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Revolutionary Genomic Study Sheds Light on Immune Microenvironment in Transplanted Pediatric Hearts

DAIC

© THE TEXAS HEART INSTITUTE 2024 milla1cf Tue, 02/13/2024 - 17:56 February 13, 2024 — Pediatric heart transplantation has long been hailed as a life-saving intervention for children suffering from end-stage heart failure. This helps us gain a comprehensive understanding of the immune response dynamics within transplanted hearts."

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Cancer therapy–related salivary dysfunction

Journal of Clinical Investigation - Cardiology

We discuss salivary gland anatomy and physiology to understand how anticancer therapies such as chemotherapy, bone marrow transplantation, immunotherapy, and radiation therapy impair salivary function. Consequently, changes in salivary function can profoundly impair quality of life for cancer patients.

Cancer 96
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Advanced hemodynamics for prognostication in heart failure: the pursuit of the patient-specific tipping point

Frontiers in Cardiovascular Medicine

Methods Here, a mathematical and physiological framework to define the patient-specific tipping point of myocardial energetics is defined. A novel hemodynamic parameter known as the myocardial performance score (MPS), a marker of power and efficiency, is introduced that allows for the objective assessment of the physiological tipping point.

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Gut microbiota: a potential new regulator of hypertension

Frontiers in Cardiovascular Medicine

We provide a summary of the composition and physiological role of gut microbiota. Finally, we review various regimens for better-controlling hypertension from the diet, exercise, drugs, antibiotics, probiotics, and fecal transplantation perspectives.

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A tale of two hearts

The British Journal of Cardiology

A 74-year-old man with a heterotopic heart transplant experienced alternating episodes of sustained native heart ventricular tachycardia and prolonged asystole. The unique physiology in such patients lends itself to numerous clinical considerations that would otherwise be routine management for most.

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Transcatheter Palliation With Pulmonary Artery Flow Restrictors in Neonates With Congenital Heart Disease: Feasibility, Outcomes, and Comparison With a Historical Hybrid Stage 1 Cohort

Circulation: Cardiovascular Interventions

3.3]) underwent a PFR procedure; 15 (88%) had single ventricle physiology; 15 (88%) were high-risk surgical candidates. Cox regression was used to evaluate the association between palliation strategy and 6-month mortality.Results:From 2021 to 2023, 17 patients (median age, 4 days; interquartile range [IQR], 2–8; median weight, 2.5

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The Thoracic Surgery Foundation Awards Inaugural International Fellowships

Society of Thoracic Surgeons - Technology

With her fellowship, Dr. Fiedler plans to learn skills and administrative approaches that will help her expand the heart transplant program at UW-Madison, where she currently serves as associate director of heart transplantation and mechanical circulatory support. For more information, visit eacts.org.