CardiacWire

MARCH 8, 2024

A landmark NEJM study revealed that many patients with carotid artery disease might have microplastics and nanoplastics (MNPs) embedded in their carotid plaque, and those patients have a massive 4.5-fold of patients had polyethylene in their plaque and 12.1% in patients without MNPs in their plaque. An alarming 58.4%

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Plaque Myocardial Infarction Heart attacks Heart Attack 119

Dr. Paddy Barrett

DECEMBER 19, 2023

You cannot eliminate the plaque entirely, but multiple clinical trials have shown plaque regression using high-intensity cholesterol-lowering treatments, which I have discussed previously. All of these parameters are important and need to be considered when evaluating plaque regression. REVERSAL Investigators.

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Coronary Artery Disease Plaque Exercise Heart attacks 106

Frontiers in Cardiovascular Medicine

MARCH 4, 2024

The complex development of atherosclerosis manifests as intimal plaque which occurs in the presence or absence of traditional risk factors. Coronary computed tomography angiography (CCTA) is the most advanced candidate, with the ability to measure accurately and reproducibly characterize the underlying causal disease itself.

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Plaque Coronary Artery Disease Blood Pressure Cardiovascular Disease 59

Frontiers in Cardiovascular Medicine

MARCH 27, 2025

Main outcomes will include changes from baseline to follow-up in overall knowledge, attitudes, and FBS.ConclusionsWAKE UP trial aims to raise awareness about womes CV disease and promote lifestyle changes.

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Open Heart

MARCH 8, 2024

Objective Coronary CT angiography (CCTA) permits both qualitative and quantitative analysis of atherosclerotic plaque and may be a suitable risk modifier in assessing patients at intermediate risk of atherosclerotic cardiovascular disease. 47 (57%) patients had mixed plaque, which was predictive of MACE (OR 4.68 (95% CI 1.19

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Plaque Stenosis Cardiovascular Disease Strokes 52

MIBHS

JANUARY 15, 2025

Understanding how smoking affects the heart and raises surgery risks can empower individuals to make healthier choices and improve outcomes when surgical intervention is necessary. Inflammation and Plaque Buildup: Smoking damages the endothelium (the inner lining of blood vessels), triggering inflammation.

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Coronary Artery Bypass Graft Blood Clot Blood Pressure Plaque 52

DAIC

DECEMBER 5, 2024

With this new funding, Cleerly will continue to scale its commercial growth and clinical evidence generation, helping health care professionals improve outcomes for patients across the coronary care pathway. Until Cleerly, healthcare providers have had no way to easily and completely assess plaque burden in a non-invasive manner.

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Coronary Artery Disease Medicare Plaque Technology 52

DAIC

DECEMBER 13, 2023

MILLER, PHD, LED THE DEVELOPMENT OF A NEW "ATHEROSCLEROSIS ATLAS" THAT DETAILS, AT THE LEVEL OF INDIVIDUAL CELLS, CRITICAL PROCESSES RESPONSIBLE FOR FORMING THE HARMFUL PLAQUE BUILDUP THAT CAUSES HEART ATTACKS, STROKES AND CORONARY ARTERY DISEASE. Over time, fatty plaques build up inside the arteries, where they can slow blood flow.

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Heart attacks Heart Attack Atherosclerosis Strokes 105

Medical Xpress - Cardiology

NOVEMBER 13, 2024

While carotid endarterectomy, a surgical procedure to remove plaque from the carotid artery, has been shown to reduce the risk of stroke, not all patients experience the same outcomes, according to a new study led by researchers from the Penn State College of Medicine.

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Journal of the American Heart Association

FEBRUARY 26, 2025

BackgroundPlaque progression (PP) is critical between subclinical atherosclerosis and plaque rupture. Intensive control of sdLDLC along with other risk factors should be considered to mitigate PP and improve cardiovascular outcomes. Journal of the American Heart Association, Ahead of Print.

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Ultrasound Plaque Cholesterol Coronary Artery Disease 56

DAIC

FEBRUARY 26, 2025

A key element of Heartflows approach is close collaboration with clinical teams to improve patient experiences, create efficient care pathways and reach more patients with personalized insights, ensuring the best possible outcomes. In the U.S., 1 Many of the estimated 18 million adults in the U.S.

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DAIC

APRIL 11, 2024

The study, called IVUS-DCB, is the first randomized controlled trial to demonstrate the clinical benefits of using IVUS in angioplasty procedures for peripheral artery disease (PAD), a condition in which plaque builds up in arteries in the legs.

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Peripheral Arterial Disease Ultrasound Angioplasty Plaque 116

Stroke Journal

DECEMBER 8, 2023

BACKGROUND:Aortic arch plaques are associated with an increased risk of ischemic stroke in patients with cryptogenic stroke or prior embolic events. Arch plaques were assessed by suprasternal transthoracic echocardiography; plaques ≥4 mm in thickness were classified as large plaques. Stroke, Ahead of Print.

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MIBHS

MARCH 31, 2025

This blockage is often caused by a blood clot or the buildup of plaque in the coronary arteries, which supply the heart with oxygen-rich blood. Raising awareness and taking proactive steps can ensure the best possible outcomes for those at risk of heart-related conditions.

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DAIC

JULY 19, 2024

The study evaluated the ability of the Fat Attenuation Index (FAI) Score on routine CCTA to predict cardiovascular outcomes in different socioeconomic classes, ethnicity groups, and in the presence or absence of obstructive coronary artery disease (CAD).

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Coronary Artery Disease Academic Plaque Research 111

DAIC

JULY 23, 2024

Brittany Weber, MD, PhD , of Brigham and Women’s Hospital, is the 2024 YIA winner for her abstract, "The Frequency, Prevalence, And Outcomes Of Incidentally Detected Coronary Artery Calcium Using Artificial Intelligence Analysis Among Patients With Immune Mediated Inflammatory Diseases.”

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Chest Pain Plaque Coronary Artery Disease Ischemia 105

DAIC

JUNE 4, 2024

I am excited about the potential of the FAI-Score biomarker, which has promising prognostic value beyond existing CT-based methods such as plaque, calcium scoring, and CAD-RADS based interpretation." Details of the study, included in a written statement issued by Caristo Diagnostics, follow. fold higher risk for cardiac mortality and 5.5-fold

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Technology Heart attacks Heart Attack Coronary Artery Disease 116

DAIC

NOVEMBER 8, 2024

Procedures that previously required the use of two different devices can now be performed in a single procedure using a single device, simplifying workflows and procedures and potentially reducing the risk and improving outcomes for patients who might otherwise face multiple complex interventions. Patients will be followed for 12 months.

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Innovation Peripheral Arterial Disease Technology Ultrasound 52

Cardiovascular Diabetology

JULY 10, 2024

Methods This study comprised prespecified and post-hoc analyses of the EMPA-REG OUTCOME trial in which 7020 people with type 2 diabetes (T2D) and cardiovascular disease [mostly atherosclerotic (ASCVD)] were randomized to empagliflozin or placebo and followed for a median 3.1

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Myocardial Infarction Coronary Artery Bypass Graft Outcomes Plaque 52

Dr. Smith's ECG Blog

JULY 11, 2024

The scan did not find PE, but showed evidence of coronary plaque: There are areas of dense white in the LAD (red and blue circles) and in the first diagonal (green circle). A chest x-ray in the ED found bilateral pleural effusions. The patient’s BNP was 738, and his D-dimer was elevated, prompting a CT scan to rule out PE.

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DAIC

JANUARY 16, 2024

“The CHEETAH findings suggest that continuous aspiration with CAT RX should be a key consideration when high thrombus burden plaque is encountered given that removing the thrombus improves perfusion. We believe this can lead to better outcomes for the patient,” said James F. Benenati, M.D., FSIR , chief medical officer at Penumbra.

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DAIC

APRIL 12, 2024

The Acolyte Image Guided Crossing and Re-Entry Catheter System aims to overcome these challenges by providing clinicians with this breakthrough device that has enhanced visualization and navigation capabilities, ultimately improving CTO crossing, procedural success rates, and patient outcomes. "We

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Technology Cardiovascular Interventions Coronary Artery Disease Innovation 111

NEJM Journal Watch - Cardiology

APRIL 11, 2024

However, many of the events prevented were subsequent PCIs, so future studies focused on death and myocardial infarction outcomes are needed.

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Dr. Smith's ECG Blog

NOVEMBER 15, 2023

MINOCA may be due to: coronary spasm, coronary microvascular dysfunction, plaque disruption, spontaneous coronary thrombosis/emboli , and coronary dissection; myocardial disorders, including myocarditis, takotsubo cardiomyopathy, and other cardiomyopathies. Thus, intracoronary imaging modalities are crucial in this setting. From Gue at al.

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DAIC

APRIL 6, 2024

However, in an exploratory analysis of outcomes, treated patients had fewer heart attacks and heart-attack deaths than patients in the control group at six months, he said. A previous study showed that a single infusion of CSL112 reduced the amount of LDL cholesterol in arterial plaque by as much as 50%.

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Heart attacks Heart Attack Cholesterol Blood Clot 98

Dr. Paddy Barrett

DECEMBER 26, 2023

Rather than just aiming to get ‘Healthy’ this year, how about setting clear targets for improvement that are highly correlated to positive health outcomes? Muscle Strength Muscle strength and muscle mass are closely linked to improved longevity and better health outcomes. Subscribe now V02 Max. You decide. You measure.

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Coronary Artery Disease Plaque Heart attacks Heart Attack 103

DAIC

FEBRUARY 4, 2025

Over time, this plaque can gradually narrow the arteries. The stark disparities in PAD awareness and outcomes are particularly pronounced among Black and Hispanic adults. Kick off the conversation with your doctor: Early diagnosis and treatment can prevent severe outcomes. This is a common sign of PAD and should not be ignored.

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Peripheral Arterial Disease Blood Pressure Risk Factors Diabetes 52

DAIC

OCTOBER 1, 2024

tim.hodson Tue, 10/01/2024 - 10:50 PHOTO CAPTION: The Elucid PlaqueIQ user interface is a fully interactive visualization of the patient’s coronary anatomy, showing specific plaque type and amount across various views to inform physician assessment of risk and patient-specific treatment pathway.

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Cardiovascular Disease Plaque Quality of Life Myocardial Infarction 52

DAIC

JANUARY 9, 2024

Improvements in outcomes following peripheral vascular intervention have lagged compared to other endovascular treatments, such as percutaneous coronary intervention. It provides detailed information about the vessel wall, plaque composition, and blood flow characteristics, enabling more accurate diagnosis and treatment planning.

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Peripheral Arterial Disease Ultrasound Angioplasty Interventional Cardiology 105

DAIC

MAY 16, 2024

A new joint guideline from the American Heart Association (AHA), the American College of Cardiology (ACC) and nine other medical societies reports early diagnosis and treatment of peripheral artery disease is essential to improve outcomes and reduce amputation risk, heart attack, stroke and death for people with Peripheral Artery Disease (PAD).

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Peripheral Arterial Disease Exercise Ischemia Quality of Life 105

Physiologically Speaking

APRIL 10, 2024

people from the general population), coronary artery calcium scores (CACS) are higher, indicating more calcification and the presence of atherosclerotic plaques. Calcified plaques are known to be more stable and less prone to rupture and lead to a heart attack. When comparing athletes to control groups (i.e., hours per week).

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Atherosclerosis Plaque Exercise Cardiovascular Disease 52

DAIC

FEBRUARY 3, 2025

Lp(a) is emerging as an important, yet under-recognized, potential risk factor for cardiovascular disease due to its ability to promote the development of plaques within artery walls, clot formation and aortic valve calcification. The development of the Tina-quant Lipoprotein (a) Gen.2

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Stroke Journal

JANUARY 30, 2025

The primary outcomes were the percentage change in plaque burden and plaque response (plaque regression >5%) rate. The second outcome was the percentage change in stenosis degree. The patients were divided into two groups: those with (evolucomab+) or without (evolocumab-) evolocumab add-on therapy.

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Stenosis Plaque Outcomes Strokes 40

MIBHS

FEBRUARY 28, 2025

Specific genetic variants, such as those affecting cholesterol metabolism, can increase the likelihood of plaque buildup in the arteries. Personalized medicine allows healthcare providers to prescribe medications and treatment regimens based on specific genetic information, improving treatment outcomes.

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Circulation

NOVEMBER 11, 2024

The primary outcome was the prevalence of carotid artery plaques assessed by ultrasound. Secondary outcomes included changes in NMR-derived lipoprotein subclasses and their mediation effects on carotid plaque. Fish oil supplementation was significantly associated with reduced prevalence of carotid plaques (P=0.023).

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Frontiers in Cardiovascular Medicine

AUGUST 6, 2024

Myocardial infarction (MI) stands at top global causes of death in developed countries, owing mostly to atherosclerotic plaque growth and endothelial injury-induced reduction in coronary blood flow. While early reperfusion techniques have improved outcomes, long-term treatment continues to be difficult.

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Myocardial Infarction Plaque Physiology Cardiovascular Disease 52

Dr. Paddy Barrett

SEPTEMBER 5, 2023

Share Let’s first state our goal when we are in the business of ‘Heart Disease Prevention’: To delay the onset of coronary artery disease (atherosclerosis/plaque) that might rupture and cause a heart attack. And the less plaque you have, the lower the risk of a heart attack. And it’s also WAY more common.

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