This site uses cookies to improve your experience. To help us insure we adhere to various privacy regulations, please select your country/region of residence. If you do not select a country, we will assume you are from the United States. Select your Cookie Settings or view our Privacy Policy and Terms of Use.
Cookie Settings
Cookies and similar technologies are used on this website for proper function of the website, for tracking performance analytics and for marketing purposes. We and some of our third-party providers may use cookie data for various purposes. Please review the cookie settings below and choose your preference.
Used for the proper function of the website
Used for monitoring website traffic and interactions
Cookie Settings
Cookies and similar technologies are used on this website for proper function of the website, for tracking performance analytics and for marketing purposes. We and some of our third-party providers may use cookie data for various purposes. Please review the cookie settings below and choose your preference.
Strictly Necessary: Used for the proper function of the website
Performance/Analytics: Used for monitoring website traffic and interactions
IntroductionPercutaneous balloon valvuloplasty is the treatment of choice for critical pulmonary valve stenosis (CPS) and pulmonary valve atresia with intact ventricular septum (PA/IVS) if the ventricle has a suitable size. years), were included. years), were included.
Nature Reviews Cardiology, Published online: 07 August 2024; doi:10.1038/s41569-024-01064-4 In this Review, Ghofrani and colleagues discuss the mechanisms underlying the development of pulmonary arterial hypertension, provide an overview of approved therapies and describe the predominantly non-vasodilatory drugs that are currently being tested in clinical (..)
(MedPage Today) -- The FDA approved sotatercept (Winrevair) for treating pulmonary arterial hypertension (PAH) in adults, Merck announced on Tuesday. A novel activin signaling inhibitor, sotatercept is indicated to increase exercise capacity.
Pulmonary artery sling (PAS) is an uncommon congenital anomaly in which the left pulmonary artery (LPA) originates abnormally from the posterior aspect of the right pulmonary artery (RPA). The LPA then traverses between the trachea and esophagus, resulting in compression of the lower trachea.
This difference becomes clear in pulmonary hypertension, in which only the lungs' blood vessels stiffen progressively, leading to chronic lung disease, heart failure and death.
6, 2025 Medtronic plc hasannounced it received CE ( Conformit Europenne ) Mark for the Harmony Transcatheter Pulmonary Valve (TPV) System, a minimally invasive alternative to open-heart surgery for congenital heart disease patients with native or surgically repaired right ventricular outflow tract (RVOT).
Patients with acute pulmonary embolism (PE) have a wide spectrum of clinical presentations, from incidental findings to sudden cardiac death. Here, we propose an algorithm where the role of the Pulmonary Embolism Response Team (PERT) is reinforced. In this review, the challenges related to the identification of a CiT are highlighted.
Pulmonary sequestration (PS) is a rare congenital lung developmental anomaly characterized by abnormal lung tissue that receives its blood supply from the aorta. Utilizing the Seldinger technique, we accessed the right femoral artery and vein for angiography, confirming the abnormal vessels supplying the pulmonary cyst.
(MedPage Today) -- Despite guidelines recommending other anticoagulants for people hospitalized with acute pulmonary embolism (PE), old habits and misconceptions have kept unfractionated heparin (UFH) the initial choice for many physicians in the.
The increased use of radiofrequency ablation (RFA) for atrial fibrillation (AF) has led to a rise in cases of pulmonary vein stenosis or occlusion (PVS/O) as a complication. The actual frequency of pulmonary vein (PV) occlusion remains a topic of debate.
Bioelectronic medicine scientists at The Feinstein Institutes for Medical Research used noninvasive, splenic focused ultrasound stimulation (sFUS) and found they can reduce inflammation and improve symptoms of pulmonary arterial hypertension (PAH). The research team delivered sFUS to cohorts of preclinical models with the disease.
Chronic Thromboembolic Pulmonary Hypertension (CTEPH) is a severe and complex condition that evolves from unresolved pulmonary embolism, leading to fibrotic obstruction of pulmonary arteries, pulmonary hypertension, and potential right heart failure.
(MedPage Today) -- Mortality rates were high among patients with high-risk pulmonary embolism (PE), with the worst outcomes in those with hemodynamic collapse, according to a retrospective analysis of the Pulmonary Embolism Response Team (PERT.
BackgroundCurrent evidence suggests that cardiovascular disease (CVD) plays a role in the progression of chronic obstructive pulmonary disease (COPD). However, the relationship between CVD and the severity of COPD remains inadequately understood.
Pulmonary arterial hypertension is a disease of the pulmonary vasculature, resulting in elevated pressure in the pulmonary arteries and disrupting the physiological coordination between the right heart and the pulmonary circulation. Journal of the American Heart Association, Ahead of Print.
The use of hormone replacement therapy (HRT) may be associated with improved pulmonary hypertension in women, according to research presented at the ATS 2024 International Conference held May 17–22 in San Diego.
These are typical ECG changes that may indicate a pulmonary embolism. The patient has an acute pulmonary embolism. Sinus tachycardia may be present in acute pulmonary embolism. We see a sinus rhythm with left anterior fascicular block (LAFB) and conspicuous T-wave inversions in the inferior leads and in V1-V6.
milla1cf Tue, 02/27/2024 - 17:29 February 27, 2024 — Aria CV, Inc , a developer of medical devices treating pulmonary hypertension, today announced the first patient was implanted with the Gen 2 Aria CV Pulmonary Hypertension System as part of the ASPIRE PH clinical trial at Ascension St. Ashwin Ravichandran and Scott Hittinger.
“This latest patent further secures the broad therapeutic potential of brilaroxazine for inflammatory conditions driven by underlying disruption in serotonin signaling like pulmonary hypertension,” said Laxminarayan Bhat, Ph.D. Founder, President, and CEO. Brilaroxazine has already received Orphan Drug Designation by the U.S.
Pulmonary arterial hypertension (PAH) is a devastating and progressive disease with limited treatment options. Endothelial haploinsufficiency of RAB7 caused spontaneous pulmonary hypertension (PH) in mice. Here, we explored the role of RAB7 in endothelial cell (EC) function and lung vascular homeostasis.
(MedPage Today) -- In March, we reported on back-to-back FDA approvals for two treatments in pulmonary arterial hypertension (PAH). In this report, we follow up on what has happened since. After the FDA approved both combination macitentan/tadalafil.
Pulmonary arterial hypertension, a form of high blood pressure that occurs in the lungs, is a target of research by Cedars-Sinai investigators. Pulmonary arterial hypertension is a rare disease, affecting fewer than 100 people per million. Siegel Family Foundation Distinguished Professor and senior author of the study. “We
Infusions of potentially therapeutic cells derived from the heart are safe for people with pulmonary arterial hypertension, a form of high blood pressure that occurs in the blood vessels of the lungs and typically affects middle-aged women, according to a new study.
(MedPage Today) -- Stable patients with pulmonary vascular disease (PVD) tolerated travel to high altitudes fairly well with frequent monitoring and supplemental oxygen therapy provided as necessary, a field study found. Despite the perceived.
They looked at anonymous results for 57,531 adult patients who underwent pulmonary resection—removal of all or part of a lung—between January 2009 and June 2021. occurrence of postoperative PE in patients undergoing a first-time pulmonary resection for lung cancer. occurrence of postoperative VTE and a 1.3%
PDA combined with pulmonary artery aneurysm (PAA) due to IE is rare in children. Patent ductus arteriosus (PDA) is one of the most common forms of congenital heart disease (CHD). Infectious endocarditis (IE) is a rare but serious complication of PDA. In this report, we report a rare pediatric PDA case, complicated with PAA due to IE.
Pulmonary vein isolation (PVI) is the cornerstone of interventional treatment for atrial fibrillation (AF). Pulsed-field ablation (PFA), a novel non-thermal modality, was recently introduced and is now available with four different FDA-approved systems from three different manufacturers.
During the surgery, the malfunctioning aortic valve is replaced with the patients own healthy pulmonary valvea technique called an autograftand the pulmonary valve replaced with donor tissue. Three patients underwent the Ross-Konno procedure, in which the left-sided outflow root is enlarged to fit the pulmonary autograft.
(MedPage Today) -- LONG BEACH, Calif. -- Big Data may provide some answers to the many questions surrounding advanced catheter-based pulmonary embolism (PE) therapies, a buzzing field that otherwise has little evidence from real-world practice.
Results of Tenax Therapeutics’ Phase 2 HELP study of levosimendan in patients with pulmonary hypertension (PH) with heart failure with preserved ejection fraction (HFpEF) demonstrated that I.V. Getty Images milla1cf Mon, 05/06/2024 - 10:48 May 6, 2024 — Tenax Therapeutics, Inc. ,
Mechanical thrombectomy (MT) is safe and effective in real-world, high-risk patients with pulmonary embolism (PE), according to a study published online Oct. 31 in the Journal of the Society for Cardiovascular Angiography & Interventions.
This difference becomes clear in pulmonary hypertension, in which only the lungs' blood vessels stiffen progressively, leading to chronic lung disease, heart failure and death. Blood vessels in the lungs aren't like the others in the body.
In our study, we aim to explore the structural differences between the aortic root and the pulmonary artery to better understand the process of pulmonary autograft dilatation during the Ross procedure.
Panelists discuss how the coexistence of heart disease and chronic obstructive pulmonary disease (COPD) requires careful management as these conditions significantly impact each other. Key treatable traits in COPD-associated pulmonary hypertension include hypoxemia, inflammation, and right ventricular dysfunction.
Up to 50% of patients with pulmonary embolism (PE) experience hemodynamic instability and approximately 70% of patients who die of PE experience an accelerated cascade of symptoms within the first hours of onset of symptoms, thus necessitating rapid evaluation and intervention. Journal of the American Heart Association, Ahead of Print.
(MedPage Today) -- LOS ANGELES -- For surgeons already split on their preference of inhaled pulmonary vasodilator to prevent postoperative right ventricular (RV) failure, a shifting market is not helping decision-making, as highlighted by a debate.
New-onset arrhythmias are common in patients with chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA). However, scarce data exists regarding arrhythmia risk in overlap syndrome (OS), encompassing COPD and OSA.
Patients were categorised into cardiac or pulmonary origin groups based on initial admission. True cardiac origin was confirmed in 96 patients in a sensitivity analysis of 129 patients with a high probability of cardiac origin initially misdiagnosed as pulmonary origin predicted by AI-ECG.
Infusions of potentially therapeutic cells derived from the heart are safe for people with pulmonary arterial hypertension, a form of high blood pressure that occurs in the blood vessels of the lungs and typically affects middle-aged women, according to a study led by Cedars-Sinai investigators.
However, the cause and risk factors for mortality remain uncertain.MethodsThis retrospective, singlecenter study identified children with primary and secondary pulmonary vein stenosis through a cardiac catheterization database. 95% CI, 2.214.1];P<0.001). P<0.001). 95% CI, 1.610.4];P=0.004), 95% CI, 1.111.5];P=0.032),
We organize all of the trending information in your field so you don't have to. Join thousands of users and stay up to date on the latest articles your peers are reading.
You know about us, now we want to get to know you!
Let's personalize your content
Let's get even more personalized
We recognize your account from another site in our network, please click 'Send Email' below to continue with verifying your account and setting a password.
52 
Let's personalize your content