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Very high LDL no impact on plaque progression

Dr. Malcolm Kendrick

10th December 2023 A very important study – please watch Very high low density lipoprotein levels with no impact on plaque progression I interrupt my series on what is wrong with the health service to bring you breaking news. He states that five years is more than sufficient to detect any difference in plaque progression.

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Lipoprotein(a) and Long-Term Plaque Progression, Low-Density Plaque, and Pericoronary Inflammation

JAMA Cardiology

This study investigates the impact of lipoprotein(a) levels on long-term coronary artery plaque progression, high-risk plaque, and pericoronary adipose tissue inflammation.

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What have we learnt from histology about the efficacy of coronary imaging modalities in assessing plaque composition?

Frontiers in Cardiovascular Medicine

Intravascular imaging was introduced for this purpose 40 years ago enabling for the first time in vivo plaque characterization.

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Atherosclerotic plaque stabilization and regression: a review of clinical evidence

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 04 January 2024; doi:10.1038/s41569-023-00979-8 In this Review, Sarraju and Nissen summarize the clinical trial evidence for coronary atherosclerotic plaque stabilization and regression with plasma LDL-cholesterol-lowering therapy and other treatments.

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Early Win for Preemptive Stents on Vulnerable Coronary Plaque

Med Page Today

(MedPage Today) -- ATLANTA -- The concept of using stents to seal off non-flow-limiting vulnerable plaques, before they have a chance to rupture, worked out in the first major trial testing this provocative idea. Compared with standard medical.

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Cholesterol may not be the only lipid involved in trans fat-driven cardiovascular disease

Medical Xpress - Cardiology

Excess cholesterol is known to form artery-clogging plaques that can lead to stroke, arterial disease, heart attack, and more, making it the focus of many heart health campaigns.

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Analysis and validation of biomarkers and immune cell infiltration profiles in unstable coronary atherosclerotic plaques using bioinformatics and machine learning

Frontiers in Cardiovascular Medicine

IntroductionDecreased stability of coronary atherosclerotic plaques correlates with a heightened risk of acute coronary syndrome (ACS). Thus, early diagnosis and treatment of unstable plaques are imperative in averting adverse cardiovascular events.

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