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Nature Reviews Cardiology, Published online: 12 February 2025; doi:10.1038/s41569-025-01137-y Differing definitions and questionable prognostic significance have caused confusion and controversy around the applicability of the current definitions of periprocedural and perioperative myocardialinfarction in clinical practice.
Introduction ST-elevation myocardialinfarction (STEMI) is one of the most prevalent presentations in young patients. It is essential to emphasise that each minute of delay in providing medical care is negatively correlated to the patient’s prognosis.
Background Heart failure with preserved ejection fraction is a recognised outcome in patients with myocardialinfarction, although heart failure with reduced ejection fraction is more common. Among patients with myocardialinfarction, a 1-SD increase in pulse pressure was associated with a 1.60-fold m/s had a 2.10-fold
The function of oxygen gradients should be correlated with circulating natriuretic peptides to achieve better sensitivity in plasma measurements of natriuretic peptides in myocardialinfarction.
IntroductionCardiovascular diseases include myocardialinfarction, a high mortality disease. Myocardialinfarction patients are becoming younger, typically defined as patients under 45 years of age. We searched the WoSCC between 1980 and 2023 for research papers and reviews on myocardialinfarction in youth.
This study aimed to investigate the relationship between temperature and myocardialinfarction (MI) risk among migrants in Kuwait. With a large migrant population predominantly employed in physically demanding jobs, the exact effects and burdens of temperature exposure on cardiovascular risk among this population remain unknown.
ObjectiveThis study aimed to investigate the causal relationship between insomnia and the risk of myocardialinfarction (MI) and explore potential mediators such as smoking initiation, alcohol consumption and body mass index (BMI) using mendelian randomization (MR) analysis.MethodsData from 1,207,228 individuals of European ancestry were obtained from (..)
Despite improvements in clinical outcomes of acute myocardialinfarction (AMI), mortality rates remain high, indicating the need for further understanding of the pathogenesis and developing more effective cardiac protection strategies.
This narrative review aims to evaluate strategies for reducing door-to-balloon (D2B) time in ST-elevation myocardialinfarction (STEMI) patients, focusing on pre-hospital, in-hospital, and technological innovations, as well as addressing challenges to ensure sustainability.
However, studies on diagnostic markers related to cellular senescence in acute myocardialinfarction (AMI) have not been reported. IntroductionCellular senescence can cause heart failure.
We aimed to determine the risk of myocardialinfarction (MI) and stroke after BSI. Background Cardiovascular disease (CVD) events triggered by inflammation are an underappreciated and poorly quantified cause of morbidity and mortality in patients with bloodstream infections (BSIs).
Heart failure (HF) is one of the significant complications in patients with myocardialinfarction (MI), leading to increased risk for cardiovascular morbidity and mortality. 2 However, mortality rate is greater in HF cases developing >3 days following MI compared with less than or equal to 3 days after MI.
Background Atrial fibrillation (AF) and acute myocardialinfarction (AMI) share risk factors and are bidirectionally associated. Several studies found higher risks of outcomes in individuals with both conditions. Whether the risks of outcomes differ according to temporal order of AF and AMI is unclear.
ObjectiveThis study aimed to evaluate the correlation between aerobic exercise intensity based on the 6min walk test (6MWT) and the anaerobic threshold (AT)-based equivalent in patients with acute myocardialinfarction (AMI).
Yet, the impact of GLP-1RA treatment before ST-segment elevation myocardialinfarction (STEMI) on. Glucagon-like peptide-1 receptor agonist (GLP-1RA) treatment reduces cardiovascular events in type 2 diabetes.
However, whether immediate blood glucose and FIB levels affect coronary blood flow during primary percutaneous coronary intervention (PCI) remains unclear.ObjectiveTo explore the correlation between admission blood glucose (ABG), fibrinogen (FIB) and slow blood flow during primary PCI for acute ST segment elevation myocardialinfarction (STEMI).MethodsA
Background Despite limited beneficial evidence, mechanical circulatory support (MCS) is commonly used in patients with acute myocardialinfarction-related cardiogenic shock (AMI-CS). In this Dutch registry, we investigated MCS usage, associated patient characteristics and clinical outcomes.
In the beginning of the 20th century, the first reports of the clinical manifestations of myocardialinfarction (MI) appeared, followed around a decade later by reports regarding the electrocardiographic (ECG) changes associated with MI ( figure 1 ).
In a randomized trial involving patients with acute myocardialinfarction, colchicine did not decrease the risk of major adverse cardiovascular events over a median follow-up period of 3 years.
a developer of cellular and cell-derived therapeutics for the treatment of cardiovascular and pulmonary diseases, announced success from a collaborative Phase II trial of ProtheraCytes for the treatment of acute myocardialinfarction (AMI) led by CellProthera , as well as plans to continue the relationship into Phase III.
The presence of atrial arrhythmias during stress testing at all time points was also associated with later diagnosis of coronary artery disease or myocardialinfarction: OR 1.82 (95% CI 1.09, 3.03), p=0.02. However, it is linked to subsequent diagnosis of AF, coronary artery disease and myocardialinfarction.
Curtain etal1 performed an analysis of the VALIANT (Valsartan in Acute MyocardialInfarction) and PARADISE-MI (Prospective ARNi vs ACE Inhibitor Trial to Determine Superiority in Reducing Heart Failure Events After MI) trials to evaluate whether risk of sudden cardiac arrest (SCA) following acute myocardialinfarction (MI) has changed over time.
This post hoc analysis of the Ticagrelor vs Clopidogrel in Stabilized Patients With Acute MyocardialInfarction (TALOS-AMI) randomized clinical trial investigates the efficacy and safety of the de-escalation strategy of switching from ticagrelor to clopidogrel vs dual antiplatelet therapy with ticagrelor in stabilized patients with acute myocardial (..)
The development of coronary care units is often credited for a dramatic decline in mortality rates after acute myocardialinfarction throughout the 1960s. As the underlying patient population became progressively sicker, changes in organizational structure, staffing, care delivery, and training paradigms lagged.
The goal of the CLEAR SYNERGY OASIS 9 trial was to determine the long-term cardiovascular (CV) effects of colchicine following percutaneous coronary intervention (PCI) for ST-segment elevation or large non–ST-segment elevation myocardialinfarction (STEMI or NSTEMI, respectively).
Hemoglobin (Hb) threshold for red cell transfusion in myocardialinfarction (MI) with anemia has been a matter of debate. Previous randomized trials have not consistently shown a benefit of liberal transfusion strategy.
Nature Reviews Cardiology, Published online: 03 May 2024; doi:10.1038/s41569-024-01031-z In the AEGIS-II trial, infusion of apolipoprotein A-I to increase cholesterol efflux capacity did not improve outcomes in patients with acute myocardialinfarction.
Background The diagnosis of a left ventricular (LV) thrombus in patients with ST-segment elevation myocardialinfarction (STEMI) remains challenging. The aim of the current study is to characterize clinical predictors for LV thrombus formation, as detected by cardiac magnetic resonance imaging (CMRI). and 59%, respectively.
Stress hyperglycemia, which is associated with poor prognosis in patients with acute myocardialinfarction (AMI), can be determined using the stress hyperglycemia ratio (SHR). Impaired left ventricular functio.
This feature about a man who had had a myocardialinfarction with preserved left ventricular ejection fraction offers a case vignette accompanied by two essays, one supporting the use of beta-blockers after discharge and the other recommending no use of beta-blockers.
The aim of this study was to investigate the difference between perceived and calculated diabetes risks among post-myocardialinfarction (AMI) patients using the Finnish Diabetes Risk Score (FINDRISC).
Ankeet Bhatt, MD, MBA, discusses a NUDGE-FLU analysis from ACC.24 24 examining effect of the CV gain-framed nudge in patients with and without history of AMI.
The goal of the CLEAR SYNERGY (OASIS 9) spironolactone trial was to determine the potential cardiovascular (CV) benefit of spironolactone following percutaneous coronary intervention (PCI) for ST-segment or large non–ST-segment elevation myocardialinfarction (STEMI or NSTEMI, respectively) regardless of post-MI left ventricular ejection fraction (..)
BackgroundCardiac rupture (CR) after acute myocardialinfarction (AMI) is a fatal mechanical complication. The early identification of factors related to CR in high-risk cases may reduce mortality. and in-hospital mortality was approximately 57%.
The goal of the REDUCE-AMI trial was to evaluate the potential benefit of beta-blockade following acute myocardialinfarction (AMI) in patients with preserved left ventricular ejection fraction (LVEF) in the modern era of coronary revascularization and medical therapy.
(MedPage Today) -- Influenza infection was associated with an increased risk of acute myocardialinfarction (MI), especially for those without a prior hospitalization for coronary artery disease (CAD), according to a Dutch observational case series.
It is well-known that systemic inflammation plays a crucial role in the pathogenesis and prognosis of acute myocardialinfarction (AMI). The systemic immune-inflammation index (SII, platelet × neutrophil/lymph.
Multiple logistic regression and restricted cubic spline (RCS) analyses were conducted to assess both linear and nonlinear associations between WWI and myocardialinfarction. Subgroup analyses and interaction tests were also performed.ResultsAmong the 31,535 participants analyzed, 1,449 (4.82%) had experienced a myocardialinfarction.
The impact of sodiumglucose cotransporter-2 (SGLT2) inhibitors on mortality following myocardialinfarction (MI) remains uncertain. Additionally, the role of type 2 diabetes mellitus (T2DM) and heart failure.
Both the COMPLETE and PRAMI trial findings supported the benefits of complete revascularization over culprit-only percutaneous coronary intervention (PCI) in patients presenting with myocardialinfarction (MI) and multivessel coronary artery disease.
Specific cardiovascular diseases, such as acute myocardialinfarction, arrhythmias, pulmonary hypertension and pericarditis, were also pointed. SiO2 exposure was linked to an increased risk of myocardialinfarction, with potential mechanisms involving inflammation and platelet activation.
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