Dr. Smith's ECG Blog

DECEMBER 11, 2023

Occlusion myocardial infarction is a clinical diagnosis Written by Willy Frick (@Willyhfrick). St depression in lead AVL differentiates inferior st-elevation myocardial infarction from pericarditis. link] Opiates are associated with worse outcomes in Myocardial Infarction. Circulation , 130 (25).

Myocardial Infarction 123

Myocardial Infarction Chest Pain STEMI Blood Pressure 123

Open Heart

FEBRUARY 17, 2025

Background Despite limited beneficial evidence, mechanical circulatory support (MCS) is commonly used in patients with acute myocardial infarction-related cardiogenic shock (AMI-CS). In this Dutch registry, we investigated MCS usage, associated patient characteristics and clinical outcomes.

Cardiogenic Shock 52

Cardiogenic Shock Myocardial Infarction Aortic Outcomes 52

Frontiers in Cardiovascular Medicine

FEBRUARY 24, 2025

IntroductionAcute coronary syndrome refers to a group of diseases characterized by sudden, decreased blood supply to the heart muscle that results in cell death, also known as acute myocardial infarction. The majority of patients (67.9%) have been diagnosed with ST- Elevated Myocardial Infarction and were classified as Killip class I.

Hospital 98

Hospital Myocardial Infarction Chest Pain Electrocardiogram 98

Open Heart

MARCH 28, 2025

The primary outcomes of interest were mortality in ventricular and atrial arrhythmias, and later diagnosis of cardiac disease in atrial arrhythmias. However, it is linked to subsequent diagnosis of AF, coronary artery disease and myocardial infarction.

Arrhythmia 64

Arrhythmia Coronary Artery Disease Myocardial Infarction Atrial Fibrillation 64

Open Heart

JANUARY 17, 2024

Objective In the COVERT-MI randomised placebo-controlled trial, oral administration of high-dose colchicine at the time of reperfusion and for 5 days in acute ST-elevated myocardial infarction did not reduce infarct size but was associated with a significant increase in left ventricular thrombus (LVT) in comparison to placebo.

Myocardial Infarction 96

Myocardial Infarction Quality of Life Heart Failure Arrhythmia 96

Nature Reviews - Cardiology

MAY 2, 2024

Nature Reviews Cardiology, Published online: 03 May 2024; doi:10.1038/s41569-024-01031-z In the AEGIS-II trial, infusion of apolipoprotein A-I to increase cholesterol efflux capacity did not improve outcomes in patients with acute myocardial infarction.

Myocardial Infarction 64

Myocardial Infarction Cholesterol Outcomes 64

European Journal of Heart Failure

FEBRUARY 16, 2025

Organ perfusion pressure as a predictor of outcomes in cardiogenic shock: insights from the Altshock-2 registry. This study evaluated organ perfusion pressure (OPP), calculated as mean arterial pressure minus invasive central venous pressure, as a predictor of outcomes in CS. The primary outcome was in-hospital all-cause mortality.

Cardiogenic Shock 40

Cardiogenic Shock Outcomes Myocardial Infarction Heart Failure 40

Frontiers in Cardiovascular Medicine

MARCH 28, 2025

ST-elevation myocardial infarction (STEMI) is a critical cardiovascular emergency characterized by acute coronary artery occlusion and subsequent myocardial injury. However, despite successful revascularization, microvascular obstruction (MVO) remains a major challenge, contributing to adverse clinical outcomes.

Thrombolysis 52

Thrombolysis STEMI Myocardial Infarction Article 52

Medical Xpress - Cardiology

OCTOBER 30, 2024

The largest trial to examine the impact of colchicine in acute myocardial infarction (MI) found that both acute and long-term colchicine use did not reduce cardiovascular death, myocardial infarction, stroke, or ischemia-driven revascularization.

Myocardial Infarction 52

Myocardial Infarction Ischemia Outcomes Stroke 52

Frontiers in Cardiovascular Medicine

MARCH 27, 2025

Observational studies and randomised controlled trials (RCTs) have yielded conflicting results regarding the outcomes of multiple arterial grafts (MAG) vs. single arterial grafts (SAG) in coronary artery bypass graft (CABG) surgery. We conducted a comprehensive search across multiple databases for RCTs that directly compared MAG and SAG.

Coronary Artery Bypass Graft 52

Coronary Artery Bypass Graft Myocardial Infarction Stroke Strokes 52

Journal of the American Heart Association

MARCH 7, 2025

The primary outcome was device success and allcause death, while secondary outcomes included myocardial infarction, stroke, and heart failure hospitalization rates at 30day and intermediateterm followup. Studies with <5 patients were excluded. A fixedeffects metaanalysis was used to estimate pooled rates.

Cardiogenic Shock 45

Cardiogenic Shock Bicuspid/Mitral Myocardial Infarction Heart Failure 45

Cardiology Update

FEBRUARY 11, 2024

The NOTION trial, a pioneering study, sought to compare the long-term clinical and bioprosthesis outcomes of Transcatheter Aortic Valve Implantation (TAVI) versus Surgical Aortic Valve Replacement (SAVR) in patients with severe aortic valve stenosis (AS) at lower surgical risk. Severe SVD was defined by specific criteria.

Aortic valve 124

Aortic valve Aortic Outcomes Thrombosis 124

Frontiers in Cardiovascular Medicine

DECEMBER 18, 2023

Objectives There is no consensus regarding the optimal choice between single long stent (SLS) and overlapped double short stents (DSS) in patients with acute myocardial infarction (AMI). Therefore, we aimed to compare treatment outcomes among patients with AMI treated with these two different stenting methods. years, and 75.0%

Stents 64

Stents Stent Myocardial Infarction Outcomes 64

Open Heart

MARCH 28, 2025

Background High-sensitivity cardiac troponin tests have enhanced early myocardial infarction diagnosis, yet many patients still land in the observe zone (OZ). The prevalence of non-ST-segment elevation myocardial infarction (NSTEMI) within the OZ was 7.2%. Results Of the 4605 patients, 948 were triaged to the OZ (20.6%).

Myocardial Infarction 52

Myocardial Infarction Outcomes 52

Cardiology Update

MARCH 25, 2024

Left main coronary artery disease (CAD) and diabetes pose significant challenges in cardiovascular care, often leading to adverse outcomes. Preliminary evidence from trials focusing on patients with multivessel disease has hinted at diabetes as a potential modifier of treatment outcomes. Original article: Gaba P et al. Circulation.

Diabetes 122

Diabetes Coronary Artery Bypass Graft Outcomes Coronary Artery Disease 122

Cardiovascular Diabetology

JULY 10, 2024

Background The effect of empagliflozin, a sodium-glucose-co-transporter-2 inhibitor, on risk for myocardial infarction has not been fully characterized.

Myocardial Infarction 52

Myocardial Infarction Coronary Artery Bypass Graft Outcomes Plaque 52

Journal of the American Heart Association

FEBRUARY 28, 2024

We assessed the association of cannabis use (number of days of cannabis use in the past 30 days) with self‐reported cardiovascular outcomes (coronary heart disease, myocardial infarction, stroke, and a composite measure of all 3) in multivariable regression models, adjusting for tobacco use and other characteristics in adults 18 to 74 years old.

Myocardial Infarction 76

Myocardial Infarction Outcomes Heart Disease Stroke 76

Frontiers in Cardiovascular Medicine

MARCH 10, 2024

Background Hyperglycemia, characterized by elevated blood glucose levels, is frequently observed in patients with acute coronary syndrome, including ST-elevation myocardial infarction (STEMI). There are conflicting sources regarding the relationship between hyperglycemia and outcomes in STEMI patients. 3.45) and 4.47 (95% CI: 2.54–7.87),

Myocardial Infarction 59

Myocardial Infarction Cardiogenic Shock Article STEMI 59

Med Page Today

NOVEMBER 17, 2024

(MedPage Today) -- CHICAGO -- A mineralocorticoid receptor antagonist (MRA) was unable to further improve 3-year outcomes of acute myocardial infarction (MI) in the modern era, based on the CLEAR OASIS 9 trial. Among heart attack survivors without.

Myocardial Infarction 105

Myocardial Infarction Heart Attack Heart attacks Outcomes 105

Journal of the American Heart Association

MARCH 27, 2025

BackgroundRecent evidence highlights an increasing incidence of myocardial infarction in young women. The primary outcome was a composite of inhospital adverse events. Associations between multimorbidity patterns and outcomes were evaluated using multivariableadjusted logistic regression models.

Myocardial Infarction 40

Myocardial Infarction Peripheral Arterial Disease Outcomes Chest Pain 40

Frontiers in Cardiovascular Medicine

JANUARY 3, 2024

Background Microcirculatory dysfunction is an independent risk factor for a poor prognosis after percutaneous coronary intervention (PCI) in patients with acute myocardial infarction (AMI). However, its effects on microcirculation in patients with AMI after primary PCI remain unknown.

Myocardial Infarction 59

Myocardial Infarction Outcomes Cardiac Function Thrombolysis 59

Frontiers in Cardiovascular Medicine

JANUARY 14, 2024

Background The objective of this study was to investigate the differences in presenting symptoms between patients with and without diabetes being diagnosed with an acute myocardial infarction (AMI). Methods A total of 5,900 patients with a first-time AMI were included into the analysis.

Myocardial Infarction 64

Myocardial Infarction Diabetes Chest Pain Risk Factors 64

Frontiers in Cardiovascular Medicine

MARCH 25, 2025

Cardio-cerebral infarction (CCI) is a rare clinical syndrome characterized by the simultaneous or sequential occurrence of acute myocardial infarction (AMI) and acute ischemic stroke (AIS). Consequently, clinicians often rely on single-disease guidelines for AMI or AIS, or personal experience, when managing CCI cases.

Myocardial Infarction 52

Myocardial Infarction Article Research Patient Care 52

Open Heart

MARCH 3, 2025

We aimed to compare outcomes between a broad range of second-generation DP-DES and BP-DES in an all-comer population. Conclusion Clinical follow-up up to 2 years shows similar outcomes between BP-DES and DP-DES. To date, no study has shown the superiority of one type of polymer compared with the other.

Stents 52

Stents Stent Myocardial Infarction Angioplasty 52

Med Page Today

APRIL 8, 2024

(MedPage Today) -- ATLANTA -- Chelation to remove lead and other heavy metals didn't improve outcomes for type 2 diabetes patients after myocardial infarction (MI), the TACT2 trial showed. Cumulative incidence of time to first event (MI, stroke.

Heart attacks 97

Heart attacks Heart Attack Myocardial Infarction Diabetes 97

American College of Cardiology

DECEMBER 2, 2024

Current guidelines regarding beta-blocker use after myocardial infarction (MI) recommend against continuation to improve outcomes after 1 year, in the absence of reduced left ventricular ejection fraction (LVEF; <50%) or other primary indications for therapy.

Myocardial Infarction 44

Myocardial Infarction Outcomes Article 44

Open Heart

JANUARY 11, 2024

This study aimed to investigate the association between the use of GTN before percutaneous coronary intervention (PCI) for ACS and clinical outcomes. Conclusions GTN use preceding PCI for ACS is associated with lower blood pressure and adverse clinical outcomes in elderly patients. –143.5) mm Hg vs 134.0 –157.0)

Blood Pressure 98

Blood Pressure Outcomes Myocardial Infarction Heart Failure 98

Frontiers in Cardiovascular Medicine

JANUARY 13, 2025

BackgroundThe pharmacoinvasive (PhI) strategy is the standard-of-care for ST-elevation myocardial infarction (STEMI) patients when primary percutaneous coronary intervention (pPCI) is unfeasible. Multivariable logistic regression models were used to assess the association between lysis-PCI timing and outcomes.

Myocardial Infarction 52

Myocardial Infarction Outcomes STEMI Hospital 52

Journal of the American Heart Association

DECEMBER 24, 2024

The primary outcome was atherothrombotic major adverse cardiovascular events as a composite outcome of cardiovascular mortality, nonfatal stroke, and nonfatal myocardial infarction. Patients were propensity matched in a 1:1 ratio using a caliper distance of 0.2 without replacement.

Diabetes 75

Diabetes Myocardial Infarction Outcomes Stroke 75

Journal of the American Heart Association

MARCH 26, 2025

The primary outcome was inhospital allcause mortality. Multivariable logistic regression models were used to estimate BMIstratified associations between SMuRFless status and outcomes.ResultsThe study included 44 538 patients with firstpresentation acute myocardial infarction, of whom 4454 were SMuRFless.

Myocardial Infarction 40

Myocardial Infarction Risk Factors BMI Obesity 40

Med Page Today

APRIL 10, 2024

(MedPage Today) -- ATLANTA -- Fractional flow reserve (FFR)-guided complete revascularization in patients with ST-segment elevation myocardial infarction (STEMI) and multivessel coronary artery disease did not result in better outcomes compared.

Coronary Artery Disease 64

Coronary Artery Disease Myocardial Infarction Outcomes STEMI 64

Frontiers in Cardiovascular Medicine

AUGUST 6, 2024

Myocardial infarction (MI) stands at top global causes of death in developed countries, owing mostly to atherosclerotic plaque growth and endothelial injury-induced reduction in coronary blood flow. While early reperfusion techniques have improved outcomes, long-term treatment continues to be difficult.

Myocardial Infarction 52

Myocardial Infarction Plaque Physiology Cardiovascular Disease 52

Cardiometabolic Health Congress

JANUARY 15, 2025

The Hidden Threat: SMuRFless Myocardial Infarctions A concerning trend in CVD is the increase in myocardial infarctions (MI) among individuals without standard modifiable risk factors (SMuRFless MI). Mortality is higher within 30 days of the event, as demonstrated in survival analyses from the SWEDEHEART registry.

Atherosclerosis 59

Atherosclerosis Plaque Myocardial Infarction Risk Factors 59

Frontiers in Cardiovascular Medicine

NOVEMBER 21, 2024

Individual outcomes, including all-cause mortality, myocardial infarction, and revascularization, also showed no significant differences between the two groups. Before propensity score (PS) matching, the POCE incidence was 3.1% in the BB group vs. 3.4% in the non-BB group [hazard ratio (HR) 0.86, 95% confidence interval (CI) 0.68–1.09,

Myocardial Infarction 45

Myocardial Infarction Kidney Disease Outcomes Research 45

Open Heart

JANUARY 19, 2025

Aim This study aimed to systematically review and analyse the existing evidence on outcomes of emergency transcatheter aortic valve implantation (eTAVI) and emergency balloon aortic valvuloplasty (eBAV) in CS patients. Despite advancements in emergency interventions, the optimal treatment approach remains uncertain.

Cardiogenic Shock 52

Cardiogenic Shock Aortic Stenosis Aortic valve 52

Heart BMJ

JULY 10, 2024

Background Despite restoration of epicardial blood flow in acute ST-elevation myocardial infarction (STEMI), inadequate microcirculatory perfusion is common and portends a poor prognosis. Intracoronary (IC) thrombolytic therapy can reduce microvascular thrombotic burden; however, contemporary studies have produced conflicting outcomes.

Myocardial Infarction 52

Myocardial Infarction Thrombolysis STEMI Outcomes 52

Frontiers in Cardiovascular Medicine

DECEMBER 9, 2024

Therefore, this meta-analysis aimed to estimate association between TMAO levels and the prognosis of patients with myocardial infarction (MI).MethodsWe Outcomes included MACE, all-cause mortality, recurrent MI, rehospitalization caused by heart failure, stroke, revascularization, SYNTAX score, and multivessel disease.

Myocardial Infarction 52

Myocardial Infarction Biomarkers Heart Failure Stroke 52