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Over-the-counter supplement found to improve walking for peripheral artery disease patients

Medical Xpress - Cardiology

The over-the-counter supplement nicotinamide riboside, a form of vitamin B3, increased the walking endurance of patients with peripheral artery disease, a chronic leg condition for which there are few effective treatments.

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Association of plasma aldosterone concentration with peripheral artery disease in hypertensive patients: insights from a large cross-sectional analysis

Frontiers in Cardiovascular Medicine

ObjectivesTo investigate the relationship between plasma aldosterone concentration (PAC) and the prevalence of peripheral artery disease (PAD) in hypertensive patients and to determine any potential threshold effects.MethodsThis cross-sectional study analyzed data from 13,157 hypertensive individuals from the People's Hospital of Xinjiang Uygur Autonomous (..)

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Intravascular Ultrasound Outperforms Angiography for Peripheral Artery Disease Treatment

DAIC

The study, called IVUS-DCB, is the first randomized controlled trial to demonstrate the clinical benefits of using IVUS in angioplasty procedures for peripheral artery disease (PAD), a condition in which plaque builds up in arteries in the legs.

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Exploring research trends and hotspots on PCSK9 inhibitor studies: a bibliometric and visual analysis spanning 2007 to 2023

Frontiers in Cardiovascular Medicine

BackgroundFollowing the identification of proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors, research in this area has experienced significant growth. However, a thorough bibliometric analysis of this burgeoning field remains conspicuously absent.

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Cancer drug could be used to save the limbs of peripheral artery disease patients, pre-clinical study suggests

Medical Xpress - Cardiology

Researchers at the Heart Research Institute (HRI) have made a new discovery, finding an existing drug used to kill tumor cells in cancer patients could also be used to save the limbs of patients with blocked arteries in their legs.

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2025 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association

Circulation

METHODS:The AHA, through its Epidemiology and Prevention Statistics Committee, continuously monitors and evaluates sources of data on heart disease and stroke in the United States and globally to provide the most current information available in the annual Statistical Update with review of published literature through the year before writing.

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Nonlinear association between red cell distribution width/albumin ratio and peripheral arterial disease in the NHANES: a cross-section study with propensity score matching analysis

Frontiers in Cardiovascular Medicine

Further prospective clinical research is required to validate the relationship between the RDW/ALB ratio and PAD. Subgroup and PSM analyses underscored the consistency of these findings.ConclusionsThe study demonstrated a significant association between RDW/ALB and PAD, with a nonlinear relationship and a threshold effect.