Heart BMJ

JANUARY 10, 2024

Myocardial infarction with non-obstructive coronary arteries (MINOCA) defines a heterogeneous group of atherosclerotic and non-atherosclerotic conditions, causing myocardial injury in the absence of obstructive coronary artery disease.

Myocardial Infarction 40

Myocardial Infarction Coronary Artery Disease Ultrasound Plaque 40

Frontiers in Cardiovascular Medicine

FEBRUARY 8, 2024

Objective Assessing the impact of lumbar disc herniation (LDH) on the plaque burden of coronary atherosclerosis is our objective. Gensini scores were calculated to assess the plaque burden of coronary. The association between lumbar disc lesions grading and coronary plaque burden was analysed by Spearman's correlation test.

Plaque 59

Plaque Angina Myocardial Infarction Risk Factors 59

Stroke Journal

DECEMBER 8, 2023

BACKGROUND:Aortic arch plaques are associated with an increased risk of ischemic stroke in patients with cryptogenic stroke or prior embolic events. Arch plaques were assessed by suprasternal transthoracic echocardiography; plaques ≥4 mm in thickness were classified as large plaques. Stroke, Ahead of Print.

Plaque 40

Plaque Aortic Stroke Strokes 40

CardiacWire

MARCH 8, 2024

A landmark NEJM study revealed that many patients with carotid artery disease might have microplastics and nanoplastics (MNPs) embedded in their carotid plaque, and those patients have a massive 4.5-fold of patients had polyethylene in their plaque and 12.1% in patients without MNPs in their plaque. An alarming 58.4%

Plaque 119

Plaque Myocardial Infarction Heart Attack Heart attacks 119

DAIC

JULY 18, 2024

This registry will aim to provide world-wide physicians the most accurate information on coronary plaque to improve cardiovascular risk prediction and support the selection of patient-specific treatment,” said Dr. De Cecco. The ultimate goal is to positively impact cardiovascular health globally with a reduction in cardiovascular events."

Plaque 105

Plaque Heart Attack Heart attacks Cardiovascular Disease 105

NEJM Journal Watch - Cardiology

APRIL 11, 2024

However, many of the events prevented were subsequent PCIs, so future studies focused on death and myocardial infarction outcomes are needed.

Myocardial Infarction 40

Myocardial Infarction Plaque Outcomes 40

Frontiers in Cardiovascular Medicine

JUNE 26, 2024

ACS may arise from the disruption of an atherosclerotic plaque, ultimately leading to acute ischemia and myocardial infarction. Colchicine exerts anti-inflammatory properties affecting both the myocardium and atherosclerotic plaque by modulating the activity of monocyte/macrophages, neutrophils, and platelets.

Plaque 52

Plaque Myocardial Infarction Atherosclerosis Heart Failure 52

The British Journal of Cardiology

AUGUST 1, 2024

Elevated Lp(a) concentrations in patients with ischaemic heart disease have been linked to higher rates of peri-procedural myocardial infarction (MI) during percutaneous coronary intervention (PCI). This review summarises the available data on the modulatory effect of Lp(a) on plaque morphology and recurrent ischaemic events.

Peripheral Arterial Disease 52

Peripheral Arterial Disease Myocardial Infarction Plaque Cardiovascular Disease 52

Frontiers in Cardiovascular Medicine

FEBRUARY 20, 2024

We investigated whether treatment with LDE-paclitaxel changes plaque progression by coronary CT angiography and is safe in patients with chronic coronary artery disease. Among those, 58% had diabetes, 50% had myocardial infarction, and 91% were in use of statin and aspirin.

Coronary Artery Disease 59

Coronary Artery Disease Laboratory Plaque Biomarkers 59

Dr. Paddy Barrett

JANUARY 30, 2024

The CAC scan looks for deposits of calcium in the areas of the coronary arteries as a proxy marker for plaque. It tells you ‘ if ’ there is plaque and how much, as a score called a CAC score. MI = Myocardial Infarction/Heart Attack However, there are two very important caveats. Int J Cardiol.

Heart Disease 70

Heart Disease Heart Attack Heart attacks Plaque 70

Frontiers in Cardiovascular Medicine

FEBRUARY 5, 2024

Anaphylaxis leads to plaque rupture or erosion leading to acute myocardial infarction (type II) and acute coronary stent thrombosis (type III). Here we share a case of Kounis syndrome type I caused by an allergy caused by a Cryptopteran bite.

Coronary Artery Disease 64

Coronary Artery Disease Electrocardiogram Myocardial Infarction Thrombosis 64

All About Cardiovascular System and Disorders

MARCH 7, 2024

Detailed analysis of the excised carotid plaques were carried out with pyrolysis-gas chromatography-mass spectrometry, stable isotope analysis, and electron microscopy. Primary endpoint of the study was a composite of myocardial infarction, stroke, or death from any cause in those who had micro and nanoplastics in the carotid plaque.

Plaque 52

Plaque Myocardial Infarction Laboratory Cardiac Function 52

Dr. Smith's ECG Blog

NOVEMBER 15, 2023

MINOCA may be due to: coronary spasm, coronary microvascular dysfunction, plaque disruption, spontaneous coronary thrombosis/emboli , and coronary dissection; myocardial disorders, including myocarditis, takotsubo cardiomyopathy, and other cardiomyopathies. MINOCA I do not have the bandwidth here to write a review of MINOCA.

Coronary Angiogram 100

Coronary Angiogram Plaque Thrombosis STEMI 100

All About Cardiovascular System and Disorders

APRIL 30, 2024

Plaque regression can be demonstrated by ultrasound evaluation of the carotids which are easily accessible. Maintaining normal blood pressure also reduces the risk of stroke and myocardial infarction. Of course, exercise burns out extra calories and reduces body weight, which in turn is due to a decrease in the fat deposits.

Exercise 52

Exercise Heart Disease Blood Pressure Cholesterol 52

DAIC

MAY 8, 2024

It provides anatomic data, plaque identification and characterization, as well as the calculations of FFR CT , a coronary physiological simulation, computed from simulated pressure, velocity and blood flow information obtained from a 3D computer model generated from static coronary CT images.

Coronary Artery Disease 111

Coronary Artery Disease Chest Pain Myocardial Infarction Ischemia 111

Stroke Journal

NOVEMBER 9, 2023

This article describes the pathway from gene discovery to novel therapeutic approaches that are now entering man.HDAC9expression is elevated in human atherosclerotic plaque, while in animal and cellular models, reducing HDAC9 (histone deacetylase 9) protein is associated with reduced disease.

Stroke 40

Stroke Strokes Atherosclerosis Coronary Artery Disease 40

DAIC

FEBRUARY 29, 2024

ET Main Tent (Hall B1) - A Double-blind, Randomized Placebo Procedure-controlled Trial of an Interatrial Shunt in Patients with HFrEF and HFpEF: Principal Results From the RELIEVE-HF Trial - Empagliflozin After Acute Myocardial Infarction: Results of the EMPACT-MI Trial - CSL112 (Apolipoprotein A-I) Infusions and Cardiovascular Outcomes in Patients (..)

Aortic valve 103

Aortic valve Myocardial Infarction Aortic Blood Pressure 103

Dr. Paddy Barrett

AUGUST 1, 2023

A CTCA provides much more anatomical detail and can identify advanced plaque often missed by CT Coronary Artery Calcium Score scans alone. There are 3 types of coronary atherosclerosis visible on CTCA: Calcified Plaque - Easily Identified on both CT CAC & CTCA scans. Subscribe now How Often Does A CT CAC Scan Miss Plaque?

Coronary Angiogram 52

Coronary Angiogram Plaque Coronary Artery Disease Chest Pain 52

Dr. Smith's ECG Blog

APRIL 22, 2024

A comparison of electrocardiographic changes during reperfusion of acute myocardial infarction by thrombolysis or percutaneous transluminal coronary angioplasty. Electrocardiographic diagnosis of reperfusion during thrombolytic therapy in acute myocardial infarction. Am Heart J. 2000;139:430–436. Am J Cardiol.

Chest Pain 118

Chest Pain Myocardial Infarction Anatomy Angina 118

Dr. Paddy Barrett

APRIL 5, 2024

2 Trends and Predictors of Participation in Cardiac Rehabilitation Following Acute Myocardial Infarction: Data From the Behavioral Risk Factor Surveillance System. 7 Secondary prevention following myocardial infarction: a clinical update. 11 Efficacy and Safety of Low-Dose Colchicine after Myocardial Infarction.

Heart Disease 98

Heart Disease Coronary Artery Disease Heart Attack Heart attacks 98

Cardiometabolic Health Congress

JUNE 20, 2024

Giovanna Liuzzo (Italy) revealed that advancements in noninvasive imaging recently allow for direct visualization of coronary atherosclerotic plaques. Here are some notable highlights: Prof. This has major potential to refine risk stratification and enhance patient management. In contrast, Dr. Michael D.

Atherosclerosis 59

Atherosclerosis Cardiovascular Disease Coronary Artery Disease Myocardial Infarction 59

Circulation

NOVEMBER 8, 2023

Permanent coronary ligation was performed to establish myocardial infarction (MI). Compared with animals without PCOS, PCOS animals showed significantly exacerbated atherosclerotic plaque development and post-MI cardiac remodeling.

Coronary Artery Disease 40

Coronary Artery Disease Myocardial Infarction Circulation Plaque 40

DAIC

APRIL 7, 2024

As with elevated LDL-cholesterol, high levels of triglycerides and the lipid particles on which they are carried in the blood can contribute to the formation of “plaques” in the arteries that impede blood flow and can lead to heart attacks and strokes. Triglycerides store unused calories and provide energy to the body.

Cholesterol 116

Cholesterol Heart Attack Heart attacks Myocardial Infarction 116

DAIC

JANUARY 25, 2024

Among patients who had no plaque and zero calcium at time of CCTA, those with the most abnormal CaRi-Heart test results experienced 11-fold higher risk for cardiac mortality and 5-fold higher risk for major adverse cardiac events (MACE) than those who had normal CaRi-Heart test results. In June 2023, the U.S.

Heart Attack 110

Heart Attack Heart attacks Cardiovascular Disease Technology 110

Dr. Smith's ECG Blog

JANUARY 5, 2024

So there is probability of myocardial injury here (and because it is in the correct clinical setting, then myocardial infarction.) Although it is statistically unlikely, multiple plaque ruptures are possible. The PDA plaque was also bulky, but was not described as inflamed or ulcerated. Heitner et al.

Angina 106

Angina Plaque Document Stents 106

Dr. Smith's ECG Blog

MAY 19, 2020

If the arrest was caused by acute MI due to plaque rupture, then the diagnosis is MINOCA. MINOCA: Myocardial Infarction in the Absence of Obstructive Coronary Artery Disease). Here is my comment on MINOCA: "Non-obstructive coronary disease" does not necessarily imply "no plaque rupture with thrombus." FFR can be useful.

Defibrillator 52

Defibrillator Circulation Plaque Cardiac Arrest 52

Dr. Smith's ECG Blog

MAY 20, 2024

The scan also showed “scattered coronary artery plaques”. __ Smith comment 1 : the appropriate management at this point is to lower the blood pressure (lower afterload, which increases myocardial oxygen demand). Smith comment : Is the ACS (rupture plaque) with occlusion that is now reperfusing? Murakami MM.

Chest Pain 124

Chest Pain Blood Pressure Ischemia STEMI 124

DAIC

JANUARY 23, 2024

Atherosclerotic cardiovascular disease (ASCVD), caused by plaque buildup in arterial walls, is one of the leading causes of disability and death worldwide.1,2 3 Patients with ASCVD are at a higher risk for major adverse cardiovascular events (MACE) including heart attack or myocardial infarction (MI), stroke, and cardiovascular (CV) death.4

Cardiovascular Disease 111

Cardiovascular Disease Heart Attack Heart attacks Coronary Artery Disease 111

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

However, CTA head and neck 4 days later demonstrated 90 percent stenosis of the mid left V2 at the C3‐4 level and a 75‐90 percent stenosis of the left mid V2 segment at the C5‐6 level (hard and soft plaque in these areas). He was switched from DAPT to aspirin and warfarin because he was considered a “DAPT failure.”

Stenosis 40

Stenosis Peripheral Arterial Disease Atherosclerosis Pacemaker 40

Dr. Smith's ECG Blog

MARCH 17, 2024

Answer: This is MINOCA -- Myocardial Infarction with Non-Obstructive Coronary Arteries. Possible etiologies (depending on your definition) include: plaque rupture with spontaneous recanalization, coronary artery vasospasm, spontaneous coronary artery dissection, or other rarer causes. The name is self-explanatory.

Angina 74

Angina Chest Pain Ischemia Blog 74

Dr. Smith's ECG Blog

NOVEMBER 3, 2023

Therefore it means acute type 1 ACS plaque rupture with impeded flow and impending full occlusion until proven otherwise. A New ST-segment elevation myocardial infarction equivalent pattern? Association between opioid analgesia and delays to cardiac catheterization of patients with occlusion Myocardial Infarctions.

Chest Pain 86

Chest Pain Cardiogenic Shock Ischemia Myocardial Infarction 86

Dr. Sanjay Gupta

DECEMBER 19, 2022

The term MINOCA stands for Myocardial infarction with non-obstructive coronary arteries. She had some very minor plaque but certainly nothing that could explain the heart attack and therefore she was discharged with a diagnosis of MINOCA i.e I’ll try and explain this a bit better by using a case study.

Heart Attack 40

Heart Attack Heart attacks Blood Clot Chest Pain 40

Dr. Malcolm Kendrick

AUGUST 26, 2022

There are numerous other conditions leading to this kind of damage, which can trigger thrombus formation, causing strokes and myocardial infarctions. The thrombogenic hypothesis, that endothelial damage and subsequent clot formation underlies the formation and growth of plaques, may represent a better model for ASCVD.

Cardiovascular Disease 40

Cardiovascular Disease Cholesterol Article Plaque 40

Dr. Smith's ECG Blog

OCTOBER 24, 2018

This was diagnosed by IVUS (intravascular ultrasound) as a ruptured plaque. Therefore, this does not meet the definition of myocardial infarction ( 4th Universal Definition of MI ), which requires at least one troponin above the 99% reference range. As there was ruptured plaque, this is NOT Prinzmetal's angina.

STEMI 52

STEMI Angina Myocardial Infarction Plaque 52

EMS 12-Lead

JUNE 1, 2022

Detailed Considerations LBBB and Myocardial Infarction In the emergent setting it’s important to assess LBBB through the lens of the Smith-modified Sgarbossa criteria, especially in a context that is clinically consistent with Acute Coronary Syndrome. He received a permanent pacemaker during the subsequent inpatient stay. 4] Dodd, K.

Heart Failure 52

Heart Failure Myocardial Infarction Bradycardia Cardiomyopathy 52

Dr. Smith's ECG Blog

JULY 11, 2024

Case A 43 year old male with a history of DM II, hyperlipidemia, and a family history of myocardial infarction presented to a family clinic with two days of epigastric pain that started after consuming a meal. Because: 1) He has been reading this blog for a long time. 2) He is curious This is how Pendell got started.

Outcomes 92

Outcomes Stenosis Outpatient Echocardiogram 92

Cardiology Update

APRIL 9, 2024

EMPACT-MI 1 ( NCT04509674 ) studied the effects of empagliflozin in patients who have experienced myocardial infarction (MI). The PREVENT 12 ( NCT02316886 ) trial aimed to determine if performing preventive PCI on non-flow-limiting vulnerable plaques yields better clinical outcomes compared to relying solely on optimal medical therapy.

Angina 52

Angina Myocardial Infarction Aortic valve Coronary Artery Disease 52