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Nature Reviews Cardiology, Published online: 12 February 2025; doi:10.1038/s41569-025-01137-y Differing definitions and questionable prognostic significance have caused confusion and controversy around the applicability of the current definitions of periprocedural and perioperative myocardialinfarction in clinical practice.
Introduction ST-elevation myocardialinfarction (STEMI) is one of the most prevalent presentations in young patients. It is essential to emphasise that each minute of delay in providing medical care is negatively correlated to the patient’s prognosis.
The function of oxygen gradients should be correlated with circulating natriuretic peptides to achieve better sensitivity in plasma measurements of natriuretic peptides in myocardialinfarction.
IntroductionCardiovascular diseases include myocardialinfarction, a high mortality disease. Myocardialinfarction patients are becoming younger, typically defined as patients under 45 years of age. We searched the WoSCC between 1980 and 2023 for research papers and reviews on myocardialinfarction in youth.
ObjectiveThe prevalence of acute myocardialinfarction, a severe ischemic cardiac disease, is on the rise annually. Over the past two decades, studies related to angiogenesis in acute myocardialinfarction have increased rapidly. The collection of literature was gathered using the Web of Science Core Collection database.
ObjectiveThis study aimed to investigate the causal relationship between insomnia and the risk of myocardialinfarction (MI) and explore potential mediators such as smoking initiation, alcohol consumption and body mass index (BMI) using mendelian randomization (MR) analysis.MethodsData from 1,207,228 individuals of European ancestry were obtained from (..)
Despite improvements in clinical outcomes of acute myocardialinfarction (AMI), mortality rates remain high, indicating the need for further understanding of the pathogenesis and developing more effective cardiac protection strategies.
However, studies on diagnostic markers related to cellular senescence in acute myocardialinfarction (AMI) have not been reported. IntroductionCellular senescence can cause heart failure.
The main content of this paper is to explore the application of stem cells and gene technology in the treatment of myocardialinfarction (MI). It has become an urgent task for clinical medicine to seek new and better treatment.
However, the association between vessel-level coronary atherosclerotic plaque activity and the incidence of vessel-level myocardialinfarction (MI) has not been fully explored. This included an elevated risk of cardiac death or myocardialinfarction (HR: 2.43; 95% CI: 1.37-4.30; 4.39; P = 0.002) myocardialinfarctions.
ObjectiveThis study aimed to evaluate the correlation between aerobic exercise intensity based on the 6min walk test (6MWT) and the anaerobic threshold (AT)-based equivalent in patients with acute myocardialinfarction (AMI).
Occlusion myocardialinfarction is a clinical diagnosis Written by Willy Frick (@Willyhfrick). St depression in lead AVL differentiates inferior st-elevation myocardialinfarction from pericarditis. link] Opiates are associated with worse outcomes in MyocardialInfarction. Circulation , 130 (25). Worrall, C.,
This secondary analysis of the Valsartan in Acute MyocardialInfarction (VALIANT) and Prospective ARNi vs ACE Inhibitor Trial to Determine Superiority in Reducing Heart Failure Events After MI (PARADISE-MI) randomized clinical trials investigates the changes over time in sudden death rate after myocardialinfarction and the characteristics of people (..)
Background Atrial fibrillation (AF) and acute myocardialinfarction (AMI) share risk factors and are bidirectionally associated. Several studies found higher risks of outcomes in individuals with both conditions. Whether the risks of outcomes differ according to temporal order of AF and AMI is unclear.
Yet, the impact of GLP-1RA treatment before ST-segment elevation myocardialinfarction (STEMI) on. Glucagon-like peptide-1 receptor agonist (GLP-1RA) treatment reduces cardiovascular events in type 2 diabetes.
IntroductionAcute coronary syndrome refers to a group of diseases characterized by sudden, decreased blood supply to the heart muscle that results in cell death, also known as acute myocardialinfarction. The majority of patients (67.9%) have been diagnosed with ST- Elevated MyocardialInfarction and were classified as Killip class I.
However, whether immediate blood glucose and FIB levels affect coronary blood flow during primary percutaneous coronary intervention (PCI) remains unclear.ObjectiveTo explore the correlation between admission blood glucose (ABG), fibrinogen (FIB) and slow blood flow during primary PCI for acute ST segment elevation myocardialinfarction (STEMI).MethodsA
Background Despite limited beneficial evidence, mechanical circulatory support (MCS) is commonly used in patients with acute myocardialinfarction-related cardiogenic shock (AMI-CS). In this Dutch registry, we investigated MCS usage, associated patient characteristics and clinical outcomes.
In the beginning of the 20th century, the first reports of the clinical manifestations of myocardialinfarction (MI) appeared, followed around a decade later by reports regarding the electrocardiographic (ECG) changes associated with MI ( figure 1 ).
a developer of cellular and cell-derived therapeutics for the treatment of cardiovascular and pulmonary diseases, announced success from a collaborative Phase II trial of ProtheraCytes for the treatment of acute myocardialinfarction (AMI) led by CellProthera , as well as plans to continue the relationship into Phase III.
In a randomized trial involving patients with acute myocardialinfarction, colchicine did not decrease the risk of major adverse cardiovascular events over a median follow-up period of 3 years.
Curtain etal1 performed an analysis of the VALIANT (Valsartan in Acute MyocardialInfarction) and PARADISE-MI (Prospective ARNi vs ACE Inhibitor Trial to Determine Superiority in Reducing Heart Failure Events After MI) trials to evaluate whether risk of sudden cardiac arrest (SCA) following acute myocardialinfarction (MI) has changed over time.
The development of coronary care units is often credited for a dramatic decline in mortality rates after acute myocardialinfarction throughout the 1960s. As the underlying patient population became progressively sicker, changes in organizational structure, staffing, care delivery, and training paradigms lagged.
Objective In the COVERT-MI randomised placebo-controlled trial, oral administration of high-dose colchicine at the time of reperfusion and for 5 days in acute ST-elevated myocardialinfarction did not reduce infarct size but was associated with a significant increase in left ventricular thrombus (LVT) in comparison to placebo.
The goal of the CLEAR SYNERGY OASIS 9 trial was to determine the long-term cardiovascular (CV) effects of colchicine following percutaneous coronary intervention (PCI) for ST-segment elevation or large non–ST-segment elevation myocardialinfarction (STEMI or NSTEMI, respectively).
Ankeet Bhatt, MD, MBA, discusses a NUDGE-FLU analysis from ACC.24 24 examining effect of the CV gain-framed nudge in patients with and without history of AMI.
Background The diagnosis of a left ventricular (LV) thrombus in patients with ST-segment elevation myocardialinfarction (STEMI) remains challenging. The aim of the current study is to characterize clinical predictors for LV thrombus formation, as detected by cardiac magnetic resonance imaging (CMRI). and 59%, respectively.
Stress hyperglycemia, which is associated with poor prognosis in patients with acute myocardialinfarction (AMI), can be determined using the stress hyperglycemia ratio (SHR). Impaired left ventricular functio.
ObjectivesExercise training is a rehabilitative approach to improve cardiac function in patients with myocardialinfarction. However, evidence on the effectiveness of exercise training in these patients remains limited.
The aim of this study was to investigate the difference between perceived and calculated diabetes risks among post-myocardialinfarction (AMI) patients using the Finnish Diabetes Risk Score (FINDRISC).
BackgroundCardiac rupture (CR) after acute myocardialinfarction (AMI) is a fatal mechanical complication. The early identification of factors related to CR in high-risk cases may reduce mortality. and in-hospital mortality was approximately 57%.
(MedPage Today) -- Influenza infection was associated with an increased risk of acute myocardialinfarction (MI), especially for those without a prior hospitalization for coronary artery disease (CAD), according to a Dutch observational case series.
This post hoc analysis of a randomized clinical trial analyzes imaging data for atheroma volume at the lesion level from patients who received intensive lipid-lowering therapy with alirocumab plus statin compared with a statin alone.
Multiple logistic regression and restricted cubic spline (RCS) analyses were conducted to assess both linear and nonlinear associations between WWI and myocardialinfarction. Subgroup analyses and interaction tests were also performed.ResultsAmong the 31,535 participants analyzed, 1,449 (4.82%) had experienced a myocardialinfarction.
The impact of sodiumglucose cotransporter-2 (SGLT2) inhibitors on mortality following myocardialinfarction (MI) remains uncertain. Additionally, the role of type 2 diabetes mellitus (T2DM) and heart failure.
BackgroundCardiorenal syndrome type 1 is characterized by the development of acute kidney injury following acute cardiac illness and notably acute myocardialinfarction (MI). Journal of the American Heart Association, Ahead of Print.
Specific cardiovascular diseases, such as acute myocardialinfarction, arrhythmias, pulmonary hypertension and pericarditis, were also pointed. SiO2 exposure was linked to an increased risk of myocardialinfarction, with potential mechanisms involving inflammation and platelet activation.
HF, heart failure; LVEF, left ventricular ejection fraction; MI, myocardialinfarction. Abstract Aims In the EMPACT-MI trial, empagliflozin reduced heart failure (HF) hospitalizations but not mortality in acute myocardialinfarction (MI). Glycaemic status and diabetes in EMPACT-MI.
The primary outcome was device success and allcause death, while secondary outcomes included myocardialinfarction, stroke, and heart failure hospitalization rates at 30day and intermediateterm followup. Studies with <5 patients were excluded. A fixedeffects metaanalysis was used to estimate pooled rates.
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