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Vessel-Level Coronary Atherosclerotic Plaque Activity Predicts Myocardial Infarction Risk

Cardiology Update

Recent research has illuminated the role of total coronary atherosclerotic plaque activity across the entire coronary arterial tree in predicting patient-level clinical outcomes. Vessel-level coronary atherosclerotic plaque activity was assessed using coronary 18 F-sodium fluoride positron emission tomography (PET). 3.72; P = 0.013).

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Coronary Atherosclerotic Plaque Activity and Risk of MI

American College of Cardiology

Is vessel-level coronary atherosclerotic plaque activity using coronary 18F-sodium fluoride positron emission tomography (PET) associated with patient vessel-level myocardial infarction (MI)?

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Effects of the PCSK9 Antibody Alirocumab on Coronary Atherosclerosis in Patients With Acute Myocardial Infarction

American College of Cardiology

The goal of the PACMAN-AMI trial was to demonstrate the efficacy of early administration of alirocumab on plaque characteristics among patients undergoing percutaneous coronary intervention (PCI) for an acute myocardial infarction (AMI).

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Microplastics, Nanoplastics, and Major Cardiac Events

CardiacWire

A landmark NEJM study revealed that many patients with carotid artery disease might have microplastics and nanoplastics (MNPs) embedded in their carotid plaque, and those patients have a massive 4.5-fold of patients had polyethylene in their plaque and 12.1% in patients without MNPs in their plaque. An alarming 58.4%

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Dynamic OMI ECG. Negative trops and negative angiogram does not rule out coronary ischemia or ACS.

Dr. Smith's ECG Blog

Thus, it has recently become generally accepted that most plaque ruptures resulting in myocardial infarction occur in plaques that narrow the lumen diameter by 40% of the arterial cross section may be involved by plaque. Fig 1 shows typical examples of two such plaques.

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Unveiling the role of long non-coding RNA MALAT1: a comprehensive review on myocardial infarction

Frontiers in Cardiovascular Medicine

Myocardial infarction (MI) stands at top global causes of death in developed countries, owing mostly to atherosclerotic plaque growth and endothelial injury-induced reduction in coronary blood flow. While early reperfusion techniques have improved outcomes, long-term treatment continues to be difficult.

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Prehospital triage in suspected myocardial infarction: a calculated risk?

Heart BMJ

For life-threatening events involving complete occlusion of a coronary artery, the activation of ST-elevation myocardial infarction protocols instructs the emergency services to provide immediate treatment and liaise directly with cardiac centres regarding invasive management, in turn, reducing morbidity and saving lives. 1 In this.