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Pulse pressure and aortic valve peak velocity and incident heart failure after myocardial infarction: a cohort study

Heart BMJ

Background Heart failure with preserved ejection fraction is a recognised outcome in patients with myocardial infarction, although heart failure with reduced ejection fraction is more common. Among patients with myocardial infarction, a 1-SD increase in pulse pressure was associated with a 1.60-fold

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Pulse pressure and aortic valve peak velocity as new predictors of heart failure in patients post-myocardial infarction

Heart BMJ

Heart failure (HF) is one of the significant complications in patients with myocardial infarction (MI), leading to increased risk for cardiovascular morbidity and mortality. 2 However, mortality rate is greater in HF cases developing >3 days following MI compared with less than or equal to 3 days after MI.

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Beta‐blocker use and outcomes in patients with heart failure and mildly reduced and preserved ejection fraction

European Journal of Heart Failure

Beta-blockers are commonly used in patients with heart failure and mildly reduced or preserved ejection fraction (HFmrEF/HFpEF). Methods and results We pooled individual patient data from four large HFmrEF/HFpEF trials (I-Preserve, TOPCAT, PARAGON-HF, and DELIVER).

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Cardiorespiratory Fitness and Risk of Heart Failure with Preserved Ejection Fraction

European Journal of Heart Failure

Abstract Aims Preventive strategies for heart failure (HF) with preserved ejection fraction (HFpEF) include pharmacotherapies and lifestyle modifications. All had no evidence of HF or myocardial infarction prior to completion of the ETT. Thus, we evaluated the association between CRF and HFpEF incidence.

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Systematic review and meta-analysis of early aortic valve replacement versus conservative therapy in patients with asymptomatic aortic valve stenosis with preserved left ventricle systolic function

Open Heart

The secondary outcomes were composite major adverse cardiac events (MACE) (study defined), myocardial infarction (MI), stroke, cardiac death, sudden death, the development of symptoms, heart failure hospitalisations and major bleeding. The primary outcome was all-cause mortality. PROSPERO registration number CRD42022306132.

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Dapagliflozin and Apparent Treatment-Resistant Hypertension in Heart Failure With Mildly Reduced or Preserved Ejection Fraction: The DELIVER Trial

Circulation

BACKGROUND:Apparent treatment-resistant hypertension (aTRH) is prevalent and associated with adverse outcomes in heart failure with mildly reduced or preserved ejection fraction. Less is known about the potential role of sodium-glucose co-transporter 2 inhibition in this high-risk population. per 100 patient-years).

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Mineralocorticoid Receptor Antagonists in Heart Failure: An Update

Circulation: Heart Failure

Spironolactone improved outcomes in patients with severely symptomatic HF with reduced ejection fraction, and later, eplerenone expanded the benefits to patients with mildly symptomatic HF with reduced ejection fraction and myocardial infarction complicated by HF.