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Continuous heart monitoring to evaluate treatment effects in pulmonary hypertension

Open Heart

Background The treatment of pulmonary hypertension (PH) has improved rapidly in recent decades. There is increasing evidence to support the role of early intervention and treatment in affecting clinical outcomes in PH. Methods Patients were compared before and after treatment escalation.

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Prognostic impact of follow-up pulmonary vascular resistance in pulmonary arterial hypertension

Open Heart

Objective Pulmonary arterial hypertension (PAH), caused by pulmonary artery remodelling and increased pulmonary vascular resistance (PVR) due to an unknown mechanism, is an intractable disease with a poor prognosis. The primary outcome was death or lung transplantation.

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Abstract Sa1109: Aerobic Capacity of Adults with Fontan Palliation: Disease-specific Reference Values and Relationship to Outcomes

Circulation

Background:Patients with Fontan palliation have reduced aerobic capacity because of impaired cardiac, pulmonary, and skeletal muscle function. We assessed the correlates of predicted peak VO2, and the relationship between predicted peak VO2quartiles and cardiovascular outcomes (death/transplant).Results:Of 15.2 - 23.9)

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Transcatheter Palliation With Pulmonary Artery Flow Restrictors in Neonates With Congenital Heart Disease: Feasibility, Outcomes, and Comparison With a Historical Hybrid Stage 1 Cohort

Circulation: Cardiovascular Interventions

Background:Neonates with complex congenital heart disease and pulmonary overcirculation have been historically treated surgically. Pulmonary arteries grew adequately for age, and devices were easily removed without complications. Circulation: Cardiovascular Interventions, Ahead of Print. kilograms [IQR, 2.1–3.3]) months (IQR, 4.0–10.8),

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Trends in Ductus Arteriosus Stent Versus Blalock?Taussig?Thomas Shunt Use and Comparison of Cost, Length of Stay, and Short?Term Outcomes in Neonates With Ductal?Dependent Pulmonary Blood Flow: An Observational Study Using the Pediatric Health Information Systems Database

Journal of the American Heart Association

BackgroundThe modified Blalock‐Taussig‐Thomas shunt is the gold standard palliation for securing pulmonary blood flow in infants with ductal‐dependent pulmonary blood flow. Intervention was not significantly associated with odds of 30‐day transplant‐free survival (OR,1.18 [95% CI, 0.70–1.99])

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Uric acid in advanced heart failure: relation to central haemodynamics and outcome

Open Heart

Cox models were created to investigate if UA was a significant predictor of adverse outcome where log1.1(UA) UA) was used to estimate the effect on outcome associated with a 10% increase in UA levels. Median UA was 0.48 (0.39–0.61) mmol/L.

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Prognostic value of three iron deficiency definitions in patients with advanced heart failure

European Journal of Heart Failure

Venn diagram of iron deficiency (ID) according to various definitions and associated outcomes. We evaluated three definitions of ID in patients referred for heart transplantation. Methods and results Consecutive patients assessed for heart transplantation at a single UK centre between January 2010 and May 2022 were included.