HCPLive

JANUARY 12, 2024

Liver transplantation after prolonged preservation with dual hypothermic oxygenated machine perfusion yielded similar outcomes to standard perfusion, showing no compromised donor liver quality and equal safety for recipients.

Transplant 99

Transplant Outcomes 99

DAIC

FEBRUARY 13, 2024

THE TEXAS HEART INSTITUTE 2024 milla1cf Tue, 02/13/2024 - 17:56 February 13, 2024 — Pediatric heart transplantation has long been hailed as a life-saving intervention for children suffering from end-stage heart failure. This helps us gain a comprehensive understanding of the immune response dynamics within transplanted hearts."

Transplant 111

Transplant Pediatrics Heart Transplant Research 111

HCPLive

NOVEMBER 9, 2024

New data from the UNOS database presented at NASPGHAN 2024 details characteristics and outcomes of pediatric liver transplant patients receiving machine perfused organs.

Transplant 92

Transplant Pediatrics Outcomes 92

DAIC

MAY 31, 2024

By the end of the study cardiologists performed 10% fewer biopsies in the first year post-transplant and 40% fewer in the second year post-transplant despite an increase in follow-up biopsy rates for dual positives. Hanna , CareDx President and CEO.

Heart Transplant 105

Heart Transplant Transplant Outcomes 105

HCPLive

APRIL 15, 2025

Liver transplant recipients with infective endocarditis had greater odds of in-hospital mortality, ICU admission, and longer length of stay.

Transplant 59

Transplant Hospital ICU Outcomes 59

HCPLive

NOVEMBER 5, 2024

Direct-acting antiviral agents have enabled more availability for organ transplant.

Transplant 59

Transplant Outcomes 59

HCPLive

NOVEMBER 17, 2024

Kim explains how poor sleep is linked to negative impacts on mental health, physical health, and frailty after liver transplantation.

Transplant 59

Transplant Outcomes 59

Medical Xpress - Cardiology

FEBRUARY 12, 2024

Pediatric heart transplantation has long been hailed as a life-saving intervention for children suffering from end-stage heart failure. While the procedure offers hope, the long-term outcomes for these young patients remain suboptimal due to allograft rejection and graft failure.

Transplant 71

Transplant Pediatrics Heart Transplant Heart Failure 71

HCPLive

JANUARY 28, 2025

Patients who started dialysis as children but were not waitlisted until young adulthood faced worse outcomes than those who were listed before turning 18.

Transplant 96

Transplant Outcomes 96

Science Daily - Heart Disease

APRIL 26, 2024

Regenerative heart therapies involve transplanting cardiac muscle cells into damaged areas of the heart to recover lost function. The highly positive outcomes observed in primate models highlight the potential of this strategy. However, the risk of arrhythmias following this procedure is reportedly high.

Transplant 131

Transplant Arrhythmia Research Outcomes 131

Journal of Cardiothoracic Surgery

JULY 24, 2024

Lung transplantation (LT) represents a high-risk procedure for end-stage lung diseases. This study describes the outcomes of patients undergoing LT that require massive transfusions as defined by the universal.

Transplant 52

Transplant Outcomes Research 52

DAIC

JANUARY 11, 2024

In organ transplantation, an extended criteria donor is defined as having perceived risk factors linked to poor subsequent outcomes, for example, those with age >55 or ischemic times exceeding 4 hours, which sometimes leads to rejection of the donor organ. utilizing the Paragonix SherpaPak CTS (p=0.022).

Transplant 111

Transplant Heart Transplant Technology Risk Factors 111

HCPLive

AUGUST 23, 2024

The third quarterly issue of 2024 reviews early versus late ERCP outcomes post-transplant, the impact of GLP-1RA use on endoscopic management, and the differential diagnosis of seronegative villous atrophy.

Transplant 105

Transplant Outcomes 105

Conquering CHD

JANUARY 17, 2025

After struggling with heart failure for the first months of his life, doctors told his parents that Zeke would need a heart transplant immediately. Within one day, our heart transplant team performed the transplant surgery. Now Zane, 6, and Zeke, 5, are living lives the odds said were unlikely.

Heart Transplant 98

Heart Transplant Transplant Open-Heart Surgery Nursing 98

Frontiers in Cardiovascular Medicine

JANUARY 23, 2024

Introduction Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in kidney transplant recipient (KTR). There is a dearth of standardized guidelines on optimal cardiovascular evaluation of transplant candidates. Posttransplant MACE has a negative effect on grafts and patient outcomes.

Transplant 64

Transplant Coronary Artery Disease Myocardial Infarction Cardiovascular Disease 64

Cardiovascular Diabetology

FEBRUARY 20, 2025

Cardiovascular disease is a leading cause of post-transplant mortality in kidney transplant recipients (KTRs), especially those with diabetes. Although glucagon-like peptide-1 receptor agonists (GLP-1 RAs) hav.

Transplant 52

Transplant Diabetes Cardiovascular Disease Outcomes 52

HeartRhythm

AUGUST 21, 2024

Among pediatric patients undergoing orthotopic heart transplantation (OHT), 1-12% are reported to need a permanent pacemaker (PPM).1 1 There are limited studies on the outcomes of PPM placement, and the role of implantable cardioverter-defibrillator (ICD) in pediatric OHT remains unclear.

Heart Transplant 40

Heart Transplant Pediatrics Transplant Outcomes 40

Journal of Cardiothoracic Surgery

SEPTEMBER 22, 2024

The outcome of heart transplantation is significantly affected by perioperative infections. Individualised immunosuppression strategies are essential to reduce the risk of such infections.

Heart Transplant 52

Heart Transplant Transplant Outcomes 52

HeartRhythm

MARCH 31, 2025

Up to 10% of patients require permanent pacemaker (PPM) implantation after orthotopic heart transplant (OHT). A range of devices and pacing modalities are available, but limited data exist regarding long-term outcomes of different pacing strategies in post-OHT patients.

Heart Transplant 40

Heart Transplant Transplant Pacemaker Anatomy 40

HeartRhythm

MARCH 31, 2025

Arrhythmias in pediatric heart transplant patients have historically raised concerns for acute rejection, often prompting invasive evaluations and empiric treatment. Despite this, the association of post-transplant arrhythmias with adverse outcomes remains understudied.

Heart Transplant 40

Heart Transplant Transplant Pediatrics Arrhythmia 40

Journal of Cardiothoracic Surgery

FEBRUARY 9, 2024

We examine the factors associated with heart transplant outcomes in this challenging population with complex anatomy requiring redo-sur. Adult patients surviving with congenital heart disease (ACHD) is growing.

Congenital Heart Disease 52

Congenital Heart Disease Heart Transplant Transplant Congenital 52

HeartRhythm

OCTOBER 7, 2024

When intractable, heart transplant (HTX) can become the only viable treatment. Arrhythmias can lead to cardiac arrest (CA) and heart failure. This rare, high-risk cohort has not been reported as a distinct group.

Heart Transplant 40

Heart Transplant Transplant Arrhythmia Cardiac Arrest 40

HeartRhythm

SEPTEMBER 17, 2024

Urgent heart transplantation (HTx) may be considered when all previous strategies fail (1), albeit with substantial post-operative mortality (1). Although HTx is considered as a bail-out strategy, no data exist regarding outcomes of refractory ES patients listed for urgent HTx but ultimately not transplanted during the acute phase.

Transplant 40

Transplant Heart Transplant Ablation Outcomes 40

HCPLive

APRIL 9, 2024

A systematic review and meta-analysis of HSCT in children with sickle cell disease demonstrated pooled survival rates exceeding 90%.

Sickle Cell Disease 59

Sickle Cell Disease Transplant Pediatrics Outcomes 59

Frontiers in Cardiovascular Medicine

MAY 19, 2024

BackgroundThe use of Intra-aortic Balloon Pump (IABP) and Impella devices as a bridge to heart transplantation (HTx) has increased significantly in recent times. Out of them, 12% had primary outcomes indicating Status 2 failure. Our ML models were based on 19 variables from the UNOS data.

Heart Transplant 59

Heart Transplant Transplant BMI Aortic 59

Circulation: Heart Failure

APRIL 4, 2025

Heart transplant (HT) can be a lifesaving therapy for select patients with end-stage heart failure. We review HT practices, rates and post-HT outcomes, underscoring the differences between countries within each region. Circulation: Heart Failure, Ahead of Print. Heart failure is a global disease with significant morbidity.

Heart Transplant 40

Heart Transplant Transplant Heart Failure Article 40

HeartRhythm

MARCH 31, 2025

With the shift to bicaval anastomosis technique for orthotopic heart transplantation (OHT), a decreasing number of patients are requiring permanent pacemaker (PPM) implantation. When bradycardia occurs post-OHT, medications such as terbutaline are used to allow for recovery of the conduction system.

Heart Transplant 40

Heart Transplant Transplant Pacemaker Bradycardia 40

DAIC

FEBRUARY 21, 2024

As the only pediatric heart transplant program in Louisiana and the only program in the state to offer advanced mechanical support options for pediatric cardiology patients, Ochsner Children’s Hospital is committed to advocating for additional medical devices to enhance its high-quality care to pediatric patients awaiting transplant.

Pediatrics 105

Pediatrics Hospital Heart Failure Transplant 105

HCPLive

SEPTEMBER 25, 2024

Leveraging deceased donor kidney transplantation data, study results suggest DCD-V kidney transplantation has similar short- and long-term outcomes versus DCD-III and DBD.

Transplant 64

Transplant Outcomes 64

Stroke Journal

JANUARY 30, 2025

The safety&efficacy of NR1 intracerebral transplantation in chronic stroke patients was assessed over 12 months.Methods:Inclusion Criteria: 18-75 yo; 6-60 mos post-ischemic subcortical MCA stroke; mRS 3-4. Subjects were transplanted with 2.5M, 5M, 10M or 20M. UE FMMS improvement surpassed vagal nerve stimulation outcomes.

Transplant 40

Transplant Stroke Strokes Outcomes 40

DAIC

JUNE 24, 2024

Kittleson, director of Heart Failure Research and director of Post Graduate Medical Education in Heart Failure and Transplantation, is an associate editor specializing in heart failure. She has been a section editor for Circulation: Cardiovascular Outcomes and Research, authored book chapters, and in 2022 was a finalist for the Samuel A.

Heart Failure 100

Heart Failure Transplant Research Interventional Cardiology 100

Circulation

NOVEMBER 11, 2024

Heart transplantation remains a vital treatment for end-stage heart failure, yet the scarcity of suitable donor hearts makes the treatment unavailable to many patients in critical need. Aged donor hearts, despite their availability, exhibit increased primary graft dysfunction and decreased survival rates post-transplantation.

Transplant 40

Transplant Heart Transplant Heart Dysfunction Heart Failure 40

Stroke Journal

JANUARY 30, 2025

Introduction:Intraparenchymal transplantation (tx) of human neural stem cells is in clinical trial for chronic ischemic stroke, but the mechanisms of action are unknown. Most NR1-treated rats (94%) exhibited a new cortical T2-FLAIR signal, associated with positive outcomes, compared to 33% in the vehicle group.

Transplant 40

Transplant Stroke Strokes Outcomes 40

Frontiers in Cardiovascular Medicine

MARCH 7, 2024

Background Belt electrode skeletal muscle electrical stimulation (B-SES) is an emerging therapy anticipated to yield more favorable outcomes than conventional neuromuscular electrical stimulation (NMES), owing to its larger stimulation area. However, information on its efficacy and safety in patients with heart failure remains limited.

Heart Failure 124

Heart Failure Obesity Heart Transplant Transplant 124

HCPLive

MAY 21, 2024

Ashley Malliett, DMSc, MPAS, PA-C, discusses the importance of timely diagnosis and initiated care, as well as contraindications for transplants and LVAD.

Heart Failure 52

Heart Failure Transplant Outcomes 52

Circulation

MARCH 11, 2024

Hematopoietic stem cell transplantation can cure various disorders but poses cardiovascular risks, especially for elderly patients and those with cardiovascular diseases. Cardiovascular evaluations are crucial in pretransplantation assessments, but guidelines are lacking.

Transplant 45

Transplant Cardiovascular Disease Atrial Fibrillation Pediatrics 45

Cardiology Update

APRIL 25, 2024

The primary endpoint was a composite of all-cause mortality, left ventricular assist device (LVAD)/heart transplantation, HF hospitalizations, worsening HF, and KCCQ score changes. Among patients with HFpEF, those who received the shunt experienced poor outcomes than those who did not.

Heart Failure 98

Heart Failure Heart Transplant Transplant Research 98