article thumbnail

Novel pharmacological approaches to lowering blood pressure and managing hypertension

Nature Reviews - Cardiology

In this Review, Dhaun and colleagues discuss the reasons for poor control of hypertension, such as therapeutic inertia and poor patient adherence, as well as novel pharmacological approaches to blood pressure lowering.

article thumbnail

Contemporary pharmacological treatment and management of heart failure

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 26 March 2024; doi:10.1038/s41569-024-00997-0 In this Review, Bozkurt provides an overview of the management of patients with heart failure across the full range of left ventricular ejection fraction, derived from the recommendations in the latest US and European guidelines.

article thumbnail

Piperine Shows Potential Pharmacological Benefit for NAFLD, Early Cirrhosis

HCPLive

Consuming a 5mg piperine capsule once daily for 12 weeks was linked to several pharmacological improvements in patients with NAFLD.

article thumbnail

Current Mouse Models of Intracranial Aneurysms: Analysis of Pharmacological Agents Used to Induce Aneurysms and Their Impact on Translational Research

Journal of the American Heart Association

Hence, to date, no single pharmacological option exists to treat them. Genetic modification in a mouse model of IAs, including deletion or overexpression of a particular gene, provides an excellent means for examining basic mechanisms behind disease pathophysiology and developing novel pharmacological approaches.

article thumbnail

The Pharmacological Aspects of Adalimumab Biosimilars

HCPLive

A clinical pharmacist reviews the various pharmacological aspects of the available adalimumab biosimilars.

article thumbnail

Nonpharmacological interventions on glycated haemoglobin in youth with type 1 diabetes: a Bayesian network meta-analysis

Cardiovascular Diabetology

The available evidence on the impact of specific non-pharmacological interventions on glycaemic control is currently limited. Consequently, there is a need to determine which interventions could provide the mo.

article thumbnail

Lifestyle Changes and Non-Pharmacological Options for Fibromyalgia

HCPLive

A key opinion leaders explore effective non-pharmacological therapies and lifestyle modifications that have shown significant promise in managing fibromyalgia symptoms, complementing traditional medication-based approaches.