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American College of Cardiology ACC.24 Late-breaking Science and Guidelines Session Summary

DAIC

24: Joint American College of Cardiology/Journal of the American College of Cardiology Late-Breaking Clinical Trials (Session 402) Saturday, April 6 9:30 – 10:30 a.m. ET Murphy Ballroom 4 ACC.24 24 planners note that attendees can gain insights from key clinical trials presented at ACC.24

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Association Between Polyvascular Disease and Transcatheter Aortic Valve Replacement Outcomes: Insights from the STS/ACC TVT Registry

Circulation: Cardiovascular Interventions

Background:Atherosclerotic cardiovascular disease (ASCVD) is highly prevalent in patients with severe aortic stenosis undergoing transcatheter aortic valve replacement (TAVR). Exposure of interest was PVD. Primary outcome was all-cause mortality.

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Diffuse Subendocardial Ischemia on the ECG. Left main? 3-vessel disease? No!

Dr. Smith's ECG Blog

A transthoracic echocardiogram showed an LV EF of less than 15%, critically severe aortic stenosis , severe LVH , and a small LV cavity. The aortic valve in this example also had critical stenosis by Doppler The patient continued to be hemodynamically unstable with poor cardiac output and very high LV filling pressures.

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Non-dual antiplatelet therapy versus dual antiplatelet therapy prior to transcatheter aortic valve replacement: A systematic review and meta-analysis

Journal of Cardiovascular Pharmacology

Abstract: Transcatheter aortic valve replacement (TAVR) is an interventional procedure performed in patients with severe aortic stenosis and often required perioperative antiplatelet therapy. Most previous studies have focused on antiplatelet therapy following TAVR. Copyright © 2023 Wolters Kluwer Health, Inc.

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Highlights of ACC 2024

Cardiology Update

EMPACT-MI 1 ( NCT04509674 ) studied the effects of empagliflozin in patients who have experienced myocardial infarction (MI). SMART 4 ( NCT04722250 ) studied patients with severe aortic stenosis and a small aortic annulus who underwent transcatheter aortic valve replacement (TAVR). vs. 6.2%) and stroke (2.9%

Angina 52
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Sex-specific aspects on prognosis after aortic valve replacement for aortic stenosis: a SWEDEHEART registry study

Open Heart

Objective To compare long-term cardiovascular (CV) outcomes between men and women with aortic stenosis (AS) undergoing aortic valve replacement (AVR) by the type of valve implant. In the TAVR cohort, men suffered a higher risk of death (HR: 1.24; 95% CI: 1.07 In the bioSAVR cohort, a higher risk of death (HR: 1.14; 95% CI: 1.04

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Published Research

Society of Thoracic Surgeons - Research

Adult Cardiac Surgery Database Lead Author Title Publication Date Jacob Raphael Red Blood Cell Transfusion and Pulmonary Complications: The Society of Thoracic Surgeons Adult Cardiac Surgery Database Analysis The Annals of Thoracic Surgery January 2024 Joseph Sabik Multi-Arterial versus Single-Arterial Coronary Surgery: Ten Year Follow-up of One Million (..)