Frontiers in Cardiovascular Medicine

FEBRUARY 4, 2024

Background Carotid artery atherosclerosis is a major cause of ischemic stroke, and ischemic stroke is the leading cause of morbidity and mortality worldwide. Unfortunately, the reason for the build-up of atherosclerosis plaque is unknown. Moreover, there was an increased miRNA-29c level in patients with cerebral stroke.

Plaque 64

Plaque Diabetes Atherosclerosis Stroke 64

Science Daily - Heart Disease

NOVEMBER 13, 2024

Researchers have identified a new target to treat atherosclerosis, a condition where plaque clogs arteries and causes major cardiac issues, including stroke and heart attack.

Cardiovascular Disease 108

Cardiovascular Disease Heart Attack Heart attacks Plaque 108

Science Daily - Heart Disease

DECEMBER 11, 2024

Investigators who previously found that a daily statin pill helps prevent heart attacks and strokes in people with HIV have now discovered a potential mechanism that may help to stabilize plaques and prevent their rupture in blood vessels.

Heart Attack 110

Heart Attack Heart attacks Plaque Stroke 110

Journal of the American Heart Association

JANUARY 9, 2024

BackgroundProtruding aortic plaque is known to be associated with an increased risk for future cardiac and cerebrovascular events. Coronary plaque characteristics were compared to evaluate coronary plaque vulnerability in patients with protruding aortic plaque on computed tomography angiography.

Plaque 45

Plaque Aortic Myocardial Infarction Kidney Disease 45

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP296-ATP296, February 1, 2025. Introduction:Nonstenotic carotid plaque is found in some patients with otherwise cryptogenic stroke (CS) but also in normal individuals and patients with stroke of known cause (KS). 2.05) (Figure). and incidental in 47.3%. and incidental in 47.3%.

Plaque 40

Plaque Stroke Strokes Ultrasound 40

Frontiers in Cardiovascular Medicine

APRIL 24, 2024

The early detection of plaques by circulating biomarkers is highly clinically relevant to prevent the occurrence of major complications such as stroke or heart attacks. miRNA expression profiles of serum-derived EVs were obtained by small RNA sequencing and in plaque material simultaneously acquired from patients.

Plaque 52

Plaque Biomarkers Circulation Stenosis 52

Science Daily - Heart Disease

MARCH 6, 2024

In some cases, these levels -- specifically high low-density lipoprotein (LDL) cholesterol, often thought of as 'bad cholesterol,' -- were linked to plaque buildup and cardiovascular events, such as heart attack and stroke.

Cholesterol 119

Cholesterol Heart Attack Heart attacks Plaque 119

Medical Xpress - Cardiology

NOVEMBER 13, 2024

Researchers at Case Western Reserve University have identified a new target to treat atherosclerosis, a condition where plaque clogs arteries and causes major cardiac issues, including stroke and heart attack.

Atherosclerosis 89

Atherosclerosis Heart Attack Heart attacks Plaque 89

CTVS

OCTOBER 22, 2024

Did you know that one in four adults will suffer a stroke at some point in their life? A stroke occurs when the carotid arteries, the two main arteries that supply blood to the brain, become narrowed and restrict its flow. This often results from plaque build-up within the arteries known as carotid disease.

Stroke 52

Stroke Strokes Plaque 52

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP116-AWP116, February 1, 2024. Ipsilateral and contralateral carotid artery plaque features were compared, then the carotid artery plaque characteristics on the infarct side were correlated with the infarct pattern.Results:the mean age of subjects included was 68 years old, 79.6%

Plaque 40

Plaque Atherosclerosis Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A42-A42, February 1, 2024. Introduction:A new Plaque-RADS classification (I-IV) is proposed to categorize the degree of carotid plaque instability and risk of embolic ischemic stroke. Prevalence of Plaque-RADS subtypes was analyzed ipsilateral versus contralateral to stroke side.

Plaque 40

Plaque Embolism Stroke Strokes 40

Science Daily - Heart Disease

MARCH 11, 2024

Doctors may be able to leverage the new insights to identify patients at greatest risk of having atherosclerotic plaques break free and cause heart attacks or strokes.

Heart Attack 64

Heart Attack Heart attacks Stroke Strokes 64

CTVS

OCTOBER 30, 2024

Common examples of vascular disease are aneurysms (a dangerous bulge in an artery wall), atherosclerosis (plaque buildup in the… Source Vascular disease affects the body’s vast network of blood vessels, veins and arteries.

Aneurysm 52

Aneurysm Plaque Atherosclerosis Heart Disease 52

Journal of the American Heart Association

NOVEMBER 28, 2023

BackgroundComplex aortic plaque (CAP) is a potential embolic source in patients with cryptogenic stroke (CS). Most studies (74%) used ≥4 mm plaque thickness as the imaging criterion for CAP although ≥1 mm (N=1, CTA), ≥5 mm (N=5, TEE), and ≥6 mm (N=2, CTA) were also reported. 0.41],I2=94%). I2=95%) for TEE; 0.23 (95% CI, 0.15–0.34;I2=87%)

Plaque 40

Plaque Biomarkers Aortic Stroke 40

Medical Xpress - Cardiology

NOVEMBER 13, 2024

However, for people with risks for heart disease, these warning signals can have a negative consequence: they can increase the size of plaque in arteries, making them narrow, and trigger inflammatory events that can cause plaque to rupture. This can set the stage for a heart attack or stroke.

Cardiovascular Disease 75

Cardiovascular Disease Heart Attack Heart attacks Plaque 75

Medical Xpress - Cardiology

OCTOBER 16, 2024

New research published in the Journal of Stroke and Cerebrovascular Diseases confirms that strokes thought to happen in older adults are possible in the younger (defined as 18–50 years old) population.

Blood Clot 52

Blood Clot Cerebrovascular Disease Stroke Strokes 52

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP342-ATP342, February 1, 2025. Background:Previous research has suggested pericarotid fat density to be significantly linked to atherosclerotic plaque components and cerebrovascular events. Baseline demographics and clinical data of our population were extracted from electronic health records.

Plaque 40

Plaque Stenosis Research Stroke 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. IntroductionHigh resolution vessel wall imaging (HR‐VWI) enables accurate visualization of intracranial atherosclerotic plaques. Radiomics can be utilized as an objective quantification method of plaque appearance and shape.

Plaque 40

Plaque Stenosis Stroke Strokes 40

Medical Xpress - Cardiology

DECEMBER 11, 2024

Investigators who previously found that a daily statin pill helps prevent heart attacks and strokes in people with HIV have now discovered a potential mechanism that may help to stabilize plaques and prevent their rupture in blood vessels. The research led by a team from Mass General Brigham is published in JAMA Cardiology.

Heart Attack 79

Heart Attack Heart attacks Plaque Research 79

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP193-AWP193, February 1, 2025. Introduction:Intracranial atherosclerotic disease (ICAD) is a common cause of primary and secondary stroke. Plaques were segmented on PD images from each time point. Mean plaque size at baseline was 20.94mm3. Mean follow-up time of MRI was 11.8

Plaque 40

Plaque Ischemia Stroke Strokes 40

Journal of the American Heart Association

JANUARY 17, 2025

BackgroundIntracranial atherosclerotic stenosis is a leading cause of ischemic stroke and recurrent events due to plaque instability. Highresolution magnetic resonance imaging identifies plaque enhancement as a key marker of instability. After therapy, stenosis decreased from 75.9% (interquartile range, 69.5%84.8%)

Plaque 40

Plaque Stenosis Cholesterol Stroke 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP338-AWP338, February 1, 2025. Introduction:Extracranial carotid artery pathology accounts for 15-20% of ischemic strokes. Eleven plaques were vulnerable in preoperative MRI with VWI. There were 73.3% male patients. of patients had symptomatic disease.

Plaque 40

Plaque Biomarkers Risk Factors Stroke 40

Stroke: Vascular and Interventional Neurology

JUNE 14, 2023

Stroke: Vascular and Interventional Neurology, Volume 3, Issue 6 , November 1, 2023. BackgroundPlaque enhancement after gadolinium contrast administration may assess plaque instability and response to medical therapy. Plaque burden, degree of stenosis, and area degree of stenosis were calculated at baseline and follow‐up.

Plaque 40

Plaque Stenosis Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP176-ATP176, February 1, 2024. Background:High-risk non-stenosing carotid plaque features are emerging as a possible source of embolism in the setting of ESUS.

Plaque 40

Plaque Stenosis Embolism Stroke 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP61-AWMP61, February 1, 2024. Background:Assessing carotid artery plaques in stenosis is crucial for treatment strategies and safety. We investigated the utility of CEST-MRI as a preoperative plaque diagnostic tool.Methods:APT imaging evaluated plaques prior to the procedures.

Plaque 40

Plaque Stenosis Hemorrhage Stroke 40

Stroke Journal

JANUARY 12, 2024

Stroke, Ahead of Print. Incident carotid plaques and their vulnerability were detected by carotid ultrasound at follow-up (2021). Higher sdLDL-C or sdLDL-C/LDL-C ratio, but not LDL-C, was significantly associated with an increased risk of incident carotid plaques. years (SD=0.14). years (SD=0.14).

Plaque 40

Plaque Cholesterol Ultrasound Stenosis 40

Stroke Journal

FEBRUARY 9, 2024

Stroke, Ahead of Print. BACKGROUND:HIV and hepatitis C virus (HCV) are associated with increased risk of carotid artery atherosclerotic plaque and stroke. Plaques were characterized from 6 areas of the right carotid artery. 2.78]) were each associated with higher prevalence of predominantly echogenic plaque.

Plaque 40

Plaque Ultrasound Risk Factors Stroke 40

MIBHS

JANUARY 15, 2025

Inflammation and Plaque Buildup: Smoking damages the endothelium (the inner lining of blood vessels), triggering inflammation. This damage accelerates the formation of plaques, leading to atherosclerosisa condition where arteries narrow and harden, restricting blood flow.

Coronary Artery Bypass Graft 52

Coronary Artery Bypass Graft Blood Clot Blood Pressure Plaque 52

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP23-ATP23, February 1, 2024. Scanning laser ophthalmoscopy (SLO) visualizes two important markers of cognitive dysfunction in the retina, vascular changes and amyloid plaque deposition. Para-arteriolar plaque was higher than para-venular plaque in the entire cohort (p<0.0001).

Plaque 40

Plaque Dementia Stroke Strokes 40

MIBHS

FEBRUARY 15, 2025

Artery Damage : Hypertension damages the inner lining of your arteries, making them less elastic and more prone to plaque buildup. This condition, called atherosclerosis, narrows the arteries, restricting blood flow and increasing the risk of heart attacks and strokes.

Blood Pressure 52

Blood Pressure Hypertension Chest Pain ACE Inhibitor 52

Medical Xpress - Cardiology

FEBRUARY 22, 2024

A recent clinical trial reveals how a daily statin pill may prevent heart attacks and strokes in people with HIV.

Cardiovascular Disease 77

Cardiovascular Disease Heart Attack Heart attacks Plaque 77

Stroke Journal

OCTOBER 31, 2024

Stroke, Ahead of Print. Ischemic stroke is one of the leading causes of disability and mortality worldwide. Thrombosis is the main pathological process of stroke and is therefore an important therapeutic target in stroke prevention.

Stroke 40

Stroke Strokes Thrombosis Plaque 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP226-ATP226, February 1, 2024. Carotid ultrasound results were divided into two groups based on the presence or absence of plaque. Carotid plaque was observed in 1140 (43.5%) subjects and CACS>0 in 1172 (44.7%) subjects. Results:A total of 2620 subjects were enrolled.

Plaque 40

Plaque Coronary Artery Disease Ultrasound Atherosclerosis 40

Journal of the American Heart Association

DECEMBER 20, 2023

years of follow‐up, 385 incident CVD events (159 coronary heart disease and 226 stroke) were documented. During the median 14.2 years 1.76), 1.72 (1.23–2.40), 2.40), and 2.49 (1.69–3.67), 3.67), respectively.

Stenosis 78

Stenosis Cardiovascular Disease Plaque Heart Disease 78

DAIC

JUNE 4, 2024

I am excited about the potential of the FAI-Score biomarker, which has promising prognostic value beyond existing CT-based methods such as plaque, calcium scoring, and CAD-RADS based interpretation." fold higher risk for cardiac mortality and 5.5-fold

Technology 116

Technology Heart Attack Heart attacks Coronary Artery Disease 116

Stroke Journal

JANUARY 21, 2024

Stroke, Volume 55, Issue 2 , Page 311-323, February 1, 2024. Intracranial atherosclerotic disease (ICAD) is one of the most common causes of stroke worldwide. In addition to stroke, ICAD increases the risk of dementia and cognitive decline, magnifying ICAD societal burden.

Stenosis 74

Stenosis Thrombosis Dementia Embolism 74

American College of Cardiology

SEPTEMBER 19, 2024

Is coronary artery calcium (CAC) density by computed tomography (CT) inversely associated with plaque vulnerability and atherosclerotic cardiovascular disease (ASCVD) events (coronary heart disease [CHD] and stroke)?

Plaque 51

Plaque Cardiovascular Disease Heart Disease Stroke 51