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Allogenic HSCT May Improve Sickle Cell Disease-Related Organ Dysfunction

HCPLive

A new analysis summarized evidence on the effects of allogeneic HSCT on SCD-related organ dysfunction in pediatric and adult patients with SCD.

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Clinical Pain Screening Proves Feasible in Pediatric Sickle Cell Disease

HCPLive

Over the study period, pain screening procedures were integrated within routine clinical visits and providers’ workflow in sickle cell disease care.

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Lantheus Announces the FDA Approval of DEFINITY as Ultrasound Enhancing Agent for Use in Certain Pediatric Cardiovascular Patients

DAIC

Food and Drug Adminstration (FDA) has approved DEFINITY (Perflutren Lipid Microsphere) as an ultrasound enhancing agent for use in pediatric patients with suboptimal echocardiograms, including those who have undergone heart transplant, or have Kawasaki disease or a congenital cardiovascular anomaly. Lantheus announced that the U.S.

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Voxelotor Improves Cerebral Hemodynamic Parameters in Pediatric Sickle Cell Disease

HCPLive

Voxelotor decreases oxygen extraction fraction and cerebral blood flow towards levels observed in healthy children.

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Voxelotor Benefits Red Blood Cell Functionality in Pediatric Sickle Cell Disease

HCPLive

An ancillary study of the phase 2 HOPE-KIDS 1 trial revealed voxelotor is associated with reduced sickling and hemolysis in children with SCD.

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Hematopoietic Stem Cell Transplantation Improves Pediatric SCD Outcomes

HCPLive

A systematic review and meta-analysis of HSCT in children with sickle cell disease demonstrated pooled survival rates exceeding 90%.

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Abstract WP222: Basilar Artery Stenosis in Children With Moyamoya

Stroke Journal

A pediatric neurologist reviewed all records and neuroimaging to verify diagnosis of basilar artery stenosis.Results:Out of our cohort of 331 children with moyamoya, 24 (7.2%) children had basilar artery stenosis. Children with moyamoya and basilar stenosis mentioned in their chart were initially included.