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A study of genetics of pericarditis increases understanding of newly approved drug treatment

Medical Xpress - Cardiology

Sequence variants that protect against pericarditis have been discovered at a genomic locus encoding interleukin-1 immune cytokines. A newly approved drug treatment for pericarditis inhibits these cytokines, according to a new study.

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Pericarditis for the ages: differential outcomes and therefore age-specific therapies?

Heart BMJ

Acute pericarditis (AP) is the second most common cardiac cause of chest pain, diagnosed when at least two of the following criteria are met: characteristic pleuritic chest pain, pericardial rub on auscultation, new typical ECG changes (such as widespread ST-elevation or PR-depression) and pericardial effusion on imaging.

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ECG Blog #365 — A 30yo with Pericarditis.

Ken Grauer, MD

The patient was discharged with a diagnosis of acute pericarditis — and treated with a full course of colchicine and ibuprofen. The ultimate discharge diagnosis was acute pericarditis. ( From the information provided — I would not make the diagnosis of acute pericarditis. Figure-1: The initial ECG in today's case.

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Efficacy of colchicine in addition to anakinra in patients with recurrent pericarditis

Open Heart

Aim Anakinra, an anti IL-1 agent targeting IL-1 alfa and beta, is available for the treatment of recurrent pericarditis in cases with corticosteroid dependence and colchicine resistance after failure of conventional therapies. The efficacy endpoint was recurrence rate and the time to the first recurrence. females, 80.9%

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Subacute hemorrhagic pericardial tamponade after COVID-19 infection mimicking carcinomatous pericarditis: a case report

Frontiers in Cardiovascular Medicine

Background Coronavirus disease (COVID-19)-associated acute pericarditis has recently received much attention owing to its high frequency associated with pericardial tamponade (PT), showing unfavorable prognosis. Conclusions We encountered a unique case of COVID-19-associated acute pericarditis exhibiting hemorrhagic PT.

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Causal relationship between COVID-19 and myocarditis or pericarditis risk: a bidirectional Mendelian randomization study

Frontiers in Cardiovascular Medicine

Background & aims Coronavirus disease 2019 (COVID-19) is strongly associated with myocarditis or pericarditis risk in observational studies, however, there are still studies that do not support the above conclusion. Results Non-associations in the IVW and sensitivity analyses were observed for COVID-19 with myocarditis or pericarditis.

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What does this ECG show?

Dr. Smith's ECG Blog

Overall, this looks like one of the rare ECGs that is actually specific for pericarditis in my opinion. Pericarditis maybe." Meyers' words — "is one of the rare ECGs that is actually specific for pericarditis". ii ) Today's case emphasizes the importance of the history in making the diagnosis of pericarditis.