DAIC

JUNE 18, 2024

A projected rise in heart disease and stroke – along with several key risk factors, including high blood pressure and obesity – is likely to triple related costs to $1.8 This includes a doubling of stroke rates. Obesity rates are expected to climb from 43.1% to 61% of the U.S. population. of the population.

Heart Disease 105

Heart Disease Blood Pressure Strokes Stroke 105

Med Page Today

MARCH 8, 2024

(MedPage Today) -- The FDA approved semaglutide (Wegovy) to reduce the risk of cardiovascular death, heart attack, and stroke in adults with cardiovascular disease and either obesity or overweight, the agency announced on Friday. A GLP-1 receptor.

Heart Disease 141

Heart Disease Heart attacks Heart Attack Obesity 141

Dr. Paddy Barrett

FEBRUARY 21, 2025

For over 50 years, rates of those who are overweight or obese have been rising rapidly. Despite the rise in obesity rates, the growing recognition of it as a global problem and the astronomical sums of money we spend on addressing it, the tide continues to rise. That is until now. The answer is… eye wateringly well.

Obesity 77

Obesity Diabetes Cardiovascular Disease Chronic Disease 77

Med Page Today

MARCH 21, 2024

(MedPage Today) -- Medicare will cover the weight-loss drug semaglutide (Wegovy) under its Part D drug program for patients with overweight or obesity who have preexisting heart disease and need the drug to prevent heart attacks or strokes, the.

Medicare 132

Medicare Heart attacks Heart Attack Obesity 132

Heart BMJ

SEPTEMBER 16, 2024

Obesity is a major global health issue and a leading cause of premature death. The prevalence of obesity has been rising faster than most other known modifiable risk factors. In a Global Burden of Disease analysis, the prevalence of obesity was found to have doubled in more than 70 countries from 1980 to 2013.

Obesity 52

Obesity Blood Pressure BMI Risk Factors 52

Cardiovascular Diabetology

MARCH 7, 2025

Obesity and abnormal lipid metabolism increase the risk of various cardiometabolic diseases, including diabetes, heart disease, and stroke. However, the impact of abdominal obesity (AO) and non-traditional lip.

Obesity 52

Obesity Heart Disease Diabetes Strokes 52

Medical Xpress - Cardiology

JANUARY 21, 2025

Atrial fibrillation, or A-fib, is an irregular heart rhythm that increases a person's risk of stroke, heart failure and even premature death.

Heart Rhythm 75

Heart Rhythm Atrial Fibrillation Obesity Research 75

American Heart News - Heart News

NOVEMBER 11, 2023

Research Highlights: In a large, international clinical trial, people with obesity or overweight but not diabetes taking semaglutide for more than 3 years had a 20% lower risk of heart attack, stroke or death due to cardiovascular disease and lost an.

Obesity 52

Obesity Diabetes Heart attacks Heart Attack 52

Circulation

JUNE 4, 2024

BACKGROUND:Cardiovascular disease and stroke are common and costly, and their prevalence is rising. to 26.8%) and obesity (43.1% to 3.8%), stroke (3.9% Circulation, Ahead of Print. in 2020 to 61.0% Diabetes (16.3% to 60.6%) will increase, whereas hypercholesterolemia will decline (45.8% Prevalences of coronary disease (7.8%

Risk Factors 81

Risk Factors Cardiovascular Disease Strokes Stroke 81

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. IntroductionClinical risk factors and co‐morbidities in obese male and female ischemic stroke patients with a history of smoking may contribute to differing stroke outcomes.

Obesity 40

Obesity Strokes Stroke Risk Factors 40

Journal of the American Heart Association

DECEMBER 29, 2023

AF increases the risk of stroke, heart failure, dementia, and hospitalization. Obesity significantly increases AF risk, both directly and indirectly, through related conditions, like hypertension, diabetes, and heart failure. However, studies on how obesity affects pharmacologic or interventional AF treatments are limited.

Obesity 45

Obesity Atrial Fibrillation Heart Failure Pharmacology 45

Cardiovascular Diabetology

MARCH 11, 2025

Numerous studies have investigated the effect of an integrated index that combines the triglycerideglucose (TyG) index with various obesity indicators on stroke incidence. However, how to use the TyG index an.

Strokes 52

Strokes Stroke Obesity Research 52

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. IntroductionRecombinant tissue plasminogen activator (rtPA) is the only approved treatment for acute ischemic stroke (AIS) patients, however, only a minuscule percentage of patients receive rtPA [1, 2].

Obesity 40

Obesity Strokes Stroke Risk Factors 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP277-ATP277, February 1, 2024. Background:The Hispanic community in the US experiences disproportionate burdens of stroke risk. Family types could impact health outcomes as a mechanism of social support, urging examination of their impact on stroke-related risk factors. had obesity.

Obesity 40

Obesity Risk Factors Hypertension Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A13-A13, February 1, 2024. Elderly obese stroke survivors (> 65 years) having a recurrent acute ischemic stroke (AIS), with or without prior bariatric surgery (PBS), were identified using ICD-10 codes. Both groups (PBS vs. no PBS) were predominantly female (59.7% vs. 90.7%).

Obesity 40

Obesity Inpatient Strokes Stroke 40

Circulation

JANUARY 24, 2024

METHODS:The AHA, through its Epidemiology and Prevention Statistics Committee, continuously monitors and evaluates sources of data on heart disease and stroke in the United States and globally to provide the most current information available in the annual Statistical Update with review of published literature through the year before writing.

Heart Disease 81

Heart Disease Peripheral Arterial Disease Strokes Stroke 81

Cardiometabolic Health Congress

JULY 25, 2023

Can you please explain the concept of an obesity paradox? Salvatore Carbone, PhD: First, I’d like to point out that obesity is a major risk factor for cardiometabolic disease. 2, 3] This association is more pronounced for those with class I obesity, which is a body mass index (BMI) between 30-35 kg/m2.

Obesity 52

Obesity BMI Heart Failure Cardiovascular Disease 52

Dr. Paddy Barrett

FEBRUARY 14, 2025

low cholesterol), the total score can easily be taken to greater than 10 with other risk factors, including high blood pressure, obesity, inactivity, smoking etc. Overweight but not obese and a systolic blood pressure of 135 mmHg (Not very high but certainly not ideal). But even if your cholesterol score is very small (i.e.

Cholesterol 112

Cholesterol Heart Disease Heart attacks Heart Attack 112

Stroke Journal

JUNE 6, 2024

Stroke, Ahead of Print.

Obesity 40

Obesity Strokes Stroke 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP262-ATP262, February 1, 2024. Background:Obesity has been associated with an increase in the risk of stroke and poor outcomes. Meanwhile, Metabolically healthy obesity (MHO) trends are understudied in association with stroke. p<0.001) compared to the MHO+ve cohort.

Obesity 40

Obesity Hospital Strokes Stroke 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATMP100-ATMP100, February 1, 2024. Introduction:Rising obesity rates and the increasing prevalence of stroke in the metabolically healthy obese (MHO) necessitate examining its association in younger (18-44 year) populations.

Obesity 40

Obesity Strokes Stroke Outcomes 40

Circulation: Heart Failure

OCTOBER 27, 2023

The role of obesity in RV dysfunction and adverse outcomes is unclear.METHODS:We examined patients undergoing right heart catheterization between 2005 and 2016 in a hospital-based cohort. P<0.001), and lower RV stroke work index (β, −0.05; SE, 0.01;P<0.001). P<0.001). P<0.001). Over median of 7.3

Obesity 40

Obesity Outcomes Heart Failure Pulmonary 40

AMS Cardiology

MARCH 31, 2025

This condition can lead to various complications, including stroke and heart failure, making it essential to understand its causes, symptoms, and AFib treatment options. Obesity : Excess weight increases the risk of heart-related issues, including AFib. If a clot travels to the brain, it can result in a stroke.

Atrial Fibrillation 52

Atrial Fibrillation AFIB Heart Rhythm Blood Pressure 52

Journal of the American Heart Association

FEBRUARY 8, 2025

This analysis evaluated the efficacy and safety of bempedoic acid in people with obesity participating in the CLEAR (Cholesterol Lowering via Bempedoic Acid [ECT1002], an ACLInhibiting Regimen) Outcomes trial.MethodsCLEAR Outcomes randomized 13 970 patients to daily bempedoic acid 180 mg or placebo. and hsCRP of 23.2% at 6 months.

Obesity 40

Obesity Outcomes Cholesterol Myocardial Infarction 40

European Journal of Heart Failure

DECEMBER 7, 2023

Increasing severity of obesity is associated with multiple characteristics that may contribute to the development or worsening of heart failure (HF) with preserved ejection fraction (HFpEF). Echocardiography demonstrated increased CO with obesity, but not estimated right atrial (RA) pressure or E/e′. Overall, 60.9%

Preserved Ejection Fraction 40

Preserved Ejection Fraction Obesity Heart Failure BMI 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page A51-A51, February 1, 2025. Pooled analysis of primary and secondary endpoints showed that GLP-1 RAs significantly reduced the risk of incidence of stroke by 12% (OR, 0.88(95%CI: 0.96),P<0.001), and nonfatal stroke by 13% (OR, 0.87(95%CI: However, the risk of fatal stroke (OR, 0.94(95%CI:

Heart Failure 40

Heart Failure Obesity Strokes Stroke 40

Dr. Paddy Barrett

AUGUST 30, 2024

Obesity is one of the biggest global health concerns we face today. Obesity is also a key driver of risk for cardiovascular disease. Although there are many factors linked to obesity, one factor is certain: excess caloric intake leads to an excess in the energy balance. Obesity (Silver Spring). Lancet Healthy Longev.

Heart Disease 111

Heart Disease Dementia Obesity Heart Attack 111

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWMP106-AWMP106, February 1, 2025. Introduction:An elevated urinary albumin-to-creatinine ratio (UACR), a marker of renal dysfunction, has been linked to an increased incidence of stroke. Those with elevated UACR (top tertile) had a higher incidence of stroke (4.6% 1.66, p=0.011).

Strokes 40

Strokes Stroke Obesity Education 40

Cardiovascular Diabetology

JANUARY 12, 2024

Individuals who are overweight or obese often develop insulin resistance, mediation of the association between body mass index (BMI) and stroke risk through the triglyceride-glucose index (TyG) seems plausible.

BMI 52

BMI Obesity Strokes Stroke 52

Medical Xpress - Cardiology

NOVEMBER 5, 2024

Slightly overweight stroke survivors have a lower risk of sustaining disabilities. The Kobe University finding adds another aspect to the obesity paradox but also highlights the importance of considering the population's normal when recommending best practices.

BMI 40

BMI Best Practices Strokes Stroke 40

Open Heart

JUNE 9, 2023

Body mass index (BMI) ‘(weight (kg)/height (m) 2 ) was calculated and patients with BMI ≥30 kg/m 2 were categorised as obese. kg/m 2 and 23.2% (255) were categorised as obese. On multivariable analysis, obesity showed paradoxical protective effect with adjusted OR of 0.59 (95% CI 0.36 to 7.15, p=0.007).

Obesity 40

Obesity BMI Hospital Thrombosis 40

DAIC

JUNE 28, 2024

These projected trends are driven by an aging, more diverse population, along with an anticipated significant increase in chronic health risk factors including high blood pressure and obesity. “In A woman’s risk for heart disease and stroke changes over the course of her life.

Cardiovascular Disease 105

Cardiovascular Disease Obesity Research Heart Disease 105

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page A94-A94, February 1, 2025. Introduction:Ischemic stroke is a leading cause of death and disability worldwide, but there has been limited success in translating putative treatments from preclinical trials to patients. Imaging from 1766 mice was used in this study.

Strokes 40

Strokes Stroke Diet Outcomes 40

Frontiers in Cardiovascular Medicine

DECEMBER 5, 2024

The molecular mechanisms underlying the impaired effects of altered lipoproteins have been studied in numerous in vitro and in vivo studies, and have been extensively analyzed in coronary atherosclerosis, especially in the context of pathologies such as dyslipidemia, diabetes, obesity, and metabolic syndrome.

Circulation 40

Circulation Strokes Stroke Atherosclerosis 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP235-AWP235, February 1, 2024. Introduction:Amid the rising prevalence of cannabis use disorder (CUD) in older adults and with surveys reporting ~85% of overlapping use for medicinal and recreational purposes in American cannabis users, the link between CUD and stroke is paramount. vs. 28.4%).

Inpatient 45

Inpatient Strokes Stroke Obesity 45

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP268-ATP268, February 1, 2025. Introduction:Xylitol, a sugar alcohol with a global market estimated at 161,500 metric tons, has been linked to increased thrombosis and risk of stroke and heart attack.

Thrombosis 40

Thrombosis Obesity Strokes Stroke 40

Stroke Journal

DECEMBER 19, 2024

Stroke, Ahead of Print. The latest research on socioeconomic status (SES) and stroke continues to demonstrate that individuals with low SES are at a higher risk of stroke, receive lower-quality care, and experience poorer outcomes. Addressing stroke inequalities requires an interdisciplinary approach.

Strokes 40

Strokes Stroke Risk Factors Hypertension 40