Med Page Today

MARCH 5, 2025

(MedPage Today) -- For select risk-enhanced individuals at intermediate risk of coronary artery disease (CAD), researchers found a way to implement coronary artery calcium (CAC) scores and primary prevention statins together to slow the progression.

Coronary Artery Disease 98

Coronary Artery Disease Plaque Research 98

Science Daily - Heart Disease

NOVEMBER 13, 2024

Researchers have identified a new target to treat atherosclerosis, a condition where plaque clogs arteries and causes major cardiac issues, including stroke and heart attack.

Cardiovascular Disease 112

Cardiovascular Disease Heart attacks Heart Attack Plaque 112

Science Daily - Stroke

FEBRUARY 25, 2025

CD8+ T cells accumulate in atherosclerotic plaques. Researchers identify a crucial signaling pathway -- with therapeutic potential.

Plaque 52

Plaque Atherosclerosis Research 52

Frontiers in Cardiovascular Medicine

APRIL 10, 2025

Plaque characterization agreement was assessed using Cohens .ResultsThe Plaque characterization exhibited high agreement (calcified: =0.82; non-calcified: =0.78; mixed: =0.75).ConclusionECG-less A modified ECG-less protocol (Group A2, n=30) was implemented to optimize radiation dose. vs. 1.901.41mSv, p 0.05). and per-patient 94.4%/50%

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Coronary Artery Disease Plaque Electrocardiogram Stenosis 52

CTVS

OCTOBER 30, 2024

Research shows that in recent years almost half of all adults in the United States have been living with heart disease, one of the most prominent forms of vascular disease. Vascular disease affects the body’s vast network of blood vessels, veins and arteries.

Aneurysm 52

Aneurysm Plaque Atherosclerosis Heart Disease 52

Medical Xpress - Cardiology

MAY 16, 2024

Exercising, even at extreme levels, does not accelerate the calcium buildup in arteries more often seen in marathoners and fitness enthusiasts, according to new research published in JAMA Cardiology from UT Southwestern and the Cooper Institute.

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Exercise Plaque Research 85

Science Daily - Heart Disease

MAY 7, 2024

Researchers have discovered a protein marker to help identify cells able to repopulate in patients with damaged blood vessels.

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Coronary Artery Disease Biomarkers Heart attacks Heart Attack 103

Medical Xpress - Cardiology

DECEMBER 12, 2023

University of Virginia School of Medicine researchers have created an "atlas of atherosclerosis" that reveals, at the level of individual cells, critical processes responsible for forming the harmful plaque buildup that causes heart attacks, strokes, and coronary artery disease.

Heart attacks 105

Heart attacks Heart Attack Atherosclerosis Coronary Artery Disease 105

Medical Xpress - Cardiology

NOVEMBER 13, 2024

Researchers at Case Western Reserve University have identified a new target to treat atherosclerosis, a condition where plaque clogs arteries and causes major cardiac issues, including stroke and heart attack.

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Atherosclerosis Heart attacks Heart Attack Plaque 89

Dr. Paddy Barrett

DECEMBER 19, 2023

You cannot eliminate the plaque entirely, but multiple clinical trials have shown plaque regression using high-intensity cholesterol-lowering treatments, which I have discussed previously. All of these parameters are important and need to be considered when evaluating plaque regression. REVERSAL Investigators.

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Coronary Artery Disease Plaque Exercise Heart attacks 106

Medical Xpress - Cardiology

APRIL 7, 2025

The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, in collaboration with researchers across multiple institutions, has published a new study that challenges the long-held belief that high cholesterol correlates and even directly causes coronary artery disease, or plaque buildup in the arteries in metabolically healthy (..)

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Cholesterol Research Coronary Artery Disease Diet 43

HCPLive

FEBRUARY 18, 2024

During this segment of his interview, Bissonnette discussed safety data on JNJ-2113 for patients with plaque psoriasis and later went into future research topics.

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Research Plaque 52

Cardiovascular Diabetology

DECEMBER 17, 2024

The impact of AIP on plaque characteristics is not fully understood. Atherogenic index of plasma (AIP) has been recommended as a marker of plasma atherogenicity.

Plaque 52

Plaque Research 52

DAIC

APRIL 11, 2024

The study, called IVUS-DCB, is the first randomized controlled trial to demonstrate the clinical benefits of using IVUS in angioplasty procedures for peripheral artery disease (PAD), a condition in which plaque builds up in arteries in the legs. Half were randomly assigned to receive IVUS plus angiography and half received angiography alone.

Peripheral Arterial Disease 116

Peripheral Arterial Disease Ultrasound Angioplasty Plaque 116

Stroke Journal

JANUARY 30, 2025

Background:Previous research has suggested pericarotid fat density to be significantly linked to atherosclerotic plaque components and cerebrovascular events. Inflammatory markers within the plaques are critical in the pathogenesis and progression of carotid artery disease.

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Plaque Stenosis Research Strokes 40

Medical Xpress - Cardiology

JULY 2, 2024

Vascular plaque. It starts with inflammation. Perhaps your blood pressure has been a little too high for a little too long, putting strain on your blood vessels.

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Heart attacks Heart Attack Cholesterol Blood Pressure 52

Medical Xpress - Cardiology

DECEMBER 11, 2024

Investigators who previously found that a daily statin pill helps prevent heart attacks and strokes in people with HIV have now discovered a potential mechanism that may help to stabilize plaques and prevent their rupture in blood vessels. The research led by a team from Mass General Brigham is published in JAMA Cardiology.

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Heart attacks Heart Attack Plaque Research 77

DAIC

FEBRUARY 20, 2024

mm (green outline) section thickness show the respective calcified plaque (arrowheads) and coronary stenosis (inset images). However, its diagnostic value is limited in patients with severe calcifications, or calcium buildup in the plaque of the coronary arteries. Curved multiplanar reconstructions with 0.6-mm mm (yellow outline), 0.4-mm

Coronary Artery Disease 105

Coronary Artery Disease Stenosis Plaque Technology 105

Science Daily - Stroke

JULY 12, 2023

In a major study, researchers have discovered a link between the levels of certain bacteria living in the gut and coronary atherosclerotic plaques. Such atherosclerotic plaques, which are formed by the build-up of fatty and cholesterol deposits, constitute a major cause of heart attacks.

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Heart attacks Heart Attack Plaque Cholesterol 69

DAIC

JANUARY 4, 2024

These key takeaways from the research letter on IVL-facilitated valvuloplasty for severely calcified mitral valve stenosis are published in the Journal of the American College of Cardiology (JACC) Cardiovascular Interventions. “We The research letter’s lead author, Gennaro Giustino, M.D.,

Heart Valves 119

Heart Valves Bicuspid/Mitral Open-Heart Surgery Stenosis 119

DAIC

JULY 23, 2024

First runner-up for the YIA is Seokhun Yang, MD , of Seoul National University Hospital, for his abstract, “Prognostic Implications Of Coronary CT Angiography-derived Plaque And Hemodynamic Features On Acute Coronary Syndrome Across Varying Time Intervals: Emerald-ii Study.” and the Ma Family, who provided a $5,000 case prize for the winner.

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Chest Pain Plaque Coronary Artery Disease Ischemia 105

DAIC

JUNE 10, 2024

Published in the Journal of Cardiovascular Computed Tomography (JCCT), “Standards for Quantitative Assessments by Coronary Computed Tomography Angiography (CCTA)” provides a framework for terminology, methodology and reporting of quantitative CCTA analyses to create a common language for both clinicians and researchers.

Document 104

Document Coronary Artery Disease Stenosis Plaque 104

Frontiers in Cardiovascular Medicine

FEBRUARY 12, 2025

This study investigates the regulatory functions of distinct cell populations in AS pathogenesis, focusing on the interaction between vascular smooth muscle cell (VSMC)-derived ITLN1+ foam cells and SPP1+ FABP5+ macrophages.MethodsWe employed single-cell RNA sequencing to characterize cell populations within AS plaques.

Atherosclerosis 40

Atherosclerosis Plaque Research 40

Medical Xpress - Cardiology

FEBRUARY 1, 2024

A research team based at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) in Madrid and Aarhus University in Denmark has identified an important mechanism that can result in the regression, or shrinkage, of atherosclerotic plaques.

Cholesterol 66

Cholesterol Plaque Research 66

DAIC

JUNE 4, 2024

I am excited about the potential of the FAI-Score biomarker, which has promising prognostic value beyond existing CT-based methods such as plaque, calcium scoring, and CAD-RADS based interpretation." fold higher risk for cardiac mortality and 5.5-fold The CaRi-Heart technology is in clinical use in the UK, European Union, and Australia.

Technology 116

Technology Heart attacks Heart Attack Coronary Artery Disease 116

Frontiers in Cardiovascular Medicine

MARCH 14, 2025

PR was defined as an outer vessel diameter at least 10% greater than the average diameter of the segments immediately proximal and distal to the plaque. MethodsWe analyzed data from 1,324 patients who underwent both CTCS and CT angiography.

Coronary Artery Disease 52

Coronary Artery Disease Plaque Innovation Research 52

Frontiers in Cardiovascular Medicine

FEBRUARY 23, 2025

Numerous previous studies have shown that cardiac rehabilitation can inhibit the progression of atherosclerotic plaques in patients after coronary intervention, effectively controlling patients' clinical symptoms and improving their quality of life.

Cardiac Rehabilitation 52

Cardiac Rehabilitation Chronic Disease Quality of Life Public Health 52

Cardiovascular Diabetology

JULY 7, 2024

Metabolism is increasingly recognized as a key regulator of the function and phenotype of the primary cellular constituents of the atherosclerotic vascular wall, including endothelial cells, smooth muscle cell.

Plaque 52

Plaque Research 52

Science Daily - Heart Disease

APRIL 30, 2024

Researchers have discovered that the smooth muscle cells that line the arteries of people with atherosclerosis can change into new cell types and develop traits similar to cancer that worsen the disease.

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Atherosclerosis Cancer Peripheral Arterial Disease Coronary Artery Disease 59

HCPLive

APRIL 13, 2025

In this interview, Lawrence Eichenfield, MD, speaks on his teams recent research on icotrokinra for patients with moderate-to-severe plaque psoriasis.

Plaque 40

Plaque Research 40

Dr. Smith's ECG Blog

NOVEMBER 15, 2023

MINOCA may be due to: coronary spasm, coronary microvascular dysfunction, plaque disruption, spontaneous coronary thrombosis/emboli , and coronary dissection; myocardial disorders, including myocarditis, takotsubo cardiomyopathy, and other cardiomyopathies. There may be a chronic tight stenosis and a non-obstructed lesion that thrombosed.

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Coronary Angiogram Plaque Thrombosis STEMI 109

DAIC

JANUARY 17, 2024

This review systematically introduces the common AI techniques in the field of cardiovascular computed tomography (CT), summarizes the current research and application progress of AI in cardiovascular CT, and provides its future perspectives.

Technology 111

Technology Coronary Artery Disease Cardiovascular Disease Cardiovascular Imaging 111

Medical Xpress - Cardiology

OCTOBER 16, 2024

New research published in the Journal of Stroke and Cerebrovascular Diseases confirms that strokes thought to happen in older adults are possible in the younger (defined as 18–50 years old) population.

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Blood Clot Cerebrovascular Disease Strokes Stroke 52

Cardiovascular Diabetology

JULY 21, 2024

Sodium–Glucose Cotransporter-2 Inhibitor (SGLT2i) is a novel oral drug for treating type 2 diabetes mellitus (T2DM) with demonstrated cardiovascular benefits. Previous studies in apolipoprotein E knockout mice.

Plaque 59

Plaque Diabetes Research 59

DAIC

JANUARY 9, 2024

It provides detailed information about the vessel wall, plaque composition, and blood flow characteristics, enabling more accurate diagnosis and treatment planning. They also emphasized the need for further research and evidence to support the integration of IVUS into routine clinical practice. Tam, MD, MBA, FSIR.

Peripheral Arterial Disease 105

Peripheral Arterial Disease Ultrasound Angioplasty Interventional Cardiology 105

DAIC

APRIL 8, 2024

The study focused on patients who underwent PCI for acute coronary syndromes (ACS)—life-threatening conditions which include heart attacks and chest pain caused by decreased blood flow to the heart—with stents containing drugs to prevent further plaque buildup.

Heart attacks 111

Heart attacks Heart Attack Stents Stent 111

Medical Xpress - Cardiology

FEBRUARY 25, 2025

CD8+ T cells accumulate in atherosclerotic plaques. LMU researchers identify a crucial signaling pathwaywith therapeutic potential.

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Atherosclerosis Plaque Research 40