAH-CHD.

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Congenital Heart Disease Congenital Pulmonary Hypertension 52

Journal of Cardiothoracic Surgery

AUGUST 20, 2024

This research evaluates the effect of balloon pulmonary angioplasty (BPA) on cardiac electrophysiological changes in patients with chronic thromboembolic pulmonary hypertension (CTEPH).

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Angioplasty Pulmonary Hypertension Electrophysiology 52

Journal of Cardiothoracic Surgery

MAY 13, 2024

Pulmonary arterial sarcomas (PAS) are rare aggressive tumours occurring mainly in the pulmonary trunk. We report a case of PAS involving the pulmonary trunk wall and valve, with uniform wall thickening which r.

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Pulmonary 52

DAIC

JULY 10, 2024

“This latest patent further secures the broad therapeutic potential of brilaroxazine for inflammatory conditions driven by underlying disruption in serotonin signaling like pulmonary hypertension,” said Laxminarayan Bhat, Ph.D. Founder, President, and CEO. Brilaroxazine has already received Orphan Drug Designation by the U.S.

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Pulmonary Hypertension Pharmacology Biomarkers 111

Med Page Today

JANUARY 1, 2024

(MedPage Today) -- Mortality rates were high among patients with high-risk pulmonary embolism (PE), with the worst outcomes in those with hemodynamic collapse, according to a retrospective analysis of the Pulmonary Embolism Response Team (PERT.

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Embolism Pulmonary Hospital Outcomes 119

Circulation

NOVEMBER 11, 2024

Rationale:Pulmonary arterial hypertension (PAH) is a devastating disease characterized by a progressive rise in pulmonary vascular resistance and occlusive vascular remodeling, leading to right heart failure and premature death. Endothelial cell (EC) damage and dysfunction is a key feature of pulmonary vascular remodeling and PAH.

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Pulmonary Hypertension Heart Failure Circulation 40

Becker's Hospital Review - Cardiology

OCTOBER 31, 2024

"CMS has proposed coverage of implantable pulmonary artery pressure sensors for heart failure management. Learn about the criteria and public comment period."

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CMS Pulmonary Heart Failure 52

ECG Guru

JULY 14, 2023

These are typical ECG changes that may indicate a pulmonary embolism. The patient has an acute pulmonary embolism. Sinus tachycardia may be present in acute pulmonary embolism. We see a sinus rhythm with left anterior fascicular block (LAFB) and conspicuous T-wave inversions in the inferior leads and in V1-V6.

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Embolism Pulmonary Tachycardia 98

American College of Cardiology

OCTOBER 7, 2024

The following are key points to remember from a review comparing international clinical practice guideline recommendations for acute pulmonary embolism (PE):

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Embolism Pulmonary Article 54

Frontiers in Cardiovascular Medicine

JULY 24, 2024

Chronic Thromboembolic Pulmonary Hypertension (CTEPH) is a severe and complex condition that evolves from unresolved pulmonary embolism, leading to fibrotic obstruction of pulmonary arteries, pulmonary hypertension, and potential right heart failure.

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Pulmonary Hypertension Angioplasty Pharmacology 52

NEJM Journal Watch - Cardiology

NOVEMBER 20, 2024

Among patients with low-risk pulmonary embolism, 18 months of anticoagulation significantly reduced its recurrence, compared with 6 months of treatment.

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Embolism Pulmonary Cancer 40

DAIC

DECEMBER 13, 2023

Pulmonary arterial hypertension, a form of high blood pressure that occurs in the lungs, is a target of research by Cedars-Sinai investigators. Pulmonary arterial hypertension is a rare disease, affecting fewer than 100 people per million. Siegel Family Foundation Distinguished Professor and senior author of the study. “We

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Pulmonary Hypertension Blood Pressure Research 105

Circulation

NOVEMBER 11, 2024

Introduction:Obesity is rising in prevalence worldwide and co-exists in patients with group 1 pulmonary hypertension (PH). Despite having group 1 PH, pulmonary capillary wedge pressure (PCWP) was higher with obesity (13.8 ± 6.3 0002) and lower pulmonary vascular resistance (PVR, 7.9 ± 5.2 vs 10.4 ± 6.5 vs 4.5 ± 1.8 mm of Hg, p=.001)

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Obesity Pulmonary Hypertension Diabetes 40

Frontiers in Cardiovascular Medicine

JULY 2, 2024

This study aims to present our institutional experience and the outcomes of pulmonary endarterectomy for PAS.MethodsWe gathered clinical characteristics, intraoperative data, postoperative outcomes, and prognosis information from PAS patients who underwent surgical treatment at our institution between December 2016 and September 2023.ResultsA

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Pulmonary Outcomes 52

Circulation

NOVEMBER 11, 2024

Introduction:Inflammation is a key driver in the development of pulmonary arterial hypertension (PAH). The pulmonary vasculature was evaluated histologically. Rats administered fluconazole had augmented RV function with increased percent RV free wall thickness change (D), RV ejection fraction (E) and RV-pulmonary arterial coupling (F).

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Pulmonary Hypertension Innovation Exercise 40

HeartRhythm

OCTOBER 21, 2024

Pulmonary vein isolation (PVI) by pulsed-field ablation (PFA) has demonstrated encouraging clinical results for the treatment of atrial fibrillation (AF)1,2. This study aims to assess procedural characteristics, safety, and clinical outcomes of PFA-based PVI in patients with a LCPV.

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Pulmonary Ablation Atrial Fibrillation Outcomes 40

Medical Xpress - Cardiology

MAY 2, 2024

This difference becomes clear in pulmonary hypertension, in which only the lungs' blood vessels stiffen progressively, leading to chronic lung disease, heart failure and death. Blood vessels in the lungs aren't like the others in the body.

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Pulmonary Hypertension Heart Failure 71

Journal of Cardiothoracic Surgery

JULY 12, 2024

Extralobar pulmonary sequestration is located outside the lung parenchyma and is covered by a separated pleural sac, which comprises approximately 25% of all pulmonary sequestration.

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Pulmonary 52

Medical Xpress - Cardiology

OCTOBER 30, 2024

Findings from the first international randomized controlled trial to compare patient outcomes following treatment with large-bore mechanical thrombectomy (LBMT) versus catheter-directed thrombolysis (CDT) for intermediate-risk pulmonary embolism (PE) show that LBMT is superior with respect to the hierarchically-tested aggregated outcome of all-cause (..)

Embolism 52

Embolism Pulmonary ICU Outcomes 52

DAIC

SEPTEMBER 4, 2024

The pivotal trial will study the Vertex Pulmonary Embolectomy System, which incorporates Jupiter’s Endoportal Control platform technology into an endovascular procedure intended to treat Acute Pulmonary Embolism (PE) with an unprecedented level of control and precision. pivotal study (NCT06576427).

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Pulmonary Embolism Technology Anatomy 52

Journal of Cardiothoracic Surgery

SEPTEMBER 8, 2024

Some pulmonary tuberculosis patients may require lung resection surgery. Postoperative pulmonary rehabilitation is essential to restore the lung function and maintain quality of life. We aimed to study the pul.

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Pulmonary Quality of Life Nursing Exercise 52

Heart BMJ

AUGUST 26, 2024

Chronic thromboembolic pulmonary hypertension (CTEPH) is a complex pulmonary vascular disorder that involves major vessel and microvascular disease components. Fibrotic obstructions resulting from unresolved pulmonary emboli constitute the major vessel disease component.

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Pulmonary Hypertension Biomarkers Angioplasty 52

Dr. S. Venkatesan MD

OCTOBER 15, 2024

A new Intelligent thrombo-suction catheter system , is being introduced for treatment of acute pulmonary embolism.This device regulates the force with which thrombus is sucked , with less injury and bleeding and better outcomes. They have become a Integral tool kit in peripheral arterial, venous and also pulmonary thrombosis.We

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Technology Pulmonary Embolism Innovation 52

Frontiers in Cardiovascular Medicine

OCTOBER 10, 2024

years, and the time from computed tomography pulmonary angiography (CTPA) diagnosis to interventional treatment averaged 2.8 ± 2.2 years, and the time from computed tomography pulmonary angiography (CTPA) diagnosis to interventional treatment averaged 2.8 ± 2.2 m, with an average age of 62.0 ± 16.0 m, with an average age of 62.0 ± 16.0

Embolism 52

Embolism Pulmonary Chest Pain 52

DAIC

JANUARY 29, 2024

They looked at anonymous results for 57,531 adult patients who underwent pulmonary resection—removal of all or part of a lung—between January 2009 and June 2021. occurrence of postoperative PE in patients undergoing a first-time pulmonary resection for lung cancer. occurrence of postoperative VTE and a 1.3%

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Cancer Pulmonary Research Blood Clot 116

All About Cardiovascular System and Disorders

APRIL 7, 2024

Transcript of the video: Now we will discuss a chest X-ray showing antler sign in pulmonary venous hypertension. So, the shape of the upper lobe vessels in venous hypertension, pulmonary venous hypertension, will be resembling the antlers of the stag. For a change, first we will see the picture of a stag, with antlers.

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Pulmonary Hypertension General Cardiology 52

Med Page Today

DECEMBER 12, 2023

(MedPage Today) -- Stable patients with pulmonary vascular disease (PVD) tolerated travel to high altitudes fairly well with frequent monitoring and supplemental oxygen therapy provided as necessary, a field study found. Despite the perceived.

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Pulmonary Hypertension 105