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Ischemia with no obstructed coronary arteries and microvascular testing procedures: a review of utility, pharmacotherapy, and current challenges

Frontiers in Cardiovascular Medicine

This review addresses the pathophysiology, diagnostic approaches, and management strategies associated with INOCA, emphasizing epicardial coronary spasms and coronary microvascular dysfunction (CMD) as underlying mechanisms and myocardial bridging (MB) as a risk factor.

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Screening & treating maternal psychological health key to improving cardiovascular health

American Heart News - Heart News

Statement Highlights: It is essential for health care professionals to routinely screen pregnant and postpartum women for depression and anxiety, address modifiable risk factors and consider behavioral and pharmacological interventions to improve.

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Current Mouse Models of Intracranial Aneurysms: Analysis of Pharmacological Agents Used to Induce Aneurysms and Their Impact on Translational Research

Journal of the American Heart Association

Hence, to date, no single pharmacological option exists to treat them. Genetic modification in a mouse model of IAs, including deletion or overexpression of a particular gene, provides an excellent means for examining basic mechanisms behind disease pathophysiology and developing novel pharmacological approaches.

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A smartphone-guided secondary prevention digital health application reduces systolic blood pressure in patients with chronic coronary syndrome and insufficient blood pressure control

Frontiers in Cardiovascular Medicine

Several modifiable risk factors, including increased blood pressure (BP), significantly contribute to cardiovascular risk in CCS. Therefore, optimal secondary prevention includes managing BP through lifestyle changes and pharmacological therapy.

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Cannabis use disorder: from neurobiology to treatment

Journal of Clinical Investigation - Cardiology

We will first describe the epidemiology and burden of disease of CUD, including risk factors associated with CUD (both in terms of general risk and genetic risk variants). Although no pharmacological interventions are yet approved for CUD, we present the most promising pharmacological interventions being tested.

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Lipoprotein(a) as a Pharmacological Target: Premises, Promises, and Prospects

Circulation

Lp(a) (lipoprotein [a]) has recently garnered attention as an independent risk factor for astherosclerotic cardiovascular disease, with proinflammatory and prothrombotic mechanisms contributing to its atherogenicity. Atherosclerotic cardiovascular disease is a major health concern worldwide and requires effective preventive measures.

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Polypill: a harmonious blend of stoicism and pragmatism in primary cardiovascular prevention

Heart BMJ

Despite the existence of well-established risk factors and effective pharmacological treatments for major cardiovascular disease (CVD), these conditions remain among the leading causes of premature death and disability, exerting a substantial burden on health systems worldwide.