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Semaglutide and Walking Capacity in People With Symptomatic Peripheral Artery Disease and Type 2 Diabetes

American College of Cardiology

The goal of the phase 3b STRIDE trial was to evaluate the safety of once-weekly injections of the GLP-1 receptor agonist semaglutide and to determine whether it improves function (symptoms and quality of life [QoL]) in patients with symptomatic peripheral artery disease (PAD) and type 2 diabetes (T2D) with functional limitations.

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New Guidelines on Peripheral Artery Disease Issued by American Heart Association, American College of Cardiology and Leading Medical Societies

DAIC

A new joint guideline from the American Heart Association (AHA), the American College of Cardiology (ACC) and nine other medical societies reports early diagnosis and treatment of peripheral artery disease is essential to improve outcomes and reduce amputation risk, heart attack, stroke and death for people with Peripheral Artery Disease (PAD).

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Peripheral Artery Disease: Implications For Health and Quality of Life

American College of Cardiology

Peripheral artery disease (PAD) represents a significant global health burden, affecting >200 million people and accounting for approximately 10-15% of the population >50 years of age.

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Revascularization enhances quality of life for patients with chronic limb threatening ischemia

Science Daily - Heart Disease

Over 200 million people around the world experience peripheral artery disease (PAD) -- a condition caused by the narrowing of the blood vessels from the heart to the lower limbs that leads to pain when walking -- and for roughly 1-in-10 this advances to chronic limb-threatening ischemia (CLTI), an advanced form of PAD.

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How to Prevent Peripheral Artery Disease

AMS Cardiology

However, when these arteries become narrowed or blocked conditions like Peripheral Artery Disease (PAD) can emerge, posing a threat to our overall health. Understanding Peripheral Artery Disease Peripheral artery disease or PAD is a condition in which plaque builds up in the arteries that lead to the legs and feet.

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Revascularization may enhance quality of life for patients with chronic limb threatening ischemia

Medical Xpress - Cardiology

A new study reveals diminished quality of life among patients with chronic limb-threatening ischemia, a severe form of peripheral artery disease, and emphasizes the benefits of revascularization on well-being.

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STRIDE and SOUL: Semaglutide Improves PAD Outcomes; Oral Formulation Effective

American College of Cardiology

Semaglutide, compared to placebo, significantly improved walking distance, symptoms and quality of life in participants with symptomatic peripheral artery disease (PAD) and type 2 diabetes (T2D), according to results of the STRIDE study presented at ACC.25