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They included randomised controlled trials that enrolled adults undergoing major cardiac surgeries and reported postpericardiotomy syndrome, pericardial effusion and pericarditis as primary or secondary outcomes. to 0.81) and may prevent postoperative pericarditis (RR 0.66, 95% CI 0.45 Pairs of reviewers screened eligible studies.
Acute pericarditis is characterized by pericardial inflammation which can be treated with anti-inflammatory drugs. A considerable percentage of patients develops recurrent pericarditis with several relapses. Two pathophysiological mechanisms have been described for idiopathic recurrent pericarditis, autoimmune and autoinflammatory.
Recurrent pericarditis (RP) is the most troublesome complication of acute pericarditis reflecting an unresolving inflammation of the pericardial sac around the heart and associated with significant morbidity.
Traditionally used as an anti-inflammatory for pericarditis (inflammation of the lining of the heart), it has recently been shown to result in fewer major heart events in those with a recent heart attack. It is an easy win, frequently missed. Low-dose colchicine of 0.5mg daily resulted in a 23% reduction in future heart events 11.
This may result from fluctuations in heart rate or in nervous system activity or from pharmacologic treatment. Conduction and Refractoriness Alternans — entails variance of impulse propagation along some par t of the conduction system. This conclusion may prove useful in contemplating potential investigative and therapeutic interventions.
The second most common cause of medical cardiac tamponade is acute idiopathic pericarditis. Less common etiologies include uremia, bacterial or tubercular pericarditis, chronic idiopathic pericarditis, hemorrhage, and other causes such as autoimmune diseases, radiation, myxedema, etc.
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