Science Daily - Stroke

MARCH 28, 2024

A stroke often impacts a person's ability to move their lower body from the hips down to the feet. But now, researchers are exploring new treatment methods to help bridge the service delivery gap, and recovery outcomes, for patients after a stroke.

Quality of Life 109

Quality of Life Stroke Strokes Research 109

DAIC

MAY 14, 2024

UVA Health's Karen Johnston, MD, the SHINE trial leader, was pleased to see the new insights into best practices for stroke care. These data from the SHINE trial continue to inform the national stroke community about potential approaches to treating hyperglycemic stroke patients to assure better outcomes,” she said.

Stroke 105

Stroke Strokes Thrombolysis Hemorrhage 105

Heart BMJ

MAY 10, 2024

Objective The management of blood pressure (BP) in acute ischaemic stroke remains a subject of controversy. This investigation aimed to explore the relationship between 24-hour BP patterns following ischaemic stroke and clinical outcomes. to 1.10), 0.70 (0.53 to 0.93), 0.64 (0.47 to 0.86) and 0.47 (0.33 to 1.10), 0.70 (0.53

Blood Pressure 52

Blood Pressure Outcomes Stroke Strokes 52

Science Daily - Heart Disease

JULY 22, 2024

A new study has identified new genetic and molecular risk factors that may reveal new pathways for treating patients after they experience their first stroke. The study identified CCL27 and TNFRSF14, two proteins that are associated with subsequent MACE, but not initial strokes.

Stroke 104

Stroke Strokes Risk Factors Outcomes 104

Cardiovascular Diabetology

JUNE 17, 2024

Elevated plasma glucose levels are common in patients suffering acute ischemic stroke (AIS), and acute hyperglycemia has been defined as an independent determinant of adverse outcomes. The impact of acute-to-c.

Stroke 59

Stroke Strokes Outcomes Diabetes 59

Science Daily - Stroke

MAY 6, 2024

A new study has revealed that areas of age-related damage in the brain relate to motor outcomes after a stroke -- a phenomenon that may be under-recognized in stroke research.

Stroke 101

Stroke Strokes Research Outcomes 101

DAIC

FEBRUARY 8, 2024

Image courtesy: Getty Images christine.book Thu, 02/08/2024 - 15:53 February 8, 2024 — The latest late-breaking science from the second day of the American Stroke Association ’s International Stroke Conference , ISC 2024 , shed light on the use of artificial intelligence ( AI ) to help guide treatment decisions for stroke patients.

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Stroke Strokes Research Heart attacks 105

Medical Xpress - Cardiology

MAY 16, 2024

Early identification of stroke type could be key to harnessing the benefits of very early in-ambulance blood pressure lowering treatment in patients with suspected acute stroke, according to new research.

Blood Pressure 75

Blood Pressure Stroke Strokes Outcomes 75

DAIC

MAY 7, 2024

A stroke often leads to motor impairment, which is traditionally linked to the extent of damage to the corticospinal tract (CST), a crucial brain pathway for motor control. However, stroke recovery outcomes aren't fully predicted by damage to the CST, suggesting other factors are at play.

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Stroke Strokes Research Public Health 105

DAIC

JUNE 4, 2024

Stroke recovery is a challenging process that extends for months after hospital discharge. To improve outcomes and be in compliance with new regulations, it's crucial to better identify and address these issues during the recovery period. After the stroke, I had new prescriptions, and this was the first obstacle for me.

Stroke 115

Stroke Strokes Innovation Research 115

Journal of the American Heart Association

DECEMBER 8, 2023

However, the association of FAR with large artery atherosclerosis (LAA) stroke is still unknown. This study was conducted to evaluate the association between FAR levels and clinical outcomes in patients with acute LAA stroke.Methods and ResultsA total of 809 patients within 72 hours of LAA stroke were included and followed up to 1 year.

Atherosclerosis 45

Atherosclerosis Stroke Strokes Outcomes 45

Stroke Journal

OCTOBER 27, 2023

Stroke, Volume 54, Issue 12 , Page 3202-3213, December 1, 2023. The Stroke Treatment Academic Industry Roundtable XII included a workshop to discuss the most promising approaches to improve outcome from acute stroke. The workshop brought together representatives from academia, industry, and government representatives.

Academic 40

Academic Stroke Strokes Outcomes 40

Cardiology Update

MARCH 25, 2024

Left main coronary artery disease (CAD) and diabetes pose significant challenges in cardiovascular care, often leading to adverse outcomes. Preliminary evidence from trials focusing on patients with multivessel disease has hinted at diabetes as a potential modifier of treatment outcomes.

Diabetes 122

Diabetes Coronary Artery Bypass Graft Outcomes Coronary Artery Disease 122

Med Page Today

SEPTEMBER 25, 2024

(MedPage Today) -- A dedicated temperature management machine dampened the risk of fever for stroke patients in the intensive care unit (ICU), though this did not translate into better functional outcomes months later in the INTREPID randomized.

ICU 52

ICU Stroke Strokes Outcomes 52

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP163-ATP163, February 1, 2024. Background and aims:Recent studies suggest that oral anticoagulant (OAC) use prior to stroke is associated with better functional outcomes after ischaemic stroke, but worse outcomes after non-traumatic intracerebral haemorrhage (ICH).

Stroke 40

Stroke Strokes Outcomes Atrial Fibrillation 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP53-AWMP53, February 1, 2024. However, the role of neighborhood deprivation in long-term outcomes following acute brain injury remains understudied. We tested the hypothesis that neighborhood deprivation leads to unfavorable long-term functional outcomes following acute ischemic stroke (AIS).Methods:We

Outcomes 40

Outcomes Stroke Strokes Document 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AHUP3-AHUP3, February 1, 2024. However, the role of neighborhood deprivation in long-term outcomes following acute brain injury remains understudied. We tested the hypothesis that neighborhood deprivation leads to unfavorable long-term functional outcomes following acute ischemic stroke (AIS).Methods:We

Outcomes 40

Outcomes Stroke Strokes Document 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP203-AWP203, February 1, 2024. A total of 4353 patients who underwent endovascular treatment for acute ischemic stroke between January 2016 and December 2020 were included in the study. The primary outcome measure was good outcome at discharge, defined as a modified Rankin Scale score of 0-2.Results:Of

Stroke 40

Stroke Strokes Outcomes Laboratory 40

Med Page Today

JUNE 14, 2024

(MedPage Today) -- For stroke patients, late administration of tenecteplase improved clinical outcomes in situations in which thrombectomy was not available immediately, according to the Chinese TRACE-III trial. Patients with ischemic stroke due.

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Stroke Strokes Outcomes 74

Med Page Today

FEBRUARY 20, 2024

(MedPage Today) -- For acute ischemic stroke within 48 hours of onset, the novel sublingual combination of edaravone (Radicava) with dexborneol appeared to dramatically improve functional outcomes in the phase III TASTE-SL trial from China.

Stroke 97

Stroke Strokes Outcomes 97

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP230-ATP230, February 1, 2024. Introduction:Atrial fibrillation (AF) and cancer are both independently associated with worse outcomes in patients with acute ischemic stroke. Few studies have evaluated the impact of AF on outcomes of cancer-related stroke.

Cancer 40

Cancer Atrial Fibrillation Stroke Strokes 40

Stroke Journal

DECEMBER 14, 2023

Stroke, Ahead of Print. BACKGROUND:Iron status has been associated with functional outcomes after ischemic stroke (IS). We acquired summary statistics data sets for functional outcomes following IS from the gene-wide association study meta-analysis conducted by the Genetics of Ischemic Stroke Functional Outcome Consortium.

Outcomes 40

Outcomes Stroke Strokes Biomarkers 40

Journal of the American Heart Association

NOVEMBER 28, 2023

We investigated the impact of vasoregulatory autoantibodies on clinical outcome after ischemic stroke.Methods and ResultsData were used from thePROSCIS‐B(Prospective Cohort With Incident Stroke–Berlin). We included 491 patients with ischemic stroke with data on autoantibody levels and outcome. 3.6]; odds ratio, 1.8 [95%

Outcomes 40

Outcomes Stroke Strokes Myocardial Infarction 40

The New England Journal of Medicine

JUNE 13, 2024

In this trial from China involving 1412 patients with acute ischemic stroke presenting within 4.5 hours, the percentage who had an excellent functional outcome at 90 days was 79.5% with reteplase and 70.4% with alteplase.

Stroke 75

Stroke Strokes Outcomes 75

Med Page Today

MAY 8, 2024

(MedPage Today) -- In patients with acute stroke and a large infarct of unrestricted size, thrombectomy and medical care led to better functional outcomes and lower mortality compared with medical care alone, the prospective randomized LASTE trial.

Stroke 98

Stroke Strokes Outcomes 98

Journal of the American Heart Association

FEBRUARY 13, 2024

BackgroundInformation on the long‐term prognosis in patients with isolated thalamic stroke is sparse. The Functional Independence Measure and modified Rankin Scale were used to assess functional outcomes. A total of 297 patients were included, consisting of 235 with ischemic and 62 with hemorrhagic stroke.

Stroke 40

Stroke Strokes Outcomes Hemorrhage 40

DAIC

MAY 15, 2024

In the meta-analysis of seven randomized trials, published in JSCAI and presented at the 2024 EuroPCR conference in Paris, France, researchers compared the outcomes of 7,785 patients undergoing TAVR (a procedure that delivers a new aortic valve into the heart through a catheter) to those undergoing SAVR for severe aortic stenosis.

Aortic valve 105

Aortic valve TAVR Outcomes Aortic 105

Cardiology Update

FEBRUARY 11, 2024

The NOTION trial, a pioneering study, sought to compare the long-term clinical and bioprosthesis outcomes of Transcatheter Aortic Valve Implantation (TAVI) versus Surgical Aortic Valve Replacement (SAVR) in patients with severe aortic valve stenosis (AS) at lower surgical risk. Severe SVD was defined by specific criteria.

Aortic valve 124

Aortic valve Aortic Outcomes Thrombosis 124

Journal of the American Heart Association

FEBRUARY 23, 2024

The primary outcome was a poor clinical outcome (modified Rankin Scale score, 3–6) at 90 days. The secondary outcome was a composite end point event (cardiovascular death, nonfatal myocardial infarction, nonfatal stroke) at 90 days. A total of 303 patients were included, of whom 94 (31.0%) had a residual cardiac thrombus.

Outcomes 40

Outcomes Stroke Strokes Myocardial Infarction 40

Journal of the American Heart Association

MARCH 8, 2024

In our study population of 1000 thrombectomy‐eligible patients (513 women; median age, 77 years [interquartile range, 67–84]), IVT emerged as a predictor of favorable functional outcome (modified Rankin Scale score, 0–2) independent of modified mTICI score (adjusted odds ratio, 0.49 [95% CI, 0.32–0.75];P=0.001). 0.75];P=0.001).

Thrombolysis 45

Thrombolysis Outcomes Stroke Strokes 45

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP246-AWP246, February 1, 2024. Introduction:The CHA2DS2-VASC score is used to predict stroke in people with atrial fibrillation (AF). CHA2DS2-VASC score (ranging from 0-9) was estimated based on comorbidities documented in hospital data as of the time of acute stroke/TIA.

Stroke 40

Stroke Strokes Outcomes Quality of Life 40

Medical Xpress - Cardiology

JULY 15, 2024

Overall rates of long-term survival following stroke are improving, but Black individuals experience worse long-term outcomes compared to white individuals, according to University of Cincinnati research published online July 15 in Neurology.

Stroke 75

Stroke Strokes Research Outcomes 75

Stroke Journal

MARCH 21, 2024

Stroke, Ahead of Print. BACKGROUND:Patient-reported outcome measures (PROMs) describe health status from the perspective of the patient. There is growing interest in incorporating PROMs into clinical trials, but the extent that such measures are used in contemporary stroke trials is uncertain.

Stroke 40

Stroke Strokes Outcomes Quality of Life 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP164-AWP164, February 1, 2024. Introduction:Patients who have had hemorrhagic strokes experience psychological and functional deficits after hospital discharge. Social Determinants of Health (SDoH) can also impact outcomes.

Hemorrhage 40

Hemorrhage Stroke Strokes Outcomes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATMP58-ATMP58, February 1, 2024. Objectives:To determine the relationship between patient-reported outcome measures (PROMs) and volumetric biomarkers assessed on clinical imaging in acute ischemic stroke (AIS).Background:AIS Background:AIS is a leading cause of long-term disability.

Stroke 40

Stroke Strokes Outcomes Biomarkers 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP77-ATP77, February 1, 2024. had worse outcomes. had worse outcomes. Figure)Conclusions:mRS, BI, and NIHSS outcomes as early as days 2 and 4 post-stroke correlate strongly with their longterm, 3m outcome rank ordering but only moderately with their absolute values.

Stroke 40

Stroke Strokes Outcomes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP272-AWP272, February 1, 2024. Background:Estimated glucose disposal rate (eGDR), a simple and noninvasive measure of insulin resistance, has been proven to be an independent risk factor for first-time stroke and all-cause mortality. 1.51; P<0.01) functional outcome at one year.

Outcomes 40

Outcomes Stroke Strokes Risk Factors 40