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A study of genetics of pericarditis increases understanding of newly approved drug treatment

Medical Xpress - Cardiology

Sequence variants that protect against pericarditis have been discovered at a genomic locus encoding interleukin-1 immune cytokines. A newly approved drug treatment for pericarditis inhibits these cytokines, according to a new study.

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Fate of coronary arteries in Constrictive pericarditis

Dr. S. Venkatesan MD

Inflammatory pericarditis can occur in differential fashion. For example, the most common chronic pericarditis tuberculosis affects the fibrinous layer. Post MI pericarditis involves the epicardium. Diastolic Coronary Artery Compression in Constrictive Pericarditis. Angina caused by calcific constrictive pericarditis.

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Pericarditis for the ages: differential outcomes and therefore age-specific therapies?

Heart BMJ

Acute pericarditis (AP) is the second most common cardiac cause of chest pain, diagnosed when at least two of the following criteria are met: characteristic pleuritic chest pain, pericardial rub on auscultation, new typical ECG changes (such as widespread ST-elevation or PR-depression) and pericardial effusion on imaging.

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Age-stratified patterns in clinical presentation, treatment and outcomes in acute pericarditis: a retrospective cohort study

Heart BMJ

Background There are limited data on acute pericarditis according to different age groups. The aim of this study is to investigate the role of age-related features in clinical characteristics, management, and outcomes of acute pericarditis, with a focus on the geriatric population. and G4: 16.2%; p<0.001). to 5.58, p<0.001).

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ECG Blog #365 — A 30yo with Pericarditis.

Ken Grauer, MD

The patient was discharged with a diagnosis of acute pericarditis — and treated with a full course of colchicine and ibuprofen. The ultimate discharge diagnosis was acute pericarditis. ( From the information provided — I would not make the diagnosis of acute pericarditis. Figure-1: The initial ECG in today's case.

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Efficacy of colchicine in addition to anakinra in patients with recurrent pericarditis

Open Heart

Aim Anakinra, an anti IL-1 agent targeting IL-1 alfa and beta, is available for the treatment of recurrent pericarditis in cases with corticosteroid dependence and colchicine resistance after failure of conventional therapies. The efficacy endpoint was recurrence rate and the time to the first recurrence. females, 80.9%

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Causal relationship between COVID-19 and myocarditis or pericarditis risk: a bidirectional Mendelian randomization study

Frontiers in Cardiovascular Medicine

Background & aims Coronavirus disease 2019 (COVID-19) is strongly associated with myocarditis or pericarditis risk in observational studies, however, there are still studies that do not support the above conclusion. Results Non-associations in the IVW and sensitivity analyses were observed for COVID-19 with myocarditis or pericarditis.