Obesity-Related Heart Disease Deaths Rose Roughly 180% Since 1999
HCPLive
NOVEMBER 17, 2024
Obesity-related ischemic heart disease deaths rose from 1999 to 2020, particularly in middle-aged men and Black adults, per CDC WONDER data.
Obesity Related Topics 
Patients With Obesity Shed Pounds With Drug-Free Capsule
Med Page Today
NOVEMBER 8, 2024
(MedPage Today) -- SAN ANTONIO -- Use of an oral biodegradable drug-free capsule led to more weight loss among patients with overweight or obesity compared with placebo, according to the randomized RESET trial. Among 279 patients, mean change.
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Tirzepatide Officially Puts GLP-1 Meds on the Map for Obesity-Related Heart Failure
Med Page Today
NOVEMBER 16, 2024
(MedPage Today) -- CHICAGO -- A long-acting GIP/GLP-1 receptor agonist conferred significant clinical benefit for people with obesity and accompanying heart failure with preserved ejection fraction (HFpEF), according to the SUMMIT trial. Incident.
Tirzepatide lowered risk of worsening heart failure and CVD death for obese adults
American Heart News - Heart News
NOVEMBER 16, 2024
called SUMMIT, participants with heart failure with preserved ejection fraction (HFpEF) and obesity taking tirzepatide for an average of 2 years had. Research Highlights: In an international trial of 713 adults in nine countries including the U.S.
Modulation of NOX2 causes obesity-mediated atrial fibrillation
Journal of Clinical Investigation - Cardiology
SEPTEMBER 17, 2024
Obesity is linked to an increased risk of atrial fibrillation (AF) via increased oxidative stress. Here, we studied NOX2-mediated ROS production in obesity-mediated AF using Nox2-knockout mice and mature human induced pluripotent stem cell–derived atrial cardiomyocytes (hiPSC-aCMs).
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Obesity Linked to Elevated Gout Risk
HCPLive
AUGUST 7, 2024
Obesity was more prevalent among patients with gout and obesity indicators were significantly higher in this group.
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180% increase in obesity-related heart disease deaths: 8 notes
Becker's Hospital Review - Cardiology
NOVEMBER 13, 2024
Between 1999 and 2020, obesity-related deaths from heart disease deaths in the U.S. increased by 180%, according to a preliminary study to be presented at the American Heart Association's annual Scientific Sessions, set for Nov.
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Connections between obesity and heart failure
Science Daily - Heart Disease
AUGUST 1, 2024
A new small study has revealed the impact of obesity on muscle structure in patients having a form of heart failure called heart failure with a preserved ejection fraction (HFpEF).
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Significant gaps between science of obesity and the care patients receive
American Heart News - Heart News
MAY 20, 2024
Statement Highlights: More than 40% of adults in the United States live with obesity, and the percentage of people living with obesity continues to increase dramatically. While experts have learned a great deal about the causes of obesity and.
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Tirzepatide for Heart Failure with Preserved Ejection Fraction and Obesity
The New England Journal of Medicine
NOVEMBER 15, 2024
In patients with heart failure with preserved ejection fraction and obesity, treatment with tirzepatide led to a lower risk of death from cardiovascular causes or worsening heart-failure events than placebo.
MASLD Increases Risk of Youth-Onset Type 2 Diabetes in Children with Obesity
HCPLive
OCTOBER 15, 2024
Study findings showed children with both obesity and MASLD have a greater risk of youth-onset type 2 diabetes than those with obesity alone.
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ASN Releases New Guidance on Obesity Management in Kidney Disease
HCPLive
SEPTEMBER 18, 2024
The new guidance reviews existing tools for weight management and provides recommendations for their use in clinical practice in patients with obesity and kidney disease.
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SUMMIT: Tirzepatide Improves Outcomes and Quality of Life For Patients With HFpEF and Obesity
American College of Cardiology
NOVEMBER 16, 2024
In patients with obesity and heart failure with preserved ejection fraction (HFpEF), weekly treatment with tirzepatide over approximately two years reduced the risk of worsening heart failure events, based on findings from the SUMMIT trial.
Need 10,000 Daily Steps to Prevent Obesity? It May Depend on Genetics
Med Page Today
MARCH 27, 2024
(MedPage Today) -- The daily step count needed to reduce the risk of obesity may be largely dependent on genetics, a retrospective cohort study indicated. adults without obesity in the All of Us Research Program, incidence of obesity.
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Metabolic Accelerator Shows Promise for Weight Loss Side of Obesity-HFpEF Equation
Med Page Today
OCTOBER 2, 2024
(MedPage Today) -- The novel investigational weight loss agent HU6 had mixed results specifically targeting obesity-related heart failure with preserved ejection fraction (HFpEF), based on the small HuMain-HFpEF trial. After 19 weeks on daily.
Analysis found weight-loss surgery may help people with obesity manage high blood pressure
American Heart News - Heart News
SEPTEMBER 5, 2024
Research Highlights: In an analysis of 18 randomized clinical trials, people with obesity and high blood pressure who underwent bariatric (weight-loss) surgery were almost three times more likely to achieve blood pressure remission, defined as.
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Obesity-related heart disease deaths increased in the U.S. over the past two decades
American Heart News - Heart News
NOVEMBER 11, 2024
who died from ischemic heart disease related to obesity increased by approximately 180% from 1999 to 2020. American Heart Association Scientific Sessions 2024, Abstract AC.MDP.13 13 - An analysis of data from the CDC’s WONDER database found that the number of people in the U.S.
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Obesity Linked to Worse Patient-Reported Outcomes in Rheumatoid Arthritis
HCPLive
JUNE 29, 2024
Patients with RA and obesity exhibited worse scores for subjective measures like pain and fatigue compared to those without obesity.
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Popular Diabetes Drug Class Lowered Risk of 10 Obesity-Associated Cancers
Med Page Today
JULY 5, 2024
(MedPage Today) -- GLP-1 receptor agonists lowered the risk of several obesity-associated cancers, a retrospective analysis of electronic health records suggested. Compared with insulin, GLP-1s were associated with a lower risk for developing.
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116 Anti-Obesity Drugs, Lifestyle Interventions Show CV Benefits Beyond Weight Loss
American College of Cardiology
NOVEMBER 18, 2024
Popular anti-obesity drugs continue to show cardiovascular benefits beyond weight loss, according to new research published in JACC and simultaneously presented at AHA 2024.
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ObesityWeek Roundup: Patients More Likely to Ration Obesity Drugs
Med Page Today
NOVEMBER 11, 2024
(MedPage Today) -- SAN ANTONIO -- Research presented at the ObesityWeek annual meeting included studies on rationing of prescription medications among adults with obesity, weight loss results with 25 mg of oral semaglutide, and risk reduction.
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Have We Turned The Tide On Obesity?
Dr. Paddy Barrett
OCTOBER 11, 2024
Obesity is one of the world’s biggest health crisis and only seems to be getting worse. For over 50 years, the rates of obesity have continued to rise worldwide 1. The most recent data on obesity has shown a decline for the first time in a very long time. Between 2020 and 2023, the rates of obesity dropped by about 2% 2.
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Melanie Jay, MD: Advancing Equitable Approaches to Improve Obesity Care
HCPLive
APRIL 19, 2024
This interview segment featured a discussion on Jay’s ACP Internal Medicine Meeting presentation ‘Advancing Equitable Approaches to Improve Obesity Care.’
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Liraglutide Helped Cut BMI in Kids With Obesity as Young as 6
Med Page Today
SEPTEMBER 10, 2024
(MedPage Today) -- Liraglutide (Saxenda) added to lifestyle intervention helped reduce BMI in young children with obesity, the phase IIIa SCALE Kids trial found. By week 56, kids, ages 6 to <12 years, on once-daily 3-mg liraglutide lost 5.8.
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Central Obesity Potentially Linked to Hyperuricemia, Gout
HCPLive
JANUARY 25, 2024
After adjusting for confounders, data revealed higher levels of obesity indices were linked with a gradual and dose-dependent increase in urate levels.
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Tirzepatide Improves Sleep Apnea in Patients With Obesity, Drugmaker Says
Med Page Today
APRIL 18, 2024
(MedPage Today) -- Tirzepatide (Zepbound) injections reduced sleep apnea severity among patients with obesity, regardless of positive airway pressure (PAP) use, according to topline data from two phase III trials. In the SURMOUNT-OSA 1 study.
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Exploring Obesity and the Latest Advances in Weight Loss Drugs during Healthy Weight Week
Cardiometabolic Health Congress
JANUARY 3, 2024
In today’s society, the prevalence of obesity has become a significant concern. have obesity, and this rate has increased by more than 10 percentage points in the past two decades. Understanding the prevalence of obesity is crucial in comprehending why events like Healthy Weight Week are essential. of adults in the U.S.
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Obesity Associated With Renal Function Decline, Kidney Disease Risk
HCPLive
FEBRUARY 2, 2024
Obesity was linked to an increased risk of focal segmental glomerulosclerosis and hypertensive nephropathy, with further analysis revealing its impact on the risk of developing end-stage kidney disease.
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New weight loss medication may help lower blood pressure in adults with obesity
American Heart News - Heart News
FEBRUARY 5, 2024
Research Highlights: The weight loss medication tirzepatide significantly lowered the systolic blood pressure of nearly 500 adults who had obesity and took the medication for 36 weeks, or about eight months, in a subset of an international clinical.
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Childhood stress linked to higher risk of high blood pressure, obesity, diabetes in adults
American Heart News - Heart News
JANUARY 17, 2024
Research Highlights: Consistently high scores of perceived stress during adolescence through adulthood may contribute to worse cardiometabolic health including obesity in young adults. Researchers suggest the adoption of healthy coping strategies.
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JACC State-of-the-Art Review Explores Relationship Between Obesity and SCD
American College of Cardiology
NOVEMBER 20, 2024
Sudden cardiac death (SCD) in obesity is the focus of a JACC: State-of-the-Art review of the mechanisms as well as current evidence for its management, gaps in knowledge and future research, published in JACC.
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New Study Finds Tirzepatide Use Lowered Blood Pressure in Patients with Obesity
HCPLive
FEBRUARY 5, 2024
Tirzepatide, a dual GLP-1/GIP agonist approved for diabetes and obesity, was associated with significant blood pressure reductions in an analysis of the SURMOUNT-1 trial.
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ESC Consensus Statement on Obesity and CVD: Key Points
American College of Cardiology
SEPTEMBER 11, 2024
The following are key points to remember from a European Society of Cardiology (ESC) clinical consensus statement on obesity and cardiovascular disease (CVD).
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Abstract 4143390: HEMODYNAMIC AND CLINICAL IMPACT OF OBESITY IN GROUP 1 PULMONARY HYPERTENSION
Circulation
NOVEMBER 11, 2024
Clinical and hemodynamic implications of having obesity in group 1 PH remain unknown.Hypothesis. There was no difference in survival among patients with and without obesity (HR 1.15; 95% CI 0.95-1.38; Obese patients had higher RAP (12.8 ± 6.8 L/min, p< 0001) compared to non-obese group (Table 1). vs 10.4 ± 6.5
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Abstract 4125500: Obesity-Related Left Atrial Functional Change Becomes Apparent in Infancy
Circulation
NOVEMBER 11, 2024
Background:Impaired left atrial (LA) function is observed in obese patients, however, there is little information on when LA dysfunction begins to appear. To clarify this issue, we assessed LA volume and function in obese infants.Methods:Two-dimensional speckle-tracking echocardiography was performed in 96 infants aged 4 months.
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Obesity Linked to Increased Disease Activity in ACPA-Positive Rheumatoid Arthritis
HCPLive
FEBRUARY 14, 2024
Patients with ACPA-positive RA and obesity had greater DAS44 scores compared to normal-weight patients, although this difference was not present in ACPA-negative RA.
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Rivus HU6 Shows Obesity-HFpEF Potential
CardiacWire
AUGUST 14, 2024
Rivus Pharmaceuticals’ HU6 is showing promise as a future obesity-related HFpEF treatment, after topline results from its Phase 2a HuMAIN trial revealed valuable weight, symptom, and cardiometabolic improvements – without the risk of muscle loss. The post Rivus HU6 Shows Obesity-HFpEF Potential appeared first on Cardiac Wire.
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Emerging role of incretin-based therapy as first-line antihypertensives in obesity
Heart BMJ
SEPTEMBER 16, 2024
Obesity is a major global health issue and a leading cause of premature death. The prevalence of obesity has been rising faster than most other known modifiable risk factors. In a Global Burden of Disease analysis, the prevalence of obesity was found to have doubled in more than 70 countries from 1980 to 2013.
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Diabetes Dialogue: ADA Introduces Obesity Association, with Robert Gabbay, MD, PhD
HCPLive
JUNE 23, 2024
In the special on-site ADA 2024 episode, hosts are joined by the ADA's Chief Scientific and Medical Officer Robert Gabbay, MD, PhD, to discuss the newly formed Obesity Association.
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New study links obesity to elevated hypertension risk among young Middle Eastern women
Medical Xpress - Cardiology
OCTOBER 15, 2024
Obesity is a widespread public health challenge in the Middle East, maintaining prevalence in 54.2% Overweight and obese women have a higher risk of hypertension and cardiovascular risk factors than women with a standard BMI, according to an analysis of the ANCORS-YW STUDY presented at ACC Middle East 2024. of women and 31.4%
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Abstract 4144999: Cardiac Magnetic Resonance Imaging in Tetrology of Fallot Patients and Relationship to Obesity
Circulation
NOVEMBER 11, 2024
Obesity is associated with increased cardiovascular risk and adverse cardiac changes such as left ventricular hypertrophy (LVH) and in TOF higher body mass index (BMI) contributed to increase risk. In the presence of obesity, RVEDVi may underestimate the severity of RV volume load. mL/m2, p=0.04; RVEDVi 157.4±21.5 vs RVEDV 297.6±56.6
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Obesity cardiomyopathy could contribute to sudden cardiac death: a Japanese epidemiological morphological study
Cardiovascular Diabetology
OCTOBER 23, 2024
Background We aimed to clarify the existence and pathological features of obesity cardiomyopathy (OCM) in Japan using our series of autopsy cases. We compared cases of OCM with those with obesity without cardiac hypertrophy (OB) and normal weight without cardiac hypertrophy (normal control).
10-Year Follow-Up Shows Lasting Benefits of Bariatric Surgery for Teens with Severe Obesity
HCPLive
OCTOBER 30, 2024
A decade after bariatric surgery, most teens maintained weight loss and reduced obesity-related conditions such as type 2 diabetes and hypertension.
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Mitochondria- and NOX4-dependent antioxidant defense mitigates progression to nonalcoholic steatohepatitis in obesity
Journal of Clinical Investigation - Cardiology
FEBRUARY 1, 2024
Nonalcoholic fatty liver disease (NAFLD) is prevalent in the majority of individuals with obesity, but in a subset of these individuals, it progresses to nonalcoholic steatohepatitis (0NASH) and fibrosis. The mechanisms that prevent NASH and fibrosis in the majority of patients with NAFLD remain unclear.
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