European Journal of Heart Failure

MARCH 19, 2025

Semaglutide reduces late sodium current (I Na ) and diastolic calcium (Ca) sparks in human cardiomyocytes from aortic stenosis (AS) and end-stage heart failure with reduced ejection fraction (HFrEF) patients, thereby increasing Ca transients. However, the exact mechanisms underlying its cardioprotective actions remain unclear.

Preserved Ejection Fraction 40

Preserved Ejection Fraction Heart Failure Stenosis Aortic 40

Open Heart

MARCH 8, 2024

Methods This proof-of-concept study used four-dimensional (4D) flow cardiovascular MR (4D flow CMR) data of five healthy controls, five patients with heart failure with preserved ejection fraction and five patients with aortic stenosis (AS). Visual assessment of flow vectors was used to assess helicity and vorticity.

Preserved Ejection Fraction 52

Preserved Ejection Fraction Aortic Biomarkers Heart Failure 52

Dr. S. Venkatesan MD

APRIL 18, 2024

We know a small ASD decompresses mitral stenosis, and the combination of ASD and MS, Lutembacher, is a well-known syndrome called Lutembacher. Shah, author of Atrial Shunt Device Effects on Cardiac Structure and Function in Heart Failure With Preserved Ejection Fraction: The REDUCE LAP-HF II Randomized Clinical Trial.

Preserved Ejection Fraction 40

Preserved Ejection Fraction Pulmonary Congenital Heart Disease VSD 40

DAIC

FEBRUARY 29, 2024

24: Joint American College of Cardiology/Journal of the American College of Cardiology Late-Breaking Clinical Trials (Session 402) Saturday, April 6 9:30 – 10:30 a.m.

Aortic valve 103

Aortic valve Myocardial Infarction Aortic Blood Pressure 103

European Journal of Heart Failure

DECEMBER 13, 2023

Venn diagram highlighting the main similarities and differences between heart failure with preserved ejection fraction (HFpEF) and aortic stenosis with preserved ejection fraction (ASpEF). HFpEF and ASpEF patients showed similar demographic distribution and biohumoral profiles.

Preserved Ejection Fraction 40

Preserved Ejection Fraction Heart Failure Stenosis Aortic valve 40

Open Heart

JANUARY 8, 2024

Background A quarter of patients with severe aortic stenosis (AS) were asymptomatic, and only a third of them survived at the end of 4 years. We intended to study the effect of early AVR (eAVR) in this subset of asymptomatic patients with preserved left ventricle function. We noticed no difference in MI, stroke and major bleeding.

Aortic valve 98

Aortic valve Aortic Preserved Ejection Fraction Stenosis 98

Heart BMJ

NOVEMBER 27, 2023

Objective To characterise the mechanics responsible for the reduced ejection fraction (rEF) in high-gradient severe aortic stenosis (AS). They included 9 patients with rEF (EF <50%) and 12 with preserved ejection fraction (pEF) (EF >50%). cm 2 and mean gradient (MG) >40 mm Hg) were included.

Stenosis 40

Stenosis Aortic Preserved Ejection Fraction Aortic valve 40