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10th December 2023 A very important study – please watch Very high low density lipoprotein levels with no impact on plaque progression I interrupt my series on what is wrong with the health service to bring you breaking news. He states that five years is more than sufficient to detect any difference in plaque progression.
This study investigates the impact of lipoprotein(a) levels on long-term coronary artery plaque progression, high-risk plaque, and pericoronary adipose tissue inflammation.
Nature Reviews Cardiology, Published online: 04 January 2024; doi:10.1038/s41569-023-00979-8 In this Review, Sarraju and Nissen summarize the clinical trial evidence for coronary atherosclerotic plaque stabilization and regression with plasma LDL-cholesterol-lowering therapy and other treatments.
(MedPage Today) -- ATLANTA -- The concept of using stents to seal off non-flow-limiting vulnerable plaques, before they have a chance to rupture, worked out in the first major trial testing this provocative idea. Compared with standard medical.
Excess cholesterol is known to form artery-clogging plaques that can lead to stroke, arterial disease, heart attack, and more, making it the focus of many heart health campaigns.
IntroductionDecreased stability of coronary atherosclerotic plaques correlates with a heightened risk of acute coronary syndrome (ACS). Thus, early diagnosis and treatment of unstable plaques are imperative in averting adverse cardiovascular events.
milla1cf Tue, 06/04/2024 - 20:54 June 4, 2024 — HeartFlow, a leader in cardiovascular healthcare technology, is pleased to announce a key Medicare policy development, which should allow for future expanded patient access to their Plaque Analysis product.
a leader in non-invasive artificial intelligence (AI) heart care solutions, introduced the next generation HeartFlow Plaque Analysis with an interactive experience. Having access to a patient’s whole coronary picture, with both quantified plaque and physiology, is a game changer as a clinician. F.A.C.C.
The most accurate way (But not the only way) to answer this question is whether or not you have plaque in your coronary arteries. If you already have plaque, your risk of event an event goes up proportional to the amount of plaque you have 2. In this scenario, your risk of a heart attack over the next 10 years is well under 2%.
These new findings suggest that people with high-risk plaques that are likely to rupture could benefit from the procedure as a pre-emptive measure rather than waiting for a heart attack or other severe reduction in blood flow to occur. During PCI, an operator inserts a stent into a blocked artery through a catheter in the groin or arm.
In this 6-month randomized controlled study, twice-weekly HIIT reduced coronary plaque volume, increased aerobic fitness, and improved body composition in adults with stable heart disease, suggesting benefits for cardiovascular disease progression. Does this greater plaque presence put athletes at a greater risk of CVD events?
Recent research has illuminated the role of total coronary atherosclerotic plaque activity across the entire coronary arterial tree in predicting patient-level clinical outcomes. Vessel-level coronary atherosclerotic plaque activity was assessed using coronary 18 F-sodium fluoride positron emission tomography (PET). 3.72; P = 0.013).
Atherosclerosisa key driver of cardiovascular disease (CVD)continues to be a significant global health issue. While advances in treatment have reduced mortality in some regions, the atherosclerosis prevention remains challenging.
The registry will collect multi-site, real-world information on how the Plaque Analysis product provides enhanced patient insights, empowering physicians and helping to inform their medical management decisions for patients with suspected coronary artery disease (CAD). 2 “Data from the DECODE study shows the value of using Plaque Analysis.
Researchers show that genetic traits influence the cellular composition of atherosclerotic plaques, which over time will affect the risk of such lesions to cause a stroke or heart attack. The new knowledge can be used to improve the risk assessment and treatment of patients with atherosclerosis in the future.
The definition of a high-risk plaque should be expanded beyond the traditional focus on plaque rupture and thin-cap fibroatheroma in the setting of acute coronary syndromes (ACS), according to a new JACC: Cardiovascular Imaging Position Statement.
Atherosclerosis, or the buildup of plaque in the arteries, develops when low-density lipoprotein cholesterol (LDL-C) enters the blood vessel walls through dysfunctional endothelial cells (EC), leading to the formation of plaques.
In a new study published in the European Heart Journal, researchers at Karolinska Institutet show that genetic traits influence the cellular composition of atherosclerotic plaques, which over time will affect the risk of such lesions for causing a stroke or heart attack.
BACKGROUND:Recently, it was reported that noncalcified plaque (NCP) volume was an independent predictor for cardiac events. Plaque volume was measured by computed tomography angiography, plaque vulnerability by optical coherence tomography, and the level of coronary inflammation by PCAT attenuation. versus 75.9%;P<0.001),
Aging is known to be a risk factor for the biological changes that create the dangerous buildup of plaque in arteries called atherosclerosis, and aging also induces a buildup of memory CD8 T cells, a type of immune cell, in mice and humans.
Are high-risk plaque (HRP) features on coronary computed tomography angiography (CTA) associated with vulnerable plaque on optical coherence tomography (OCT)?
The goal of the PREVENT trial was to compare the safety and efficacy of medical therapy along with focal preventive PCI of non-flow-limiting vulnerable plaque compared with medical therapy alone.
Researchers have developed a new catheter-based device that combines two powerful optical techniques to image the dangerous plaques that can build up inside the arteries that supply blood to the heart.
Nature Reviews Cardiology, Published online: 02 January 2025; doi:10.1038/s41569-024-01110-1 In this Review, Dey and colleagues explore the pathobiology of coronary atherosclerotic plaques and perivascular adipose tissue, describe their phenotyping with computed tomography coronary angiography, and discuss potential future applications in clinical (..)
In this systematic review and meta-analysis, the investigators highlighted topical roflumilast’s success in clinical milestones such as IGA and PASI score success.
(MedPage Today) -- It was common for tiny plastic particles from the environment to infiltrate people's vascular lesions, foreshadowing future cardiovascular disease in patients who underwent carotid endarterectomy, an observational study showed.
The CaRi-Plaque technology supports non-invasive analysis of coronary anatomy and pathology from routine coronary computed tomography angiography (CCTA) scans to determine the presence, extent and severity of coronary plaques and luminal stenosis (narrowing of arteries). But with AI, we can change that.
Metal exposure from environmental pollution is associated with increased buildup of calcium in the coronary arteries at a level that is comparable to traditional risk factors like smoking and diabetes, according to a study by Columbia University Mailman School of Public Health.
A unique strength of coronary computed tomography angiography (CCTA) is the ability to noninvasively detect nonobstructive and obstructive coronary plaque.
PCI performed preventively in patients with high-risk vulnerable plaques was found to be superior to optimal medical therapy alone in preventing a serious cardiac event, according to the results of the PREVENT trial, the largest study on preventive PCI to date, presented during a Late-Breaking Clinical Trial session during ACC.24
(MedPage Today) -- For select risk-enhanced individuals at intermediate risk of coronary artery disease (CAD), researchers found a way to implement coronary artery calcium (CAC) scores and primary prevention statins together to slow the progression.
Nature Reviews Cardiology, Published online: 23 January 2024; doi:10.1038/s41569-024-00993-4 Anti-inflammatory therapy involving IL-1β inhibition might reduce the risk of cardiovascular events in individuals with clonal haematopoiesis by increasing the number of fibroblast-like cells in the fibrous cap region of atherosclerotic plaques, thereby stabilizing (..)
A cardiac CT is a low-dose CT scan of your heart that assesses whether or not you have plaque in your coronary arteries and, if so, how much. In general, the more plaque you have, the higher your risk of a heart attack over the next 10 years.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is associated with more rapid progression of coronary artery lesion-based plaque volume, according to a study published online Feb. 4 in Radiology.
(MedPage Today) -- TTHealthWatch is a weekly podcast from Texas Tech. In it, Elizabeth Tracey, director of electronic media for Johns Hopkins Medicine in Baltimore, and Rick Lange, MD, president of the Texas Tech University Health Sciences Center.
Nature Reviews Cardiology, Published online: 18 March 2024; doi:10.1038/s41569-024-01015-z In patients with carotid artery disease, the presence of microplastics and nanoplastics in the carotid plaque is associated with an increased risk of death or major cardiovascular events compared with patients in whom microplastics and nanoplastics were not detected. (..)
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