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BackgroundWeight-adjusted waist circumference index (WWI) is a novel index related to obesity and has been associated with the risk and prognosis of several diseases. Multiple logistic regression and restricted cubic spline (RCS) analyses were conducted to assess both linear and nonlinear associations between WWI and myocardialinfarction.
kg/m2), normal weight (18.524 kg/m2), overweight (2428 kg/m2), and obese (>28 kg/m2). kg/m2), normal weight (18.524 kg/m2), overweight (2428 kg/m2), and obese (>28 kg/m2). Journal of the American Heart Association, Ahead of Print. The primary outcome was inhospital allcause mortality.
BackgroundRecent evidence highlights an increasing incidence of myocardialinfarction in young women. years]) admitted to the China Chest Pain Center Database between 2016 and 2021.
They have a greater prevalence of obesity, dyslipidemia, metabolic syndrome and diabetes mellitus. Higher risk of myocardialinfarction, heart failure and atrial fibrillation was noted in spinal cord injury survivors compared to controls. Survivors with severe disability had the highest risk. Am J Phys Med Rehabil. 2023.12.010.
Introduction:The paucity of large-scale data exploring the effect of prior bariatric surgery on recurrent stroke outcomes in elderly obese stroke survivors led us to address the gap, with an emphasis on the risk of recurrent stroke and its trends.Methods:A retrospective study was conducted using National Inpatient Sample data from 2016-2019.
ET Main Tent (Hall B1) - A Double-blind, Randomized Placebo Procedure-controlled Trial of an Interatrial Shunt in Patients with HFrEF and HFpEF: Principal Results From the RELIEVE-HF Trial - Empagliflozin After Acute MyocardialInfarction: Results of the EMPACT-MI Trial - CSL112 (Apolipoprotein A-I) Infusions and Cardiovascular Outcomes in Patients (..)
Obesity is one of the biggest global health concerns we face today. Obesity is also a key driver of risk for cardiovascular disease. Although there are many factors linked to obesity, one factor is certain: excess caloric intake leads to an excess in the energy balance. Obesity (Silver Spring). hour sleep-per-night group.
Sodium/glucose cotransporter 2 (SGLT2) inhibitors are a novel class of anti-diabetic medications which have proved capable of providing breakthrough cardiovascular benefits in a variety of clinical scenarios, including patients with heart failure or obesity, irrespective of diabetic status.
Our primary CVD outcome was defined by a combined end point that included either incident myocardialinfarction, stroke, or heart failure.Results:Using a discovery/validation approach, 42 proteins were associated with our primary composite end point occurring in 1163 subjects. Thirteen proteins were related to all 3 outcomes.
The Minneapolis Heart Institute Foundation (MHIF) is presenting leading research focused on trends in ST-elevation myocardialinfarction (STEMI), the most severe form of a heart attack, at the American College of Cardiology’s Annual Scientific Session (ACC.24), 24), being held April 6-8 in Atltanta, GA.
Based on the finetuned NN, we predicted risk markers within an independent cohort of 48,376 patients with a history of T2D, ASCVD, or obesity and emulated a target trial to evaluate the subclinical effect of GLP1RA. Compared to the control group, the GLP1RA cohort had a higher baseline risk profile (BMI: 35.1 [SD
Background:A recent prospective study reported that myocardialinfarction (MI) was present in nearly half of ischemic stroke patients with substantially elevated troponin, with 1 in 5 having a type 1 MI. Stroke, Volume 56, Issue Suppl_1 , Page AWP141-AWP141, February 1, 2025.
Comorbidities such as PAD, depression, and other mental health disorders predict readmission after elective CAS, while heart failure, AKI, CAD, COPD, CKD, lipid disorders, DM, obesity, anemia, cancer, and dementia are predictive after elective CEA.
vs 61.07, p < 0.01), more often obese (12.15% vs 9.32%, p < 0.01), of the white race (55.82% vs 51%, p < 0.01), and considered long‐term users of anticoagulants (8.12% vs 5.34%, p < 0.01) when compared to the non‐AKI group. Patients with AKI were on average older (63.29
Anyway, I was invited to write the article by Dr Eric Westman, who was the guest editor for this edition of ‘ Current Opinion in Endocrinology, Diabetes and Obesity.’ There are numerous other conditions leading to this kind of damage, which can trigger thrombus formation, causing strokes and myocardialinfarctions.
low cholesterol), the total score can easily be taken to greater than 10 with other risk factors, including high blood pressure, obesity, inactivity, smoking etc. As you can see, statin therapy reduces the risk of heart attacks (myocardialinfarction) by close to 30%. But even if your cholesterol score is very small (i.e.
This imbalance is partly due to limited healthcare access, fewer preventive resources, and challenges in addressing risk factors such as obesity and diabetes. For example, the global spread of obesity, particularly among youth, has set the stage for a future pandemic of non-communicable diseases.
IntroductionIn developing countries, there is a notable scarcity of real-world data on adherence to optimal medical therapy (OMT) and its correlation with major cardiovascular adverse events (MACEs) after ST-elevation myocardialinfarction (STEMI). Patients were followed up for 4.5 ResultsWe included 349 patients with a mean age of 58.08
Can you please explain the concept of an obesity paradox? Salvatore Carbone, PhD: First, I’d like to point out that obesity is a major risk factor for cardiometabolic disease. 2, 3] This association is more pronounced for those with class I obesity, which is a body mass index (BMI) between 30-35 kg/m2.
New obesity medications such as GLP-1 agonists have shown significant reductions in weight in those with a prior heart attack. 2 Trends and Predictors of Participation in Cardiac Rehabilitation Following Acute MyocardialInfarction: Data From the Behavioral Risk Factor Surveillance System. J Am Heart Assoc. J Am Heart Assoc.
This analysis evaluated the efficacy and safety of bempedoic acid in people with obesity participating in the CLEAR (Cholesterol Lowering via Bempedoic Acid [ECT1002], an ACLInhibiting Regimen) Outcomes trial.MethodsCLEAR Outcomes randomized 13 970 patients to daily bempedoic acid 180 mg or placebo. and hsCRP of 23.2% at 6 months.
A-Fib, as the condition is commonly known, has been on the rise for at least the past decade, driven by the aging of the population, along with increasing rates of hypertension, diabetes and obesity. Earlier projections had estimated that 3.3 million U.S. The study appears Sept. 11 in the Journal of the American College of Cardiology JACC.
Major findings from the INTERHEART study reveal that stress is more common among cases of acute myocardialinfarction (AMI) compared to controls. Inflammation plays a pivotal role in both depression and obesity, while stress elevates cortisol levels, often initiating this cycle.
A-Fib, as the condition is commonly known, has been on the rise for at least the past decade, driven by the aging of the population, along with increasing rates of hypertension, diabetes and obesity. Earlier projections had estimated that 3.3 million U.S. The study appears Sept. 11 in the Journal of the American College of Cardiology JACC.
However, obesity (0.30, 0.11-0.85) Model fit was assessed using the Hosmer-Lemeshow test.Results:Among 142 eligible pre-ICH statin users (median age [IQR]: 77.5 [72-86] 72-86] years; 57.0% female; 66.0% non-Hispanic White [NHW]), 59 (41.6%) continued using statin post-ICH (median age [IQR]: 76 [73-85] years; 57.6% female; 69.5%
In this late-breaking session, Dr. Jorge Plutzky (United States of America) presented the SELECT study, demonstrating semaglutide’s cardiovascular benefits in overweight/obese patients with CVD but without T2D. Higher baseline hsCRP levels correlated with increased risks of MI, CVD death, and all-cause death.
3 Patients with ASCVD are at a higher risk for major adverse cardiovascular events (MACE) including heart attack or myocardialinfarction (MI), stroke, and cardiovascular (CV) death.4 Efficacy and Safety of Low-Dose Colchicine after MyocardialInfarction. 4 In the U.S. 12 Importantly, colchicine, 0.5 N Engl J Med.
Patients with a high risk of metabolic syndrome (>= 2 of the following: hypertension, diabetes, hyperlipidemia, or obesity) have a higher risk of AIS (1.37, 1.13 - 1.65), AMI (1.81, 1.19 - 2.75), and MACE (1.28, 1.13 - 1.44).Conclusions:Developing Results:Among 10,652 ICH patients (median age [IQR]: 70 [58 - 80] years; 47.7%
A rate of 15% of major depressive disorder has been reported in patients after myocardialinfarction or coronary artery bypass grafting, and this rate is >20% in patients with heart failure and is much higher in advanced heart failure.” Indeed, several studies have reported higher rates of depression among people with CVD.
EMPACT-MI 1 ( NCT04509674 ) studied the effects of empagliflozin in patients who have experienced myocardialinfarction (MI). STEP-HFpEF DM 5 ( NCT04916470 ) explored the effects of semaglutide in obesity-related HF with preserved ejection fraction (HFpEF) and type 2 diabetes. Here is our curated list of the top sessions.
37.6%, p < 0.001), obesity (9.2% CM‐HF patients had higher rates of in‐patient complications such as PEG placement, tracheostomy, sepsis, DVT or PE, pneumonia, UTI, AKI, myocardialinfarction, and intracerebral hemorrhage. 24.2%, p < 0.001), diabetes mellitus (39.7% 7.3%, p < 0.001). 22.3%, p= 0.321).
Lifestyle Habits: Obesity, smoking, excessive alcohol consumption, and lack of exercise can all negatively impact sexual function. Risk Factors for ED: Heart disease, specifically coronary artery disease (CAD) and acute myocardialinfarction (AMI), is closely linked to male erectile dysfunction.
Objective Historical reductions in cardiovascular disease (CVD) due to lifestyle and treatment improvements are now threatened by factors such as increasing obesity and diabetes, but the relative importance of different risk factors varies by CVD condition.
This is due to several factors, including the aging of the population, a rise in obesity, increased detection, and increased survival with AF along with other forms of CVD. Background Atrial fibrillation, the most sustained common arrhythmia, is increasing in incidence and prevalence in the United States and globally. million.
When one of these arteries becomes completely blocked by a blood clot, it results in a heart attack, also known as MI (Myocardialinfarction). When a person experiences a heart attack or myocardialinfarction, they may feel chest pain and other symptoms in different parts of their body. Maintain a healthy weight.
Scott Rankin The Impact of Mitral Disease Etiology on Operative Mortality After Mitral Valve Operations The Annals of Thoracic Surgery November 2018 Alice Wang Robotic Mitral Valve Repair in Older Individuals: An Analysis of The Society of Thoracic Surgeons Database The Annals of Thoracic Surgery November 2018 Mohamad Alaeddine Aortic clamping strategy (..)
Scott Rankin The Impact of Mitral Disease Etiology on Operative Mortality After Mitral Valve Operations The Annals of Thoracic Surgery November 2018 Alice Wang 1 Robotic Mitral Valve Repair in Older Individuals: An Analysis of The Society of Thoracic Surgeons Database The Annals of Thoracic Surgery November 2018 Mohamad Alaeddine 1 Aortic clamping (..)
SUMMIT Trial : Weekly subcutaneous tirzepatide showed significant reductions in CV death and HF-related events among patients with HFpEF and obesity. The NUDGE-FLU trial revealed cardiovascular-focused messaging increased flu vaccination rates in myocardialinfarction patients. Read the published study. Access the full study.
BackgroundAlthough reperfusion therapy has led to improvements in the acute phase of ST-segment elevation myocardialinfarction (STEMI), the incidence of major adverse cardiovascular events (MACE) following STEMI has not significantly decreased.
BackgroundThe mortality of patients with acute myocardialinfarction (MI) raised rapidly in last decade and obesity are becoming the major cause to CAD progression, thus inducing heart failure preserved ejection fraction (HFpEF). Also, SASPs decreased in hypoxic fibroblasts after OGN knockdown.
42% of adults are considered obese , increasing their risk of diabetes, hypertension, and cardiovascular issues. Emerging Risk Factors: Non-traditional factors such as the microbiome, pollution, and somatic mutations are increasingly linked to “SMuRFless” myocardialinfarction (MI) cases. In the U.S.,
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