Journal of Clinical Investigation - Cardiology

FEBRUARY 1, 2024

Pulmonary arterial hypertension (PAH) is a devastating and progressive disease with limited treatment options. Endothelial haploinsufficiency of RAB7 caused spontaneous pulmonary hypertension (PH) in mice. Here, we explored the role of RAB7 in endothelial cell (EC) function and lung vascular homeostasis.

Pulmonary 98

Pulmonary Hypertension 98

Med Page Today

OCTOBER 7, 2024

(MedPage Today) -- BOSTON -- Sodium-glucose cotransporter-2 (SGLT2) inhibitors were linked to long-term reductions in mortality risk among patients with pulmonary arterial hypertension (PAH), according to an observational cohort study.

Pulmonary 111

Pulmonary Hypertension Outcomes 111

Science Daily - Heart Disease

AUGUST 21, 2024

A new study has found that asporin, a protein encoded by the ASPN gene, plays a protective role in pulmonary arterial hypertension (PAH).

Pulmonary 101

Pulmonary Hypertension 101

ECG Guru

JULY 14, 2023

These are typical ECG changes that may indicate a pulmonary embolism. The patient has an acute pulmonary embolism. Sinus tachycardia may be present in acute pulmonary embolism. We see a sinus rhythm with left anterior fascicular block (LAFB) and conspicuous T-wave inversions in the inferior leads and in V1-V6.

Embolism 98

Embolism Pulmonary Tachycardia 98

DAIC

JULY 10, 2024

“This latest patent further secures the broad therapeutic potential of brilaroxazine for inflammatory conditions driven by underlying disruption in serotonin signaling like pulmonary hypertension,” said Laxminarayan Bhat, Ph.D. Founder, President, and CEO. Brilaroxazine has already received Orphan Drug Designation by the U.S.

Pulmonary 111

Pulmonary Hypertension Pharmacology Biomarkers 111

Medical Xpress - Cardiology

MAY 19, 2024

The use of hormone replacement therapy (HRT) may be associated with improved pulmonary hypertension in women, according to research presented at the ATS 2024 International Conference held May 17–22 in San Diego.

Pulmonary 95

Pulmonary Hypertension Research 95

DAIC

JANUARY 29, 2024

They looked at anonymous results for 57,531 adult patients who underwent pulmonary resection—removal of all or part of a lung—between January 2009 and June 2021. occurrence of postoperative PE in patients undergoing a first-time pulmonary resection for lung cancer. occurrence of postoperative VTE and a 1.3%

Cancer 116

Cancer Pulmonary Research Blood Clot 116

DAIC

DECEMBER 13, 2023

Pulmonary arterial hypertension, a form of high blood pressure that occurs in the lungs, is a target of research by Cedars-Sinai investigators. Pulmonary arterial hypertension is a rare disease, affecting fewer than 100 people per million. Siegel Family Foundation Distinguished Professor and senior author of the study. “We

Pulmonary 105

Pulmonary Hypertension Blood Pressure Research 105

Medical Xpress - Cardiology

JANUARY 19, 2024

A research team has discovered a possible therapeutic target for pulmonary hypertension.

Pulmonary 98

Pulmonary Hypertension Cardiac Function Research 98

Med Page Today

DECEMBER 12, 2023

(MedPage Today) -- Stable patients with pulmonary vascular disease (PVD) tolerated travel to high altitudes fairly well with frequent monitoring and supplemental oxygen therapy provided as necessary, a field study found. Despite the perceived.

Pulmonary 105

Pulmonary Hypertension 105

Med Page Today

MAY 4, 2024

(MedPage Today) -- LONG BEACH, Calif. -- Big Data may provide some answers to the many questions surrounding advanced catheter-based pulmonary embolism (PE) therapies, a buzzing field that otherwise has little evidence from real-world practice.

Embolism 95

Embolism Pulmonary 95

Medical Xpress - Cardiology

JULY 8, 2024

Pulmonary hypertension is a very serious disease that leads to heart failure and death in many patients.

Pulmonary 86

Pulmonary Hypertension Physiology Heart Failure 86

DAIC

MAY 6, 2024

Results of Tenax Therapeutics’ Phase 2 HELP study of levosimendan in patients with pulmonary hypertension (PH) with heart failure with preserved ejection fraction (HFpEF) demonstrated that I.V. Getty Images milla1cf Mon, 05/06/2024 - 10:48 May 6, 2024 — Tenax Therapeutics, Inc. ,

Preserved Ejection Fraction 105

Preserved Ejection Fraction Heart Failure Pulmonary Hypertension 105

Science Daily - Heart Disease

DECEMBER 13, 2023

Infusions of potentially therapeutic cells derived from the heart are safe for people with pulmonary arterial hypertension, a form of high blood pressure that occurs in the blood vessels of the lungs and typically affects middle-aged women, according to a new study.

Pulmonary 94

Pulmonary Hypertension Blood Pressure 94

Medical Xpress - Cardiology

DECEMBER 10, 2023

Mechanical thrombectomy (MT) is safe and effective in real-world, high-risk patients with pulmonary embolism (PE), according to a study published online Oct. 31 in the Journal of the Society for Cardiovascular Angiography & Interventions.

Embolism 87

Embolism Pulmonary 87

Journal of Cardiothoracic Surgery

OCTOBER 31, 2024

In our study, we aim to explore the structural differences between the aortic root and the pulmonary artery to better understand the process of pulmonary autograft dilatation during the Ross procedure.

Pulmonary 80

Pulmonary Aortic Research 80

Medical Xpress - Cardiology

MAY 2, 2024

This difference becomes clear in pulmonary hypertension, in which only the lungs' blood vessels stiffen progressively, leading to chronic lung disease, heart failure and death. Blood vessels in the lungs aren't like the others in the body.

Pulmonary 75

Pulmonary Hypertension Heart Failure 75

Journal of Cardiothoracic Surgery

JANUARY 2, 2024

While the role of low-dose computed tomography (CT) in lung cancer screening is established, its limitations in detailing pulmonary vascular variations are less emphasized. Three-dimensional reconstruction tec.

Pulmonary 78

Pulmonary Cancer 78

Open Heart

OCTOBER 1, 2024

Patients were categorised into cardiac or pulmonary origin groups based on initial admission. True cardiac origin was confirmed in 96 patients in a sensitivity analysis of 129 patients with a high probability of cardiac origin initially misdiagnosed as pulmonary origin predicted by AI-ECG.

Pulmonary 98

Pulmonary Heart Failure 98

Medical Xpress - Cardiology

DECEMBER 13, 2023

Infusions of potentially therapeutic cells derived from the heart are safe for people with pulmonary arterial hypertension, a form of high blood pressure that occurs in the blood vessels of the lungs and typically affects middle-aged women, according to a study led by Cedars-Sinai investigators.

Pulmonary 84

Pulmonary Hypertension Blood Pressure 84

HCPLive

FEBRUARY 6, 2024

These data indicate that in the US, the outpatient management of patients with pulmonary embolism identified as lower-risk may continue to be underutilized.

Embolism 72

Embolism Pulmonary Outpatient 72

Medical Xpress - Cardiology

MARCH 29, 2024

Food and Drug Administration has approved Winrevair (sotatercept-csrk) as an injectable treatment for pulmonary arterial hypertension (PAH) in adults.

Pulmonary 68

Pulmonary Hypertension 68

HeartRhythm

NOVEMBER 7, 2024

Superior vena cava (SVC) conduction delay or isolation during right superior pulmonary vein (RSPV) ablation using thermal ablation technologies has been previously described.1,2 1,2 No reports regarding the impact of pulsed-field ablation (PFA) on the SVC exist.

Ablation 75

Ablation Pulmonary Technology 75

JAMA Cardiology

JULY 23, 2024

This randomized clinical trial investigates the effect of dapagliflozin on right ventricular performance and vascular load during exertion in heart failure with preserved ejection fraction (HFpEF).

Preserved Ejection Fraction 110

Preserved Ejection Fraction Pulmonary Heart Failure 110

HeartRhythm

JANUARY 27, 2024

However, vagal responses and reversible effects on ganglionated plexi (GP) are observed during pulmonary vein isolation (PVI). Pulsed field ablation (PFA) is selective for the myocardium. Anterior-right GP ablation has been proven to effectively prevent vagal responses during radiofrequency-based PVI.

Pulmonary 74

Pulmonary Ablation 74

Heart BMJ

AUGUST 26, 2024

Background Decreased diffusing capacity of the lungs for carbon monoxide (DLco) is associated with microvascular damage in chronic thromboembolic pulmonary hypertension (CTEPH). The LD group had a shorter 6-minute walking distance (324±91 vs 427±114 m) than the ND group but the mean pulmonary artery pressure (mPAP) was similar (38.9±7.3

Angioplasty 52

Angioplasty Pulmonary Exercise Hypertension 52

American College of Cardiology

OCTOBER 7, 2024

The following are key points to remember from a review comparing international clinical practice guideline recommendations for acute pulmonary embolism (PE):

Embolism 56

Embolism Pulmonary Article 56

Society of Thoracic Surgeons - Research

APRIL 2, 2024

News STS Panel Discussion: Predictors of Venous Thromboembolism after Pulmonary Resection for Lung Cancer KCummings Tue, 04/02/2024 - 08:33 1 min read

Cancer 64

Cancer Pulmonary 64

Heart BMJ

AUGUST 26, 2024

LEARNING OBJECTIVES Review the diagnostic pathway for pulmonary arterial hypertension (PAH) in congenital heart disease (CHD). Understand and interpret right heart catheterisation data in pulmonary hypertension related to CHD. Recognise the typical presentation of PAH in patients with CHD. Explore the treatment options for PAH-CHD.

Congenital Heart Disease 52

Congenital Heart Disease Pulmonary Congenital Hypertension 52

Journal of Cardiothoracic Surgery

AUGUST 20, 2024

This research evaluates the effect of balloon pulmonary angioplasty (BPA) on cardiac electrophysiological changes in patients with chronic thromboembolic pulmonary hypertension (CTEPH).

Angioplasty 52

Angioplasty Pulmonary Hypertension Electrophysiology 52

Dr. Smith's ECG Blog

JUNE 17, 2024

He was started on a heparin drip and CTA of the chest was ordered to rule out pulmonary embolism. This is a case like many others posted (see list below) and the EKG from the patient’s original presentation can be quickly recognized as diagnostic for pulmonary embolism. In fact, Kosuge et al. Accessed May 28, 2024. This is a quiz.

Chest Pain 141

Chest Pain Embolism Pulmonary Tachycardia 141

HCPLive

JANUARY 31, 2024

A recent analysis found risk factors linked to an embolism after VTE included Black race, interstitial fibrosis, advanced-stage disease, and increased operative duration.

Risk Factors 105

Risk Factors Pulmonary Embolism 105

American College of Cardiology

AUGUST 7, 2024

In this week’s View, Dr. Eagle looks at post-capillary pulmonary hypertension in heart failure and the revised European guideline definition. He then explores obesity in adolescents and its impact on our societal health.

Obesity 61

Obesity Pulmonary Hypertension TAVR 61

HCPLive

MAY 22, 2024

Sisson discusses the adoption of 2021 ATS / ERS guidelines, as well as the need for complementary testing and imagine to contextualize the full pulmonary patient.

Pulmonary 59

Pulmonary 59

NEJM Journal Watch - Cardiology

NOVEMBER 20, 2024

Among patients with low-risk pulmonary embolism, 18 months of anticoagulation significantly reduced its recurrence, compared with 6 months of treatment.

Embolism 61

Embolism Pulmonary Cancer 61

Society of Thoracic Surgeons - Surgeon

OCTOBER 16, 2024

Resource Pulmonary Resection for Lung Cancer Risk Calculator gmckinney Wed, 10/16/2024 - 07:59 The new pulmonary resection for lung cancer risk calculator is engineered using contemporary data from the STS General Thoracic Surgery Database.

Cancer 52

Cancer Pulmonary Hospital Outcomes 52

Circulation: Cardiovascular Interventions

JANUARY 24, 2024

BACKGROUND:Prior clinical trials have demonstrated the efficacy of ultrasound-facilitated catheter-directed thrombolysis (USCDT) for the treatment of acute intermediate-risk pulmonary embolism (PE) using reduced thrombolytic doses and shorter infusion durations.

Embolism 75

Embolism Thrombolysis Ultrasound Pulmonary 75