Frontiers in Cardiovascular Medicine

APRIL 24, 2024

The early detection of plaques by circulating biomarkers is highly clinically relevant to prevent the occurrence of major complications such as stroke or heart attacks. miRNA expression profiles of serum-derived EVs were obtained by small RNA sequencing and in plaque material simultaneously acquired from patients.

Plaque 52

Plaque Circulation Biomarkers Stenosis 52

DAIC

FEBRUARY 20, 2024

mm (green outline) section thickness show the respective calcified plaque (arrowheads) and coronary stenosis (inset images). The reduced section thickness leads to less calcium blooming and therefore a less severe assessment of percentage of coronary stenosis in this patient. Curved multiplanar reconstructions with 0.6-mm

Coronary Artery Disease 105

Coronary Artery Disease Stenosis Plaque Technology 105

DAIC

FEBRUARY 26, 2025

Coronary computed tomography angiography (CCTA) was a major advancement in CAD diagnostics, helping physicians estimate if a stenosis was significant and requiring intervention. Now Heartflow Plaque Analysis leverages AI to quantify and characterize the amount and type of plaque present in the arteries from a single CCTA scan.

Coronary Artery Disease 59

Coronary Artery Disease Heart Attack Heart attacks Technology 59

DAIC

JANUARY 4, 2024

These key takeaways from the research letter on IVL-facilitated valvuloplasty for severely calcified mitral valve stenosis are published in the Journal of the American College of Cardiology (JACC) Cardiovascular Interventions. We are looking forward to treating patients who have no other options for mitral stenosis diseased valves.”

Heart Valves 119

Heart Valves Bicuspid/Mitral Open-Heart Surgery Stenosis 119

All About Cardiovascular System and Disorders

MAY 22, 2024

About a fifth of all ischemic strokes are attributed to embolization of ruptured atherosclerotic plaque from carotid arterial stenosis. But it has been difficult to predict which person with asymptomatic carotid artery stenosis is likely to progress to symptomatic carotid disease and stroke. J Am Coll Cardiol. 2024.03.389.

Stenosis 52

Stenosis Stroke Strokes Risk Factors 52

Frontiers in Cardiovascular Medicine

JANUARY 24, 2024

Background Although atherosclerosis (AS) can affect multiple vascular beds, previous studies have focused on the analysis of single-site AS plaques. The plaques were then categorized into culprit plaques, non-culprit plaques, and non-event plaques.

Plaque 45

Plaque Stenosis Hemorrhage Atherosclerosis 45

Open Heart

MARCH 8, 2024

Objective Coronary CT angiography (CCTA) permits both qualitative and quantitative analysis of atherosclerotic plaque and may be a suitable risk modifier in assessing patients at intermediate risk of atherosclerotic cardiovascular disease. 47 (57%) patients had mixed plaque, which was predictive of MACE (OR 4.68 (95% CI 1.19

Plaque 52

Plaque Stenosis Cardiovascular Disease Stroke 52

Ken Grauer, MD

FEBRUARY 3, 2024

BUT — Cardiac catheterization done a little later did not reveal any significant stenosis. Despite the absence of significant coronary stenosis on her post-arrest cath — the ECG in Figure-1 is clearly diagnostic of an extensive anterolateral STEMI ( presumably from acute LAD [ L eft A nterior D escending ] coronary artery occlusion).

Blog 163

Blog Cardiac Arrest STEMI Plaque 163

Journal of the American Heart Association

JANUARY 17, 2025

BackgroundIntracranial atherosclerotic stenosis is a leading cause of ischemic stroke and recurrent events due to plaque instability. Highresolution magnetic resonance imaging identifies plaque enhancement as a key marker of instability. After therapy, stenosis decreased from 75.9% (interquartile range, 69.5%84.8%)

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Plaque Stenosis Cholesterol Stroke 40

Stroke Journal

JANUARY 30, 2025

However, few reports have discussed CNs in the context of carotid artery stenosis. We performed pathological analysis of plaque characteristics in carotid arteries and compared with patient characteristics.Results:Of the 508 specimens, 462 (90.9%) were from male patients and mean degree of stenosis was 73.816.4%.

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Stenosis Plaque Stroke Strokes 40

Stroke: Vascular and Interventional Neurology

JUNE 14, 2023

BackgroundPlaque enhancement after gadolinium contrast administration may assess plaque instability and response to medical therapy. Plaque burden, degree of stenosis, and area degree of stenosis were calculated at baseline and follow‐up. Stroke: Vascular and Interventional Neurology, Volume 3, Issue 6 , November 1, 2023.

Plaque 40

Plaque Stenosis Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Background:Assessing carotid artery plaques in stenosis is crucial for treatment strategies and safety. This study explores the correlation between APT imaging and histopathological findings of carotid artery plaques in 34 consecutive patients who had carotid endarterectomy. E-04) and Group B (APT signal values < 1.90

Plaque 40

Plaque Stenosis Hemorrhage Stroke 40

Stroke Journal

FEBRUARY 1, 2024

Ipsilateral and contralateral carotid artery plaque features were compared, then the carotid artery plaque characteristics on the infarct side were correlated with the infarct pattern.Results:the mean age of subjects included was 68 years old, 79.6% of them were male. 0.15), larger wall area (0.50±0.19 0.23), all p values<0.05.

Plaque 40

Plaque Atherosclerosis Stroke Strokes 40

Stroke Journal

JANUARY 30, 2025

Background and Purpose:We aimed to investigate the effects of evolocumab, a proprotein convertase subtilisin/kexin type-9 inhibitor for intensive lipid-lowering, on intracranial atherosclerotic stenosis (ICAS).Methods:From The primary outcomes were the percentage change in plaque burden and plaque response (plaque regression >5%) rate.

Stenosis 40

Stenosis Plaque Outcomes Stroke 40

Stroke Journal

JANUARY 30, 2025

Background:Previous research has suggested pericarotid fat density to be significantly linked to atherosclerotic plaque components and cerebrovascular events. Inflammatory markers within the plaques are critical in the pathogenesis and progression of carotid artery disease.

Plaque 40

Plaque Stenosis Research Stroke 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

IntroductionHigh resolution vessel wall imaging (HR‐VWI) enables accurate visualization of intracranial atherosclerotic plaques. Radiomics can be utilized as an objective quantification method of plaque appearance and shape. Culprit plaques in the vascular territory of the stroke were identified.

Plaque 40

Plaque Stenosis Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Background:High-risk non-stenosing carotid plaque features are emerging as a possible source of embolism in the setting of ESUS. We utilized Fisher’s exact test to compare the frequencies of reporting each plaque characteristic.Results:We analyzed 152 CTA reports in depth.

Plaque 40

Plaque Embolism Stenosis Stroke 40

Stroke Journal

JANUARY 30, 2025

Introduction:Nonstenotic carotid plaque is found in some patients with otherwise cryptogenic stroke (CS) but also in normal individuals and patients with stroke of known cause (KS). Overall, nonstenotic carotid stenosis ipsilateral to ischemic stroke was found in 33.5% (255/761) CS patients vs 19.2% (152/790) KS patients.

Plaque 40

Plaque Stroke Strokes Ultrasound 40

DAIC

JUNE 4, 2024

The Neuroguard Integrated Embolic Protection (IEP) system is an experimental treatment for carotid artery stenosis, also known as carotid artery disease, a condition in which fatty-waxy deposits known as plaque builds up and blocks the normal flow of blood in the large arteries on either side of the neck.

Stents 111

Stents Stent Research Stroke 111

DAIC

JUNE 10, 2024

According to the writing group – co-led by SCCT Past President Koen Nieman , MD, PhD, MSCCT – well-described semi-quantitative scores and classifications are primarily based on visual interpretation or through categories of obstructive severity rather than exact percentage stenosis measurements.

Document 104

Document Coronary Artery Disease Stenosis Atherosclerosis 104

Dr. Smith's ECG Blog

NOVEMBER 15, 2023

MINOCA may be due to: coronary spasm, coronary microvascular dysfunction, plaque disruption, spontaneous coronary thrombosis/emboli , and coronary dissection; myocardial disorders, including myocarditis, takotsubo cardiomyopathy, and other cardiomyopathies. There may be a chronic tight stenosis and a non-obstructed lesion that thrombosed.

Coronary Angiogram 110

Coronary Angiogram Plaque Thrombosis STEMI 110

Stroke Journal

JUNE 26, 2024

Asymptomatic high-grade carotid stenosis is an important therapeutic target for stroke prevention. Features like intraplaque hemorrhage on MRI and echolucency on B-mode ultrasonography can identify patients at higher risk of stroke with asymptomatic stenosis.

Stenosis 40

Stenosis Stents Stent Atherosclerosis 40

EMS 12-Lead

APRIL 9, 2024

The LM has an irregular 30% distal stenosis, followed by an 80% ostial LAD stenosis, and total occlusion of the LAD proximally with TIMI grade 1 flow in the distal vessel. The LCX demonstrates an ostial 80% stenosis prior to the bifurcation of a large OM artery. A large Diagonal artery has subtotal occlusion proximally.

Ischemia 116

Ischemia Stenosis Chest Pain Coronary Artery Disease 116

Stroke Journal

FEBRUARY 1, 2024

Introduction:A new Plaque-RADS classification (I-IV) is proposed to categorize the degree of carotid plaque instability and risk of embolic ischemic stroke. Carotid total plaque thickness and ulceration were scored by a neuroradiologist blinded to stroke side. N=188 plaques) met criteria. N=188 plaques) met criteria.

Plaque 40

Plaque Embolism Stroke Strokes 40

Stroke Journal

JANUARY 30, 2025

The bovine anatomical variation may alter the blood flow dynamics, potentially contributing to the formation and progression of carotid plaques. CTAs were reviewed to assess the carotid stenosis and the anatomy of the aortic arch. N=16, 36.4%; p=0.030). vs. 70.0% [50.0-95.0]; 95.0]; p=0.030)(Figure 3).Conclusions:The

Anatomy 40

Anatomy Stenosis Aortic Plaque 40

Stroke Journal

JANUARY 12, 2024

Incident carotid plaques and their vulnerability were detected by carotid ultrasound at follow-up (2021). Higher sdLDL-C or sdLDL-C/LDL-C ratio, but not LDL-C, was significantly associated with an increased risk of incident carotid plaques. years (SD=0.14). years (SD=0.14). 9.90];P=0.027;Pfor linear trend=0.025).

Plaque 40

Plaque Cholesterol Ultrasound Risk Factors 40

Stroke Journal

JANUARY 21, 2024

The risk of stroke recurrence among patients with ICAD-related stroke is the highest among those with confirmed stroke and stenosis ≥70%. In fact, the 1-year recurrent stroke rate of >20% among those with stenosis >70% is one of the highest rates among common causes of stroke.

Stenosis 74

Stenosis Thrombosis Dementia Embolism 74

Frontiers in Cardiovascular Medicine

FEBRUARY 21, 2024

Materials and methods This retrospective, institutional-review board approved study included consecutive patients with calcified coronary artery plaques undergoing CCTA with PCD-CT and invasive coronary angiography between July and December 2022. Virtual monoenergetic images (VMI) and VNCa images were reconstructed. 68, ICC: 94 and 1%, p  = .07,

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Plaque Stenosis 69

Frontiers in Cardiovascular Medicine

FEBRUARY 8, 2024

Invasive plaque characterization of the SFA was performed by intravascular imaging using optical coherence tomography. Histological analysis of plaque specimens was performed after directional atherectomy. cm vs. 0.23 ± 0.11 cm; cm; 1.77 ± 0.19 vs. 1.57 ± 0.15; p -value <0.05). cm vs. 0.23 ± 0.11 cm; cm; 1.77 ± 0.19

Plaque 59

Plaque Stenosis 59

DAIC

JUNE 18, 2024

The breakthrough designation, according to the Milpitas, CA-based technology company, is for an indication to improve coronary luminal diameter, restore hemodynamic modulation, and reduce plaque progression in patients with symptomatic ischemic heart disease due to discrete de novo native coronary artery lesions. of the U.S. population.

Coronary Artery Disease 105

Coronary Artery Disease Technology Stents Stent 105

DAIC

NOVEMBER 8, 2024

The Philips laser catheter integrates two critical PAD treatments into a single device, significantly simplifying the treatment workflow – atherectomy to remove atherosclerotic plaque from the internal surface of an artery, and intravascular lithotripsy to modify calcium deposits within the artery or disrupt calcium deposits in the artery wall.

Innovation 52

Innovation Peripheral Arterial Disease Technology Ultrasound 52

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

3% sodium alginate solution was cast into a stenosis mold and crosslinked in a 40% calcium chloride. The deformable gel constituted an 8mm long replaceable stenotic segment at the level of M1‐MCA simulating an atherosclerotic plaque with a 0.5mm internal diameter. An initial stenosis flow rate was registered with a value of 8.5 ± 5.33

Stenosis 40

Stenosis Angioplasty Anatomy Plaque 40

Dr. Smith's ECG Blog

SEPTEMBER 22, 2023

A healthy young man would be expected to have a troponin that is undetectable (less than 3 ng/L) The patient went to the cath lab: --Ruptured plaque in the distal LAD --Diffuse coronary artery disease is noted in LAD branch vessels and a small LPL branch -- LAD is a large-caliber vessel that wraps around the apex (this explains the STE in inferior (..)

STEMI 132

STEMI Stenosis Plaque Chest Pain 132

DAIC

JANUARY 17, 2024

The application of AI technology in the diagnosis of cardiovascular diseases using coronary CT angiography (CCTA) has gradually deepened, and efficient and intelligent methods are optimizing and reshaping the clinical diagnosis pathways, including optimization of image quality, fully automated calculation of calcification score, coronary stenosis, (..)

Technology 111

Technology Coronary Artery Disease Cardiovascular Disease Cardiovascular Imaging 111

All About Cardiovascular System and Disorders

APRIL 10, 2024

IVUS Measurements Measurements include the measurement of lumen, plaque, calcium, remodeling, stent length and volumetric measurements. Plaque morphology assessment with IVUS Plaque morphology can be assessed in terms of its geometry and echogenicity. A vulnerable plaque and a plaque with ulceration or rupture can also be found.

Ultrasound 52

Ultrasound Plaque Stents Stent 52

DAIC

FEBRUARY 13, 2024

With Plaque Features Associated with False Positives. Coronary CTA With AI-QCT Interpretation: Comparison With Myocardial Perfusion Imaging for Detection of Obstructive Stenosis Using Invasive Angiography as Reference Standard. Presented at the European Association of Cardiovascular Imaging: Late Breaking Clinical Research and Trials.

Coronary Artery Disease 103

Coronary Artery Disease Ischemia Atherosclerosis Cardiovascular Imaging 103

DAIC

FEBRUARY 3, 2025

Lp(a) is emerging as an important, yet under-recognized, potential risk factor for cardiovascular disease due to its ability to promote the development of plaques within artery walls, clot formation and aortic valve calcification. 2022 Aug, 80 (9) 934946 Kronenberg F.

Cardiovascular Disease 52

Cardiovascular Disease Aortic valve Innovation Biomarkers 52