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Data on long-term effects of catheter ablation versus antiarrhythmic drugs (AAD) on health-related quality of life (HRQoL) and atrial fibrillation (AF) burden are limited.
For more information: [link] Related Content: Edwards Evoque Transcatheter Tricuspid Valve Replacement System Receives CE Mark Edwards Announces One-year Data on Transfemoral Transcatheter Tricuspid Valve Replacement Six-Month Outcomes Positive for Transfemoral Tricuspid Valve in Tricuspid Regurgitation Patients Edwards LifeSciences Reports (..)
Although lifestyle changes and risk factor modification are now acknowledged as central components of atrial fibrillation management, the effects of exercise on disease-specific outcomes are still not extensively documented due to few high-quality randomised trials.
Shawn Kwatra, MD, discusses the effects of poorly controlled or severe atopic dermatitis on patients’ quality of life and how to measure patient-reported outcomes.
By integrating a real-time frailty risk score into the electronic medical record (EMR), presenting stroke severity and other variables, we can proactively identify who will benefit from immediate surgery and who may need pre-habilitating before surgery to achieve better outcomes.
In patients with obesity and heart failure with preserved ejection fraction (HFpEF), weekly treatment with tirzepatide over approximately two years reduced the risk of worsening heart failure events, based on findings from the SUMMIT trial.
Simultaneous pancreas-kidney (SPK) transplants are known to improve the quality of life and long-term survival of patients with insulin dependent diabetes and advanced renal disease. Short-term clinical outcomes and predicted cost savings of dd-cfDNA-led surveillance after pediatric heart transplantation. Clin Transplant.
This holistic strategy represents a pivotal step toward mitigating disease progression, improving clinical outcomes, and enhancing the quality of life for patients with CKM syndrome.
Panelists discuss how the approval of dupilumab and subsequent biologics for moderate to severe atopic dermatitis has fundamentally transformed the treatment landscape by providing targeted, effective options with favorable safety profiles that address underlying disease pathways, shifting from symptomatic management toward long-term disease control, (..)
The FDA approval is based on positive results seen in the ATTRibute-CM Phase 3 study, where Attruby significantly reduced death and cardiovascular-related hospitalization, and improved quality of life. The ATTRibute-CM Phase 3 study enrolled 632 participants with symptomatic ATTR-CM, associated with either wild-type or variant TTR.
Background We aimed to evaluate the association between atrial fibrillation (AF) burden, duration and number of episodes with healthcare utilisation and quality of life in patients with early paroxysmal AF without a history of AF. Patients were monitored with an insertable cardiac monitor for 1 year.
Despite improvements in outcomes, older adults with competing comorbidities and geriatric syndromes have suboptimal quality of lifeoutcomes, highlighting the cumulative vulnerability that persists despite valve replacement.
This leads to diminished quality of life and mental health in addition to increased susceptibility to falls. But now, researchers are exploring new treatment methods to help bridge the service delivery gap, and recovery outcomes, for patients after a stroke.
Implementing patient-centered palliative care therapies, including prescribing, adjusting or discontinuing medications as needed, may help control symptoms and improve quality of life for people with heart disease, according to "Palliative Pharmacotherapy for Cardiovascular Disease," a new scientific statement from the American Heart Association, published (..)
Abstract Aim Patient reported outcomes (PROs) provide important insights into patients’ acceptance of their medical devices. This study reports PROs, including device-specific and generic quality of life (QOL) from the ATLAS trial. FPAS and SF-36 were analyzed using ANCOVA.
IntroductionHeart failure (HF) causes high symptom burden and shortens life expectancy. Implementation of Palliative Care (PC) concurrently with cardiologic guidelines-directed medical therapy (GDMT) improves quality-of-life (QoL) more than disease-oriented management alone but is underused.
milla1cf Thu, 05/16/2024 - 15:35 May 16, 2024 — A recent publication in the American Heart Association Circulation highlights a comprehensive investigation to assess the impact of revascularization strategies on the health-related quality of life (HRQoL) of patients suffering from chronic limb-threatening ischemia.
These methods only alleviate symptoms of heart failure and myocardial ischemia and improve patients' quality of life by partially restoring myocardial reperfusion.
Atrial fibrillation (AF) significantly affects patients' health-related quality of life (HRQoL), influencing physical, psychological, and social wellbeing. Despite existing tools, there is a notable lack of AF-specific instruments that comprehensively assess HRQoL and are developed in collaboration with patients from the outset.
Semaglutide, compared to placebo, significantly improved walking distance, symptoms and quality of life in participants with symptomatic peripheral artery disease (PAD) and type 2 diabetes (T2D), according to results of the STRIDE study presented at ACC.25 25 in Chicago and simultaneously published in The Lancet.
Gregg Stone, MD “When you examine the outcomes in patients with heart failure across a broad range of left ventricular ejection fraction, the Ventura interatrial shunt was extremely safe but did not improve outcomes compared with no treatment. Researchers tracked outcomes in each participant for at least one year and up to two years.
Implementing a community first responder (CFR) system, including earlier Basic Life Support and defibrillation, can enhance survival rates and neurological outcomes. It suggests that accessible AEDs, trained CFRs and an integrated emergency response system could improve survival rates and quality of life.
Although this improved survival is a triumph, individuals with trisomy 21 and congenital heart disease have unique and complex care needs in the domains of physical, developmental, and psychosocial health, which affect functional status and quality of life.
Background This review aimed to compare the relative effectiveness of different exercise-based cardiac rehabilitation (ExCR) delivery modes (centre-based, home-based, hybrid and technology-enabled ExCR) on key heart failure (HF) outcomes: exercise capacity, health-related quality of life (HRQoL), HF-related hospitalisation and HF-related mortality.
Early detection through regular heart check-ups, including listening for murmurs, can lead to timely treatment and improved outcomes. The earlier we catch it, the more treatment options we have, and the better the outcome for the patient. Many people with HVD may not experience symptoms until the disease reaches an advanced stage.
We aimed to determine the relationship between the affected hemisphere (right or left) and differences in non-motor outcomes (pain, mood) in patients with acute intracerebral hemorrhage (ICH). The association of ICH laterality with clinical outcomes was estimated using multiple linear regression models.
Introduction:Stroke impairs stroke survivor (SS) quality of life (QoL). Outcome data for QoL was gathered after 6 months. Stroke, Volume 55, Issue Suppl_1 , Page ATP255-ATP255, February 1, 2024. Black SS in the US also endure stress from structural, cultural, and interpersonal racism.
Introduction:Stroke impairs stroke survivor (SS) quality of life (QoL). Outcome data for QoL was gathered after 6 months. Stroke, Volume 55, Issue Suppl_1 , Page AHUP11-AHUP11, February 1, 2024. Black SS in the US also endure stress from structural, cultural, and interpersonal racism.
Harmony TPV system clinical trials demonstrate ease of implant, conformability to the anatomy, and strong clinical and hemodynamic outcomes for congenital heart disease patients up to three years. Food and Drug Administration approval of the system in 2021. Harmony TPV U.S. For more information, please visit www.Medtronic.com.
BioCardia previously confirmed alignment with the United States Food and Drug Administration (FDA) on the design of the 250-patient randomized, controlled trial and the minimum of 12-month primary composite endpoint of all cause death, reduction in major adverse cardiovascular events, and improvement in quality of life.
Publication date: Available online 29 December 2023 Source: The American Journal of Cardiology Author(s): Lorenzo Braghieri, Arwa Younis, Chadi Tabaja, Pasquale Santangeli, Tyler Taigen, Walid I. Saliba, Oussama M. Wazni, Ayman A.
However, there is a paucity of information regarding the impact of AF on HCM employing validated quality of life (QoL) surveys. Therefore, we evaluated the impact of AF on QoL utilizing patient reported outcome measures (PROMs).
The primary outcome is the GDMT prescription rate score, with secondary outcomes covering the time to full GDMT optimization, patient and clinician satisfaction, time spent on healthcare, and the Kansas City Cardiomyopathy Questionnaire. Digital guideline recommendations for treating clinicians. Original article: Man JP et al.
Lifetime statin treatment increased quality-of-life-adjusted survival in men and women aged ≥70 years with and without previous CVD in the United Kingdom.
Heart failure (HF) is a growing worldwide public health issue affecting 64 million people annually 1 and is associated with high mortality, lower quality of life and reduced physical capacity while placing substantial costs on the healthcare system.
Lilly’s blockbuster GLP-1 tirzepatide appears poised to become the next major HFpEF drug, after topline results from the SUMMIT trial showed that it significantly improved both outcomes and symptoms among patients with heart failure with preserved ejection fraction and obesity.
Patients who achieved early remission with upadacitinib or adalimumab following an inadequate response to methotrexate had less pain/fatigue and better physical quality of life.
ii The DEFINE AFib clinical study enrolled 973 patients using an app-based enrollment feature and characterized the impact of AF burden on patient outcomes and quality of life. By 2030, approximately 12.2 million people in the U.S. will have AF, an irregular and potentially dangerous heart rhythm.
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