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Background Hypertrophic cardiomyopathy (HCM) is commonly associated with atrial fibrillation (AF), but its impact on outcomes in real-world practice is uncertain. years) were enrolled in the EURObservational Research Programme (EORP) Cardiomyopathy/Myocarditis Registry. Methods Overall, 1739 adult patients with HCM (40.9%
Systematic search conducted without language restrictions from December 1, 2019 to June 31, 2022 on PubMed, EMBASE, Web of Science, Cochrane library, ProQuest Coronavirus Research Database, COVID-19 Living Overview of the Evidence (L-OVE) subset of Episteminokos and the World Health Organization (WHO) Covid-19 databases.
Implantation of an intra-aortic balloon pump (IABP) did not improve 60-day survival or bridge to heart replacement (HRT) therapies in patients with heart failure-cardiogenic shock (HF-CS) compared to standard care, according to a study presented during a Featured Clinical Research session at ACC.25
Digging through decades of data from PubMed, Embase, and ClinicalTrials.gov, researchers pooled all relevant articles published through June 2024 (108k patients) and found that a combination lipid-lowering therapy (LLT) of statins plus ezetimibe led to significantly better CV outcomes compared to statin monotherapy.
Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health
But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. From Research to Real-World Care 🌎 Understand how AI-driven advancements are shaping personalized treatments and patient outcomes.
BackgroundPostoperative blood glucose levels significantly impact outcomes in cardiac surgery patients undergoing extracorporeal circulation (ECC) auxiliary to open heart surgery. While hypoglycemia and hyperglycemia are known risk factors for adverse outcomes, the optimal glycemic range for patients undergoing ECC remains unclear.
18, 2024 — In November, Esperion presented an analysis from the CLEAR Outcomes study focused on patients with Peripheral Artery Disease (PAD) who were unable or unwilling to take statin medications. Bonaca, MD, MPH, FAHA, FACC, CPC Clinical Research. tim.hodson Tue, 12/03/2024 - 16:52 Nov. Bempedoic acid reduced MALE (e.g.
Statement Highlights: A new American Heart Association scientific statement updates more than a decade of research identifying, managing and preventing neurodevelopmental delays and disorders among people with congenital heart disease.
However, the causal link between SCH and cardiovascular outcomes remains unclear due to study design heterogeneity and overreliance on TSH levels. Evidence suggests SCH may exacerbate atherosclerosis and cardiac dysfunction through mechanisms such as increased LDL synthesis, oxidative stress, and impaired vascular endothelial function.
(MedPage Today) -- People who identified as a sexual or gender minority (LGBTQ+) had a higher likelihood of adverse brain health outcomes, cross-sectional data showed. Among nearly 400,000 participants in the All of Us research program, sexual.
Experience-based co-design is an approach that enables patients (service users) and healthcare providers (service delivers) to co-design services and care pathways in partnership to improve health outcomes based on their experience. Traditionally, it was used as a quality improvement technique.
29, 2025 Researchers atOchsner Health, led byHernan Bazan, MD, DFSVS, FACS, have developed a predictive model with a 93% accuracy rate in determining whether urgent carotid-intervention patients will regain functional independence. tim.hodson Thu, 01/30/2025 - 15:31 Jan.
The researchers found that patients who received multi-arterial grafting (MAG) had improved survival over those who received single-arterial grafting (SAG), supporting findings from prior retrospective studies. A study presented at The Society of Thoracic Surgeons 61st Annual Meeting explores findings in more than a million U.S.
Research Highlights: Although giving blood thinners along with clot-busting medication may help in treating heart attacks, it did not improve 90-day outcomes in people with clot-caused strokes. Enrollment in a large clinical trial, which had been.
The purpose of this American Heart Association science advisory is to describe the existing evidence on device-measured sedentary behavior and light-intensity physical activity in relation to cardiovascular health during pregnancy and to make specific calls to action for future research to improve health outcomes and to promote health equity.
Pankaj Garg, MD mtaschetta-millane Fri, 07/12/2024 - 11:14 July 12, 2024 — Researchers have developed a groundbreaking method for analyzing heart MRI scans with the help of artificial intelligence , which could save valuable NHS time and resources, as well as improve care for patients. For more information: www.uea.ac.uk
In a recent study published in the European Heart Journal, researchers investigated the influence of varying degrees and extent of untreated chronic obstructive CAD on TAVR outcomes and longer-term results. For more cardiology research news join our newsletter or follow us on Twitter , Facebook , LinkedIn or Instagram.
milla1cf Mon, 01/29/2024 - 11:00 January 29, 2024 — The Society of Thoracic Surgeons has released late-breaking research scheduled for presentation at the 2024 Annual Meeting taking place January 27 - 29 in San Antonio. They note a substantial increase in the frequency of these surgeries, emphasizing the importance of understanding outcomes.
tim.hodson Mon, 03/31/2025 - 15:39 March 30, 2025 Medtronic has announced late-breaking data on five-year outcomes from the Evolut Low Risk Trial. Allison Family Distinguished Chair of Cardiovascular Research and professor of cardiothoracic surgery at the Houston Methodist Hospital and principal investigator of the trial. Grubb, M.D.,
Getty Images milla1cf Tue, 03/19/2024 - 19:09 March 19, 2024 — The American College of Cardiology ( ACC ) has selected 50 learners for its 2024 – 2025 Clinical Trials Research (CTR) program , of whom 28 structural heart cardiologists and surgeons will participate in the CTR’s new Project REACH.
This sub-study aimed to assess the frequency of both valvular (subclinical leaflet thrombus) and perivalvular (supravalvular, subvalvular, and sinus of Valsalva) thrombus and their potential association with various clinical outcomes. had thrombus at any aortic valve complex. Specifically, 14.2% had perivalvular thrombus.
According to new research from the University of Missouri School of Medicine, the number of mechanical thrombectomies performed at hospitals is not an accurate indicator of patient outcomes.
In a new analysis of national data, researchers at the Richard A. Smith Center for OutcomesResearch at Beth Israel Deaconess Medical Center (BIDMC) estimated that 137 million U.S. and Susan F.
Stanford University School of Medicineled researchers have found that intensive blood pressure (BP) control produces cardiovascular benefits and increases the risk of adverse events in people with chronic kidney disease (CKD).
This study aimed to evaluate the early and mid-term outcomes of transcatheter closure using a double-disc occluder device in a single-center Vietnamese cohort.MethodA prospective descriptive study was conducted at Hanoi Heart Hospital, Vietnam. Data were analyzed using SPSS 20.0.ResultsThe
IntroductionDepression is a significant comorbidity linked to poor subjective and objective health outcomes in cardiac patients. The paucity of data necessitates further research to elucidate the pathophysiological connection between depression and cardiac diseases in the presence of N-terminal pro-brain natriuretic peptide (NT-proBNP).
Explore how investigators leverage NCDR data to test their hypotheses on patient risk factors and outcomes, procedure and treatment trends, diversity, health equity and inclusion, guideline adherence, device, facility and provider characteristics, and quality of care. 25, taking place March 29-31 in Chicago, IL.
Statement Highlights: Peripheral vascular disease (PVD)a condition affecting arteries, veins and the lymphatic systems throughout the bodyhas significant differences in incidence, risk factors, diagnosis, treatment and outcomes in women vs. men.
We wanted to examine our outcomes, and we were pleasantly surprised to find that the freedom from re-intervention was 91% at 10 years and 87% at 20 years. at 5,10,15 and 20 years respectively, the researchers reported. Congenital All Members Clinical Decision-Making Patient Outcomes Quality Improvement at 5 years, 94.3%
However, significant gaps exist in palliative care research related to nonheart failure populations, care partner outcomes, and palliative care implementation in diverse populations.
tim.hodson Wed, 04/16/2025 - 14:19 April 16, 2025 An artificial intelligence (AI) program trained to review images from a common medical test can detect early signs of tricuspid heart valve disease and may help doctors diagnose and treat patients sooner, according to research from the Smidt Heart Institute at Cedars-Sinai. Photo: Getty.
Additionally, these patients can be initiated on newly approved drugs for HFpEF, including SGLT-2 inhibitors (SGLT-2i) and GLP-1 receptor agonists (GLP-1RA) in a timely manner, thereby improving their prognosis and long-term outcomes. “We We are very encouraged with the clinical implication of the study results,” says Dr. Sundaram.
Research teams from Northwestern University Feinberg School of Medicine, New York University and Duke University will work together to assess the accuracy of the AHA’s new PREVENT risk calculator. The new research intends to test it against even larger datasets. The research teams will comprehensively evaluate PREVENT.
A public-private partnership Think Tank, focused on leveraging remote monitoring for cardiac safety in clinical trials, has been announced by the Cardiac Safety Research Consortium, CSRC, to be held Feb. How do health authorities view RPM when assessing outcomes for clinical trials, and what are their key challenges?
Background The present study aimed to critically revise the published literature on clinical outcomes and cost-effectiveness of Inspiris Resilia valve. Full text research articles discussing clinical or cost-effectiveness aspects of Inspiris Resilia bioprosthesis published in English were included in this analysis.
They included randomised controlled trials that enrolled adults undergoing major cardiac surgeries and reported postpericardiotomy syndrome, pericardial effusion and pericarditis as primary or secondary outcomes. We summarised the effects of interventions using relative risks and corresponding 95% CIs.
The past two decades have seen a surge in research aimed at understanding the underlying mechanisms driving this association. Stress has long been associated with substance misuse and substance use disorders (SUDs).
A systematic review highlights the available evidence on the use of intravenous fluid in sickle cell vaso-occlusive crises and reported adverse outcomes.
The research team followed these patients for a median time of 2.4 years after SAVR to assess their outcomes. Secondary outcomes included rates of reoperation, infective endocarditis, stroke, and hospital admissions for heart failure. years after TAVR and 4.9 The primary focus was on 5-year survival rates.
In a study published in Heart Rhythm, researchers from Brigham and Women's Hospital, a founding member of the Mass General Brigham health care system, analyzed real-world clinical data to measure the impact of evidence-based best-practices on patient outcomes for the most common AF procedure: radiofrequency (RF)-based ablation.
Dialysis patients using a more traditional home hemodialysis procedure have lower incidence of cardiovascular disease than patients using a less invasive peritoneal catheter for dialysis at home, according to a study led by a University of Cincinnati College of Medicine researcher.
Hospital-based researchers from Denmark have reported a substantial increase in cardiovascular disease risk among male users of anabolic androgenic steroids (AAS). Long-term health outcomes for AAS users show extreme increases in heart-related health risks.
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