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Guideline Highlights: The new joint guideline from the American Heart Association and the American College of Cardiology provides recommendations to guide clinicians in the treatment of patients with lower extremity peripheralarterydisease (PAD) and.
The study, called IVUS-DCB, is the first randomized controlled trial to demonstrate the clinical benefits of using IVUS in angioplasty procedures for peripheralarterydisease (PAD), a condition in which plaque builds up in arteries in the legs.
Getty Images milla1cf Mon, 02/12/2024 - 15:22 February 12, 2024 — Sensome , a company pioneering the connected medical device revolution with the world’s smallest biological tissue sensor, announced today enrollment of the first patients into a feasibility clinical study using the Clotild Smart Guidewire in peripheralarterydisease (PAD).
18, 2024 — In November, Esperion presented an analysis from the CLEAR Outcomes study focused on patients with PeripheralArteryDisease (PAD) who were unable or unwilling to take statin medications. tim.hodson Tue, 12/03/2024 - 16:52 Nov. It was presented on behalf of all authors by Marc P.
A new joint guideline from the American Heart Association (AHA), the American College of Cardiology (ACC) and nine other medical societies reports early diagnosis and treatment of peripheralarterydisease is essential to improve outcomes and reduce amputation risk, heart attack, stroke and death for people with PeripheralArteryDisease (PAD).
METHODS:The AHA, through its Epidemiology and Prevention Statistics Committee, continuously monitors and evaluates sources of data on heart disease and stroke in the United States and globally to provide the most current information available in the annual Statistical Update with review of published literature through the year before writing.
Ongoing studies will yield important insights regarding improving care and outcomes in this highrisk group. Journal of the American Heart Association, Ahead of Print. The 1year incidence of cardiovascular events was 5.6 per 100 patientyears and limb events was 7.0 The incidence of death and clinical events in our cohort is high.
Background Multiple clinical studies have found a significant correlation between elevated galectin-3 (Gal-3) in circulation and the diagnosis and severity of peripheralarterialdisease (PAD). The current study used the Mendelian randomization (MR) technique to evaluate the possible causal relationship between Gal-3 and PAD.
Peripheralarterydisease (PAD) continues to increase in prevalence worldwide due to risk factors such as advanced age, diabetes mellitus, and obesity. Critical limb ischemia (CLTI) is the advanced form of PAD that can result in a lack of healing and limb loss as the most devastating consequence.
Semaglutide, compared to placebo, significantly improved walking distance, symptoms and quality of life in participants with symptomatic peripheralarterydisease (PAD) and type 2 diabetes (T2D), according to results of the STRIDE study presented at ACC.25 25 in Chicago and simultaneously published in The Lancet.
tim.hodson Fri, 03/14/2025 - 16:12 SCAI Scientific Sessions 2025 will take place May 1 to 3, attheWalter E. Washington Convention Center in Washington, DC.
Bob Ross, PA-C, shares expert insights on early PAD detection, updated guidelines, and practical tools to improve vascular health outcomes from CAPP 2024.
Peripheralarterialdisease (PAD) is the third leading cause of atherosclerotic morbidity after coronary heart disease and stroke yet is widely underdiagnosed and undertreated. Treatment of risk factors such as diabetes and cigarette smoking can benefit patients with PAD.
Studies were included if they compared DCBA and POBA in PAD patients, focusing on primary outcomes such as target lesion revascularization (TLR), primary patency (PP), all-cause mortality (ACM), and amputation. Secondary outcomes included restenosis, late lumen loss (LLL), and major adverse events (MAE).ResultsSixteen
3, 2025 Today, PeripheralArteryDisease (PAD)affects 10 million Americans and is the most common cause of limb amputation outside of trauma. PeripheralArteryDisease (PAD) is a chronic condition where plaquea sticky substance made of fat and cholesterolbuilds up in the arteries that carry blood to your legs.
There is significant variability in the efficacy and safety of oral P2Y12 inhibitors, which are used to prevent ischemic outcomes in common diseases such as coronary and peripheralarterialdisease and stroke. Circulation, Ahead of Print.
Given this dismal outcome, the prognosis of CLTI is worse than most cancers.3,4 The global burden of peripheralarterydisease. Decline in functional performance predicts later increased mobility loss and mortality in peripheralarterialdisease. The global burden of peripheralarterydisease.
Circulation: Cardiovascular Quality and Outcomes, Ahead of Print. Peripheralarterydisease (PAD) is an atherosclerotic condition that affects a growing number of individuals worldwide, with estimates exceeding 220 million.
There are discrepancies in the literature regarding whether vorapaxar alleviates ischemic outcomes and increases bleeding in patients with peripheralarterialdisease (PAD).Purpose:The Introduction:Vorapaxar is an inhibitor of protease-activated receptor-1 (PAR1) and primarily blocks thrombin mediated platelet activation.
We believe the tools, resources, and information shared at the meeting will provide the healthcare community with greater expertise to improve patient outcomes and also connect with their interventional cardiology colleagues,” said SCAI President George D. Dangas, MD, PhD, MSCAI , Icahn School of Medicine - Mt.
Publication date: Available online 5 August 2024 Source: The American Journal of Cardiology Author(s): Sameh Sayfo, Zachary P. Rosol, David Fernandez Vazquez, Mufaddal Mamawala, Blake M. Bruneman, Sarah G. Weideman, Kennedy S. Adelman, Minseob Jeong, Bala Ramanan, Shirling Tsai, Nicolas W. Shammas, Peter P. Monteleone, Aravinda Nanjundappa, Hung B.
Publication date: Available online 1 April 2025 Source: The American Journal of Cardiology Author(s): Michael Gao, Angelo Oliva, Raman Sharma, Frank Kalaba, Samantha Sartori, Serdar Farhan, Kenneth Smith, Birgit Vogel, Prakash Krishnan, George Dangas, Roxana Mehran, Annapoorna Kini, Samin Sharma
Procedures that previously required the use of two different devices can now be performed in a single procedure using a single device, simplifying workflows and procedures and potentially reducing the risk and improving outcomes for patients who might otherwise face multiple complex interventions. Patients will be followed for 12 months.
1.02]) after adjustment for baseline factors.ConclusionsComorbid MVD is present in a large and growing number of patients with PAD and is associated with augmented risk for adverse outcomes. Compared with PAD‐only, PAD/MVD was associated with a higher risk for major amputation (odds ratio [OR], 1.30 [95% CI, 1.28–1.32]),
Publication date: Available online 1 May 2024 Source: The American Journal of Cardiology Author(s): Nameer Ascandar, Joseph Hadaya, Nam Yong Cho, Konmal Ali, Yas Sanaiha, Peyman Benharash
Publication date: Available online 26 February 2025 Source: The American Journal of Cardiology Author(s): Mary O. Whipple, Shujun Xu, Dongxue Zhang, Jack Guralnik, Bonnie Spring, Lu Tian, Diane Treat-Jacobson, Lihui Zhao, Michael H. Criqui, Mary M. McDermott
In this week’s View, Dr. Eagle covers various blood pressure parameters and their predictability for peripheralarterialdisease (PAD) and complications, then explores the five-year outcomes of leadless pacemakers.
mtaschetta-millane Mon, 07/29/2024 - 09:16 July 29, 2024 — CorVascular , a leading producer of peripheralarterialdisease (PAD) / peripheral vascular disease (PVD) testing devices, today announced the U.S. Food and Drug Administration (FDA) has cleared its VasoGuard V-Series as Class II medical devices.
This study investigates the association between VTRNA2-1 promoter methylation and clinical outcomes in PAD patients requiring revascularization.Hypothesis:VTRNA2-1 promoter methylation status is associated with clinical outcomes in PAD patients requiring revascularization.Methods:A total of 133 PAD patients requiring revascularization were enrolled.
Venita Chandra, director of vascular surgery, Stanford University School of Medicine, showed that DA followed by DCB achieved a significantly lower provisional stent rate with comparable safety and efficacy outcomes compared to standard predilatation prior to DCB, making it a viable alternative for treating long and highly calcified lesions.
A study in the Journal of Vascular Surgery revealed that adding FFRCT assessments to patient workups prior to peripheralarterydisease surgeries has a massive impact on coronary arterydisease detection, treatments, and long-term outcomes.
Improvements in outcomes following peripheral vascular intervention have lagged compared to other endovascular treatments, such as percutaneous coronary intervention. Ongoing collaboration among these specialties is paramount to improving outcomes for patients worldwide.” Tam, MD, MBA, FSIR.
Furthermore, due to increasing patient complexity of management secondary to comorbid conditions, such as cardiovascular disease, the management of peripheralarterydisease associated with DFUs has become increasingly difficult, and care delivery is often episodic and fragmented.
The primary outcome was a composite of inhospital adverse events. Associations between multimorbidity patterns and outcomes were evaluated using multivariableadjusted logistic regression models. years]) admitted to the China Chest Pain Center Database between 2016 and 2021. Among 9570 patients, 50% (n=4789) had multimorbidity.
CLTI is the most severe form of peripheralarterialdisease (PAD), estimated to affect 11% of the 200 million people suffering from PAD globally. The Freesolve BTK RMS is designed for individuals suffering from chronic limb-threatening ischemia (CLTI). For more information: www.biotronik.com References: 1 Kwong M.,
Introduction The presence of non-coronary atherosclerosis (NCA) in patients with coronary arterydisease is associated with a poor prognosis. We have studied whether NCA is also a predictor of poorer outcomes in patients undergoing coronary artery bypass grafting (CABG). 2.69], age (HR = 1.35, 95% CI 1.09–1.67,
METHODS:The AHA, through its Epidemiology and Prevention Statistics Committee, continuously monitors and evaluates sources of data on heart disease and stroke in the United States and globally to provide the most current information available in the annual Statistical Update with review of published literature through the year before writing.
Objective To investigate the impact of prior coronary artery bypass grafting (CABG) and coronary lesion complexity on transcatheter aortic valve replacement (TAVR) outcomes for aortic stenosis. 23), which was not associated with better/worse clinical outcomes in patients with prior CABG.
The study aims to evaluate the applicability in the real world of randomised clinical trials (RCT) on antithrombotic treatment in patients with cardiovascular disease (CVD) and peripheralarterydisease (PAD).
An increasing number of studies have shown the impact of social determinants of health (SDoHs) on different cardiovascular outcomes. In the setting of arrhythmias, specific SDoHs can increase the incidence of atrial fibrillation and adversely affect major outcomes in these patients.
BACKGROUND:Rivaroxaban plus aspirin compared with aspirin alone reduced major cardiac and ischemic limb events after lower extremity revascularization (LER) in the VOYAGER PAD (Vascular Outcomes Study of ASA Along With Rivaroxaban in Endovascular or Surgical Limb Revascularization for PeripheralArteryDisease) trial.
Circulation: Cardiovascular Quality and Outcomes, Ahead of Print. Patients who had an myocardial infarction, underwent coronary artery bypass graft (hazard ratio, 1.60 [95% CI, 1.55–1.65]),
Researchers analyzed more than 145 million records covering every adult patient admitted to hospital in England over a nine-year period to establish the risk of long-term health outcomes following a heart attack -- in the largest study of its kind.
Then identified clusters are predicted and tested in the learning set to evaluate their association with outcomes. Clusters were significantly associated with outcomes in derivation and validation datasets, with Cluster 1 having the highest risk, and Cluster 4 the lowest.
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