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Thus, it has recently become generally accepted that most plaque ruptures resulting in myocardialinfarction occur in plaques that narrow the lumen diameter by 40% of the arterial cross section may be involved by plaque. Fig 1 shows typical examples of two such plaques.
MINOCA may be due to: coronary spasm, coronary microvascular dysfunction, plaque disruption, spontaneous coronary thrombosis/emboli , and coronary dissection; myocardial disorders, including myocarditis, takotsubo cardiomyopathy, and other cardiomyopathies. MINOCA I do not have the bandwidth here to write a review of MINOCA.
Anaphylaxis leads to plaque rupture or erosion leading to acute myocardialinfarction (type II) and acute coronary stent thrombosis (type III). Here we share a case of Kounis syndrome type I caused by an allergy caused by a Cryptopteran bite.
To prove there is no plaque rupture, you need to do intravascular ultrasound (IVUS). An angiogram is a "lumenogram;" most plaque is EXTRALUMINAL!! Such cases are classified as MINOCA (MyocardialInfarction with Non-Obstructed Coronary Arteries). It can only be seen by IVUS. MINOCA has many etiologies. Learning Points: 1.
If the arrest was caused by acute MI due to plaque rupture, then the diagnosis is MINOCA. MINOCA: MyocardialInfarction in the Absence of Obstructive Coronary Artery Disease). Here is my comment on MINOCA: "Non-obstructive coronary disease" does not necessarily imply "no plaque rupture with thrombus." FFR can be useful.
Therefore it means acute type 1 ACS plaque rupture with impeded flow and impending full occlusion until proven otherwise. A New ST-segment elevation myocardialinfarction equivalent pattern? The reappearance of de Winter's pattern caused by acute stent thrombosis: A case report. Am J Emerg Med. 2014;32:e5–e8.
New insights into the use of the 12-lead electrocardiogram for diagnosing acute myocardialinfarction in the emergency department. Here is the abstract: Background Identification of ST elevation myocardialinfarction (STEMI) is critical because early reperfusion can save myocardium and increase survival.
The ECLIPSE trial shows that use of IVI to guide coronary stenting in severely calcified lesions prevents death, stent thrombosis, and unplanned repeat procedures in this high-risk patient population. The ECLIPSE trial results were presented at the American College of Cardiology Scientific Session (ACC.25)
Atherosclerotic cardiovascular disease (ASCVD), caused by plaque buildup in arterial walls, is one of the leading causes of disability and death worldwide.1,2 3 Patients with ASCVD are at a higher risk for major adverse cardiovascular events (MACE) including heart attack or myocardialinfarction (MI), stroke, and cardiovascular (CV) death.4
EMPACT-MI 1 ( NCT04509674 ) studied the effects of empagliflozin in patients who have experienced myocardialinfarction (MI). The primary non-inferiority endpoint was MACCE (a composite of cardiac death, MI, ischaemic stroke, stent thrombosis, or target vessel revascularisation). Here is our curated list of the top sessions.
Decedents with acute coronary thrombosis, myocardialinfarction, or other myocardial abnormality were excluded. Decedents with either noncardiac death or SAD had similar height, weight, and heart weight. Moreover, decedents with SAD had lower cardiomyocyte width (mean, 18.6 m versus 19.6 m; mean difference, 1.0
This was attributed to a "Type 2 MI", which is acute MI that is not due to ruptured plaque, but rather due to "supply demand oxygen mismatch". Most MINOCA is due to ruptured plaque with thrombus that lyses and does not leave behind a visible culprit. They made a final diagnosis of type II myocardialinfarction.
Angiography was technically challenging as the patient was receiving CPR, but the cardiologist suspected acute stent thrombosis and initiated cangrelor, although no repeat angiography was able to be obtained. Acute myocardialinfarction: an uncommon complication of takotsubo cardiomyopathy. SanzRuiz, R., Solis, J., &
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