Physiologically Speaking

JULY 24, 2024

We talk about why the ketogenic diet is helpful for people with diabetes and then dive into the details of each study to explore how 10 years on the diet affected cardiovascular health risk factors and clinical biomarkers. Andrew posted two great threads about the papers on X. You can check those out below.

Diabetes 115

Diabetes Diet Physiology Biomarkers 115

Medical Xpress - Cardiology

SEPTEMBER 25, 2024

Obstructive sleep apnea may be a risk factor for developing abdominal aortic aneurysms, according to researchers from the University of Missouri School of Medicine and NextGen Precision Health.

Aneurysm 74

Aneurysm Aortic Physiology Risk Factors 74

Physiologically Speaking

JULY 26, 2024

Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. Sleep duration has traditionally received most of the attention as a modifiable risk factor. This irregular sleep pattern misaligns circadian rhythms and disrupts physiology. on Tuesday, and 7 on Wednesday.

Chronic Disease 64

Chronic Disease Physiology Atrial Flutter Atrial Fibrillation 64

Circulation

DECEMBER 7, 2023

Resistance training not only can improve or maintain muscle mass and strength, but also has favorable physiological and clinical effects on cardiovascular disease and risk factors. Circulation, Ahead of Print.

Cardiovascular Disease 85

Cardiovascular Disease Exercise Risk Factors Physiology 85

Journal of the American Heart Association

JANUARY 9, 2024

The unique underlying anatomic and physiological background further adds to the difficulty in eliminating the AF burden in these patients. Herein, we provide an overview of the current knowledge on the pathophysiology and risk factors for AF in adult congenital heart disease, with a special focus on the existing challenges in AF ablation.

Congenital Heart Disease 75

Congenital Heart Disease Atrial Fibrillation Congenital Heart Disease 75

Physiologically Speaking

DECEMBER 22, 2023

Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. Not only does exercise help to maintain a healthy weight and/or promote weight loss, but it can also keep cardiometabolic risk factors in check in the absence of weight loss. The Journal of Physiology.

Exercise 52

Exercise Physiology Blood Pressure Cholesterol 52

Physiologically Speaking

DECEMBER 22, 2023

Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. Not only does exercise help to maintain a healthy weight and/or promote weight loss, but it can also keep cardiometabolic risk factors in check in the absence of weight loss. The Journal of Physiology.

Exercise 52

Exercise Physiology Blood Pressure Cholesterol 52

Physiologically Speaking

JUNE 7, 2024

Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. The optimal amount of time for each designated activity differed depending on the cardiometabolic risk factor being considered. To receive new posts and support my work, consider becoming a free or paid subscriber.

Physiology 52

Physiology Exercise Blood Pressure Outcomes 52

Physiologically Speaking

MARCH 8, 2024

Welcome to the Physiology Friday newsletter. On Wednesday, I published a post on the philosophy and physiology of an “exercise pill.” Physiologically Speaking is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber. Acute sleep loss is also insidious.

Physiology 52

Physiology Exercise Diet Research 52

Open Heart

MAY 27, 2024

Background Pre-existing cardiovascular disease (CVD) or cardiovascular risk factors have been associated with an increased risk of complications following hospitalisation with COVID-19, but their impact on the rate of recovery following discharge is not known. to 0.89) and cardiovascular risk factors (aOR 0.66, 95% CI 0.50

COVID-19 52

COVID-19 Cardiovascular Disease Risk Factors Physiology 52

Frontiers in Cardiovascular Medicine

JUNE 26, 2024

Hypertension is a significant risk factor for cardiovascular and cerebrovascular diseases and has become a global public health concern. Although hypertension results from a combination of factors, the specific mechanism is still unclear. We provide a summary of the composition and physiological role of gut microbiota.

Hypertension 52

Hypertension Cerebrovascular Disease Public Health Transplant 52

Physiologically Speaking

JANUARY 26, 2024

Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. What if your calendar was the key to living a longer, healthier life? Health and time have always been two sides of the same coin, but we haven’t had the technology to bridge them until now.

Physiology 52

Physiology Diet Cardiovascular Disease BMI 52

Frontiers in Cardiovascular Medicine

JANUARY 25, 2024

It is frequently driven by physiologic factors such as hypotension, tachycardia, and anemia. Compared to nonoperative myocardial infarction, perioperative myocardial infarction carries an increased risk of adverse outcomes including all-cause mortality.

Myocardial Infarction 64

Myocardial Infarction Physiology Tachycardia Risk Factors 64

MIBHS

JANUARY 31, 2025

The Role of Wearable Technology in Heart Health Wearable tech is designed to monitor physiological data and provide actionable insights to users. Wearables that track sleep patterns can identify disruptions, such as sleep apnea, which is a known risk factor for heart disease.

Heart Rhythm 52

Heart Rhythm Technology AFIB Exercise 52

Journal of Cardiovascular Pharmacology

OCTOBER 21, 2024

Cardiac hypertrophy is a crucial risk factor for heart failure when the heart is confronted with physiological or pathological stimuli. Cardiac hypertrophy is a crucial risk factor for heart failure when the heart is confronted with physiological or pathological stimuli.

Physiology 40

Physiology Heart Failure Risk Factors Article 40

Hypertension Journal

SEPTEMBER 28, 2023

This may be partly due to the disproportionate incidence of salt sensitivity of blood pressure in Black people, a cardiovascular risk factor that is independent of blood pressure and has no proven therapy.

Blood Pressure 40

Blood Pressure Physiology Hypertension Risk Factors 40

MIBHS

NOVEMBER 30, 2023

The exact mechanisms behind this link are complex, but it’s believed that the combination of lifestyle factors associated with depression (such as poor diet, lack of exercise, and smoking) and the physiological effects of depression on the body (including inflammation and blood clotting) can contribute to heart problems.

Blood Pressure 52

Blood Pressure Heart Disease Blood Clot Physiology 52

Hypertension Journal

NOVEMBER 9, 2023

To further investigate the mechanisms of primary hypertension, it is imperative to consider novel potential aspects, such as fluid management by the skin, in addition to the conventional risk factors.

Hypertension 40

Hypertension Blood Pressure Physiology Risk Factors 40

Wellnest

JANUARY 23, 2024

Chirag Doshi, the director of the UN Mehta Institute of Cardiology and Research Centre (UNMICRC), has highlighted the increasing global incidence of cardiovascular diseases, attributing it to lifestyle choices and various risk factors. Chronic stress triggers physiological responses that can adversely affect the cardiovascular system.

COVID-19 52

COVID-19 Cardiovascular Disease Risk Factors Blood Pressure 52

Stroke: Vascular and Interventional Neurology

JUNE 20, 2024

While traditional vascular risk factors (eg, hypertension, dyslipidemia, tobacco use) account for 20% of the explained variance in carotid atherosclerosis, they remain a prominent focus for primary and secondary ischemic stroke prevention strategies. Stroke: Vascular and Interventional Neurology, Ahead of Print.

Cerebrovascular Disease 40

Cerebrovascular Disease Atherosclerosis Atrial Fibrillation Physiology 40

Open Heart

MARCH 21, 2022

Sensitivity analysis was done by cardiac risk factors, degree of stenosis and image quality. Future research is required to evaluate the physiological relevance and prognostic value of FFR CT. Results A total of 535 coronary segments in 60 patients were assessed.

Plaque 40

Plaque Physiology Stenosis Risk Factors 40

Stroke: Vascular and Interventional Neurology

MARCH 6, 2024

CONCLUSIONHypertension is prevalent among adult and pediatric patients with MMD with contributions from known vascular risk factors. Posterior circulation involvement was a negative predictor for response of hypertensive status to revascularization (OR, 0.10 [95% CI, 0.01–0.79]).CONCLUSIONHypertension

Hypertension 40

Hypertension Blood Pressure Pediatrics Kidney Disease 40

Stroke Journal

JANUARY 30, 2025

Ischemic stroke, a heterogeneous disease with various etiological subtypes and risk factors, places stress on the BBB. Microvessels were matured for two days under physiological flow (~5 dyne cm-2). To model stenosis, a microactuator was mounted on a 3D printed platform and connected to a capillary tube (~1 mm diameter).

Stenosis 40

Stenosis Physiology Risk Factors Stroke 40

Dr. Smith's ECG Blog

APRIL 20, 2018

Given her risk factors (HTN, HLD, ESRD from diabetes) I decided to obtain a broad cardiac workup for the patient: serial ECGs, labs, serial troponins, CXR and bedside cardiac ultrasound. First, the patient is such a young woman to have an occlusion MI (OMI), the likely difference being her significant risk factors.

Chest Pain 40

Chest Pain Ultrasound Risk Factors STEMI 40

Physiologically Speaking

SEPTEMBER 20, 2024

Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. Rather than use the traditional view of exercise improving risk factors for disease, they posit an evolutionary explanation underlying why physical activity stimulates health-promoting, adaptive processes.

Exercise 114

Exercise Physiology Blood Pressure Obesity 114

Physiologically Speaking

MARCH 22, 2024

Welcome to the Physiology Friday newsletter. On Wednesday, I published a post about the recent media frenzy on a study showing a 91% increase in the risk of cardiovascular death in people who practice time-restricted eating. Physiologically Speaking is a reader-supported publication. Just one of the many reasons to avoid it.

Physiology 98

Physiology Blood Pressure Exercise Cardiovascular Disease 98

Dr. Sanjay Gupta

DECEMBER 19, 2022

Genetics and physiological stress are also risk factors. The big problem is that as nothing major is found, there is nothing to fix and this leaves the poor patient feeling very perplexed and uncertain about their future.

Heart Attack 40

Heart Attack Heart attacks Blood Clot Chest Pain 40

Physiologically Speaking

DECEMBER 15, 2023

Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. The benefit of resistance training observed in observational studies is supported by controlled trials on resistance training, which demonstrate that this type of exercise reduces traditional and nontraditional CVD risk factors.

Physiology 52

Physiology Exercise Blood Pressure Risk Factors 52

Physiologically Speaking

DECEMBER 15, 2023

Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. The benefit of resistance training observed in observational studies is supported by controlled trials on resistance training, which demonstrate that this type of exercise reduces traditional and nontraditional CVD risk factors.

Physiology 52

Physiology Exercise Blood Pressure Risk Factors 52

Dr. Smith's ECG Blog

DECEMBER 18, 2022

He has no cardiovascular risk factors except smoking for 10 pack-years. In addition — Morphology of the QRS complex and ST-T wave of lead V3 does not make physiologic sense in ECG #1 , considering the relative size and shape of the QRST complex in neighboring leads V2 and V4. His medical exam is unremarkable. What do you think

Myocardial Infarction 40

Myocardial Infarction Chest Pain Blog Echocardiogram 40

Physiologically Speaking

MARCH 29, 2024

Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. Physiological processes like the release of hormones and neurotransmitters, blood pressure, and insulin sensitivity oscillate throughout the day. A new study published in the Journal of Physiology sought to find out.

Blood Pressure 52

Blood Pressure Exercise Physiology Hypertension 52

Heart BMJ

FEBRUARY 26, 2025

However, current guidelines adopt a more liberal stance, and evidence on risk factors for exercise-related sudden cardiac death remains limited. This study investigated the clinical, morphological and genetic factors associated with high-intensity physical activity-related sudden cardiac death in hypertrophic cardiomyopathy.

Sudden Cardiac Death 59

Sudden Cardiac Death Cardiomyopathy Exercise Risk Factors 59

Open Heart

SEPTEMBER 13, 2024

Background Pregnant patients with single ventricle (SV) physiology carry a high risk of spontaneous pregnancy loss (SPL), yet the clinical factors contributing to this risk are not well defined. Identifying these clinical risk factors can guide preconception counselling by the cardio-obstetrics team.

Physiology 52

Physiology Risk Factors Arrhythmia Outcomes 52

Open Heart

DECEMBER 23, 2024

Background Hypertension is a risk factor for bleeding events and is included in the HAS-BLED (Hypertension, Abnormal renal/liver function, Stroke, Bleeding history or predisposition, Labile INR, Elderly, Drugs/Alcohol concomitantly) score.

Blood Pressure 40

Blood Pressure Peripheral Arterial Disease Kidney Disease Laboratory 40

Cardiometabolic Health Congress

FEBRUARY 1, 2024

Other studies have also unearthed more intricate connections which suggests that physiological conditions, underpinned by biological and chemical factors, may also play a pivotal role in influencing cardiovascular disease (CVD). The strongest evidence in this area pertains to symptoms of depression and anxiety.” JAMA Netw Open.

Cardiovascular Disease 105

Cardiovascular Disease Coronary Artery Bypass Graft Heart Disease Risk Factors 105

DAIC

JULY 18, 2024

Characterizing anatomical and physiological parameters through the amount and type of plaque in a patient’s artery is essential to understanding their risk of heart attack and stroke.

Plaque 105

Plaque Heart Attack Heart attacks Cardiovascular Disease 105

Physiologically Speaking

MARCH 6, 2024

For one, drugs target single pathways or risk factors. Exercise perturbs our entire physiology, and it’s this disruption of homeostasis, integrative crosstalk, and subsequent adaptations that lead to the immense health benefits achieved through physical activity. Statins lower cholesterol.

Exercise 92

Exercise Blood Pressure Risk Factors Physiology 92