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Active plant substance found to reduce pulmonary hypertension

Medical Xpress - Cardiology

Pulmonary hypertension is a very serious disease that leads to heart failure and death in many patients.

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Bidirectional glenn surgery without palliative pulmonary artery banding in univentricular heart with unrestricted pulmonary flow. Retrospective multicenter experience

Journal of Cardiothoracic Surgery

Although pulmonary artery banding (PAB) has been generally acknowledged as an initial palliative treatment for patients having single ventricle (SV) physiology and unrestrictive pulmonary blood flow (UPBF), it.

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Is the Heart Really a Pump? New Perspectives on Cardiovascular Physiology

Physiologically Speaking

Cardiovascular physiology has long held that the heart is a mechanical pump and that the heart’s propulsive power is the main driver of blood flow throughout the body. While he didn't fully grasp the complete circulatory system, his insights into the pulmonary circulation were notable for the time.

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Mechanosensitive channels TMEM63A and TMEM63B mediate lung inflation–induced surfactant secretion

Journal of Clinical Investigation - Cardiology

Pulmonary surfactant is a lipoprotein complex lining the alveolar surface to decrease the surface tension and facilitate inspiration. TMEM63A/B were predominantly localized at the limiting membrane of the lamellar body (LB), a lysosome-related organelle that stores pulmonary surfactant and ATP in AT2 cells.

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Physiology Friday #205: What Limits VO2 Max? It Might Depend on Your Fitness Level.

Physiologically Speaking

Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. There’s a long-running debate in exercise physiology about what limits VO2 max. Physiology is integrative, not isolated. To receive new posts and support my work, consider becoming a free or paid subscriber.

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Clinical risk associated with COVID-19 among 86000 patients with congenital heart disease

Open Heart

The excess risk of COVID-19 hospitalisation and death rose with increasing physiological severity of CHD (presence of pulmonary vascular disease and/or cyanosis), rather than anatomical complexity. Of patients with a positive COVID-19 test, patients with CHD were more likely than controls to be hospitalised (22.4%

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Artificial intelligence to improve the diagnosis of pulmonary hypertension: promises and pitfalls

Heart BMJ

Challenges in the diagnosis of pulmonary hypertension Pulmonary hypertension (PH) is a clinical–physiological syndrome thought to affect 1% of the global population. 1 PH is defined haemodynamically by mean pulmonary artery pressure >20 mm Hg, resulting in right ventricular (RV) overload and often RV failure.