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Suddencardiacdeath represents a significant mortality factor in hypertrophic cardiomyopathy (HCM). Nevertheless, the validation of the existing risk prediction model in the pediatric population remains insufficiently explored.
All patients underwent cardiac catheterization, with 45 (80%) undergoing at least 1 interventional procedure. Causes of death included multiorgan failure (35%), progressive respiratory failure (20%), and suddencardiacdeath (15%). 95% CI, 2.214.1];P<0.001). P<0.001).
What is the association between late gadolinium enhancement (LGE) on cardiac magnetic resonance imaging (cMRI) and suddencardiacdeath (SCD) in pediatric patients with hypertrophic cardiomyopathy (HCM), and does it add to pediatric SCD risk models?
Subcutaneous ICDs (S-ICD) are a treatment option for the prevention of suddencardiacdeath in pediatric patients. However, in a 2020 multicenter study of pediatric patients with a S-ICD found a risk of inappropriate shock (IS) double that of a large adult study. The S-ICD has limited programming options.
Inherited arrhythmias (IAs) account for a significant proportion of suddencardiacdeath (SCD) in young patients without overt heart disease. To date, the studies of Asian pediatric population with IAs are rarely reported.
The Brugada Syndrome (BrS) is a rare inherited disorder predisposing patients to arrythmia and suddencardiacdeath. In 2014 a first comprehensive review of diagnostic and therapeutic strategies in the pediatric BrS was published 3. A considerable number of patients are already symptomatic in infancy 2.
There has been a recent surge of interest in efforts to refine the risk stratification for suddencardiacdeath (SCD) in children and adolescents with hypertrophic cardiomyopathy (HCM).
The guideline, according to a written statement shared here, reiterates the importance of collaborative decision-making with patients who have HCM and provides updated recommendations for the most effective treatment pathways for adult and pediatric patients. Several recommendations in the new guideline extend to pediatric patients.
Brugada syndrome is thought to account for about one fourth of suddencardiacdeaths in individuals with structurally normal heart. It is seldom done in pediatric age group. Yet, SCN5A variants are identified in only about one fifth of persons with Brugada syndrome. With proper precautions, risk can be reduced.
This discussion comes from this previous post: Hyperthermia and ST Elevation Discussion Brugada Type 1 ECG changes are associated with suddencardiacdeath (SCD) and the occurrence of ventricular dysrhythmias. Pediatric and elderly patients were more predisposed to developing an arrhythmic event in the setting of fever [7].
The granulomatous inflammation affects the heart, causing an infiltrative cardiomyopathy The most common manifestations of cardiac sarcoidosis are atrioventricular (AV) block and ventricular tachyarrhythmias (VT). SCD (suddencardiacdeath) from sarcoid heart disease is thought to be caused by either from high-grade AV block or VT.
The limb lead abnormalities appear to be part of the Brugada pattern, as described in this article: Inferior and Lateral Electrocardiographic RepolarizationAbnormalities in Brugada Syndrome Discussion Brugada Type 1 ECG changes are associated with suddencardiacdeath (SCD) and the occurrence of ventricular dysrhythmias.
IntroductionThe diagnostic performance of automated analysis of electrocardiograms for screening children with pediatric heart diseases at risk of suddencardiacdeath is unknown.
We are not using any human or patient data; we are only comparing the rule-of-thumb to various formulas, which may or may not be correspondingly validated by health data (the risk of suddencardiacdeath, for instance). Here we can compare the different formulas, using a cutoff of 480 ms to determine when the QTc is prolonged.
BACKGROUND:Sudden cardiacdeath is the most common cause of death in childhood hypertrophic cardiomyopathy (HCM). Recently, 2 risk scores have been developed to estimate the 5-year risk of suddencardiacdeath.
Fever not only unmasks a Brugada-type electrocardiogram (ECG) but also increases the risk of ventricular tachyarrhythmias such as ventricular fibrillation (VF) or suddencardiacdeath. Twenty-one percent (18 of 88) had a family history of suddencardiacdeath and 26.4% (14 of 53) carried a pathogenic SCN5A mutation.
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