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Anti-platelet agents inhibit platelet adhesion and aggregation on glass surface under physiological flow conditions: Toward a microfluidic platelet functional assay without additional adhesion protein modification

Journal of Cardiovascular Pharmacology

Abstract: As the pathogenesis of arterial thrombosis often includes platelet adhesion and aggregation, antiplatelet agents are commonly used to prevent thromboembolic events. As the pathogenesis of arterial thrombosis often includes platelet adhesion and aggregation, antiplatelet agents are commonly used to prevent thromboembolic events.

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Factor XI and XIa inhibition: a new approach to anticoagulant therapy

The British Journal of Cardiology

The prospect of uncoupling the management of thrombosis from the bleeding risk inadvertently associated with current therapy inspired the development of agents directed towards this step in the coagulation process.

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Fractional flow reserve for guiding coronary intervention and functional SYNTAX score

All About Cardiovascular System and Disorders

But it need not imply the actual functional significance of the stenosis in terms of flow physiology. identified physiologically significant stenosis. Using a side branch stent increases the risk of stent thrombosis in the main vessel and is especially to be avoided in a thrombotic situation as in acute myocardial infarction.

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A man in his 30s with cardiac arrest and STE on the post-ROSC ECG

Dr. Smith's ECG Blog

As in all ischemia interpretations with OMI findings, the findings can be due to type 1 AMI (example: acute coronary plaque rupture and thrombosis) or type 2 AMI (with or without fixed CAD, with severe regional supply/demand mismatch essentially equaling zero blood flow).

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Engineering extracellular vesicles for targeted therapeutics in cardiovascular disease

Frontiers in Cardiovascular Medicine

These vesicles carry complex cargo, including proteins, lipids, and nucleic acids, that reflects the physiological or pathological state of their cells of origin. For example, proteins involved in inflammation, thrombosis, and cardiac remodeling have been identified as potential therapeutic targets.

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Patient is informed of her husband's death: is it OMI or it stress cardiomyopathy?

Dr. Smith's ECG Blog

Angiography was technically challenging as the patient was receiving CPR, but the cardiologist suspected acute stent thrombosis and initiated cangrelor, although no repeat angiography was able to be obtained. With regard to the Physiologic Chain Reaction As per Dr. Frick We do not have all the answers.