JAMA Cardiology

NOVEMBER 15, 2024

In this case series study, pulmonary artery systolic, diastolic, and mean pressures of 2 participants with obesity and heart failure with preserved ejection fraction were measured at zero gravity during parabolic flight to assess the effect of external constraint on left ventricular filling pressures.

Preserved Ejection Fraction 73

Preserved Ejection Fraction Heart Failure Obesity Pulmonary 73

Journal of the American Heart Association

DECEMBER 29, 2023

BackgroundPulmonary hypertension (PH) is highly prevalent in patients with heart failure with preserved ejection fraction (HFpEF), and it is a strong predictor of adverse outcomes. Journal of the American Heart Association, Ahead of Print. TAPSE/PASP and TAS’/PASP can be useful parameters to detect PH in patients with HFpEF.

Preserved Ejection Fraction 40

Preserved Ejection Fraction Pulmonary Heart Failure Hypertension 40

Frontiers in Cardiovascular Medicine

FEBRUARY 8, 2024

This study investigates the utility of echocardiographic left ventricular (LV) to left atrial (LA) volume ratio in estimating the resting FP in patients with dyspnoea and preserved ejection fraction (EF). Echocardiographic data were obtained 1.5 ± 1.0 h h after cardiac catheterisation.

Preserved Ejection Fraction 59

Preserved Ejection Fraction Atrial Fibrillation Pulmonary 59

European Journal of Heart Failure

OCTOBER 30, 2023

Haemodynamic curve morphology is displayed for right atrial (RAP), right ventricular (RVP), mean pulmonary artery (PAP), and pulmonary capillary wedge pressure (PAWP). 2–4 points denotes an intermediate risk for heart failure with preserved ejection fraction (HFpEF) at non-invasive testing at rest.

Preserved Ejection Fraction 40

Preserved Ejection Fraction Heart Failure Exercise Pulmonary 40

HeartRhythm

APRIL 30, 2024

Left atrial and pulmonary artery pressure (PAP) elevation can reflect severity and dynamic status of heart failure (HF) in HF with preserved ejection fraction (pEF). Atrial fibrillation (AF) worsens HFpEF progression and pump failure, but catheter ablation can restore rhythm control in this population.

Preserved Ejection Fraction 40

Preserved Ejection Fraction Atrial Fibrillation Heart Failure Ablation 40

European Journal of Heart Failure

DECEMBER 7, 2023

Increasing severity of obesity is associated with multiple characteristics that may contribute to the development or worsening of heart failure (HF) with preserved ejection fraction (HFpEF). Pulmonary vascular resistance at rest and exercise decreased with higher BMI.

Preserved Ejection Fraction 40

Preserved Ejection Fraction Obesity Heart Failure BMI 40

American College of Cardiology

JULY 11, 2024

What is the safety and efficacy of tadalafil in patients with heart failure with preserved ejection fraction (HFpEF) and combined postcapillary and precapillary pulmonary hypertension (CpcPH)?

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Preserved Ejection Fraction Heart Failure Pulmonary Hypertension 53

DAIC

APRIL 22, 2024

RELIEVE-HF failed to meet its primary efficacy endpoint and did not reduce heart failure events or improve quality of life in heart failure patients with a preserved ejection fraction (HFpEF).

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Preserved Ejection Fraction Quality of Life Heart Failure Pacemaker 105

Journal of the American Heart Association

DECEMBER 29, 2023

Journal of the American Heart Association, Ahead of Print.

Preserved Ejection Fraction 40

Preserved Ejection Fraction Pulmonary Heart Failure Hypertension 40

Circulation

MARCH 9, 2025

Circulation, Volume 151, Issue 10 , Page e686-e686, March 11, 2025.

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Preserved Ejection Fraction Article Heart Failure Pulmonary 45

Circulation

MARCH 16, 2025

Circulation, Volume 151, Issue 11 , Page e763-e763, March 18, 2025.

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Preserved Ejection Fraction Heart Failure Pulmonary Hypertension 45

JAMA Cardiology

JULY 23, 2024

Among patients with heart failure with preserved ejection fraction (HFpEF), right ventricular (RV) dysfunction is strongly associated with an increased risk of morbidity and mortality.

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Preserved Ejection Fraction Heart Failure Pulmonary Exercise 44

Circulation: Heart Failure

DECEMBER 18, 2023

P=0.02) and with pulmonary wedge pressure but following different slopes at rest and during exercise (R2=0.49;P<0.001). mm Hg in HF with preserved ejection fraction patients and was also exacerbated by exercise. RESULTS:In hypertrophic cardiomyopathy, RT (estimated marginal mean [95% CI]) was 3.4 (0.4–6.4)

Preserved Ejection Fraction 40

Preserved Ejection Fraction Exercise Cardiomyopathy Heart Failure 40

Dr. S. Venkatesan MD

APRIL 18, 2024

This is to create a small regulatory orifice in the IAS ( A complicated term for a small ASD ) to decompress the LA and reduce pulmonary congestive symptoms. Shah, author of Atrial Shunt Device Effects on Cardiac Structure and Function in Heart Failure With Preserved Ejection Fraction: The REDUCE LAP-HF II Randomized Clinical Trial.

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Preserved Ejection Fraction Pulmonary Congenital Heart Disease VSD 40

Dr. S. Venkatesan MD

AUGUST 3, 2024

However, It is surprising even in chronic pulmonary hypertension , the degree of RVH is not constant and homogenous.This is because , different parts of RV chamber has different wall thickness.Further, the pressure distribution from PA to RV is uneven. This may be correct when there is acute raise in RV after load, as in PE.

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Preserved Ejection Fraction Heart Failure Pulmonary Heart Dysfunction 52

Circulation

NOVEMBER 11, 2024

The CardioMEMS PA (pulmonary artery) sensor allows remote pulmonary artery diastolic (PAD) pressure monitoring to adjust diuresis in heart failure with preserved ejection fraction (HFpEF).

Preserved Ejection Fraction 40

Preserved Ejection Fraction Cardiomyopathy Heart Failure Pulmonary 40

Circulation

DECEMBER 21, 2023

BACKGROUND:Metabolic distress is often associated with heart failure with preserved ejection fraction (HFpEF) and represents a therapeutic challenge. Circulation, Ahead of Print. Metabolism-induced systemic inflammation links comorbidities with HFpEF.

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Preserved Ejection Fraction Diet Exercise Heart Failure 45

Circulation

NOVEMBER 11, 2024

Intro:Drug Development for Heart failure with Preserved Ejection Fraction (HFpEF) is a major challenge facing cardiovascular research due to its complex pathophysiology and existence of comorbidities, leading to recognize distinct HFpEF phenogroups. vs. Ctrl), indicative of pulmonary congestion.

Preserved Ejection Fraction 40

Preserved Ejection Fraction Hypertension Blood Pressure Obesity 40

European Journal of Heart Failure

APRIL 13, 2025

The beneficial effects of finerenone in patients with heart failure (HF) and mildly reduced or preserved ejection fraction were consistent, regardless of a history of chronic obstructive pulmonary disease (COPD) status.

Preserved Ejection Fraction 40

Preserved Ejection Fraction Heart Failure Pulmonary Peripheral Arterial Disease 40

DAIC

MARCH 25, 2025

25 include Efficacy and safety of finerenone across the spectrum of kidney risk in heart failure with mildly reduced or preserved ejection fraction during the session;"Innovations and Insights in Heart Failure With Preserved Ejection Fraction: Emerging Therapies, Biomarkers and Mechanistic Studies."

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Preserved Ejection Fraction Heart Failure Kidney Disease Research 52

European Journal of Heart Failure

DECEMBER 13, 2023

BMI, body mass index; CI, confidence interval; LVEF, left ventricular ejection fraction; NT-proBNP, N-terminal pro-B-type natriuretic peptide. ABSTRACT Aim Chronic obstructive pulmonary disease (COPD) is common in heart failure with a mildly reduced or preserved ejection fraction (HFmrEF/HFpEF) and is associated with worse outcomes.

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Preserved Ejection Fraction Heart Failure Pulmonary Quality of Life 75

European Journal of Heart Failure

DECEMBER 13, 2023

Venn diagram highlighting the main similarities and differences between heart failure with preserved ejection fraction (HFpEF) and aortic stenosis with preserved ejection fraction (ASpEF).

Preserved Ejection Fraction 40

Preserved Ejection Fraction Stenosis Heart Failure Aortic valve 40

European Journal of Heart Failure

DECEMBER 7, 2023

ABSTRACT Background Left atrial (LA) myopathy is increasingly recognized as an important phenotypic trait in heart failure (HF) with preserved ejection fraction (HFpEF). There were 94 patients with events over a median follow-up of 2.9 (IQR 2.92, p = 0.01).

Preserved Ejection Fraction 40

Preserved Ejection Fraction Heart Failure Exercise Atrial Fibrillation 40

DAIC

MARCH 25, 2025

25 include Efficacy and safety of finerenone across the spectrum of kidney risk in heart failure with mildly reduced or preserved ejection fraction during the session;"Innovations and Insights in Heart Failure With Preserved Ejection Fraction: Emerging Therapies, Biomarkers and Mechanistic Studies."

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Preserved Ejection Fraction Heart Failure Research Academic 52

European Journal of Heart Failure

DECEMBER 15, 2024

A summary of effect of sacubitril/valsartan in heart failure with preserved ejection fraction across the age spectrum. All participants in PARAGON-HF were divided into three age groups: <65years, 6574years, and75years.

Preserved Ejection Fraction 40

Preserved Ejection Fraction Heart Failure Laboratory Echocardiogram 40

European Journal of Heart Failure

DECEMBER 29, 2023

HFpEF patients were then categorized a priori into previously-proposed, non-exclusive descriptive clinical trait phenogroups, including cardiometabolic, pulmonary vascular disease, left atrial myopathy, and vascular stiffening phenogroups based on clinical and hemodynamic profiles to contrast pathophysiology and clinical risk.

Preserved Ejection Fraction 40

Preserved Ejection Fraction Exercise Heart Failure Pulmonary 40

Circulation

NOVEMBER 11, 2024

The eventful subjects had a higher prevalence of diabetes, higher estimated pulmonary pressure, lower hemoglobin levels and was less on treatment with renin-angiotensin system inhibitors. Subjects with adverse events during the 6-month treatment were excluded from this analysis.Results:Among a total of 514 participants (82.6 ± 13.9

Preserved Ejection Fraction 40

Preserved Ejection Fraction Heart Failure Diabetes Pulmonary 40

Circulation

NOVEMBER 11, 2024

Introduction:The demographics of patients with pulmonary arterial hypertension (PAH) is shifting towards older age, increased comorbidity burden, and an increase in the risk of left ventricular (LV) diastolic dysfunction. 2022 were included.

Pulmonary 40

Pulmonary Hypertension Preserved Ejection Fraction Outcomes 40

DAIC

MARCH 29, 2024

This causes pulmonary congestion and makes it hard to breathe during activities or even at rest. HFpEF is HF with preserved ejection fraction in which pressure builds up in the heart and lungs due to a stiffened left ventricle. There are two types of HF.

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Preserved Ejection Fraction Heart Failure Quality of Life Hospital 111

Open Heart

FEBRUARY 15, 2023

AFMR is likely to become more common with population ageing, alongside increases in atrial fibrillation and heart failure with preserved ejection fraction; conditions causing atrial dilatation. Advancing age and pulmonary hypertension independently associated with survival in FMR. for all-cause and 1.73, 95% CI 1.60

Bicuspid/Mitral 52

Bicuspid/Mitral Preserved Ejection Fraction Pulmonary Atrial Fibrillation 52

International Journal of Cardiovascular Sciences

OCTOBER 21, 2024

Santos Most Cited Article – Reduction in Hospitalization and Increase in Mortality Due to Cardiovascular Diseases during the COVID-19 Pandemic in Brazil Authors: Paulo Garcia Normando, José de Arimatéia Araujo-Filho, Gabriela de Alcântara Fonseca, Rodrigo Elton Ferreira Rodrigues, Victor Agripino Oliveira, Ludhmila Abrahão Hajjar, André Luiz (..)

Article 52

Article Preserved Ejection Fraction COVID-19 Heart Failure 52

Dr. Smith's ECG Blog

OCTOBER 28, 2023

LVH is a common etiology of heart failure with preserved ejection fraction, as it may results in a stiff ventricle with poor diastolic relaxation. Further ultrasound showed no B-lines (no pulmonary edema). LVH can have very thick-walled ventricles and a correspondingly small LV cavity.

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Preserved Ejection Fraction Sudden Cardiac Death Chest Pain Heart Failure 57

Heart BMJ

NOVEMBER 27, 2023

They included 9 patients with rEF (EF <50%) and 12 with preserved ejection fraction (pEF) (EF >50%). p=0.02), with higher pulmonary pressures (50 vs 30 mm Hg; p=0.04) and more fibrosis (24% vs 13% of left ventricular mass; p=0.03). Methods 21 patients with high-gradient severe AS (aortic valve area (AVA) <1.0

Stenosis 40

Stenosis Aortic Preserved Ejection Fraction Aortic valve 40

Journal of the American Heart Association

MARCH 13, 2025

Outcomes (allcause, cardiovascular, and noncardiovascular death; allcause and HF hospitalizations) were assessed by univariable and multivariable Cox regressions with EF modeled as a spline.

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Preserved Ejection Fraction Heart Failure Peripheral Arterial Disease Cardiomyopathy 70

Open Heart

DECEMBER 3, 2024

Aims Pulmonary hypertension (PHT) appears to be very common in heart failure with preserved ejection fraction but details on its prevalence, severity and prognostic implications have not been well defined.

Pulmonary 52

Pulmonary Preserved Ejection Fraction Hypertension Atrial Fibrillation 52